Cited by 318Probiotics and Fermented FoodsDigestive system and related healthGastrointestinal motility and disorders

The effects of probiotics in lactose intolerance: A systematic review

Oak, Sophia J., Jha, Rajesh·2019·Critical Reviews in Food Science and Nutrition

Abstract

Over 60 percent of the human population has a reduced ability to digest lactose due to low levels of lactase enzyme activity. Probiotics are live bacteria or yeast that supplements the gastrointestinal flora. Studies have shown that probiotics exhibit various health beneficial properties such as improvement of intestinal health, enhancement of the immune responses, and reduction of serum cholesterol. Accumulating evidence has shown that probiotic bacteria in fermented and unfermented milk products can be used to alleviate the clinical symptoms of lactose intolerance (LI). In this systematic review, the effectiveness of probiotics in the treatment of LI was evaluated using 15 randomized double-blind studies. Eight probiotic strains with the greatest number of proven benefits were studied. Results showed varying degrees of efficacy but an overall positive relationship between probiotics and lactose intolerance.

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Crossref · 10.1080/10408398.2018.1425977

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Authors
Oak, S. J., & Jha, R.
Affiliations
University of Hawaiʻi at Mānoa (US)
Corresponding author
Jha, Rajesh
Venue
Critical Reviews in Food Science and Nutrition
Published
2018-02-09
Volume
59
Issue
11
Pages
1675-1683
ISSN
  • 1040-8398 (ISSN-L)
  • 1549-7852
OpenAlex
W2793459212
Cited by
318
References
48
Citations by year
2026: 23 · 2025: 23 · 2024: 45 · 2023: 44 · 2022: 49 · 2021: 60 · 2020: 48 · 2019: 9 · 2018: 16
FWCI
3.36
Type
journal article
Language
en
Open access
closed
Locations
  • Critical Reviews in Food Science and Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Digestive system and related health
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Keywords
probiotics, lactose intolerance, lactase deficiency, fermented milk, probiotic strains, gut health, immune response, serum cholesterol, symptom relief
MeSH terms
Gastrointestinal Microbiome, Animals, Bacteria, Cholesterol, Digestion, Double-Blind Method, Fatty Acids, Volatile, Fermentation, Humans, Lactose, Lactose Intolerance, Milk, Yeasts, Randomized Controlled Trials as Topic, Databases, Factual, Dietary Supplements, Probiotics

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