Psychiatric disorders in smokers seeking treatment for tobacco dependence: Relations with tobacco dependence and cessation.
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OBJECTIVE: The present research examined the relation of psychiatric disorders to tobacco dependence and cessation outcomes. METHOD: Data were collected from 1,504 smokers (58.2% women; 83.9% White; mean age = 44.67 years, SD = 11.08) making an aided smoking cessation attempt as part of a clinical trial. Psychiatric diagnoses were determined with the Composite International Diagnostic Interview structured clinical interview. Tobacco dependence was assessed with the Fagerström Test of Nicotine Dependence (FTND) and the Wisconsin Inventory of Smoking Dependence Motives (WISDM). RESULTS: Diagnostic groups included those who were never diagnosed, those who had ever been diagnosed (at any time, including in the past year), and those with past-year diagnoses (with or without prior diagnosis). Some diagnostic groups had lower follow-up abstinence rates than did the never diagnosed group (ps < .05). At 8 weeks after quitting, strong associations were found between cessation outcome and both past-year mood disorder and ever diagnosed anxiety disorder. At 6 months after quitting, those ever diagnosed with an anxiety disorder (OR = .72, p = .02) and those ever diagnosed with more than one psychiatric diagnosis (OR = .74, p = .03) had lower abstinence rates. The diagnostic categories did not differ in smoking heaviness or the FTND, but they did differ in dependence motives assessed with the WISDM. CONCLUSION: Information on recent or lifetime psychiatric disorders may help clinicians gauge relapse risk and may suggest dependence motives that are particularly relevant to affected patients. These findings also illustrate the importance of using multidimensional tobacco dependence assessments.
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The independent contribution of each disorder (depression and anxiety) to smoking cessation remains unclear.
“Additionally, given the high comorbidity between depression and anxiety [19], the independent contribution of each disorder to smoking cessation remains unclear [11,20,21].”
From Acceptance and Commitment Therapy Wellness Program for Latine Adults Who Smoke and Have Psychological Distress: Protocol for a Feasibility Study (2023) · cites this paper as [11]
The Results > Cessation Outcomes section directly examines the disorders’ relative effects in a model including mood and anxiety diagnoses. It reports that anxiety independently predicted poorer abstinence at both follow-ups, while mood disorder was not a significant predictor in that model, rather than leaving their independent contributions unexamined. (LLM, conf=0.85)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredDepression and anxiety place smokers at increased risk for cessation failure, though some studies suggest the evidence is inconclusive.
“Considerable research has assessed the impact of depression and anxiety on cessation outcomes, with a number of studies reporting that depression and anxiety place smokers at increased risk for cessation failure [9-14], with other studies suggesting that the evidence is inconclusive [6,15-18].”
From Acceptance and Commitment Therapy Wellness Program for Latine Adults Who Smoke and Have Psychological Distress: Protocol for a Feasibility Study (2023) · cites this paper as [11]
Anxiety and depressive pathology significantly impair cessation success.
“anxiety and depressive pathology significantly impair cessation success (Piper et al., 2010; Zvolensky et al., 2008; Leventhal & Zvolensky, 2015; Piper et al., 2011).”
From A qualitative study of the feasibility and acceptability of a smoking cessation program for people living with HIV and emotional dysregulation. (2019) · cites this paper as Piper et al., 2010
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- Authors
- Piper, M. E., Smith, S. S., Schlam, T. R., Fleming, M. F., Bittrich, A. A., Brown, J. L., Leitzke, C. J., Zehner, M. E., Fiore, M. C., & Baker, T. B.
- Affiliations
- University of Wisconsin–Madison (US)
- ORCID
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2010-02
- Volume
- 78
- Issue
- 1
- Pages
- 13-23
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC2813467
- OpenAlex
- W2094429523
- Cited by
- 150
- References
- 79
- Citations by year
- 2025: 1 · 2024: 8 · 2023: 9 · 2022: 4 · 2021: 4 · 2020: 8 · 2019: 7 · 2018: 10 · 2017: 8 · 2016: 14 · 2015: 16 · 2014: 16 · 2013: 10 · 2012: 19
- FWCI
- 9.53
- Type
- journal article
- Language
- en
- Update notices
- correction (2017-08-31)
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (P50 DA019706, M01 RR03186)
- University of Wisconsin—Madison (1KL2RR025012-01)
- National Cancer Institute (1K05CA139871)
- GlaxoSmithKline
- Elan Corporation, plc.
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Keywords
- mental illness, tobacco dependence, smoking cessation, mood disorders, anxiety disorders, abstinence rates, relapse risk, smoking heaviness
- MeSH terms
- Adult, Anxiety Disorders, Double-Blind Method, Female, Humans, Male, Middle Aged, Motivation, Nicotine, Psychiatric Status Rating Scales, Surveys and Questionnaires, Regression Analysis, Smoking, Tobacco Use Disorder, Smoking Cessation, Treatment Outcome, Patient Selection, Mood Disorders
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