Cited by 133Dementia and Cognitive Impairment ResearchNursing care and researchFamily Caregiving in Mental Illness

The DOI matches its Crossref record; 122 of the 123 references it cites were found in a registry or an index.

Alzheimers’ disease and caregiving: a meta-analytic review comparing the mental health of primary carers to controls

Ma, Mandy, Dorstyn, Diana, Ward, Lynn, Prentice, Shaun·2018·Aging & Mental Health

DOI 10.1080/13607863.2017.1370689

Open this paper in CoChat — free account

Abstract

Objectives To quantitatively review the literature comparing depressed mood, anxiety and psychological distress in caregivers (CGs) of older adults with Alzheimer's disease (AD) with non-caregivers (NCGs) Methods: Eighteen independent studies comparing AD CGs (N = 2378) with NCGs (N = 70,035) were evaluated in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Standardised mean differences (Hedges' g) with associated 95% confidence intervals and p-values were calculated using a random-effects model. Results Studies generally conformed to STROBE criteria in terms of their methodological and procedural detail, although data management issues that may contribute to methodological bias were identified. Pooled effect estimates revealed medium to large group differences in depression (g w = 1.01 [CI: 0.73, 1.29] p w = 0.64 [CI: 0.39, 0.89] p w = 1.58 [CI: 1.11, 2.05], p Discussion Caregivers of patients with AD experience poor mental health in comparison to the general population, with female caregivers being disproportionately affected. Further exploration of the psychosocial variables that contribute to these group differences is needed to inform effective support services and, in turn, help caregivers manage the emotional demands of AD.

Integrity signals

Registry

Crossref · 10.1080/13607863.2017.1370689

Cites

122 of 122 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
Stress, appraisal, and coping
Eysenck, H. J. (1985) · Behaviour Research and Therapy · doi:10.1016/0005-7967(85)90087-7 · Cited by 32,038
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS‐ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
“Stress: appraisal and coping,”
Folkman, S. (2013) · Encyclopedia of Behavioral Medicine · doi:10.1007/978-1-4419-1005-9_215 · Cited by 27,833
The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, F. T. S. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-8-200710160-00010 · Cited by 17,796
Introduction to Meta‐Analysis
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2009) · doi:10.1002/9780470743386 · Cited by 14,225
Introduction to Meta‐Analysis
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2021) · doi:10.1002/9781119558378 · Cited by 9,799
Untitled work
(2000) · Cited by 9,198
Caregiving and the stress process: an overview of concepts and their measures
Pearlin, L. I., Mullan, J. T., Semple, S. J., & Skaff, M. M. (1990) · The Gerontologist · doi:10.1093/geront/30.5.583 · Cited by 4,810
The Hopkins Symptom Checklist (HSCL): A self-report symptom inventory
Derogatis, L. R., Lipman, R. S., Rickels, K., Uhlenhuth, E. H., & Covi, L. (1974) · Behavioral Science · doi:10.1002/bs.3830190102 · Cited by 4,604
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria
Dubois, B., Feldman, H. H., Jacova, C., DeKosky, S. T., Barberger-Gateau, P., Cummings, J., Delacourte, A., Galasko, D., Gauthier, S., Jicha, G., et al. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70178-3 · Cited by 4,411
Assessing heterogeneity in meta-analysis: Q statistic or I² index?
Huedo-Medina, T. B., Sánchez-Meca, J., Marín-Martínez, F., & Botella, J. (2006) · Psychological Methods · doi:10.1037/1082-989x.11.2.193 · Cited by 4,256
Differences between caregivers and noncaregivers in psychological health and physical health: A meta-analysis.
Pinquart, M., & Sörensen, S. (2003) · Psychology and Aging · doi:10.1037/0882-7974.18.2.250 · Cited by 2,857
A Re-Evaluation of Random-Effects Meta-Analysis
Higgins, J. P. T., Thompson, S. G., & Spiegelhalter, D. J. (2009) · Journal of the Royal Statistical Society Series A: Statistics in Society · doi:10.1111/j.1467-985x.2008.00552.x · Cited by 2,569
A Fail-Safe N for Effect Size in Meta-Analysis
Orwin, R. G. (1983) · Journal of Educational Statistics · doi:10.2307/1164923 · Cited by 2,064
Case-finding instruments for depression: Two questions are as good as many
Whooley, M. A., Avins, A. L., Miranda, J., & Browner, W. S. (1997) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.1997.00076.x · Cited by 1,826
Psychiatric and Physical Morbidity Effects of Dementia Caregiving: Prevalence, Correlates, and Causes
Schulz, R., O'Brien, A. T., Bookwala, J., & Fleissner, K. (1995) · The Gerontologist · doi:10.1093/geront/35.6.771 · Cited by 1,765
Is caregiving hazardous to one’s physical health? A meta-analysis
Vitaliano, P. P., Zhang, J., & Scanlan, J. M. (2003) · Psychological Bulletin · doi:10.1037/0033-2909.129.6.946 · Cited by 1,734
Family caregivers of people with dementia
Brodaty, H., & Donkin, M. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.2/hbrodaty · Cited by 1,644
Inference by Eye: Confidence Intervals and How to Read Pictures of Data.
Cumming, G., & Finch, S. (2005) · American Psychologist · doi:10.1037/0003-066x.60.2.170 · Cited by 1,449
Behavioral and psychological symptoms of dementia
Cerejeira, J., Lagarto, L., & Mukaetova-Ladinska, E. B. (2012) · Frontiers in Neurology · doi:10.3389/fneur.2012.00073 · Cited by 1,425
Gender Differences in Caregiver Stressors, Social Resources, and Health: An Updated Meta-Analysis
Pinquart, M., & Sorensen, S. (2006) · The Journals of Gerontology Series B: Psychological Sciences and Social Sciences · doi:10.1093/geronb/61.1.p33 · Cited by 1,213
Associations of stressors and uplifts of caregiving with caregiver burden and depressive mood: a meta-analysis
Pinquart, M., & Sörensen, S. (2003) · The Journals of Gerontology: Series B · doi:10.1093/geronb/58.2.p112 · Cited by 1,108
Spouses, adult children, and children-in-law as caregivers of older adults: A meta-analytic comparison.
Pinquart, M., & Sörensen, S. (2011) · Psychology and Aging · doi:10.1037/a0021863 · Cited by 947
Direction and impact of language bias in meta-analyses of controlled trials: empirical study
Jüni, P., Holenstein, F., Sterne, J., Bartlett, C., & Egger, M. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.1.115 · Cited by 892
Ethnic Differences in Stressors, Resources, and Psychological Outcomes of Family Caregiving: A Meta-Analysis
Pinquart, M., & Sörensen, S. (2005) · The Gerontologist · doi:10.1093/geront/45.1.90 · Cited by 793
The WHO World Mental Health Surveys: Global Perspectives on the Epidemiology of Mental Disorders
Kessler, R. C., & Üstün, T. B. (2008) · Cited by 747
Psychiatric and Physical Morbidity Effects of Caregiving
Schulz, R., VISINTAINER, P. F., & Williamson, G. M. (1990) · Journal of Gerontology · doi:10.1093/geronj/45.5.p181 · Cited by 639
Chronic stress and immunity in family caregivers of Alzheimerʼs disease victims.
Kiecolt‐Glaser, J. K., Glaser, R., Shuttleworth, E. C., Dyer, C. S., Ogrocki, P. K., & Speicher, C. E. (1987) · Psychosomatic Medicine · doi:10.1097/00006842-198709000-00008 · Cited by 484
A Path Model of Chronic Stress, the Metabolic Syndrome, and Coronary Heart Disease
Vitaliano, P. P., Scanlan, J. M., Zhang, J., Savage, M. V., Hirsch, I. B., & Siegler, I. C. (2002) · Psychosomatic Medicine · doi:10.1097/00006842-200205000-00006 · Cited by 481
A systematic review of telehealth tools and interventions to support family caregivers
Chi, N.-C., & Demiris, G. (2015) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x14562734 · Cited by 409
Predictors of Depression and Life Satisfaction Among Spousal Caregivers in Hospice: Application of a Stress Process Model
Haley, W. E., LaMonde, L. A., Han, B., Burton-Chase, A. M., & Schonwetter, R. S. (2003) · Journal of Palliative Medicine · doi:10.1089/109662103764978461 · Cited by 402
Prevalence of Mental Health Disorders Among Caregivers of Patients With Alzheimer Disease
Sallim, A. B., Sayampanathan, A. A., Cuttilan, A., & Chun-Man Ho, R. (2015) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2015.09.007 · Cited by 396
Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome
Lam, B., Masellis, M., Freedman, M., Stuss, D. T., & Black, S. E. (2013) · Alzheimer's Research & Therapy · doi:10.1186/alzrt155 · Cited by 386
A 2-year longitudinal study of depression among Alzheimer's caregivers.
Schulz, R., & Williamson, G. M. (1991) · Psychology and Aging · doi:10.1037/0882-7974.6.4.569 · Cited by 361
Life stress, mood disturbance, and elevated interleukin-6 in healthy older women
Lutgendorf, S. K., Garand, L., Buckwalter, K. C., Reimer, T. T., Hong, S.-Y., & Lubaroff, D. M. (1999) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/54.9.m434 · Cited by 305
Hearing Their Voice: A Systematic Review of Dementia Family Caregivers’ Needs
McCabe, M., You, E., & Tatangelo, G. (2016) · The Gerontologist · doi:10.1093/geront/gnw078 · Cited by 300
Uses and misuses of the STROBE statement: bibliographic study
da Costa, B. R., Cevallos, M., Altman, D. G., Rutjes, A. W., & Egger, M. (2011) · BMJ Open · doi:10.1136/bmjopen-2010-000048 · Cited by 288
Differential features of burden between spouse and adult-child caregivers of patients with Alzheimer's disease: An exploratory comparative design
Conde‐Sala, J. L., Garre‐Olmo, J., Garriga, O. T., Franch, J. V., & Pousa, S. L. (2010) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2010.03.001 · Cited by 281
Chronic stress, social support, and persistent alterations in the natural killer cell response to cytokines in older adults.
Esterling, B. A., Kiecolt‐Glaser, J. K., Bodnar, J. C., & Glaser, R. (1994) · Health Psychology · doi:10.1037/0278-6133.13.4.291 · Cited by 220
Neuropeptide Y and natural killer cell activity: findings in depression and Alzheimer caregiver stress
Irwin, M., Brown, M., Patterson, T., Hauger, R., Mascovich, A., & Grant, I. (1991) · The FASEB Journal · doi:10.1096/fasebj.5.15.1743441 · Cited by 219
Accelerated risk of hypertensive blood pressure recordings among alzheimer caregivers
Shaw, W. S., Patterson, T. L., Ziegler, M. G., Dimsdale, J. E., Semple, S. J., & Grant, I. (1999) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(98)00084-1 · Cited by 211
Premorbid Relationship Satisfaction and Caregiver Burden in Dementia Caregivers
Steadman, P. L., Tremont, G. N., & Davis, J. D. (2007) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988706298624 · Cited by 202
Psychiatric disorders in spouse caregivers of care recipients with Alzheimer's disease and matched controls: A diathesis-stress model of psychopathology.
Russo, J. E., VITALIANO, P. P., Brewer, D. D., Katon, W. J., & al, E. (1995) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.104.1.197 · Cited by 200
Effect of Alzheimer caregiving stress and age on frailty markers interleukin-6, c-reactive protein, and d-dimer
von Känel, R., Dimsdale, J. E., Mills, P. J., Ancoli-Israel, S., Patterson, T. L., Mausbach, B. T., & Grant, I. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.9.963 · Cited by 196
Psychosocial Modulation of Cytokine-Induced Natural Killer Cell Activity in Older Adults
Esterling, B. A., Kiecolt‐Glaser, J. K., & Glaser, R. (1996) · Psychosomatic Medicine · doi:10.1097/00006842-199605000-00010 · Cited by 188
The Critical Role of Caregivers in Achieving Patient-Centered Care
Gillick, M. R. (2013) · JAMA · doi:10.1001/jama.2013.7310 · Cited by 171
Poor Sleep Is Associated with Higher Plasma Proinflammatory Cytokine Interleukin‐6 and Procoagulant Marker Fibrin D‐Dimer in Older Caregivers of People with Alzheimer's Disease
von Känel, R., Dimsdale, J. E., Ancoli‐Israel, S., Mills, P. J., Patterson, T. L., McKibbin, C. L., Archuleta, C., & Grant, I. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.00642.x · Cited by 170
Incidence of Depression and Anxiety in the Spouses of Patients With Dementia: A Naturalistic Cohort Study of Recorded Morbidity With a 6-Year Follow-Up
Joling, K. J., van Hout, H. P. J., Schellevis, F., van der Horst, H. E., Scheltens, P., Knol, D. L., & van Marwijk, H. (2010) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181bf9f0f · Cited by 162
Increased Framingham Coronary Heart Disease Risk Score in Dementia Caregivers Relative to Non-Caregiving Controls
von Känel, R., Mausbach, B. T., Patterson, T. L., Dimsdale, J. E., Aschbacher, K., Mills, P. J., Ziegler, M. G., Ancoli-Israel, S., & Grant, I. (2008) · Gerontology · doi:10.1159/000113649 · Cited by 160
The health of persons giving care to the demented elderly: A critical review of the literature
Baumgarten, M. (1989) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(89)90111-x · Cited by 146
Psychophysiological Mediators of Caregiver Stress and Differential Cognitive Decline.
VITALIANO, P. P., Echeverria, D., Yi, J. P., Phillips, P. E. M., Young, H. M., & Siegler, I. C. (2005) · Psychology and Aging · doi:10.1037/0882-7974.20.3.402 · Cited by 144
A Comparison of Psychosocial Outcomes in Elderly Alzheimer Caregivers and Noncaregivers
Mausbach, B. T., Chattillion, E. A., Roepke, S. K., Patterson, T. L., & Grant, I. (2013) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2012.10.001 · Cited by 142
The statistical recommendations of the American Psychological Association Publication Manual: Effect sizes, confidence intervals, and meta‐analysis
Cumming, G., Fidler, F. M., Kalinowski, P., & Lai, J. (2011) · Australian Journal of Psychology · doi:10.1111/j.1742-9536.2011.00037.x · Cited by 140
Diagnosing Alzheimer's dementia in Down syndrome: Problems and possible solutions
Mark, R. E. (2009) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2009.01.010 · Cited by 133
Coping and Depression in Alzheimer's Caregivers: Longitudinal Evidence of Stability
Powers, D. V., Gallagher-Thompson, D. E., & KRAEMER, H. C. (2002) · The Journals of Gerontology Series B · doi:10.1093/geronb/57.3.p205 · Cited by 130
Health-Related Quality of Life for Caregivers of Patients With Alzheimer Disease
Markowitz, J. S., Gutterman, E. M., Sadik, K., & Papadopoulos, G. (2003) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-200310000-00003 · Cited by 122
A review of the factors associated with the non-use of respite services by carers of people with dementia: implications for policy and practice
Phillipson, L., Jones, S. C., & Magee, C. (2013) · Health & Social Care in the Community · doi:10.1111/hsc.12036 · Cited by 118
Measuring dementia carers' unmet need for services - an exploratory mixed method study
Stirling, C., Andrews, S., Croft, T., Vickers, J. C., Turner, P. A., & Robinson, A. (2010) · BMC Health Services Research · doi:10.1186/1472-6963-10-122 · Cited by 114
Expanding the conceptualization of caregiver coping: the importance of relationship-focused coping strategies
Kramer, B. J. (1993) · Family Relations · doi:10.2307/585338 · Cited by 113
Help-Seeking for Dementia
Werner, P., Goldstein, D., Segel‐Karpas, D., Chan, L. C. K., & Lai, C. K. Y. (2014) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0000000000000065 · Cited by 113
Mental and Physical Health of Male Caregivers of a Spouse with Alzheimer's Disease
Fuller-Jonap, F., & Haley, W. E. (1995) · Journal of Aging and Health · doi:10.1177/089826439500700105 · Cited by 109
Depressed Mood Mediates Decline in Cognitive Processing Speed in Caregivers
VITALIANO, P. P., Zhang, J., Young, H. M., Caswell, L. W., Scanlan, J. M., & Echeverria, D. (2009) · The Gerontologist · doi:10.1093/geront/gnp004 · Cited by 99
High Degree of Heterogeneity in Alzheimer's Disease Progression Patterns
Komarova, N. L., & Thalhauser, C. J. (2011) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002251 · Cited by 97
Sleep and Biomarkers of Atherosclerosis in Elderly Alzheimer Caregivers and Controls
von Känel, R., Ancoli‐Israel, S., Dimsdale, J. E., Mills, P. J., Mausbach, B. T., Ziegler, M. G., Patterson, T. L., & Grant, I. (2009) · Gerontology · doi:10.1159/000264654 · Cited by 96
The Relationship Among Stress, Depression, Locus of Control, Irrational Beliefs, Social Support, and Health in Alzheimerʼs Disease Caregivers
McNaughton, M. E., Patterson, T. L., Smith, T. L., & Grant, I. (1995) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199502000-00003 · Cited by 91
Effects of depressive and anxious symptoms on norepinephrine and platelet P-selectin responses to acute psychological stress among elderly caregivers
Aschbacher, K., Mills, P. J., von Känel, R., Hong, S., Mausbach, B. T., Roepke, S. K., Dimsdale, J. E., Patterson, T. L., Ziegler, M. G., Ancoli‐Israel, S., et al. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2007.10.002 · Cited by 89
Long-Term Effects of Bereavement and Caregiver Intervention on Dementia Caregiver Depressive Symptoms
Haley, W. E., Bergman, E., Roth, D. L., McVie, T., Gaugler, J. E., & Mittelman, M. S. (2008) · The Gerontologist · doi:10.1093/geront/48.6.732 · Cited by 89
Alzheimer caregiver stress: Basal natural killer cell activity, pituitary-adrenal cortical function, and sympathetic tone
Irwin, M. R., Hauger, R. L., Patterson, T. L., Semple, S. J., Ziegler, M. G., & Grant, I. (1997) · Annals of Behavioral Medicine · doi:10.1007/bf02883324 · Cited by 88
Family functioning in the caregivers of patients with dementia
Heru, A. M., Ryan, C. E., & Iqbal, A. (2004) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1119 · Cited by 87
A Comparison of Marital Interaction Patterns Between Couples in Which the Husband Does or Does Not Have Alzheimer's Disease
Gallagher-Thompson, D. E., Canto, P. G. D., Jacob, T., & Thompson, L. W. (2001) · The Journals of Gerontology Series B · doi:10.1093/geronb/56.3.s140 · Cited by 87
Upsetting social interactions and distress among Alzheimer's disease family care‐givers: A replication and extension
Kiecolt‐Glaser, J. K., Dyer, C. S., & Shuttleworth, E. C. (1988) · American Journal of Community Psychology · doi:10.1007/bf00930895 · Cited by 84
Effects of Alzheimer Caregiving on Allostatic Load
Roepke, S. K., Mausbach, B. T., Patterson, T. L., von Känel, R., Ancoli‐Israel, S., Harmell, A. L., Dimsdale, J. E., Aschbacher, K., Mills, P. J., Ziegler, M. G., et al. (2010) · Journal of Health Psychology · doi:10.1177/1359105310369188 · Cited by 84
The effects of bereavement after family caregiving
Schulz, R., Newsom, J. T., Fleissner, K., DECAMP, A. R., & Nieboer, A. P. (1997) · Aging & Mental Health · doi:10.1080/13607869757173 · Cited by 83
Dependence and Caregiver Burden in Alzheimer’s Disease and Mild Cognitive Impairment
Gallagher, D., Mhaoláin, Á. N., Crosby, L., Ryan, D., Lacey, L. A., Coen, R. F., Walsh, C., Coakley, D., Walsh, J. B., Cunningham, C. J., et al. (2011) · American Journal of Alzheimer s Disease & Other Dementias® · doi:10.1177/1533317510394649 · Cited by 81
Psychological Distress, Caregiving, and Metabolic Variables
VITALIANO, P. P., Scanlan, J. M., Krenz, C., Schwartz, R. S., & Marcovina, S. M. (1996) · The Journals of Gerontology Series B · doi:10.1093/geronb/51b.5.p290 · Cited by 78
Weight changes in caregivers of Alzheimer's care recipients: Psychobehavioral predictors.
VITALIANO, P. P., Russo, J. E., Scanlan, J. M., & Greeno, C. G. (1996) · Psychology and Aging · doi:10.1037/0882-7974.11.1.155 · Cited by 76
Psychophysiological correlates of cognitive deficits in family caregivers of patients with Alzheimer Disease
Corrêa, M. S., Vedovelli, K., Giacobbo, B. L., de Souza, C. E. B., Ferrari, P., Argimon, I. I. D. L., Walz, J. C., Kapczinski, F. P., & Bromberg, E. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.11.052 · Cited by 73
A follow up study of depression in the carers of dementia sufferers: Table 1
Ballard, C. G., Eastwood, C., Gahir, M., & Wilcock, G. K. (1996) · BMJ · doi:10.1136/bmj.312.7036.947 · Cited by 71
Coping Processes and Hemostatic Reactivity to Acute Stress in Dementia Caregivers
Aschbacher, K., Patterson, T. L., von Känel, R., Dimsdale, J. E., Mills, P. J., Adler, K. A., Ancoli‐Israel, S., & Grant, I. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000188458.85597.bc · Cited by 66
Psychosocial stress moderates the relationship of cancer history with natural killer cell activity
VITALIANO, P. P., Scanlan, J. M., Ochs, H. D., Syrjala, K. L., Siegler, I. C., & Snyder, E. A. (1998) · Annals of Behavioral Medicine · doi:10.1007/bf02884961 · Cited by 64
Sleep in Spousal Alzheimer Caregivers: A Longitudinal Study with a Focus on the Effects of Major Patient Transitions on Sleep
von Känel, R., Mausbach, B. T., Ancoli‐Israel, S., Dimsdale, J. E., Mills, P. J., Patterson, T. L., Ziegler, M. G., Roepke, S. K., Chattillion, E. A., Allison, M., et al. (2012) · SLEEP · doi:10.5665/sleep.1632 · Cited by 64
Vulnerable Caregivers of Alzheimer Disease Patients Have a Deficit in 2-Adrenergic Receptor Sensitivity and Density
Mills, P. J., Adler, K. A., Dimsdale, J. E., Perez, C. J., Ziegler, M. G., Ancoli‐Israel, S., Patterson, T. L., & Grant, I. (2004) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200405000-00007 · Cited by 62
The cultural context of caregiving: a comparison of Alzheimer's caregivers in Shanghai, China and San Diego, California
Patterson, T. L., Semple, S. J., Shaw, W. S., Yu, E., HE, Y., Zhang, M. Y., Wu, W., & Grant, I. (1998) · Psychological Medicine · doi:10.1017/s0033291798007053 · Cited by 62
Self-reported burden among caregivers of patients with multiple sclerosis.
Gupta, S., Goren, A., Phillips, A., & Stewart, M. (2012) · International Journal of MS Care · doi:10.7224/1537-2073-14.4.179 · Cited by 60
Caregivers of Alzheimer's Disease and Stroke Patients: Immunological and Psychological Considerations
Reese, D. R., Gross, A. M., Smalley, D. L., & Messer, S. C. (1994) · The Gerontologist · doi:10.1093/geront/34.4.534 · Cited by 59
Objective and Subjective Cognitive Problems among Caregivers and Matched Non-caregivers
Vitaliano, P. P., Ustundag, O., & Borson, S. (2017) · The Gerontologist · doi:10.1093/geront/gnv690 · Cited by 55
Is Depression in Alzheimer’s Caregivers Really Due to Activity Restriction? A Preliminary Mediational Test of the Activity Restriction Model
Mausbach, B. T., Patterson, T. L., & Grant, I. (2008) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2007.12.001 · Cited by 55
Caregiving Stress Among Community Caregivers for the Elderly: Does Institutionalization Make a Difference?
Dellasega, C. A. (1991) · Journal of Community Health Nursing · doi:10.1207/s15327655jchn0804_2 · Cited by 50
Mental health and wellbeing in spouses of persons with dementia: the Nord-Trøndelag health study
Ask, H., Langballe, E. M., Holmen, J., Selbæk, G., Saltvedt, I. T., & Tambs, K. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-413 · Cited by 49
Effect of Chronic Dementia Caregiving and Major Transitions in the Caregiving Situation on Kidney Function: A Longitudinal Study
von Känel, R., Mausbach, B. T., Dimsdale, J. E., Mills, P. J., Patterson, T. L., Ancoli-Israel, S., Ziegler, M. G., Roepke, S. K., Chattillion, E. A., Allison, M., et al. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3182408c14 · Cited by 49
Burden, Coping and Health Status
Pratt, C. C., Wright, S. D., & Schmall, V. L. (1987) · Journal of Gerontological Social Work · doi:10.1300/j083v10n01_08 · Cited by 47
The meaningfulness of participating in support groups for informal caregivers of older adults with dementia: a systematic review
Lauritzen, J., Pedersen, P. U., Sørensen, E. E., & Bjerrum, M. B. (2015) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/01938924-201513060-00018 · Cited by 46
The Relationship Between Spiritual Perspective, Social Support, and Depression in Caregiving and Noncaregiving Wives
Robinson, K. M., & Kaye, J. (1994) · Research and theory for nursing practice · doi:10.1891/0889-7182.8.4.375 · Cited by 42
Does Caregiving Cause Psychological Distress? The Case for Familial and Genetic Vulnerabilities in Female Twins
VITALIANO, P. P., Strachan, E. D., Dansie, E. J., Goldberg, J. H., & Buchwald, D. (2013) · Annals of Behavioral Medicine · doi:10.1007/s12160-013-9538-y · Cited by 41
Duplicate publication of articles used in meta-analysis in Korea
Choi, W.-S., Song, S.-W., Ock, S.-M., Kim, C.-M., Lee, J.-B., Chang, W.-J., & Kim, S. (2014) · SpringerPlus · doi:10.1186/2193-1801-3-182 · Cited by 37
CD4 and CD8 Counts Are Associated With Interactions of Gender and Psychosocial Stress
Scanlan, J. M., VITALIANO, P. P., Ochs, H. D., Savage, M. V., & Soo Borson, B. (1998) · Psychosomatic Medicine · doi:10.1097/00006842-199809000-00023 · Cited by 37
Relations of caregiving stress and health depend on the health indicators used and gender
Zhang, J., VITALIANO, P. P., & Lin, H.-H. (2006) · International Journal of Behavioral Medicine · doi:10.1207/s15327558ijbm1302_9 · Cited by 36
Predicting Quality of Life in Caregivers of Alzheimer's Patients: The Role of Support from and Involvement with the Religious Community
Burgener, S. C. (1999) · Journal of Pastoral Care · doi:10.1177/002234099905300406 · Cited by 36
Psychosocial Resources as Moderators of the Impact of Spousal Dementia Caregiving on Depression
Adams, K. B., Smyth, K. A., & McClendon, M. J. (2005) · Journal of Applied Gerontology · doi:10.1177/0733464805278812 · Cited by 35
Training programmes for family caregivers of people with dementia living at home: integrative review
Sousa, L., Sequeira, C., Ferré‐Grau, C., Neves, P. P. D., & Fortuño, M. L. (2016) · Journal of Clinical Nursing · doi:10.1111/jocn.13266 · Cited by 35
The meaningfulness of participating in support groups for informal caregivers of older adults with dementia: a systematic review
Lauritzen, J., Pedersen, P. U., Sørensen, E. E., & Bjerrum, M. B. (2015) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2015-2121 · Cited by 34
A Cognitive Psychophysiological Model to Predict Functional Decline in Chronically Stressed Older Adults
VITALIANO, P. P., Echeverria, D., Shelkey, M., Zhang, J., & Scanlan, J. M. (2007) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-007-9071-x · Cited by 33
Cardiometabolic Effects in Caregivers of Nursing Home Placement and Death of Their Spouse with A lzheimer's Disease
von Känel, R., Mausbach, B. T., Dimsdale, J. E., Mills, P. J., Patterson, T. L., Ancoli‐Israel, S., Ziegler, M. G., Roepke, S. K., Chattillion, E. A., Allison, M., et al. (2011) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2011.03634.x · Cited by 32
Lymphocyte Proliferation Is Associated with Gender, Caregiving, and Psychosocial Variables in Older Adults
Scanlan, J. M., VITALIANO, P. P., Zhang, J., Savage, M. V., & Ochs, H. D. (2001) · Journal of Behavioral Medicine · doi:10.1023/a:1012987226388 · Cited by 28
Meta-Analysis and Moderator Analysis: Can the Field Develop Further?
Bloch, M. H. (2014) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2013.12.001 · Cited by 28
An evaluation of a preschool curriculum to educate children in the prevention of sexual abuse
Ratto, R., & Bogat, G. A. (1990) · Journal of Community Psychology · doi:10.1002/1520-6629(199007)18:3 · Cited by 28
Coronary heart disease moderates the relationship of chronic stress with the metabolic syndrome.
VITALIANO, P. P., Scanlan, J. M., Siegler, I. C., McCormick, W. C., & Knopp, R. H. (1998) · Health Psychology · doi:10.1037//0278-6133.17.6.520 · Cited by 27
Perceived caregiver stress in Alzheimer′s disease and mild cognitive impairment: A case control study
Dhikav, V., Anand, K., Sachdeva, A., & Mishra, P. (2015) · Annals of Indian Academy of Neurology · doi:10.4103/0972-2327.167695 · Cited by 24
Consequences of clinical case management for caregivers: a systematic review
Corvol, A., Dreier, A., Prudhomm, J., Thyrian, J. R., Hoffmann, W. U., & Somme, D. (2017) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4679 · Cited by 22
Psychosocial group intervention to enhance self-management skills of people with dementia and their caregivers: study protocol for a randomized controlled trial
Laakkonen, M., Hölttä, E., Savikko, N. M., Strandberg, T. E., Suominen, M. H., & Pitkälä, K. H. (2012) · Trials · doi:10.1186/1745-6215-13-133 · Cited by 20
Carotid Plaque in Alzheimer Caregivers and the Role of Sympathoadrenal Arousal
Roepke, S. K., Chattillion, E. A., von Känel, R., Allison, M., Ziegler, M. G., Dimsdale, J. E., Mills, P. J., Patterson, T. L., Ancoli‐Israel, S., Calleran, S., et al. (2011) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3182081004 · Cited by 19
Does depression prior to caregiving increase vulnerability to depressive symptoms among caregivers of persons with Alzheimer's disease?
Neundorfer, M. M., McClendon, M. J., Smyth, K. A., Strauss, M. E., & McCallum, T. (2006) · Aging & Mental Health · doi:10.1080/13607860600641036 · Cited by 18
Combination of Caregiving Stress and Hormone Replacement Therapy is Associated With Prolonged Platelet Activation to Acute Stress Among Postmenopausal Women
Aschbacher, K., von Känel, R., Mills, P. J., Hong, S., Roepke, S. K., Mausbach, B. T., Patterson, T. L., Ziegler, M. G., Dimsdale, J. E., Ancoli‐Israel, S., et al. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31815a8ba8 · Cited by 13
Family caregiving in dementia in Japan
Yamashita, M., & Amagai, M. (2008) · Applied Nursing Research · doi:10.1016/j.apnr.2007.01.009 · Cited by 13
Optimizing Diagnosis and Management in mild-to-moderate Alzheimer’s Disease
Galvin, J. E. (2012) · Neurodegenerative Disease Management · doi:10.2217/nmt.12.21 · Cited by 9
Supporting Caregivers in Caring: Empowered to Disempowered and Back Again
Petty, M. C. (2015) · Creative Nursing · doi:10.1891/1078-4535.21.2.69 · Cited by 9
Vulnerable Caregivers of Alzheimer Disease Patients Have a Deficit in 2-Adrenergic Receptor Sensitivity and Density
Mills, P. J. (2004) · American Journal of Geriatric Psychiatry · doi:10.1176/appi.ajgp.12.3.281 · Cited by 5
Affective and Behavioral Stress Outcomes in Alzheimer's Caregivers
Burns, E., Fleming, R., Wagstaff, D., Goodwin, J., Hirschman, R., & Greenberg, J. J. (2007) · Journal of Applied Biobehavioral Research · doi:10.1111/j.1751-9861.2002.tb00077.x · Cited by 4
Administration and procedures
Ramshaw, E. (2017) · Routledge eBooks · doi:10.4324/9781315623115-8 · Cited by 3

Research works printed but not linked: 14

Cohen, J. (1988). Statistical power analysis for the behavioural sciences (2nd ed.). New York, NY: Lawrence Erlbaum Associates, Publishers.
Comprehensive Meta-Analysis Software (CMA, Version 3.0). [Computer software]. Englewood, NJ: Biostat Inc. Retrieved from https://www.meta-analysis.com/index.php
10.1111/j.1742-9536.2011.0037.x · DOI
Derogatis, L. R. (1977). SCL-90 Manual I: Scoring, administration and procedures for the SCL-90. Baltimore, MD: Clinical Psychometric Research.
10.1037//0278-6133.13.4.291 · DOI
Higgins, J. P., & Green, S. (Eds.). (2011). http://www.tandf.co.uk/journals/authors/style/reference/tf_APA.pdf Retrieved from www.handbook-cochrane.org
*Olin, J. T., Schneider, L. S., & Kaser-Boyd, N. (1996). Associating personality pathology with emotional distress in caregivers of patients with Alzheimer's disease. Journal of Clinical Geropsychology, 2(2), 93–101.
10.1037/0021-843X.104.1.197 · DOI
Schulz, R., Biegel, D. E., & Blum, A. (Eds.). (1990). Theoretical perspectives on caregiving. Aging and caregiving: Theory, research, and policy. Newbury Park, CA: Sage.
10.1037//0882-7974.6.4.569 · DOI
10.1037//0882-7974.11.1.155 · DOI
*Vitaliano, P. P., Scanlan, J. M., Moe, K., Siegler, I. C., Prinz, P. N., & Ochs, H. D. (2000). Stress, sleep problems, and immune function in persons with cancer histories. Cancer Research Therapy and Control, 10(3), 167–182.
10.1371/journal.pmed.00402 · DOI
10.1093/geront/48.6.732 · DOI

Sorted by citations

2023 Alzheimer's disease facts and figures
(2023) · Alzheimer's & Dementia · doi:10.1002/alz.13016 · Cited by 3,212
2024 Alzheimer's disease facts and figures
(2024) · Alzheimer's & Dementia · doi:10.1002/alz.13809 · Cited by 2,536
2019 Alzheimer’s disease facts and figures.
Alzheimer's Association (2019) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2019.01.010 · Cited by 2,461
2020 Alzheimer's disease facts and figures
(2020) · Alzheimer's & Dementia · doi:10.1002/alz.12068 · Cited by 2,353
2022 Alzheimer's disease facts and figures
Anonymous (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12638 · Cited by 2,469

See all 133

Authors: Ma, M., Dorstyn, D., Ward, L., & Prentice, S.
Affiliations: The University of Adelaide (AU)
Corresponding author: Dorstyn, Diana
ORCID: Dorstyn, Diana
Ward, Lynn
Prentice, Shaun
Venue: Aging & Mental Health
Publisher: Informa UK Limited
Published: 2017-09-05
Volume: 22
Issue: 11
Pages: 1395-1405
ISSN: 1360-7863 (ISSN-L)
1364-6915
DOI: 10.1080/13607863.2017.1370689
OpenAlex: W2751156782
Cited by: 133
References: 123
Citations by year: 2026: 9 · 2025: 19 · 2024: 17 · 2023: 17 · 2022: 21 · 2021: 23 · 2020: 13 · 2019: 7 · 2018: 6 · 2017: 1
FWCI: 6.07
Type: journal article
Language: en
Open access: closed
Locations: Aging & Mental Health (publishedVersion)
PubMed (publishedVersion)
Funders: Dementia Training Australia
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Nursing › Research and Theory › Nursing care and research
Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
Keywords: Alzheimer's disease, caregiver mental health, primary caregivers, depression, anxiety, psychological distress, gender differences, older adults, caregiver burden
MeSH terms: Alzheimer Disease, Anxiety Disorders, Depressive Disorder, Humans, Stress, Psychological, Caregivers, Observational Studies as Topic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Alzheimers’ disease and caregiving: a meta-analytic review comparing the mental health of primary carers to controls

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks