Cited by 170Autism Spectrum Disorder ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesChild and Adolescent Psychosocial and Emotional Development

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Anxiety Disorders Interview Schedule–Autism Addendum: Reliability and Validity in Children With Autism Spectrum Disorder

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Kerns, Connor Morrow, Renno, Patricia, Kendall, Philip C., Wood, Jeffrey J., Storch, Eric A.·2017·Journal of Clinical Child & Adolescent Psychology

DOI 10.1080/15374416.2016.1233501PMC PMC5441235

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Abstract

Assessing anxiety in autism spectrum disorder (ASD) is inherently challenging due to overlapping (e.g., social avoidance) and ambiguous symptoms (e.g., fears of change). An ASD addendum to the Anxiety Disorders Interview Schedule-Child/Parent, Parent Version (ADIS/ASA) was developed to provide a systematic approach for differentiating traditional anxiety disorders from symptoms of ASD and more ambiguous, ASD-related anxiety symptoms. Interrater reliability and convergent and discriminant validity were examined in a sample of 69 youth with ASD (8-13 years, 75% male, IQ = 68-143) seeking treatment for anxiety. The parents of participants completed the ADIS/ASA and a battery of behavioral measures. A second rater independently observed and scored recordings of the original interviews. Findings suggest reliable measurement of comorbid (intraclass correlation = 0.85-0.98, κ = 0.67-0.91) as well as ambiguous anxiety-like symptoms (intraclass correlation = 0.87-95, κ = 0.77-0.90) in children with ASD. Convergent and discriminant validity were supported for the traditional anxiety symptoms on the ADIS/ASA, whereas convergent and discriminant validity were partially supported for the ambiguous anxiety-like symptoms. Results provide evidence for the reliability and validity of the ADIS/ASA as a measure of traditional anxiety categories in youth with ASD, with partial support for the validity of the ambiguous anxiety-like categories. Unlike other measures, the ADIS/ASA differentiates comorbid anxiety disorders from overlapping and ambiguous anxiety-like symptoms in ASD, allowing for more precise measurement and clinical conceptualization. Ambiguous anxiety-like symptoms appear phenomenologically distinct from comorbid anxiety disorders and may reflect either symptoms of ASD or a novel variant of anxiety in ASD.

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Authors: Kerns, C. M., Renno, P., Kendall, P. C., Wood, J. J., & Storch, E. A.
Affiliations: Drexel University (US)
University of California, Los Angeles (US)
Temple University (US)
University of South Florida (US)
Corresponding author: Kerns, Connor Morrow
ORCID: Kerns, Connor Morrow
Renno, Patricia
Kendall, Philip C.
Wood, Jeffrey J.
Storch, Eric A.
Venue: Journal of Clinical Child & Adolescent Psychology
Publisher: Informa UK Limited
Published: 2016-12-07
Volume: 46
Issue: 1
Pages: 88-100
ISSN: 1537-4416 (ISSN-L)
1537-4424
DOI: 10.1080/15374416.2016.1233501
PMC: PMC5441235
OpenAlex: W2560791324
Cited by: 170
References: 45
Citations by year: 2026: 9 · 2025: 22 · 2024: 22 · 2023: 14 · 2022: 21 · 2021: 21 · 2020: 20 · 2019: 18 · 2018: 12 · 2017: 11
FWCI: 8.70
Type: journal article
Language: en
Update notices: correction (2019-05-24)
Open access: green
www.ncbi.nlm.nih.gov
Locations: Journal of Clinical Child & Adolescent Psychology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Digital Commons - University of South Florida (University of South Florida) (submittedVersion)
Funders: Autism Science Foundation
National Institute of Child Health and Human Development (R01 HD080097)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords: autism spectrum disorder, anxiety disorders, anxiety comorbidity, social avoidance, inter-rater reliability, convergent validity, discriminant validity, children and adolescents
MeSH terms: Autism Spectrum Disorder, Adolescent, Anxiety, Anxiety Disorders, Child, Female, Humans, Male, Parents, Psychometrics, Severity of Illness Index, Reproducibility of Results

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Anxiety Disorders Interview Schedule–Autism Addendum: Reliability and Validity in Children With Autism Spectrum Disorder

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