Negative affect heightens opiate withdrawal-induced hyperalgesia in heroin dependent individuals

The CES-D Scale: A Self-Report Depression Scale for Research in the General Population

Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267 · see citing works

Measuring emotion: The self-assessment manikin and the semantic differential

Bradley, M. M., & Lang, P. J. (1994) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/0005-7916(94)90063-9 · Cited by 9,538 · see citing works

Emotion circuits in the brain

LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444 · see citing works

Drug Addiction, Dysregulation of Reward, and Allostasis

Koob, G. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00195-0 · Cited by 2,953 · see citing works

The emotion probe. Studies of motivation and attention.

Lang, P. J. (1995) · American Psychologist · doi:10.1037/0003-066x.50.5.372 · Cited by 2,846 · see citing works

The emotion probe: Studies of motivation and attention.

Lang, P. J. (1995) · American Psychologist · doi:10.1037//0003-066x.50.5.372 · Cited by 2,752 · see citing works

Drug abuse: hedonic homeostatic dysregulation

Koob, G. F., & Moal, M. L. (1997) · Science · doi:10.1126/science.278.5335.52 · Cited by 2,535 · see citing works

Genetic basis for individual variations in pain perception and the development of a chronic pain condition

Diatchenko, L., Slade, G. D., Nackley, A. G., Bhalang, K., Sigurdsson, A., Belfer, I., Goldman, D., Xu, K., Shabalina, S. A., Shagin, D., et al. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi013 · Cited by 1,280 · see citing works

Opioid-induced Hyperalgesia: A Qualitative Systematic Review

Angst, M. S., & Clark, J. D. (2006) · Anesthesiology · doi:10.1097/00000542-200603000-00025 · Cited by 1,188 · see citing works

Neurobehavioural mechanisms of reward and motivation

Robbins, T. W., & Everitt, B. J. (1996) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(96)80077-8 · Cited by 1,187 · see citing works

Neural organization of the defensive behavior system responsible for fear

Fanselow, M. S. (1994) · Psychonomic Bulletin & Review · doi:10.3758/bf03210947 · Cited by 1,000 · see citing works

Mechanisms of hyperalgesian and morphine tolerance: a current view of their possible interactions

Mao, J., Price, D. D., & Mayer, D. J. (1995) · Pain · doi:10.1016/0304-3959(95)00073-2 · Cited by 817 · see citing works

Cognitive modulation of pain: how do attention and emotion influence pain processing?

Villemure, C., & Bushnell, C. M. (2002) · Pain · doi:10.1016/s0304-3959(02)00007-6 · Cited by 728 · see citing works

The amygdala and persistent pain

Neugebauer, V., Li, W., Bird, G. C., & Han, J. S. (2004) · The Neuroscientist · doi:10.1177/1073858403261077 · Cited by 719 · see citing works

Neurobiological mechanisms for opponent motivational processes in addiction

Koob, G. F., & Moal, M. L. (2008) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2008.0094 · Cited by 702 · see citing works

Two New Rating Scales for Opiate Withdrawal

Handelsman, L., Cochrane, K. J., Aronson, M. J., Ness, R. C., Rubinstein, K. J., & Kanof, P. D. (1987) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952998709001515 · Cited by 599 · see citing works

Viewing facial expressions of pain engages cortical areas involved in the direct experience of pain

Botvinick, M., Jha, A. P., Bylsma, L. M., Fabian, S., Solomon, P. E., & Prkachin, K. M. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.11.043 · Cited by 589 · see citing works

Opioid-induced Hyperalgesia in Humans

Chu, L. F., Angst, M. S., & Clark, J. D. (2008) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e31816b2f43 · Cited by 572 · see citing works

Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis

Pich, E., Lorang, M., Yeganeh, M., Rodriguez de Fonseca, F., Raber, J., Koob, G., & Weiss, F. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-08-05439.1995 · Cited by 565 · see citing works

Borderline personality disorder and substance use disorders A review and integration

Trull, T. (2000) · Clinical Psychology Review · doi:10.1016/s0272-7358(99)00028-8 · Cited by 520 · see citing works

Untitled work

(1989) · Journal of Psychophysiology · Cited by 489 · see citing works

Editorial The need of a taxonomy

&NA;, &. (1979) · Pain · doi:10.1016/0304-3959(79)90046-0 · Cited by 413 · see citing works

Emotion, motivation, and the brain: Reflex foundations in animal and human research

Lang, P. J., & Davis, M. (2006) · Progress in Brain Research · doi:10.1016/s0079-6123(06)56001-7 · Cited by 410 · see citing works

Pain and Emotion: Effects of Affective Picture Modulation

Meagher, M. W., Arnau, R. C., & Rhudy, J. L. (2001) · Psychosomatic Medicine · doi:10.1097/00006842-200101000-00010 · Cited by 342 · see citing works

Effect of ethanol on the hypothalamic-pituitary-adrenal axis in the rat: role of corticotropin-releasing factor (CRF).

RIVIER, C. L., BRUHN, T. O., & Vale, W. G. (1984) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)21776-1 · Cited by 328 · see citing works

Progressive enhancement of delayed hyperalgesia induced by repeated heroin administration: a sensitization process

Célèrier, E., Laulin, J.-P., Corcuff, J.-B., Le Moal, M., & Simonnet, G. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-11-04074.2001 · Cited by 315 · see citing works

Piecing together the Puzzle of Basal Forebrain Anatomy

Heimer, L., & Alheid, G. F. (1991) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4757-0145-6_1 · Cited by 310 · see citing works

Real-Time Electronic Diary Reports of Cue Exposure and Mood in the Hours Before Cocaine and Heroin Craving and Use

Epstein, D. H., Willner‐Reid, J., Vahabzadeh, M., Mezghanni, M., Lin, J., & Preston, K. L. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.509 · Cited by 301 · see citing works

Opioid-induced hyperalgesia: abnormal or normal pain?

Simonnet, G., & Rivat, C. (2003) · NeuroReport · doi:10.1097/00001756-200301200-00001 · Cited by 273 · see citing works

Structural equation model testing and the quality of natural killer cell activity measurements

Hayduk, L. A., Pazderka, H., Cummings, G. G., Levers, M. J., & Beres, M. A. (2005) · BMC Medical Research Methodology · doi:10.1186/1471-2288-5-1 · Cited by 258 · see citing works

Affective pictures processing, attention, and pain tolerance

de Wied, M. A., & Verbaten, M. N. (2001) · Pain · doi:10.1016/s0304-3959(00)00400-0 · Cited by 248 · see citing works

Pleasure Rather Than Salience Activates Human Nucleus Accumbens and Medial Prefrontal Cortex

Sabatinelli, D., Bradley, M. M., Lang, P. J., Costa, V. D., & Versace, F. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00230.2007 · Cited by 225 · see citing works

Challenges in the manipulation, assessment and interpretation of craving relevant variables

Tiffany, S. T., Carter, B. L., & Singleton, E. G. (2000) · Addiction · doi:10.1046/j.1360-0443.95.8s2.7.x · Cited by 221 · see citing works

The behavioural management of anxiety, depression and pain

Merskey, H. (1979) · Pain · doi:10.1016/0304-3959(79)90175-1 · Cited by 209 · see citing works

Hyperalgesia during Naloxone-Precipitated Withdrawal from Morphine Is Associated with Increased On-Cell Activity in the Rostral Ventromedial Medulla

Bederson, J. B., Fields, H. L., & Barbaro, N. M. (1990) · Somatosensory & Motor Research · doi:10.3109/08990229009144706 · Cited by 182 · see citing works

Opiate tolerance to daily heroin administration: an apparent phenomenon associated with enhanced pain sensitivity

Laulin, J. P., Célèrier, E., Larcher, A., Le Moal, M., & Simonnet, G. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00652-6 · Cited by 179 · see citing works

Is Paradoxical Pain Induced by Sustained Opioid Exposure an Underlying Mechanism of Opioid Antinociceptive Tolerance?

King, T. E., Ossipov, M. H., Vanderah, T. W., Porreca, F., & Lai, J. Y. (2005) · Neurosignals · doi:10.1159/000087658 · Cited by 175 · see citing works

The role of emotion in pain modulation.

Rhudy, J. L., & Meagher, M. W. (2001) · Current Opinion in Psychiatry · doi:10.1097/00001504-200105000-00012 · Cited by 170 · see citing works

Cold-pressor pain tolerance in opiate and cocaine abusers: Correlates of drug type and use status

Compton, M. A. (1994) · Journal of Pain and Symptom Management · doi:10.1016/0885-3924(94)90203-8 · Cited by 164 · see citing works

Lack of interchangeability between visual analogue and verbal rating pain scales: a cross sectional description of pain etiology groups

Lund, I., Lundeberg, T., Sandberg, L., Budh, C. N., Kowalski, J. H., & Svensson, E. (2005) · BMC Medical Research Methodology · doi:10.1186/1471-2288-5-31 · Cited by 162 · see citing works

Pain Genes

Foulkes, T., & Wood, J. N. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000086 · Cited by 158 · see citing works

Emotional Modulation of Pain: Is It the Sensation or What We Recall?

Godinho, F. L. F., Magnin, M., Frot, M., Perchet, C., & Garcı́a-Larrea, L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2260-06.2006 · Cited by 155 · see citing works

Laboratory induction of mood states through the reading of self-referent mood statements: Affective changes or demand characteristics?

Polivy, J., & Doyle, C. (1980) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.89.2.286 · Cited by 152 · see citing works

Mapping study of somatosensory evoked potentials during selective spatial attention

Garcı́a-Larrea, L., Bastuji, H., & Mauguı̀ere, F. (1991) · Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section · doi:10.1016/0168-5597(91)90122-e · Cited by 151 · see citing works

Corticotropin releasing factor, stress and behavior

Koob, G. F., Heinrichs, S. C., Menzaghi, F., Pich, E. M., & Britton, K. T. (1994) · Seminars in Neuroscience · doi:10.1006/smns.1994.1029 · Cited by 141 · see citing works

Withdrawal hyperalgesia after acute opioid physical dependence in nonaddicted humans: a preliminary study

Compton, P., Athanasos, P., & Elashoff, D. (2003) · The Journal of Pain · doi:10.1016/j.jpain.2003.08.003 · Cited by 138 · see citing works

Pleasure into pain: The consequences of long-term opioid use

White, J. M. (2004) · Addictive Behaviors · doi:10.1016/j.addbeh.2004.06.007 · Cited by 118 · see citing works

Vocalizations during withdrawal from opiates and cocaine: possible expressions of affective distress

Covington, H. E., & Miczek, K. A. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01558-9 · Cited by 118 · see citing works

Laboratory induction of mood states through the reading of self-referent mood statements: Affective changes or demand characteristics?

Polivy, J., & Doyle, C. (1980) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.89.2.286 · Cited by 114 · see citing works

Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype

Tegeder, I., Adolph, J., Schmidt, H., Woolf, C. J., Geißlinger, G., & Lötsch, J. (2008) · European Journal of Pain · doi:10.1016/j.ejpain.2008.02.004 · Cited by 110 · see citing works

Psychiatric comorbidity in young heroin users

Rodríguez-Llera, M. C., Domingo‐Salvany, A., Brugal, M. T., Silva, T. C., Niubo, A. S., & Torrens, M. (2006) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2005.11.025 · Cited by 103 · see citing works

Abnormal pain response in pain-sensitive opiate addicts after prolonged abstinence predicts increased drug craving

Ren, Z.-Y., Shi, J., Epstein, D. H., Wang, J., & Lu, L. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1472-0 · Cited by 101 · see citing works

The submaximal effort tourniquet test: Its use in evaluating experimental and chronic pain

Moore, P. A., Duncan, G. H., Scott, D. S., Gregg, J. M., & Ghia, J. N. (1979) · Pain · doi:10.1016/0304-3959(79)90055-1 · Cited by 100 · see citing works

Illicit drug use and anxiety disorders: Findings from two community surveys

Sareen, J., Chartier, M., Paulus, M. P., & Stein, M. B. (2006) · Psychiatry Research · doi:10.1016/j.psychres.2006.01.009 · Cited by 97 · see citing works

Emotional modulation of pain: A clinical perspective

Klossika, I., Flor, H., Kamping, S., Bleichhardt, G. M., Trautmann, N., Treede, R., Bohus, M., & Schmahl, C. G. (2006) · Pain · doi:10.1016/j.pain.2006.08.007 · Cited by 88 · see citing works

Opiate modulating properties of nociceptin/orphanin FQ☆

Harrison, L. M., & Grandy, D. K. (2000) · Peptides · doi:10.1016/s0196-9781(99)00185-0 · Cited by 88 · see citing works

Cardiovascular and sensory responses to forearm ischemia and dynamic hand exercise

Maixner, W. D., Gracely, R. H., Zuniga, J. R., Humphrey, C., & Bloodworth, G. R. (1990) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1990.259.6.r1156 · Cited by 87 · see citing works

Affective associative learning modifies the sensory perception of nociceptive stimuli without participant's awareness

Wunsch, A., Philippot, P., & Plaghki, L. (2003) · Pain · doi:10.1016/s0304-3959(02)00331-7 · Cited by 66 · see citing works

Shock-induced hyperalgesia: III. Role of the bed nucleus of the stria terminalis and amygdaloid nuclei.

Crown, E. D., King, T. E., Meagher, M. W., & Grau, J. W. (2000) · Behavioral Neuroscience · doi:10.1037/0735-7044.114.3.561 · Cited by 65 · see citing works

Current evidence for a modulation of nociception by human genetic polymorphisms

Lötsch, J., & Geißlinger, G. (2007) · Pain · doi:10.1016/j.pain.2007.06.024 · Cited by 58 · see citing works

Is Humor Only Fun, An Alternative Cure or Magic? The Cognitive Therapeutic Potential of Humor

Gelkopf, M., & Kreitler, S. (1996) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.10.4.235 · Cited by 48 · see citing works

Mécanismes cérébraux impliqués dans l’interaction entre la douleur et les émotions

Duquette, M., Roy, M., Leporé, F., Peretz, I., & Rainville, P. (2007) · Revue Neurologique · doi:10.1016/s0035-3787(07)90388-4 · Cited by 45 · see citing works

Opioid-induced hyperalgesia—Pathophysiology and clinical relevance

Koppert, W. (2007) · Acute Pain · doi:10.1016/j.acpain.2006.11.001 · Cited by 41 · see citing works

A family-based investigation of cold pain tolerance

Birklein, F., Depmeier, C., Rolke, R., Hansen, C., Rautenstrauss, B. W., Prawitt, D., & Magerl, W. (2008) · Pain · doi:10.1016/j.pain.2007.11.012 · Cited by 40 · see citing works

The Relationship of Stress, Coping, Effect Expectancies and Craving

Grüsser, S. M., Mörsen, C. P., Wölfling, K., & Flor, H. (2006) · European Addiction Research · doi:10.1159/000095813 · Cited by 38 · see citing works

High-risk relapse situations and self-efficacy: Comparison between alcoholics and heroin addicts

El, G. E. S., & Bashir, T. Z. (2004) · Addictive Behaviors · doi:10.1016/j.addbeh.2004.02.003 · Cited by 37 · see citing works

Individual Differences in Emotional Processing and Reactivity to Pain Among Older Women With Rheumatoid Arthritis

Hamilton, N. A., Zautra, A., & Reich, J. W. (2007) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e31802b4f58 · Cited by 37 · see citing works

Tolerance, opioid-induced allodynia and withdrawal associated allodynia in infant and young rats

Zissen, M. H., Zhang, G., McKelvy, A. D., Propst, J. T., Kendig, J. J., & Sweitzer, S. M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.078 · Cited by 34 · see citing works

Comparison of subjective and objective analgesic effects of intravenous and intrathecal morphine in chronic pain patients by heat beam dolorimetry

Lipman, J. J., & Blumenkopf, B. (1989) · Pain · doi:10.1016/0304-3959(89)90037-7 · Cited by 33 · see citing works

Mechanical allodynia and thermal hyperalgesia upon acute opioid withdrawal in the neonatal rat

Sweitzer, S. M., Allen, C. P., Zissen, M. H., & Kendig, J. J. (2004) · Pain · doi:10.1016/j.pain.2004.04.003 · Cited by 31 · see citing works

Affective Modulation of Pain in Substance-Dependent Veterans

Rhudy, J. L., Dubbert, P. M., Parker, J. D., Burke, R. S., & Williams, A. E. (2006) · Pain Medicine · doi:10.1111/j.1526-4637.2006.00237.x · Cited by 30 · see citing works

Endogenous pain facilitory systems Antianalgesia and hyperalgesia

Maier, S. F., Wiertelak, E. P., & Watkins, L. R. (1992) · APS Journal · doi:10.1016/1058-9139(92)90009-2 · Cited by 30 · see citing works

Pain sensitivity in former opioid addicts

Liebmann, P. M., Lehofer, M., Schönauer-Cejpek, M., Legl, T., Pernhaupt, G., Moser, M., & Schauenstein, K. (1994) · The Lancet · doi:10.1016/s0140-6736(94)91697-7 · Cited by 27 · see citing works

Nervousness and pain sensitivity: II. Changed relation in ex-addicts as a predictor for early relapse

Liebmann, P. M., Lehofer, M., Moser, M., Legl, T., Pernhaupt, G., & Schauenstein, K. (1998) · Psychiatry Research · doi:10.1016/s0165-1781(98)00024-9 · Cited by 21 · see citing works

Opioid use disorder

Strang, J., Volkow, N. D., Degenhardt, L., Hickman, M., Johnson, K., Koob, G. F., Marshall, B. D. L., Tyndall, M., & Walsh, S. L. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0137-5 · Cited by 639 · see citing works

Neurobiology of opioid addiction: Opponent process, hyperkatifeia, and negative reinforcement

Koob, G. F. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.05.023 · Cited by 477 · see citing works

Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development

Koob, G. F. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000083 · Cited by 337 · see citing works

Chronic Opioid Therapy and Central Sensitization in Sickle Cell Disease

Carroll, C. P., Lanzkron, S., Haywood, C., Kiley, K. B., Pejsa, M., Moscou-Jackson, G., Haythornthwaite, J. A., & Campbell, C. M. (2016) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2016.02.012 · Cited by 92 · see citing works

Cues conditioned to withdrawal and negative reinforcement: Neglected but key motivational elements driving opioid addiction

Pantazis, C. B., Gonzalez, L. A., Tunstall, B. J., Carmack, S. A., Koob, G. F., & Vendruscolo, L. F. (2021) · Science Advances · doi:10.1126/sciadv.abf0364 · Cited by 73 · see citing works

Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats

Kimbrough, A., Kononoff, J., Simpson, S., Kallupi, M., Sedighim, S., Palomino, K., Conlisk, D., Momper, J. D., de Guglielmo, G., & George, O. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05479-y · Cited by 62 · see citing works

Heroin and its metabolites: relevance to heroin use disorder

Milella, M. S., D’Ottavio, G., Pirro, S. D., Barra, M., Caprioli, D., & Badiani, A. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02406-5 · Cited by 59 · see citing works

The affective dimension of pain as a risk factor for drug and alcohol addiction

LeBlanc, D. M., McGinn, M. A., Itoga, C. A., & Edwards, S. (2015) · Alcohol · doi:10.1016/j.alcohol.2015.04.005 · Cited by 44 · see citing works

Divergent profiles of fentanyl withdrawal and associated pain in mice and rats

Uddin, O., Jenne, C. E., Fox, M. E., Arakawa, K., Keller, A., & Cramer, N. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.173077 · Cited by 44 · see citing works

Neuronal Correlates of Hyperalgesia and Somatic Signs of Heroin Withdrawal in Male and Female Mice

Álvarez-Bagnarol, Y., Marchette, R. C. N., Francis, C., Morales, M., & Vendruscolo, L. F. (2022) · eNeuro · doi:10.1523/eneuro.0106-22.2022 · Cited by 33 · see citing works

κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats

Marchette, R. C. N., Gregory‐Flores, A., Tunstall, B. J., Carlson, E. R., Jackson, S. N., Sulima, A., Rice, K. C., Koob, G. F., & Vendruscolo, L. F. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100325 · Cited by 31 · see citing works

Complex Persistent Opioid Dependence—an Opioid-induced Chronic Pain Syndrome

Manhapra, A. (2022) · Current Treatment Options in Oncology · doi:10.1007/s11864-022-00985-x · Cited by 31 · see citing works

Spinal ephrin B / EphB signalling contributed to remifentanil‐induced hyperalgesia via NMDA receptor

Xia, W. S., Peng, Y., Tang, L., Jiang, L., Yu, L., Zhou, X., Zhang, F. J., & Yan, M. (2014) · European Journal of Pain · doi:10.1002/j.1532-2149.2014.00478.x · Cited by 27 · see citing works

Demographic and clinical factors predicting retention in methadone maintenance: results from an Irish cohort

Darker, C. D., Ho, J., Kelly, G., Whiston, L., & Barry, J. (2015) · Irish Journal of Medical Science (1971 -) · doi:10.1007/s11845-015-1314-5 · Cited by 25 · see citing works

Pharmacotherapeutic management of co-morbid alcohol and opioid use

Hood, L. E., Leyrer‐Jackson, J. M., & Olive, M. F. (2020) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2020.1732349 · Cited by 25 · see citing works

Withdrawal-associated injury site pain (WISP): a descriptive case series of an opioid cessation phenomenon

Rieb, L. M., Norman, W. V., Martin, R. E., Berkowitz, J., Wood, E., McNeil, R., & Milloy, M. (2016) · Pain · doi:10.1097/j.pain.0000000000000710 · Cited by 22 · see citing works

The Convergent Neuroscience of Affective Pain and Substance Use Disorder

Pahng, A. R. (2021) · Alcohol research · doi:10.35946/arcr.v41.1.14 · Cited by 23 · see citing works

Sex Differences in Regional Brain Glucose Metabolism Following Opioid Withdrawal and Replacement

Santoro, G. C., Carrión, J., Patel, K. J., Vilchez, C., Veith, J., Brodie, J. D., & Dewey, S. L. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.69 · Cited by 22 · see citing works

Extended access to fentanyl vapor self-administration leads to addiction-like behaviors in mice: Blood chemokine/cytokine levels as potential biomarkers

Marchette, R. C. N., Carlson, E. R., Said, N., Koob, G. F., & Vendruscolo, L. F. (2022) · Addiction Neuroscience · doi:10.1016/j.addicn.2022.100057 · Cited by 18 · see citing works

Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats

Kuhn, B. N., Cannella, N., Chitre, A. S., Nguyen, K., Cohen, K. A., Chen, D., Peng, B. F., Ziegler, K. S., Lin, B., Johnson, B. B., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02922-4 · Cited by 17 · see citing works

Mechanisms and Clinical Features of Co-Occurring Opioid and Nicotine Use

Lichenstein, S. D., Zakiniaeiz, Y., Yip, S. W., & Garrison, K. A. (2019) · Current Addiction Reports · doi:10.1007/s40429-019-00245-3 · Cited by 16 · see citing works

Protracted abstinence in males with an opioid use disorder: partial recovery of nucleus accumbens function

Tolomeo, S., Baldacchino, A., Volkow, N. D., & Steele, J. D. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01813-4 · Cited by 16 · see citing works

Opioid-driven disruption of the septal complex reveals a role for neurotensin-expressing neurons in withdrawal

Simon, R. C., Fleming, W., Briones, B. A., Trzeciak, M., Senthilkumar, P., Ishii, K. K., Hjort, M. M., Martin, M. M., Hashikawa, K., Sanders, A. D., et al. (2024) · Neuron · doi:10.1016/j.neuron.2025.04.024 · Cited by 24 · see citing works

A conceptual framework for the intersection of hyperalgesia and hyperkatifeia in alcohol addiction

Koob, G. F., & Vendruscolo, L. F. (2025) · Alcohol · doi:10.1016/j.alcohol.2025.08.004 · Cited by 13 · see citing works

Neuropeptide and cytokine regulation of pain in the context of substance use disorders

Delery, E., & Edwards, S. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108153 · Cited by 12 · see citing works

Inhibition of dorsal raphe GABAergic neurons blocks hyperalgesia during heroin withdrawal

Álvarez-Bagnarol, Y., García, R., Vendruscolo, L. F., & Morales, M. (2023) · Neuropsychopharmacology · doi:10.1038/s41386-023-01620-5 · Cited by 12 · see citing works

Examining Relationships between Gender, Opioid Dependence, and Distress Tolerance among Patients in Substance Use Disorder Treatment

Tull, M. T., Edmonds, K. A., Forbes, C. N., Richmond, J. R., Rose, J. P., Anestis, M. D., & Gratz, K. L. (2020) · Substance Use & Misuse · doi:10.1080/10826084.2020.1741632 · Cited by 11 · see citing works

The Dynorphin/-Opioid Receptor System at the Interface of Hyperalgesia/Hyperkatifeia and Addiction

Marchette, R. C. N., Vendruscolo, L. F., & Koob, G. F. (2025) · Current Addiction Reports · doi:10.1007/s40429-025-00618-x · Cited by 13 · see citing works

Withdrawal catastrophizing scale: initial psychometric properties and implications for the study of opioid use disorder and hyperkatifeia

Hall, O. T., Vilensky, M. R., Teater, J. E., Bryan, C. J., Rood, K. M., Niedermier, J. A., Entrup, P., Gorka, S. M., King, A., Williams, D. A., et al. (2024) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2023.2298257 · Cited by 8 · see citing works

Decision-making, somatic markers and emotion processing in opiate users

Biernacki, K., Terrett, G., McLennan, S. N., Labuschagne, I., Morton, P., & Rendell, P. G. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4760-0 · Cited by 9 · see citing works

Modeling spontaneous opioid withdrawal in male and female outbred mice using traditional endpoints and hyperalgesia

Brewer, A. L., Lewis, C. C., Eggerman, L., Blokker, A., Burkland, J. A., Johnsen, M., & Quock, R. M. (2022) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000714 · Cited by 9 · see citing works

Opioid-driven disruption of the septal complex reveals a role for neurotensin-expressing neurons in withdrawalPreprint

Simon, R. C., Fleming, W., Senthilkumar, P., Briones, B. A., Ishii, K. K., Hjort, M. M., Martin, M. M., Hashikawa, K., Sanders, A. D., Golden, S. A., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.15.575766 · Cited by 9 · see citing works

Characterization and validation of a spontaneous acute and protracted oxycodone withdrawal model in male and female mice

Contreras, K. M., Buzzi, B., Vaughn, J., Caillaud, M., Altarifi, A., Olszewski, E., Walentiny, D. M., Beardsley, P. M., & Damaj, M. I. (2024) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2024.173795 · Cited by 8 · see citing works

Cold nociception as a measure of hyperalgesia during spontaneous heroin withdrawal in mice

Hastings, L., Frye, E. V., Carlson, E. R., Chuong, V., Matthews, A. N., Koob, G. F., Vendruscolo, L. F., & Marchette, R. C. N. (2023) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2023.173694 · Cited by 8 · see citing works

The long-term effects of repeated heroin vapor inhalation during adolescence on measures of nociception and anxiety-like behavior in adult Wistar rats

Gutierrez, A., Harvey, E. L., Creehan, K. M., & Taffe, M. A. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06267-6 · Cited by 8 · see citing works

Heroin-based crack induces hyperalgesia through β-arrestin 2 redistribution and phosphorylation of Erk1/2 and JNK in the periaqueductal gray area

Aberoumandi, S. M., Vousooghi, N., Tabrizi, B. A., & Karimi, P. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.01.023 · Cited by 7 · see citing works

Escalation of intravenous fentanyl self-administration and assessment of withdrawal behavior in male and female mice

Chen, Y., Xiao, T., & Kimbrough, A. (2024) · Psychopharmacology · doi:10.1007/s00213-024-06739-x · Cited by 7 · see citing works

Morphine Withdrawal-Induced Hyperalgesia in Models of Acute and Extended Withdrawal Is Attenuated by l-Tetrahydropalmatine

Oleinichenko, D., Ahn, S., Song, R., Snutch, T. P., & Phillips, A. G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24108872 · Cited by 5 · see citing works

Predictors of concurrent heroin use among patients on opioid maintenance treatment in France: a multilevel study over 11 years

Janssen, É., Vuolo, M., Spilka, S., & Airagnes, G. (2024) · Harm Reduction Journal · doi:10.1186/s12954-024-00934-x · Cited by 5 · see citing works

Hyperbaric oxygen treatment attenuates naloxone-precipitated opioid withdrawal behaviors and alters microglial activity in male and female mice

Southard, M. T., Giannotti, G., Thakar, A., Willsey, T. R., Bailey, L. G., Salazar, F., Hentges, S. T., Quock, R. M., & Brown, T. E. (2025) · Scientific Reports · doi:10.1038/s41598-025-07937-z · Cited by 3 · see citing works

The relationship of pain intensity and opioid craving with delayed methadone dose: A preliminary study of individuals with opioid use disorder

MacLean, R. R., Spinola, S., Pittman, B. P., Meyerovich, J., Szollosy, S. K., Wolkowicz, N. R., Minnix, S., & Sofuoglu, M. (2024) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.16027 · Cited by 3 · see citing works

Pain in the management of opioid use disorder

SIROHI, S. K., & Tiwari, A. K. (2016) · Journal of Pain Research · doi:10.2147/jpr.s123667 · Cited by 3 · see citing works

Distinct Amygdala Neuronal Populations Control Opioid Use and Withdrawal in Mice

Tortorelli, L. S., Oo, H. Z., Hahn, S., Álvarez-Bagnarol, Y., Carrasquillo, Y., & Vendruscolo, L. F. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.08.021 · Cited by 3 · see citing works

Nonpharmacological and pharmacological influences on opioid effects: A review of clinical research findings

Luba, R. R., & Comer, S. D. (2025) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/j.jpet.2025.103709 · Cited by 2 · see citing works

Opioids

Koob, G. F., Arends, M. A., McCracken, M. L., & Moal, M. L. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-816988-9.00001-1 · Cited by 2 · see citing works

Associations of Interpersonal Trauma, Distress Intolerance, and Posttraumatic Stress Symptoms With Recent Problem Opioid Use in a Non-Clinical Sample of Women

Cole, J., & Logan, T. (2024) · Journal of Drug Issues · doi:10.1177/00220426241252336 · Cited by 1 · see citing works

Cannabinoids in Opioid Addiction Treatment: Pharmacological Mechanisms

Zuo, Q., Tam, K. L., Bekker, A., Zuo, W., & Ye, J.-H. (2019) · doi:10.35248/2329-6488.19.7.325 · Cited by 1 · see citing works

Fentanyl exposure during preconception and gestation permanently dysregulates endogenous opioid peptides and sympathoadrenal-medullary axis in the offspring

Ahmed, N., Dalmasso, C., Tavakoli, N. S., Abed, P. P., Turner, M. B., Czuba, L. C., Pautassi, R. M., Ortinski, P. I., & Loria, A. S. (2025) · Clinical Science · doi:10.1042/cs20256962

Glucocorticoid receptor blockade reverses heroin and alcohol withdrawal-induced hyperalgesia in rats

Skandan, N., Acosta, V., Vendruscolo, J. C. M., McGinn, M. A., & Vendruscolo, L. F. (2026) · Neuropharmacology · doi:10.1016/j.neuropharm.2026.110896

Addiction-Like Severity Predicts Prolonged Oxycodone Withdrawal-Induced Allodynia in Genetically Diverse RatsPreprint

Plasil, S. L., Tieu, L., Qian, C., Taylor, N., Sneddon, E. A., Carrette, L. L. G., Brennan, M., Morgan, A., Othman, D. N., Bai, K., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.14.725258

Drug-opposite neuroadaptation and breakthrough pain

Ballantyne, J. C., & Koob, G. F. (2026) · Journal of Pain · doi:10.1016/j.jpain.2026.106394

Addiction-like behavioral severity predicts prolonged oxycodone withdrawal-induced allodynia in genetically diverse rats

Plasil, S. L., Tieu, L., Qian, C., Taylor, N., Coe, S., Sneddon, E. A., Carrette, L. L. G., Brennan, M., Morgan, A. A., Othman, D. N., et al. (2026) · Neuropharmacology · doi:10.1016/j.neuropharm.2026.111197

Negative affect heightens opiate withdrawal-induced hyperalgesia in heroin abusers

Carcoba, L. M. (2013)

Dysregulation of emotional response in current and abstinent heroin users: negative heightening and positive blunting

de Arcos, F. A., Verdejo‐García, A., Ceverino, A., Pareja, M. M., López-Juárez, E., Sánchez-Barrera, M. B., Jiménez, Á. L., Pérez-Garcı́a, M., & Pepsa team (2008) · Psychopharmacology · doi:10.1007/s00213-008-1110-2 · Cited by 83 · see citing works

Increased pain sensitivity in alcohol withdrawal syndrome

Jochum, T., Boettger, M. K., Burkhardt, C., Juckel, G., & Bär, K. (2010) · European Journal of Pain · doi:10.1016/j.ejpain.2009.11.008 · Cited by 128 · see citing works

Withdrawal hyperalgesia after acute opioid physical dependence in nonaddicted humans: a preliminary study

Compton, P., Athanasos, P., & Elashoff, D. (2003) · The Journal of Pain · doi:10.1016/j.jpain.2003.08.003 · Cited by 138 · see citing works

Acute effects of heroin on emotions in heroin‐dependent patients

Blum, J., Gerber, H., Gerhard, U., Schmid, O., Petitjean, S. A., Riecher‐Rössler, A., Wiesbeck, G. A., Borgwardt, S., & Walter, M. (2013) · American Journal on Addictions · doi:10.1111/j.1521-0391.2013.12025.x · Cited by 45 · see citing works