Positive Affect as a Predictor of Smoking Cessation and Relapse: Does It Offer Unique Predictive Value among Depressive Symptom Domains?
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BACKGROUND: Prior studies have suggested that, among the domains of depressive symptoms, low positive affect (PA) may have a distinct relationship with smoking cessation and relapse. However, the empirical basis for PA-focused interventions cessation is limited, with some mixed findings. OBJECTIVES: Using a large, diverse sample of treatment-seeking smokers, this study tested the hypothesis that PA adds unique predictive value beyond the effects of the other symptom domains in models of cessation and relapse. METHODS: Adult smokers participating in a smoking cessation trial (n = 450) were included in this post hoc analysis. Cessation outcomes included smoking abstinence at end of treatment and at 6-month follow-up. Relapse was defined as recurrence of smoking at 6-month follow-up among the end-of-treatment abstainers. Depressive symptoms were assessed at baseline using the Center for Epidemiologic Studies-Depression (CES-D) scale. RESULTS: With the exception of PA, all of the CES-D domains predicted reduced likelihood of smoking abstinence at end of treatment and cotinine-confirmed (but not self-reported) abstinence at 6 months, as did total CES-D score (all p-values < .05). None of the symptom domains predicted relapse. Conclusions/Importance: Our results provide further evidence that current depressive symptoms predict worse cessation outcomes, but they fail to support recent work suggesting that low PA has incremental predictive value for cessation or relapse beyond the other depressive symptom domains. To improve quit rates for smokers with depressive symptoms, evidence-based mood management interventions should be included in treatment planning.
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Previous work found greater discrepancy between self-reported and cotinine-confirmed abstinence among individuals with depressive symptoms.
“our previous work demonstrated greater discrepancy between self-reported and cotinine-confirmed smoking abstinence among individuals with depressive symptoms (Heffner et al., 2017)”
From Smokers with bipolar disorder, other affective disorders, and no mental health conditions: Comparison of baseline characteristics and success at quitting in a large 12-month behavioral intervention randomized trial. (2018) · cites this paper as Heffner et al., 2017
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Heffner, J. L., Kelly, M. M., Waxmonsky, J., Mattocks, K., Serfozo, E., Bricker, J. B., Mull, K. E., Watson, N. L., & Ostacher, M. (2020) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntz242 · Cited by 39 · see citing works
Self-citationHeffner, J. L., Mull, K. E., Watson, N. L., McClure, J. B., & Bricker, J. B. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.08.034 · Cited by 11 · see citing works
Self-citationHeffner, J. L., Watson, N. L., Serfozo, E., Mull, K. E., MacPherson, L., Gasser, M., & Bricker, J. B. (2019) · JMIR Formative Research · doi:10.2196/13728 · Cited by 10 · see citing works
Self-citation
- Authors
- Heffner, J. L., Mull, K. E., McClure, J. B., & Bricker, J. B.
- Affiliations
- Fred Hutch Cancer Center (US)
- Kaiser Permanente Washington Health Research Institute (US)
- University of Washington (US)
- Corresponding author
- Heffner, Jaimee L.
- Venue
- Substance Use & Misuse
- Publisher
- Informa UK Limited
- Published
- 2017-11-21
- Volume
- 53
- Issue
- 6
- Pages
- 980-988
- ISSN
- 1082-6084 (ISSN-L)
- 1532-2491
- PMC
- PMC6159215
- OpenAlex
- W2770338146
- Cited by
- 16
- References
- 6
- Citations by year
- 2024: 2 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 4
- FWCI
- 1.75
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Substance Use & Misuse (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- GlaxoSmithKline
- Kaiser Permanente
- National Institutes of Health
- National Cancer Institute (R01CA151251)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- positive affect, smoking cessation, smoking relapse, depressive symptoms, smoking abstinence, treatment-seeking smokers, CES-D
- MeSH terms
- Affect, Depression, Female, Humans, Male, Middle Aged, Recurrence, Smoking Cessation, Secondary Prevention
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