Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

Gene expression regulation mediated through reversible m6A RNA methylation

Fu, Y., Dominissini, D., Rechavi, G., & He, C. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3724 · Cited by 1,961

The Structure of the Eukaryotic Ribosome at 3.0 Å Resolution

Shem, A. B., de Loubresse, N. G., Melnikov, S. V., Jenner, L. B., Yusupova, G. Z., & Yusupov, M. (2011) · Science · doi:10.1126/science.1212642 · Cited by 1,187

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

Carlile, T. M., Rojas-Durán, M. F., Zinshteyn, B., Shin, H., Bartoli, K. M., & Gilbert, W. V. (2014) · Nature · doi:10.1038/nature13802 · Cited by 1,042

Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

Schwartz, S., Bernstein, D. A., Mumbach, M. R., Jovanović, M., Herbst, R. H., León-Ricardo, B. X., Engreitz, J., Guttman, M., Satija, R., Lander, E. S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.08.028 · Cited by 1,013

MODOMICS: a database of RNA modification pathways—2013 update

Machnicka, M. A., Milanowska, K., Oglou, O. O., Purta, E., Kurkowska, M., Olchowik, A., Januszewski, W., Kalinowski, S., Dunin-Horkawicz, S., Rother, K. M., et al. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1007 · Cited by 1,003

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions

Heiss, N. S., Knight, S. W., Vulliamy, T. J., Klauck, S. M., Wiemann, S., Mason, P. J., Poustka, A., & Dokal, I. (1998) · Nature Genetics · doi:10.1038/ng0598-32 · Cited by 976

Site-Specific Ribose Methylation of Preribosomal RNA: A Novel Function for Small Nucleolar RNAs

Kiss-László, Z., Henry, Y. A. L., Bachellerie, J., Caizergues‐Ferrer, M., & Kiss, T. (1996) · Cell · doi:10.1016/s0092-8674(00)81308-2 · Cited by 855

The RNA modification database, RNAMDB: 2011 update

Cantara, W. A., Crain, P. F., Rozenski, J., McCloskey, J. A., Harris, K. A., Zhang, X., Vendeix, F. A. P., Fabris, D., & Agris, P. F. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1028 · Cited by 822

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

Woolford, J. L., & Baserga, S. J. (2013) · Genetics · doi:10.1534/genetics.113.153197 · Cited by 780

Specialized ribosomes: a new frontier in gene regulation and organismal biology

Xue, S., & Barna, M. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3359 · Cited by 730

Modification of Adenosine196 by Mettl3 Methyltransferase in the 5’-External Transcribed Spacer of 47S Pre-rRNA Affects rRNA Maturation

Sergeeva, O. V., Sergeev, P., Melnikov, P., Prikazchikova, T. A., Dontsova, O. А., & Zatsepin, T. S. (2020) · Cells · doi:10.3390/cells9041061 · Cited by 17

A conserved Bcd1 interaction essential for box C/D snoRNP biogenesis

Khoshnevis, S., Dreggors-Walker, R. E., Hoffmann, T. F. R., & Ghalei, H. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.010222 · Cited by 17

The chemical landscape of the human ribosome at 1.67 Å resolutionPreprint

Faille, A., Dent, K. C., Pellegrino, S., Jaako, P., & Warren, A. J. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.28.530191 · Cited by 17

Global Co-regulatory Cross Talk Between m6A and m5C RNA Methylation Systems Coordinate Cellular Responses and Brain Disease Pathways

Orji, O. C., Stones, J., Rajani, S., Markus, R., Öz, M. D., & Knight, H. M. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04555-0 · Cited by 17

RNA epigenetic modifications as dynamic biomarkers in cancer: from mechanisms to clinical translation

Zhao, Y., Chen, X., Zhang, X., & Liu, H. (2025) · Biomarker Research · doi:10.1186/s40364-025-00794-y · Cited by 18

Box C/D small nucleolar ribonucleoproteins regulate mitochondrial surveillance and innate immunity

Tjahjono, E., Revtovich, A. V., & Kirienko, N. V. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010103 · Cited by 16

The Arabidopsis Mitochondrial Pseudouridine Synthase Homolog FCS1 Plays Critical Roles in Plant Development

Niu, Y., Yuan, Z., Zhu, H., Zhao, H., Nie, K., Wang, X., Sun, L., & Song, C. (2022) · Plant and Cell Physiology · doi:10.1093/pcp/pcac060 · Cited by 16

Site‐Specific Labeling of RNAs with Modified and 19F‐Labeled Nucleotides by Chemo‐Enzymatic Synthesis

Sudakov, A., Knezic, B., Hengesbach, M., Fürtig, B., Stirnal, E., & Schwalbe, H. (2023) · Chemistry - A European Journal · doi:10.1002/chem.202203368 · Cited by 16

Ribosomal Biogenesis and Heterogeneity in Development, Disease, and Aging

Islam, R. A., & Rallis, C. (2023) · Epigenomes · doi:10.3390/epigenomes7030017 · Cited by 16

The regulatory roles of small nucleolar RNAs within their host locus

Fafard-Couture, É., Labialle, S., & Scott, M. S. (2024) · RNA Biology · doi:10.1080/15476286.2024.2342685 · Cited by 18

Exploring pseudouridylation: dysregulation in disease and therapeutic potential

Guillen-Angel, M., & Roignant, J. (2024) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2024.102210 · Cited by 15

Cryo‐EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 Å resolution

Golubev, A. A., Fatkhullin, B. F., Khusainov, I. S., Jenner, L. B., Gabdulkhakov, A. G., Validov, S. Z., Yusupova, G. Z., Yusupov, M., & Сергеевич, У. К. (2020) · FEBS Letters · doi:10.1002/1873-3468.13915 · Cited by 16

Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion

Verma, G., Bowen, A., Gheibi, S., Hamilton, A., Muthukumar, S., Cataldo, L. R., Asplund, O., Esguerra, J. L. S., Karagiannopoulos, A., Lyons, C., et al. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.101692 · Cited by 17

Structural modules of the stress-induced protein HflX: an outlook on its evolution and biological role

Srinivasan, K., Dey, S., & Sengupta, J. (2018) · Current Genetics · doi:10.1007/s00294-018-0905-x · Cited by 16

A dual role of the ribosome-bound chaperones RAC/Ssb in maintaining the fidelity of translation termination

Gribling-Burrer, A.-S., Chiabudini, M., Zhang, Y., Qiu, Z., Scazzari, M., Wölfle, T., Wohlwend, D., & Rospert, S. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz334 · Cited by 16

Guide RNA acrobatics: positioning consecutive uridines for pseudouridylation by H/ACA pseudouridylation loops with dual guide capacityPreprint

Jády, B. E., Ketele, A., Moulis, D., & Kiss, T. (2021) · Genes & Development · doi:10.1101/gad.349072.121 · Cited by 16

Advanced reactivity-based sequencing methods for mRNA epitranscriptome profiling

Cai, Z., Song, P., Yu, K., & Jia, G. (2024) · RSC Chemical Biology · doi:10.1039/d4cb00215f · Cited by 14

SNORD113–114 cluster maintains haematopoietic stem cell self-renewal via orchestrating the translation machinery

Wang, H., Zhang, Z., Han, C., Jiang, P., Xu, J., Han, Y., Huang, D., Li, J., Zhou, J. R., Durnin, M., et al. (2025) · Nature Cell Biology · doi:10.1038/s41556-024-01593-7 · Cited by 19

A N7-Methylguanine-Related Gene Signature Applicable for the Prognosis and Microenvironment of Prostate Cancer

Mei, W., Jia, X., Xin, S., Liu, X., Jin, L., Sun, X., Zhang, J., Zhang, B., Yang, G., Chen, P., et al. (2022) · Journal of Oncology · doi:10.1155/2022/8604216 · Cited by 15

The RNA-Binding Function of Ribosomal Proteins and Ribosome Biogenesis Factors in Human Health and Disease

Catalanotto, C., Barbato, C., Cogoni, C., & Benelli, D. (2023) · Biomedicines · doi:10.3390/biomedicines11112969 · Cited by 17

AlkB-Facilitated Demethylation Enables Quantitative and Site-Specific Detection of Dual Methylation of Adenosine in RNA

Guo, X., Xie, N., Chen, W., Ji, T., Xiong, J., Feng, T., Wang, M., Zhang, S., Gu, S.-Y., Feng, Y., et al. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c04457 · Cited by 15

Mass Spectrometry-Based Pipeline for Identifying RNA Modifications Involved in a Functional Process: Application to Cancer Cell Adaptation

Amalric, A., Attina, A., Bastide, A., Buffard, M., Mateus, S., Planque, C., Rivals, É., Hirtz, C., & David, A. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.3c02635 · Cited by 15

The kinase Rio1 and a ribosome collision-dependent decay pathway survey the integrity of 18S rRNA cleavage

Parker, M. D., Brunk, E. S., Getzler, A. J., & Karbstein, K. (2024) · PLoS Biology · doi:10.1371/journal.pbio.3001767 · Cited by 15

Crossing boundaries of light microscopy resolution discerns novel assemblies in the nucleolus

Correll, C. C., Rudloff, U., Schmit, J. D., Ball, D. A., Karpova, T., Balzer, E. M., & Dundr, M. (2024) · Histochemistry and Cell Biology · doi:10.1007/s00418-024-02297-7 · Cited by 14

Implication of ribosomal protein in abiotic and biotic stress

Fakih, Z., & Germain, H. (2025) · Planta · doi:10.1007/s00425-025-04665-6 · Cited by 15

The 23S Ribosomal RNA From Pyrococcus furiosus Is Circularly Permuted

Birkedal, U., Beckert, B., Wilson, D. N., & Nielsen, H. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.582022 · Cited by 14

The Importance of the Epi-Transcriptome in Translation Fidelity

Valadon, C., & Namy, O. (2021) · Non-Coding RNA · doi:10.3390/ncrna7030051 · Cited by 19

Interplay of RNA 2′-O-methylations with viral replication

Decombe, A., Kazzi, P. E., & Decroly, É. (2023) · Current Opinion in Virology · doi:10.1016/j.coviro.2023.101302 · Cited by 15

METTL5, an 18S rRNA-specific m 6 A methyltransferase, modulates expression of stress response genesPreprint

Chen, H., Liu, Q., Yu, D., Natchiar, K., Zhou, C., Hsu, C.-H., Hsu, P., Zhang, X., Klaholz, B. P., Gregory, R. I., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.27.064162 · Cited by 15

Decoding the epitranscriptome: a new frontier for cancer therapy and drug resistance

Tang, L., Tian, H., Min, Q., You, H., Yin, M., Yang, L., Zhao, Y., Wu, X., Li, M., Du, F., et al. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01854-w · Cited by 14

Diversification of piRNAs expressed in PGCs and somatic cells during embryonic gonadal development

Barreñada, O., Fernández-Pérez, D., Larriba, E., Brieño‐Enríquez, M. A., & del Mazo, J. (2020) · RNA Biology · doi:10.1080/15476286.2020.1757908 · Cited by 15

The dysregulation of lncRNAs by epigenetic factors in human pathologies

Zhang, Y., Wang, X., Zhang, C., & Yi, H. (2023) · Drug Discovery Today · doi:10.1016/j.drudis.2023.103664 · Cited by 14

How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA

Höbartner, C., Bohnsack, K. E., & Bohnsack, M. T. (2024) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-030222-112310 · Cited by 16

Complete list of canonical post-transcriptional modifications in the Bacillus subtilis ribosome and their link to RbgA driven large subunit assembly

Popova, A. M., Jain, N., Dong, X., Abdollah-Nia, F., Britton, R. A., & Williamson, J. R. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae626 · Cited by 14

The dual life of disordered lysine-rich domains of snoRNPs in rRNA modification and nucleolar compaction

Dominique, C., Maiga, N. K., Méndez-Godoy, A., Pillet, B., Hamze, H., Léger‐Silvestre, I., Henry, Y. A. L., Marchand, V., Neto, V. G., Dez, C., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-53805-1 · Cited by 14

At least two molecules of the RNA helicase Has1 are simultaneously present in pre-ribosomes during ribosome biogenesis

Gnanasundram, S. V., Kos‐Braun, I. C., & Koš, M. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz767 · Cited by 17

Genes for RNA-binding proteins involved in neural-specific functions and diseases are downregulated in Rubinstein-Taybi iNeurons

Larizza, L., Calzari, L., Alari, V., & Russo, S. (2021) · Neural Regeneration Research · doi:10.4103/1673-5374.314286 · Cited by 13

RNA methyltransferases in plants: Breakthroughs in function and evolution

Ferraz, R., Coimbra, S., Correia, S. I., & Canhoto, J. (2022) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2022.12.001 · Cited by 15

Sirtuin 7 promotes 45S pre-rRNA cleavage at site 2 and determines the processing pathway

Sirri, V., Grob, A., Berthelet, J., Jourdan, N., & Roussel, P. (2019) · Journal of Cell Science · doi:10.1242/jcs.228601 · Cited by 14

Sgd1 is an MIF4G domain-containing cofactor of the RNA helicase Fal1 and associates with the 5’ domain of the 18S rRNA sequence

Gallesio, J. D., Hackert, P., Bohnsack, K. E., & Bohnsack, M. T. (2020) · RNA Biology · doi:10.1080/15476286.2020.1716540 · Cited by 14

The importance of RNA modifications: From cells to muscle physiology

Das, A. S., Alfonzo, J. D., & Accornero, F. (2021) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1700 · Cited by 14

Enzymatic Reactions of S-Adenosyl-L-Methionine: Synthesis and Applications

Rudenko, A. Y., Mariasina, S. S., Ozhiganov, R. M., Владимирович, С. П., & Polshakov, V. I. (2025) · Biochemistry (Moscow) · doi:10.1134/s0006297924604210 · Cited by 13

Insight Into the Roles of Non-coding RNA in Bronchopulmonary Dysplasia

Xi, Y., & Wang, Y. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.761724 · Cited by 13

Research Progress of RNA Methylation Modification in Colorectal Cancer

Liang, W., Yi, H., Mao, C., Meng, Q., Wu, X., Li, S., & Xue, J. W. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.903699 · Cited by 13

Towards the structural characterization of the human methyltransferome

Fenwick, M. K., & Ealick, S. E. (2018) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2018.03.007 · Cited by 13

From Snapshots to Flipbook—Resolving the Dynamics of Ribosome Biogenesis with Chemical Probes

Kofler, L., Prattes, M., & Bergler, H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082998 · Cited by 13

Design of function-regulating RNA via deep learning and AlphaFold 3

Xia, Y., Liang, Z., Du, X., Cao, D., Li, J., Sun, L., Huo, Y., & Guo, S. (2025) · Briefings in Bioinformatics · doi:10.1093/bib/bbaf419 · Cited by 13

Ribosome Specialization in Protozoa Parasites

Rodríguez-Almonacid, C. C., Kellogg, M. K., Karamyshev, A. L., & Karamysheva, Z. N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087484 · Cited by 12

Ribonucleic Acid-Mediated Control of Protein Translation Under Stress

Payea, M. J., Dar, S. A., Malla, S., & Maragkakis, M. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0233 · Cited by 11

Design patterns of biological cells

Andrews, S. S., Wiley, H. S., & Sauro, H. M. (2024) · BioEssays · doi:10.1002/bies.202300188 · Cited by 15

Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1

Zakrzewska‐Placzek, M., Golisz, A., Kwaśnik, A., Krzysztoń, M., Niedźwiecka, K., & Kufel, J. (2025) · Plant Cell & Environment · doi:10.1111/pce.15425 · Cited by 13

Identification of Abundant and Functional dodecaRNAs (doRNAs) Derived from Ribosomal RNA

Lambert, M., Benmoussa, A., Diallo, I., Ouellet-Boutin, K., Dorval, V., Majeau, N., Joly-Beauparlant, C., Droit, A., Bergeron, A., Têtu, B., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189757 · Cited by 12

Studies of mutations of assembly factor Hit1 in budding yeast suggest translation defects as the molecular basis for PEHO syndrome

Dreggors-Walker, R. E., Cohen, L. N., Khoshnevis, S., Marchand, V., Motorin, Y., & Ghalei, H. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102261 · Cited by 12

Ribosome changes reprogram translation for chemosurvival in G0 leukemic cells

Datta, C., Truesdell, S. S., Wu, K. Q., Bukhari, S. I. A., Ngue, H., Buchanan, B., Tonquèze, O. L., Lee, S., Kollu, S., Granovetter, M. A., et al. (2022) · Science Advances · doi:10.1126/sciadv.abo1304 · Cited by 15

Overexpression of 18S rRNA methyltransferase CrBUD23 enhances biomass and lutein content in Chlamydomonas reinhardtii

Liu, C., Guo, H., Zhao, X., Zou, B., Sun, T., Feng, J., Zeng, Z., Wen, X., Chen, J., Hu, Z., et al. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1102098 · Cited by 12

Protein folding and tRNA biology

Marı́n, M., Fernández-Calero, T., & Ehrlich, R. (2017) · Biophysical Reviews · doi:10.1007/s12551-017-0322-2 · Cited by 13

Analyzing Ribosome Remodeling in Health and Disease

Petelski, A. A., & Slavov, N. (2020) · PROTEOMICS · doi:10.1002/pmic.202000039 · Cited by 13

rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly

Sekulski, K., Cruz, V. E., Weirich, C. S., & Erzberger, J. P. (2023) · Nature Communications · doi:10.1038/s41467-023-36867-5 · Cited by 12

Integrated Metabolomic and Transcriptomic Analysis of Modified Nucleosides for Biomarker Discovery in Clear Cell Renal Cell Carcinoma

Mohl, D. A., Lagies, S., Zodel, K., Zumkeller, M., Peighambari, A., Ganner, A., Plattner, D. A., Neumann‐Haefelin, E., Adlesic, M., Frew, I. J., et al. (2023) · Cells · doi:10.3390/cells12081102 · Cited by 12

Enhanced Ribonucleic Acid Production by High-Throughput Screening Based on Fluorescence Activation and Transcriptomic-Guided Fermentation Optimization in Saccharomyces cerevisiae

Wu, Y., Lei, S., Lu, C., Li, J., Du, G., & Liu, Y. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c01677 · Cited by 11

Live Cell Imaging and Real-Time Monitoring of Nucleolus Morphology and Mitophagy with a Red Fluorescent and Photostable rRNA-Specific Probe in Human Cancer Cells

Luo, J., Long, W. S., Chen, Z., Wang, S., Zeng, Y., Lu, Y., Zheng, B., She, M., & Wong, W. (2024) · ACS Sensors · doi:10.1021/acssensors.3c02764 · Cited by 11

The rRNA epitranscriptome and myonuclear SNORD landscape in skeletal muscle fibers contributes to ribosome heterogeneity and is altered by a hypertrophic stimulus

Cui, M., Jannig, P. R., Halladjian, M., Figueiredo, V. C., Wen, Y., Vechetti, I. J., Krogh, N., Jude, B., Edman, S., Lanner, J. T., et al. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00301.2024 · Cited by 13

Keep calm and reboot – how cells restart transcription after DNA damage and DNA repair

Donnio, L., & Giglia‐Mari, G. (2024) · FEBS Letters · doi:10.1002/1873-3468.14964 · Cited by 11

Impacts of ribosomal RNA sequence variation on gene expression and phenotype

Welfer, G. A., Brady, R. A., Natchiar, S. K., Watson, Z. L., Rundlet, E. J., Alejo, J. L., Singh, A. P., Mishra, N. K., Altman, R. B., & Blanchard, S. C. (2025) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2023.0379 · Cited by 11

Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism

Ogawa, A., Watanabe, S. P., Ozerova, I., Tsai, A. Y., Kuchitsu, Y., Chong, H. B., Kawakami, T., Fuse, J., Han, W., Kudo, R., et al. (2025) · Cell · doi:10.1016/j.cell.2025.07.041 · Cited by 11

Impact of Ribosome Activity on SARS-CoV-2 LNP – Based mRNA Vaccines

Tsiambas, E., Chrysovergis, A., PAPANIKOLAOU, V. S., MASTRONIKOLIS, N. S., Ragos, V., Batistatou, A. K., Peschos, D., Kavantzas, N., Lazaris, A. C., & Kyrodimos, E. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.654866 · Cited by 11

Exploring Evidence of Non-coding RNA Translation With Trips-Viz and GWIPS-Viz Browsers

Zaheed, O., Kiniry, S. J., Baranov, P. V., & Dean, K. A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.703374 · Cited by 13

Post-transcriptional diversity in riboproteins and RNAs in aging and cancer

da Cruz, J. B., & Lemos, B. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2021.08.012 · Cited by 10

H/ACA snRNP–dependent ribosome biogenesis regulates translation of polyglutamine proteins

Breznak, S. M., Peng, Y., Deng, L., Kotb, N. M., Flamholz, Z., Rapisarda, I. T., Martin, E. T., LaBarge, K. A., Fabris, D., Gavis, E. R., et al. (2023) · Science Advances · doi:10.1126/sciadv.ade5492 · Cited by 11

Nucleolar stress in Drosophila neuroblasts, a model for human ribosomopathies

Baral, S. S., Lieux, M. E., & DiMario, P. J. (2020) · Biology Open · doi:10.1242/bio.046565 · Cited by 15

Arginine Methylation Regulates Ribosome CAR Function

Scopino, K., Dalgarno, C., Nachmanoff, C., Krizanc, D., Thayer, K. M., & Weir, M. P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031335 · Cited by 11

Drug Development for Target Ribosomal Protein rpL35/uL29 for Repair of LAMB3R635X in Rare Skin Disease Epidermolysis Bullosa

Rathner, A., Rathner, P., Friedrich, A., Wießner, M., Kitzler, C. M., Schernthaner, J., Karl, T. R., Krauss, J. B., Lottspeich, F., Mewes, W., et al. (2021) · Skin Pharmacology and Physiology · doi:10.1159/000513260 · Cited by 13

Human DIMT1 generates N26,6A-dimethylation–containing small RNAs

Shen, H., Gonskikh, Y., Stoute, J., & Liu, K. F. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.101146 · Cited by 11

Identification of Small Nucleolar RNA SNORD60 as a Potential Biomarker and Its Clinical Significance in Lung Adenocarcinoma

Zhou, H., Yao, Y., Li, Y., Guo, N., Zhang, H., Wang, Z., Chen, Y., & Dai, G. (2022) · BioMed Research International · doi:10.1155/2022/5501171 · Cited by 12

Adult biphasic pulmonary blastoma.

Jethava, A., & Dasanu, C. A. (2013) · PubMed · Cited by 11

The Ptch/SPOUT1 methyltransferase deposits an m 3 U modification on 28 S rRNA for normal ribosomal function in flies and humans

Chen, J., Bai, Y., Huang, Y., Cui, M., Wang, Y., Gu, Z., Wu, X., Li, Y., & Rong, Y. S. (2024) · Science Advances · doi:10.1126/sciadv.adr1743 · Cited by 11

Rbp95 binds to 25S rRNA helix H95 and cooperates with the Npa1 complex during early pre-60S particle maturation

Bhutada, P., Favre, S., Jaafar, M., Hafner, J., Liesinger, L., Unterweger, S., Bischof, K., Darnhofer, B., Sankar, D. S., Rechberger, G. N., et al. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac724 · Cited by 10

The daunting task of modifying ribosomal RNA

Meier, U. T. (2022) · RNA · doi:10.1261/rna.079391.122 · Cited by 10

Analysis of Expression Pattern of snoRNAs in Human Cells A549 Infected by Influenza A Virus

Zhuravlev, E. S., Sergeeva, M. V., Malanin, S., Амирханов, Р. Н., Semenov, D. V., Grigoryeva, T. V., Komissarov, A. B., & Stepanov, G. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232213666 · Cited by 10

The DEAD-box protein Dbp6 is an ATPase and RNA annealase interacting with the peptidyl transferase center (PTC) of the ribosome

Khreiss, A., Capeyrou, R., Lebaron, S., Albert, B., Bohnsack, K. E., Bohnsack, M. T., Henry, Y. A. L., Henras, A. K., & Humbert, O. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkac1196 · Cited by 10

Disruption of the mouse liver epitranscriptome by long-term aroclor 1260 exposure

Piell, K. M., Petri, B. J., Head, K. Z., Wahlang, B., Xu, R., Zhang, X., Pan, J., Rai, S. N., de Silva, K., Chariker, J. H., et al. (2023) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2023.104138 · Cited by 10

Internal RNA 2′-O-methylation on the HIV-1 genome impairs reverse transcription

Decombe, A., Peersen, O. B., Sutto‐Ortiz, P., Chamontin, C., Piorkowski, G., Canard, B., Nisole, S., & Decroly, É. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad1134 · Cited by 10

Processing of coding and non-coding RNAs in plant development and environmental responses

Si, F., Cao, X., Song, X., & Deng, X. M. (2020) · Essays in Biochemistry · doi:10.1042/ebc20200029 · Cited by 10

Transcriptome-Wide Detection of Internal N7-Methylguanosine

Zhang, L., Liu, C., & He, C. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1374-0_6 · Cited by 10

Saccharomyces cerevisiae, a Powerful Model for Studying rRNA Modifications and Their Effects on Translation Fidelity

Baudin‐Baillieu, A., & Namy, O. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147419 · Cited by 10

Dynamics and thermal sensitivity of rRNA maturation paths in plants

Shanmugam, T., Streit, D., Schroll, F., Kovacevic, J., & Schleiff, E. (2021) · Journal of Experimental Botany · doi:10.1093/jxb/erab434 · Cited by 10

Lytic Reactivation of the Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Is Accompanied by Major Nucleolar Alterations

Atari, N., Rajan, K. S., Chikne, V., Cohen‐Chalamish, S., Doniger, T., Orbaum-Harel, O., Jacob, A., Kalt, I., Michaeli, S., & Sarid, R. (2022) · Viruses · doi:10.3390/v14081720 · Cited by 9

Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome

García-Campos, M. A., Georgeson, J., Nir, R., Reichelt, R., Fluke, K. A., Matzov, D., Iyer, V., Burkhart, B. W., Lui, L. M., Kustanovich, A., et al. (2025) · Cell · doi:10.1016/j.cell.2025.09.014 · Cited by 9

BRPCA: Bounded Robust Principal Component Analysis to Incorporate Similarity Network for N7-Methylguanosine(m7G) Site-Disease Association Prediction

Ma, J., Zhang, L., Li, S., & Liu, H. (2021) · IEEE Transactions on Computational Biology and Bioinformatics · doi:10.1109/tcbb.2021.3109055 · Cited by 9

Construction of a Novel Prognostic Model in Lung Adenocarcinoma Based on 7-Methylguanosine-Related Gene Signatures

Lu, F., Gao, J., Hou, Y., Cao, K., Xia, Y., Chen, Z., Yu, H., Chang, L., & Li, W. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.876360 · Cited by 9

Ribosomopathies and cancer: pharmacological implications

Temaj, G., Saha, S., Dragusha, S., Ejupi, V., Buttari, B., Profumo, E., Beqa, L., & Saso, L. (2022) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2022.2098110 · Cited by 9

Autophagy‐dependent alternative splicing of ribosomal protein S24 produces a more stable isoform that aids in hypoxic cell survival

Kerry, J., Specker, E. J., Mizzoni, M., Brumwell, A., Fell, L., Goodbrand, J., Rosen, M. N., & Uniacke, J. (2024) · FEBS Letters · doi:10.1002/1873-3468.14804 · Cited by 8

Dysregulation of Small Nucleolar RNAs in B-Cell Malignancies

Verbeek, M. W. C., Erkeland, S. J., & van der Velden, V. H. J. (2022) · Biomedicines · doi:10.3390/biomedicines10061229 · Cited by 9

N7-methylguanosine-related lncRNAs: Predicting the prognosis and diagnosis of colorectal cancer in the cold and hot tumors

Wu, J., Song, Q., Huang, C., Shao, Y., Wang, Z.-L., Zhang, H., & Fu, Z. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.952836 · Cited by 9

Ribosomal flavours: An acquired taste for specific mRNAs?

Bates, C., Hubbard, S. J., & Ashe, M. P. (2018) · Biochemical Society Transactions · doi:10.1042/bst20180160 · Cited by 8

Harnessing weedy rice as functional food and source of novel traits for crop improvement

Bhupenchandra, I., Chongtham, S. K., Devi, A. G., Dutta, P., Lamalakshmi, E., Mohanty, S., Choudhary, A. K., Das, A., Sarika, K., Kumar, S., et al. (2024) · Plant Cell & Environment · doi:10.1111/pce.14868 · Cited by 8

m7G RNA methylation in cancer: Effect, mechanism and clinical application

Dang, P., Li, K., & Sun, Z. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70521 · Cited by 8

Orchestrating ribosomal RNA folding during ribosome assembly

Oborská‐Oplová, M., Gerhardy, S., & Panse, V. G. (2022) · BioEssays · doi:10.1002/bies.202200066 · Cited by 8

The Importance of Being RNA-est: considering RNA-mediated ribosome plasticity

Trahan, C., & Oeffinger, M. (2023) · RNA Biology · doi:10.1080/15476286.2023.2204581 · Cited by 8

CRISPR/Cas9-mediated knockout of the ubiquitin variant UbKEKS reveals a role in regulating nucleolar structures and composition

Frion, J., Meller, A., Marbach, G., Lévesque, D., Roucou, X., & Boisvert, F. (2023) · Biology Open · doi:10.1242/bio.059984 · Cited by 8

Synthesis, Function, and Heterogeneity of snoRNA-Guided Posttranscriptional Nucleoside Modifications in Eukaryotic Ribosomal RNAs

Henras, A. K., Plisson‐Chastang, C., Humbert, O., Roméo, Y., & Henry, Y. A. L. (2017) · The Enzymes · doi:10.1016/bs.enz.2017.03.007 · Cited by 41

Concerted modification of nucleotides at functional centers of the ribosome revealed by single-molecule RNA modification profiling

Bailey, A. D., Talkish, J., Ding, H., Igel, H., Durán, A., Mantripragada, S., Paten, B., & Ares, M. (2022) · eLife · doi:10.7554/elife.76562 · Cited by 44

Conserved ribosomal RNA modification and their putative roles in ribosome biogenesis and translation

Lapeyre, B. (2004) · Topics in current genetics · doi:10.1007/b105433 · Cited by 21

Ribosomal RNA modifications within the A-site of the large subunit : consequences for ribosome assembly and translation

Yelland, J. N. (2023) · Texas Digital Library (University of Texas) · doi:10.26153/tsw/59300

The ribosome epitranscriptome: inert—or a platform for functional plasticity?

Georgeson, J. M., & Schwartz, S. (2021) · RNA · doi:10.1261/rna.078859.121 · Cited by 21