Latilactobacillus sakei : a candidate probiotic with a key role in food fermentations and health promotion
Abstract
Latilactobacillus sakei is used extensively in industrial production and food fermentations. The species is primarily derived from fermented meat and vegetable products and is also found in human feces. Genomics and metabolomics have revealed unique metabolic pathways in L. sakei and molecular mechanisms underlying its competitive advantages in different habitats, which are mostly attributed to its flexible carbohydrate metabolism, cold tolerance, acid and salt tolerance, ability to cope with oxygen changes, and heme uptake. In recent years, probiotic effects of L. sakei and its metabolites have been identified, including the ability to effectively alleviate metabolic syndrome, inflammatory bowel disease, and atopic dermatitis. This review summarizes the genomic and metabolic characteristics of L. sakei and its metabolites and describes their applications, laying a foundation for their expanded use across the food and healthcare industries.
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Fermented meat was characterized by L. sakei, S. equorum, and Latilactobacillus curvatus.
“fermented meat, for instance, was characterized by L. sakei (typically present during ripening, aging, and fermentation), S. equorum , and Latilactobacillus curvatus .”
From Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome. (2024) · cites this paper as [98]
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Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome.
Carlino, N., Blanco-Míguez, A., Punčochář, M., Mengoni, C., Pinto, F., Tatti, A., Manghi, P., Armanini, F., Avagliano, M., Barcenilla, C., et al. (2024) · Cell · doi:10.1016/j.cell.2024.07.039 · Cited by 146 · see citing works
“98 Non-fermented meat, instead, was enriched in three distinct SGBs of Pseudomonas fragi (i.e., SGB12106 corresponding to Pseudomonas_E bubulae in GTDB, 91 SGB12107— Pseudomonas_E fragi , and SGB12108— Pseudomonas_E fragi_D ), a species associated with dairy and raw meat spoilage.”
Bae, C.-I., Gwak, Y.-S., Eom, S.-J., Lee, S., & Kim, M.-J. (2025) · Food Science and Biotechnology · doi:10.1007/s10068-024-01739-1 · Cited by 4 · see citing works
- Authors
- Yu, L., Chen, Y., Duan, H., Qiao, N., Wang, G., Zhao, J., Zhai, Q., Tian, F., & Chen, W.
- Affiliations
- Jiangnan University (CN)
- University of Alberta (CA)
- Corresponding author
- Tian, Fengwei
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2022-08-23
- Volume
- 64
- Issue
- 4
- Pages
- 978-995
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W4292739012
- Cited by
- 33
- References
- 142
- Citations by year
- 2026: 11 · 2025: 9 · 2024: 9 · 2023: 4
- FWCI
- 0.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Food Science and Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- Lactobacillus sakei, probiotics, fermented meat products, fermented vegetables, carbohydrate metabolism, cold tolerance, heme uptake, bacterial metabolites, metabolic syndrome, inflammatory bowel disease, atopic dermatitis, health promotion
- MeSH terms
- Latilactobacillus sakei, Fermentation, Health Promotion, Humans, Lactobacillus, Probiotics
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