The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Burden, depression, and anxiety in caregivers of people with amyotrophic lateral sclerosis
Abstract
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease caused by the degeneration of motor neurons. The burden for ALS caregivers is quite high. There are still few studies that have investigated the emotional impact of ALS care. We conducted a cross-sectional study among 40 ALS caregivers, assessing general worries, burden of care, depression, anxiety, perception of social support, and patients' severity of disease. Caregiver burden, depression, and anxiety were positively related with each other, and all these variables had a negative relation with social support. Patient's loss of physical functions was positively related with caregiver burden, anxiety, and somatic expression of depression. Caregivers expressed worries for their own health conditions. Given these results, we consider the hypothesis of an emotional-somatic impact of ALS care. The implications and limitations are discussed.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Previous research has shown that psychological distress and feelings of burden of ALS caregivers are associated with disease characteristics of the patient (i.e. physical and behavioral problems) but also with characteristics of the caregivers themselves, such as their coping style or whether they find positive meaning in caregiving [7, 9, 11–15].”
In the citing paper
“This effect is consistent with research of burden over time in MND family carers [15-17].”
From Feasibility, acceptability and potential effectiveness of dignity therapy for family carers of people with motor neurone disease (2014) · cites this paper as [15]
In the citing paper
“Moreover, carer burden increases in MND family carers over time as patient function declines [15-17].”
From Feasibility, acceptability and potential effectiveness of dignity therapy for family carers of people with motor neurone disease (2014) · cites this paper as [15]
Citations
Cites
(1970) · Cited by 24,983
Relatives of the Impaired Elderly: Correlates of Feelings of Burden
Zarit, S. H., Reever, K. E., & Bach-Peterson, J. (1980) · The Gerontologist · doi:10.1093/geront/20.6.649 · Cited by 5,810
El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis
Brooks, B. R., Miller, R. G., Swash, M., & Munsat, T. L. (2000) · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders · doi:10.1080/146608200300079536 · Cited by 5,433
Cedarbaum, J. M., Stambler, N., Malta, E., Fuller, C., Hilt, D., Thurmond, B., & Nakanishi, A. (1999) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(99)00210-5 · Cited by 3,307
(2018) · فصلنامه علمی پژوهشی توانبخشی · doi:10.21859/jrehab · Cited by 1,975
Cohen, S. R., Mount, B. M., Strobel, M. G., & Bui, F. (1995) · Palliative Medicine · doi:10.1177/026921639500900306 · Cited by 737
Haverkamp, L. J., Appel, V., & Appel, S. H. (1995) · Brain · doi:10.1093/brain/118.3.707 · Cited by 697
Resilience and Distress Among Amyotrophic Lateral Sclerosis Patients and Caregivers
Rabkin, J. G., Wagner, G. J., & Del Bene, M. (2000) · Psychosomatic Medicine · doi:10.1097/00006842-200003000-00020 · Cited by 288
A longitudinal study on quality of life and depression in ALS patient–caregiver couples
Gauthier, A., Vignola, A., Calvo, A., Cavallo, E., Moglia, C., Sellitti, L., Mutani, R., & Chiò, A. (2007) · Neurology · doi:10.1212/01.wnl.0000257093.53430.a8 · Cited by 256
Caregiver burden and patients’ perception of being a burden in ALS
Chiò, A., Gauthier, A., Calvo, A., Ghiglione, P., & Mutani, R. (2005) · Neurology · doi:10.1212/01.wnl.0000162034.06268.37 · Cited by 223
A cross sectional study on determinants of quality of life in ALS
Chio, A. (2004) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2003.033100 · Cited by 190
Subjective experience and coping in ALS
Hecht, M. J., Hillemacher, T., Gräsel, E., Tigges, S., Winterholler, M., Heuß, D. F., Hilz, M. J., & Neundörfer, B. (2002) · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders · doi:10.1080/146608202760839009 · Cited by 147
The natural history of motoneuron loss in amyotrophic lateral sclerosis
Munsat, T. L., Andres, P. L., Finison, L. J., Conlon, T., & Thibodeau, L. (1988) · Neurology · doi:10.1212/wnl.38.3.409 · Cited by 146
GOLDSTEIN, L. H., ATKINS, L., LANDAU, S., BROWN, R., & LEIGH, P. N. (2006) · Psychological Medicine · doi:10.1017/s0033291706007124 · Cited by 123
Home care of patients with amyotrophic lateral sclerosis (ALS)
Krivickas, L. S., Shockley, L., & Mitsumoto, H. (1997) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(97)00251-7 · Cited by 118
Burden of care in amyotrophic lateral sclerosis
Hecht, M. J., Graesel, E., Tigges, S., Hillemacher, T., Winterholler, M., Hilz, M. J., Heuß, D. F., & Neundörfer, B. (2003) · Palliative Medicine · doi:10.1191/0269216303pm754oa · Cited by 108
Coco, G. L., Coco, D. L., Cicero, V., Oliveri, A. M., Verso, G. L., Piccoli, F., & Bella, V. L. (2005) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2005.05.018 · Cited by 96
Anxiety undermines quality of life in ALS patients and caregivers
Vignola, A., Guzzo, A., Calvo, A., Moglia, C., Pessia, A., Cavallo, E., Cammarosano, S., Giacone, S., Ghiglione, P., & Chiò, A. (2008) · European Journal of Neurology · doi:10.1111/j.1468-1331.2008.02303.x · Cited by 89
Interviews with Patients, Family, and Caregivers in Amyotrophic Lateral Sclerosis: Comparing Needs
Bolmsjö, I., & Hermerén, G. (2001) · Journal of Palliative Care · doi:10.1177/082585970101700403 · Cited by 80
Caregiver distress in parkinsonism
Cifu, D. X., Carne, W. F., Brown, R., Pegg, P. O., Ong, J. C., Qutubuddin, A. A., & Baron, M. S. (2006) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2005.08.1365 · Cited by 67
The Impact of Neurological Illness on Marital Relationships
O’Connor, E. J., McCabe, M. P., & Firth, L. A. (2008) · Journal of Sex & Marital Therapy · doi:10.1080/00926230701636189 · Cited by 64
Care for Caregivers: The Needs of Family Members of MS Patients
Cockerill, R. W., & Warren, S. (1990) · Journal of rehabilitation · Cited by 35
Illness experience in a chronic disease - ALS
Cobb, A. K., & Hamera, E. (1986) · Social Science & Medicine · doi:10.1016/0277-9536(86)90111-5 · Cited by 26
Cited by
Sorted by citations
Clinical diagnosis and management of amyotrophic lateral sclerosis
Hardiman, O. M., van den Berg, L. H., & Kiernan, M. C. (2011) · Nature Reviews Neurology · doi:10.1038/nrneurol.2011.153 · Cited by 618
del-Pino-Casado, R., Priego-Cubero, E., López-Martínez, C., & Orgeta, V. (2021) · PLOS ONE · doi:10.1371/journal.pone.0247143 · Cited by 331
“, 2010 [86] 40 Cross-sectional Multiple sclerosis ZBI STAI Palacio et al.”
BackgroundThe cognitive profile of ALS: a systematic review and meta-analysis update
Beeldman, E., Raaphorst, J., Klein Twennaar, M., de Visser, M., Schmand, B. A., & de Haan, R. J. (2016) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2015-310734 · Cited by 313
Caregiver burden in amyotrophic lateral sclerosis: A systematic review
de Wit, J., Bakker, L. A., van Groenestijn, A. V., van den Berg, L. H., Schröder, C., Visser-Meily, J. A., & Beelen, A. (2017) · Palliative Medicine · doi:10.1177/0269216317709965 · Cited by 153
Lillo, P., Mioshi, E., & Hodges, J. R. (2012) · BMC Neurology · doi:10.1186/1471-2377-12-156 · Cited by 157
Metadata
- Authors
- Pagnini, F., Rossi, G., Lunetta, C., Banfi, P., Castelnuovo, G., Corbo, M., & Molinari, E.
- Affiliations
- Università Cattolica del Sacro Cuore (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Corresponding author
- Pagnini, Francesco
- ORCID
- Venue
- Psychology, Health & Medicine
- Publisher
- Informa UK Limited
- Published
- 2010-12
- Volume
- 15
- Issue
- 6
- Pages
- 685-693
- ISSN
- 1354-8506 (ISSN-L)
- 1465-3966
- OpenAlex
- W1985871185
- Cited by
- 139
- References
- 23
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 7 · 2023: 13 · 2022: 6 · 2021: 12 · 2020: 14 · 2019: 3 · 2018: 6 · 2017: 6 · 2016: 11 · 2015: 12 · 2014: 13 · 2013: 5 · 2012: 11
- FWCI
- 14.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychology Health & Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Research and Theory › Nursing care and research
- Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
- Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
- Keywords
- amyotrophic lateral sclerosis, caregiver burden, depression, anxiety, social support, emotional impact of caregiving, somatic symptoms of depression, disease severity
- MeSH terms
- Aged, Amyotrophic Lateral Sclerosis, Anxiety, Cross-Sectional Studies, Depression, Female, Humans, Italy, Male, Middle Aged, Surveys and Questionnaires, Caregivers, Cost of Illness
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
