Cited by 82Fatty Acid Research and HealthEdible Oils Quality and AnalysisMeat and Animal Product Quality

Conjugated linoleic acid: A potent fatty acid linked to animal and human health

Shokryazdan, Parisa, Rajion, Mohamed Ali, Meng, Goh Yong, Boo, Liang Juan, Ebrahimi, Mahdi, Royan, Maryam, Sahebi, Mahbod, Azizi, Parisa +2 more·2017·Critical Reviews in Food Science and Nutrition

Abstract

Conjugated linoleic acid (CLA) is a mixture of isomers of linoleic acid (C18:2 n-6), which is mostly found in the ruminant meat and dairy products. The CLA is known to have many potential health benefits, and considered a potent powerful fatty acid, which is linked to animal and human health. The present work aims to discuss the source and production, mechanism of action, and effects of CLA on humans, poultry, and ruminants by reviewing the recent studies carried out on CLA. Despite most of the recent studies indicating beneficial effects of CLA on improving body weight control parameters, its effects on reducing risk factors of cardiovascular diseases (CVD), inflammation, blood glucose, and insulin are still controversial, and need to be further studied in different hosts.

Integrity signals

Registry

Crossref · 10.1080/10408398.2015.1060190

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123 of 123 references verified0 citation errors · 0 not checkable

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  • The t10,c12 isomer has the most potent effect of CLA in preventing cell proliferation and inducing apoptosis in cancer cells.

    “This isomer is known to have the most potent effect of CLA in preventing cell proliferation and inducing apoptosis in cancer cells [256].”

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Authors
Shokryazdan, P., Rajion, M. A., Meng, G. Y., Boo, L. J., Ebrahimi, M., Royan, M., Sahebi, M., Azizi, P., Abiri, R., & Jahromi, M. F.
Affiliations
  • Universiti Putra Malaysia (MY)
  • Agricultural Biotechnology Research Institute of Iran (IR)
Corresponding author
Rajion, Mohamed Ali
Venue
Critical Reviews in Food Science and Nutrition
Published
2015-08-07
Volume
57
Issue
13
Pages
2737-2748
ISSN
  • 1040-8398 (ISSN-L)
  • 1549-7852
OpenAlex
W1952903824
Cited by
82
References
124
Citations by year
2026: 7 · 2025: 7 · 2024: 12 · 2023: 9 · 2022: 5 · 2021: 9 · 2020: 10 · 2019: 8 · 2018: 11 · 2017: 3 · 2016: 1
FWCI
4.82
Type
journal article
Language
en
Open access
closed
Locations
  • Critical Reviews in Food Science and Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia) (acceptedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
  • Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Meat and Animal Product Quality
Keywords
conjugated linoleic acid, linoleic acid isomers, ruminant meat, dairy products, weight management, cardiovascular risk factors, inflammation, blood glucose, insulin, poultry, ruminants, human health effects
MeSH terms
Animals, Dairy Products, Fatty Acids, Food Handling, Humans, Insulin Resistance, Meat, Nutritive Value, Linoleic Acids, Conjugated

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