Cited by 133Dementia and Cognitive Impairment ResearchNursing care and researchFamily Caregiving in Mental Illness

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Alzheimers’ disease and caregiving: a meta-analytic review comparing the mental health of primary carers to controls

Ma, Mandy, Dorstyn, Diana, Ward, Lynn, Prentice, Shaun·2018·Aging & Mental Health

DOI 10.1080/13607863.2017.1370689

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Abstract

Objectives To quantitatively review the literature comparing depressed mood, anxiety and psychological distress in caregivers (CGs) of older adults with Alzheimer's disease (AD) with non-caregivers (NCGs) Methods: Eighteen independent studies comparing AD CGs (N = 2378) with NCGs (N = 70,035) were evaluated in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Standardised mean differences (Hedges' g) with associated 95% confidence intervals and p-values were calculated using a random-effects model. Results Studies generally conformed to STROBE criteria in terms of their methodological and procedural detail, although data management issues that may contribute to methodological bias were identified. Pooled effect estimates revealed medium to large group differences in depression (g w = 1.01 [CI: 0.73, 1.29] p w = 0.64 [CI: 0.39, 0.89] p w = 1.58 [CI: 1.11, 2.05], p Discussion Caregivers of patients with AD experience poor mental health in comparison to the general population, with female caregivers being disproportionately affected. Further exploration of the psychosocial variables that contribute to these group differences is needed to inform effective support services and, in turn, help caregivers manage the emotional demands of AD.

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Authors: Ma, M., Dorstyn, D., Ward, L., & Prentice, S.
Affiliations: The University of Adelaide (AU)
Corresponding author: Dorstyn, Diana
ORCID: Dorstyn, Diana
Ward, Lynn
Prentice, Shaun
Venue: Aging & Mental Health
Publisher: Informa UK Limited
Published: 2017-09-05
Volume: 22
Issue: 11
Pages: 1395-1405
ISSN: 1360-7863 (ISSN-L)
1364-6915
DOI: 10.1080/13607863.2017.1370689
OpenAlex: W2751156782
Cited by: 133
References: 123
Citations by year: 2026: 9 · 2025: 19 · 2024: 17 · 2023: 17 · 2022: 21 · 2021: 23 · 2020: 13 · 2019: 7 · 2018: 6 · 2017: 1
FWCI: 6.07
Type: journal article
Language: en
Open access: closed
Locations: Aging & Mental Health (publishedVersion)
PubMed (publishedVersion)
Funders: Dementia Training Australia
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Nursing › Research and Theory › Nursing care and research
Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
Keywords: Alzheimer's disease, caregiver mental health, primary caregivers, depression, anxiety, psychological distress, gender differences, older adults, caregiver burden
MeSH terms: Alzheimer Disease, Anxiety Disorders, Depressive Disorder, Humans, Stress, Psychological, Caregivers, Observational Studies as Topic

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Alzheimers’ disease and caregiving: a meta-analytic review comparing the mental health of primary carers to controls

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