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Moderate alcohol use and reduced mortality risk: Systematic error in prospective studies
Abstract
The majority of prospective studies on alcohol use and mortality risk indicates that abstainers are at increased risk of mortality from both all causes and coronary heart disease (CHD). This meta-analysis of 54 published studies tested the extent to which a systematic misclassification error was committed by including as ‘abstainers’ many people who had reduced or stopped drinking, a phenomenon associated with ageing and ill health. The studies judged to be error free found no significant all-cause or cardiac protection, suggesting that the cardiac protection afforded by alcohol may have been over-estimated. Estimates of mortality from heavier drinking may also be higher than previously estimated.
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Self-citation
Metadata
- Authors
- Fillmore, K. M., Kerr, W. C., Stockwell, T., Chikritzhs, T., & Bostrom, A.
- Affiliations
- University of California, San Francisco (US)
- Alcohol Research Group (US)
- University of Victoria (CA)
- Curtin University (AU)
- Corresponding author
- Fillmore, Kaye Middleton
- Venue
- Addiction Research & Theory
- Publisher
- Informa UK Limited
- Published
- 2006-01
- Volume
- 14
- Issue
- 2
- Pages
- 101-132
- ISSN
- 1058-6989 (ISSN-L)
- 1606-6359
- 1476-7392
- OpenAlex
- W2058841902
- Cited by
- 295
- References
- 114
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 5 · 2023: 2 · 2022: 9 · 2021: 9 · 2020: 10 · 2019: 6 · 2018: 13 · 2017: 11 · 2016: 22 · 2015: 13 · 2014: 14 · 2013: 23 · 2012: 20
- FWCI
- 21.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Addiction Research & Theory (publishedVersion)
- eSpace (Curtin University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
- Keywords
- alcohol consumption, mortality risk, coronary artery disease, all-cause mortality, misclassification, heavy drinking, aging, prospective study, cardioprotection
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