Cited by 203Gut microbiota and healthInfant Nutrition and HealthOral microbiology and periodontitis research

The DOI matches its Crossref record; 49 of the 51 references it cites were found in a registry or an index.

Pregnancy-related changes in the maternal gut microbiota are dependent upon the mother's periconceptional diet

Open access

Gohir, Wajiha, Whelan, Fiona J, Surette, Michael G, Moore, Caroline, Schertzer, Jonathan D, Sloboda, Deborah M·2015·Gut Microbes

DOI 10.1080/19490976.2015.1086056PMC PMC4826136

Open this paper in CoChat — free account Open PDF

Abstract

Shifts in the maternal gut microbiome have been implicated in metabolic adaptations to pregnancy. We investigated how pregnancy and diet interact to influence the composition of the maternal gut microbiota. Female C57BL/6 mice were fed either a control or a high fat diet for 8 weeks prior to mating. After confirmation of pregnancy, maternal weight gain and food intake were recorded. Fecal pellets were collected at 2 timepoints prior to mating (at the beginning of the experiment, and after 6 weeks of the specified diet) and at 4 timepoints during pregnancy (gestation day 0.5, 5.5, 10.5, and 15.5). The microbial composition and predicted metabolic functionality of the non-pregnant and pregnant gut was determined via sequencing of the variable 3 region of the 16S rRNA gene. Upon conception, differences in gut microbial communities were observed in both control and high fat-fed mice, including an increase in mucin-degrading bacteria. Control versus high fat-fed pregnant mice possessed the most profound changes to their maternal gut microbiota as indicated by statistically significant taxonomic differences. High fat-fed pregnant mice, when compared to control-fed animals, were found to be significantly enriched in microbes involved in metabolic pathways favoring fatty acid, ketone, vitamin, and bile synthesis. We show that pregnancy-induced changes in the female gut microbiota occur immediately at the onset of pregnancy, are vulnerable to modulation by diet, but are not dependent upon increases in maternal weight gain during pregnancy. High fat diet intake before and during pregnancy results in distinctive shifts in the pregnant gut microbiota in a gestational-age dependent manner and these shifts predict significant differences in the abundance of genes that favor lipid metabolism, glycolysis and gluconeogenic metabolic pathways over the course of pregnancy.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1080/19490976.2015.1086056

Cites

49 of 49 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Love, M. I., Huber, W., & Anders, S. (2014) · Genome Biology · doi:10.1186/s13059-014-0550-8 · Cited by 95,106
QIIME allows analysis of high-throughput community sequencing data
Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F. D., Costello, E. K., Fierer, N., Peña, A. G., Goodrich, J. K., Gordon, J. I., et al. (2010) · Nature Methods · doi:10.1038/nmeth.f.303 · Cited by 34,887
Cutadapt removes adapter sequences from high-throughput sequencing reads
Martin, M. (2011) · EMBnet.journal · doi:10.14806/ej.17.1.200 · Cited by 33,889
phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data
McMurdie, P. J., & Holmes, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061217 · Cited by 21,942
Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy
Wang, Q., Garrity, G. M., Tiedje, J. M., & Cole, J. R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00062-07 · Cited by 20,145
ggplot2: Elegant Graphics for Data Analysis
Wickham, H. (2009) · doi:10.1007/978-0-387-98141-3 · Cited by 14,447
An obesity-associated gut microbiome with increased capacity for energy harvest
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444
Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB
DeSantis, T. Z., Hugenholtz, P., Larsen, N., Rojas, M., Brodie, E. L., Keller, K., Huber, T., Dalevi, D., Hu, P., & Andersen, G. L. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.03006-05 · Cited by 10,891
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
Langille, M. G. I., Zaneveld, J., Caporaso, J. G., McDonald, D., Knights, D., Reyes, J. A., Clemente, J. C., Burkepile, D. E., Vega Thurber, R. L., Knight, R., et al. (2013) · Nature Biotechnology · doi:10.1038/nbt.2676 · Cited by 9,116
Obesity alters gut microbial ecology
Ley, R. E., Bäckhed, F., Turnbaugh, P., Lozupone, C. A., Knight, R. D., & Gordon, J. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504978102 · Cited by 6,176

Show all 51 references

Research works printed but not linked: 3

10.1113/jphysiol.2008.163477 · DOI
Harris K, 2012, J Obes, 2012, 14
Ye Y, 2011, Proc IEEE Int Conf Bioinformatics Biomed, 2010, 153

Sorted by citations

Gut microbiota and cardiovascular disease.
Witkowski, M., Weeks, T. L., & Hazen, S. L. (2020) · Circulation Research · doi:10.1161/circresaha.120.316242 · Cited by 1,051
From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways
Rogers, G. B., Keating, D. J., Young, R. L., Wong, M.-L., Licinio, J., & Wesselingh, S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.50 · Cited by 969
Microbial Changes during Pregnancy, Birth, and Infancy
Nuriel‐Ohayon, M., Neuman, H., & Koren, O. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01031 · Cited by 647
Multigroup analysis of compositions of microbiomes with covariate adjustments and repeated measures
Huang, L., & Peddada, S. (2023) · Nature Methods · doi:10.1038/s41592-023-02092-7 · Cited by 597
The role of the microbiome for human health: From basic science to clinical applications
Mohajeri, M. H., Brummer, R. J. M., Rastall, R. A., Weersma, R. K., Harmsen, H. J. M., Faas, M., & Eggersdorfer, M. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1703-4 · Cited by 440
The Association between Early-Life Gut Microbiota and Long-Term Health and Diseases
Sarkar, A., Yoo, J. Y., Dutra, S. V. O., Morgan, K. H., & Groer, M. E. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10030459 · Cited by 371
The role of the gut microbiota in development, function and disorders of the central nervous system and the enteric nervous system
Heiss, C. N., & Olofsson, L. E. (2019) · Journal of Neuroendocrinology · doi:10.1111/jne.12684 · Cited by 304
How biological sex of the host shapes its gut microbiota
Valeri, F., & Endres, K. (2021) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2021.100912 · Cited by 278
Maternal vertical transmission affecting early-life microbiota development
Wang, S., Ryan, C. A., Boyaval, P., Dempsey, E. M., Ross, R. P., & Stanton, C. (2020) · Trends in Microbiology · doi:10.1016/j.tim.2019.07.010 · Cited by 243
Short-Chain Fatty Acids, Maternal Microbiota and Metabolism in Pregnancy
Ziętek, M., Celewicz, Z., & Szczuko, M. (2021) · Nutrients · doi:10.3390/nu13041244 · Cited by 245
Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease
Codagnone, M. G., Spichak, S., O’Mahony, S. M., O’Leary, O. F., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.06.014 · Cited by 198
Diet-Gut Microbiota Interactions and Gestational Diabetes Mellitus (GDM)
Ponzo, V., Fedele, D., Goitre, I., Leone, F., Lezo, A., Monzeglio, C., Finocchiaro, C., Ghigo, E., & Bo, S. (2019) · Nutrients · doi:10.3390/nu11020330 · Cited by 158
Recent Insights on the Maternal Microbiota: Impact on Pregnancy Outcomes
Di Simone, N., Santamaria Ortiz, A., Specchia, M., Tersigni, C., Villa, P., Gasbarrini, A., Scambia, G., & D’Ippolito, S. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.528202 · Cited by 146
Factors influencing the gut microbiome in children: from infancy to childhood
Kumbhare, S. V., Patangia, D. V., Patil, R. H., Shouche, Y. S., & Patil, N. P. (2019) · Journal of Biosciences · doi:10.1007/s12038-019-9860-z · Cited by 143
The microbiota and autoimmunity: Their role in thyroid autoimmune diseases
Köhling, H.-L., Plummer, S. F., Marchesi, J. R., Davidge, K. S., & Ludgate, M. (2017) · Clinical Immunology · doi:10.1016/j.clim.2017.07.001 · Cited by 139
Microbial and metabolic alterations in gut microbiota of sows during pregnancy and lactation
Liu, H., Hou, C., Li, N., Zhang, X., Zhang, G., Yang, F., Zeng, X., Liu, Z., & Qiao, S. (2019) · The FASEB Journal · doi:10.1096/fj.201801221rr · Cited by 136
High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers
Gohir, W., Kennedy, K. M., Wallace, J. G., Saoi, M., Bellissimo, C. J., Britz‐McKibbin, P., Petrik, J., Surette, M. G., & Sloboda, D. M. (2019) · The Journal of Physiology · doi:10.1113/jp277353 · Cited by 133
Self-citation
The immune system and microbiome in pregnancy
Fuhler, G. M. (2020) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2020.101671 · Cited by 137
Effect of Probiotics on Metabolic Outcomes in Pregnant Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Taylor, B., Woodfall, G., Sheedy, K., O’Riley, M., Rainbow, K., Bramwell, E., & Kellow, N. J. (2017) · Nutrients · doi:10.3390/nu9050461 · Cited by 128
Systematic analysis of gut microbiota in pregnant women and its correlations with individual heterogeneity
Yang, H., Guo, R., Li, S., Liang, F., Cheng, T., Zhao, X., Long, Y., Liu, F., Jiang, M., Zhang, Y., et al. (2020) · npj Biofilms and Microbiomes · doi:10.1038/s41522-020-00142-y · Cited by 122
Infant gut microbiota colonization: influence of prenatal and postnatal factors, focusing on diet
Suárez-Martínez, C., Santaella, M., Yagüe‐Guirao, G., & Martínez‐Graciá, C. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1236254 · Cited by 128
The role of gut microbiota in the effects of maternal obesity during pregnancy on offspring metabolism
Zhou, L., & Xiao, X. (2017) · Bioscience Reports · doi:10.1042/bsr20171234 · Cited by 110
From Maternal Diet to Neurodevelopmental Disorders: A Story of Neuroinflammation
Bordeleau, M., de Cossío, L. F., Chakravarty, M. M., & Tremblay, M. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.612705 · Cited by 110
Obesity during pregnancy results in maternal intestinal inflammation, placental hypoxia, and alters fetal glucose metabolism at mid-gestation
Wallace, J. G., Bellissimo, C. J., Yeo, E., Xia, Y. F., Petrik, J., Surette, M. G., Bowdish, D. M. E., & Sloboda, D. M. (2019) · Scientific Reports · doi:10.1038/s41598-019-54098-x · Cited by 102
Self-citation
Culture-enriched metagenomic sequencing enables in-depth profiling of the cystic fibrosis lung microbiota
Whelan, F., Waddell, B. J. M., Syed, S. A., Shekarriz, S., Rabin, H. R., Parkins, M. D., & Surette, M. G. (2020) · Nature Microbiology · doi:10.1038/s41564-019-0643-y · Cited by 101
Self-citation
The Gut Microbiome and Female Health
Siddiqui, R., Makhlouf, Z., Alharbi, A. M., Alfahemi, H. H., & Khan, N. A. (2022) · Biology · doi:10.3390/biology11111683 · Cited by 111
The connection between microbiome and schizophrenia
Golofast, B., & Vales, K. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.12.011 · Cited by 92
The matter of the reproductive microbiome
Schoenmakers, S., Steegers‐Theunissen, R. P. M., & Faas, M. M. (2018) · Obstetric Medicine · doi:10.1177/1753495x18775899 · Cited by 91
Infections, genetic and environmental factors in pathogenesis of autoimmune thyroid diseases
Shukla, S. K., Singh, G., Ahmad, S., & Pant, P. (2018) · Microbial Pathogenesis · doi:10.1016/j.micpath.2018.01.004 · Cited by 86
Maternal Dietary Fiber Composition during Gestation Induces Changes in Offspring Antioxidative Capacity, Inflammatory Response, and Gut Microbiota in a Sow Model
Li, Y., Liu, H., Zhang, L., Yang, Y., Lin, Y., Zhuo, Y., Fang, Z., Che, L., Feng, B., Xu, S., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms21010031 · Cited by 89
The impact of obesity and hypercaloric diet consumption on anxiety and emotional behavior across the lifespan
Baker, K., Loughman, A., Spencer, S. J., & Reichelt, A. C. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.10.014 · Cited by 92
The microbiome in preterm birth
Chu, D. M., Seferovic, M. D., Pace, R. M., & Aagaard, K. M. (2018) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2018.03.006 · Cited by 84
Current evidence linking diet to gut microbiota and brain development and function
Ceppa, F., Mancini, A., & Tuohy, K. M. (2018) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2018.1462309 · Cited by 83
Maternal Microbiome and Infections in Pregnancy
Amir, M., Brown, J. A., Rager, S. L., Sanidad, K. Z., Ananthanarayanan, A., & Zeng, M. Y. (2020) · Microorganisms · doi:10.3390/microorganisms8121996 · Cited by 82
Michigan cohorts to determine associations of maternal pre-pregnancy body mass index with pregnancy and infant gastrointestinal microbial communities: Late pregnancy and early infancy
Sugino, K. Y., Paneth, N., & Comstock, S. S. (2019) · PLoS ONE · doi:10.1371/journal.pone.0213733 · Cited by 74
Maternal gut microbiota mediate intergenerational effects of high-fat diet on descendant social behavior
Gesù, C. M. D., Matz, L. M., Bolding, I. J., Fultz, R., Hoffman, K. L., Marino, A., Petrosino, J. F., & Buffington, S. A. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111461 · Cited by 74
Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis
Ovadia, C., Perdones-Montero, Á., Spagou, K., Smith, A., Sarafian, M. H., Gómez‐Romero, M., Bellafante, E., Clarke, L. C. D., Sadiq, F., Nikolova, V., et al. (2019) · Hepatology · doi:10.1002/hep.30661 · Cited by 73
Microbiota and Neurodevelopmental Trajectories: Role of Maternal and Early-Life Nutrition
Codagnone, M. G., Stanton, C., O’Mahony, S. M., Dinan, T. G., & Cryan, J. F. (2019) · Annals of Nutrition and Metabolism · doi:10.1159/000499144 · Cited by 74
Early-life programming of adipose tissue
Moreno‐Méndez, E., Quintero-Fabián, S., Fernández‐Mejía, C., & Lazo-de-la-Vega-Monroy, M.-L. (2020) · Nutrition Research Reviews · doi:10.1017/s0954422420000037 · Cited by 72
The Role of Microbiomes in Pregnant Women and Offspring: Research Progress of Recent Years
Yao, Y., Cai, X. T., Chen, C., Fang, H., Zhao, Y., Fei, W., Chen, F., & Zheng, C. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00643 · Cited by 62
Cellular and Molecular Pathophysiology of Gestational Diabetes
Torres‐Torres, J., Monroy-Muñoz, I. E., Duran, J. P., Solis‐Paredes, J. M., Camacho‐Martinez, Z. A., Baca, D., y Sosa, S. E., Martinez-Portilla, R. J., Rojas‐Zepeda, L., Borboa-Olivares, H. J., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252111641 · Cited by 77
Gut Microbiome Changes in Gestational Diabetes
Ionescu, R. F., Enache, R. M., Creţoiu, S. M., & Gașpar, B. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112839 · Cited by 69
Environmental enteric dysfunction: gut and microbiota adaptation in pregnancy and infancy
Cowardin, C. A., Syed, S., Iqbal, N. T., Jamil, Z., Sadiq, K., Iqbal, J., Ali, A., & Moore, S. R. (2022) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-022-00714-7 · Cited by 71
Microbial Mechanistic Insight into the Role of Inulin in Improving Maternal Health in a Pregnant Sow Model
Zhou, P., Zhao, Y., Zhang, P., Li, Y., Gui, T., Wang, J., Jin, C., Che, L., Li, J., Lin, Y., et al. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02242 · Cited by 63
The Effects of Synbiotic Supplementation on Pregnancy Outcomes in Gestational Diabetes
Karamali, M., Nasiri, N., Shavazi, N. T., Jamilian, M., Bahmani, F., Ebrahimi, M. T., & Asemi, Z. (2017) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-017-9313-7 · Cited by 65
Effect of L. acidophilus and B. lactis on blood glucose in women with gestational diabetes mellitus: a randomized placebo-controlled trial
Ebrahimi, F. S., Rad, A. H., Mosen, M., Abbasalizadeh, F., Tabrizi, A., & Khalili, L. (2019) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-019-0471-5 · Cited by 61
Microbiome Changes in Pregnancy Disorders
Giannella, L., Grelloni, C., Quintili, D., Fiorelli, A., Montironi, R., Alia, S., Carpini, G. D., Giuseppe, J. D., Vignini, A., & Ciavattini, A. (2023) · Antioxidants · doi:10.3390/antiox12020463 · Cited by 65
Microbiota of newborn meconium is associated with maternal anxiety experienced during pregnancy
Hu, J., Ly, J. J., Zhang, W., Huang, Y., Glover, V. A. S., Peter, I., Hurd, Y. L., & Nomura, Y. (2019) · Developmental Psychobiology · doi:10.1002/dev.21837 · Cited by 59
Antidepressant treatment with fluoxetine during pregnancy and lactation modulates the gut microbiome and metabolome in a rat model relevant to depression
Ramsteijn, A. S., Jašarević, E., Houwing, D. J., Bale, T. L., & Olivier, J. D. (2020) · Gut Microbes · doi:10.1080/19490976.2019.1705728 · Cited by 70
Effects of Probiotic Supplementation during Pregnancy on the Future Maternal Risk of Metabolic Syndrome
Obuchowska, A., Gorczyca, K., Standyło, A., Obuchowska, K., Kimber-Trojnar, Ż., Wierzchowska-Opoka, M., & Leszczyńska‐Gorzelak, B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158253 · Cited by 58
Stability of the vaginal, oral, and gut microbiota across pregnancy among African American women: the effect of socioeconomic status and antibiotic exposure
Dunlop, A. L., Knight, A. K., Satten, G. A., Cutler, A. J., Wright, M. L., Mitchell, R., Read, T. D., Mullé, J. G., Hertzberg, V., Hill, C. C., et al. (2019) · PeerJ · doi:10.7717/peerj.8004 · Cited by 60
Maternal obesity during pregnancy leads to derangements in one-carbon metabolism and the gut microbiota: implications for fetal development and offspring wellbeing
Rubini, E., Schenkelaars, N., Rousian, M., Sinclair, K. D., Wekema, L., Faas, M. M., Steegers‐Theunissen, R. P. M., & Schoenmakers, S. (2022) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2022.04.013 · Cited by 58
Maternal high fat diet and its consequence on the gut microbiome: A rat model
Mann, P. E., Huynh, K., & Widmer, G. (2017) · Gut Microbes · doi:10.1080/19490976.2017.1395122 · Cited by 53
Microbiota Induced Changes in the Immune Response in Pregnant Mice
Faas, M. M., Liu, Y., Borghuis, T., Bouwman, C. A., Harmsen, H. J. M., & de Vos, P. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02976 · Cited by 48
Early nutrition and gut microbiome: interrelationship between bacterial metabolism, immune system, brain structure, and neurodevelopment
Cerdó, T., Diéguez, E., & Campoy, C. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00188.2019 · Cited by 48
Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy
Ovadia, C., Perdones-Montero, Á., Fan, H. M., Mullish, B. H., McDonald, J. A. K., Papacleovoulou, G., Wahlstrom, A. M., Ståhlman, M., Tsakmaki, A., Clarke, L. C. D., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-60821-w · Cited by 48
Probiotics in the Prevention and Treatment of Gestational Diabetes Mellitus (GDM): A Review
Kamińska, K., Stenclik, D., Błażejewska, W., Bogdański, P., & Moszak, M. (2022) · Nutrients · doi:10.3390/nu14204303 · Cited by 52
Improvement of glucose metabolism in pregnant women through probiotic supplementation depends on gestational diabetes status: meta-analysis
Łagowska, K., Malinowska, A. M., Zawieja, B. E., & Zawieja, E. E. (2020) · Scientific Reports · doi:10.1038/s41598-020-74773-8 · Cited by 47
Relationships Between Perinatal Interventions, Maternal-Infant Microbiomes, and Neonatal Outcomes
Valentine, G. C., Chu, D. M., Stewart, C. J., & Aagaard, K. M. (2018) · Clinics in Perinatology · doi:10.1016/j.clp.2018.01.008 · Cited by 45
Effects of Probiotics on Glycemic Control and Metabolic Parameters in Gestational Diabetes Mellitus: Systematic Review and Meta-Analysis
Yefet, E., Bar, L., Izhaki, I., Iskander, R., Massalha, M., Younis, J. S., & Nachum, Z. (2023) · Nutrients · doi:10.3390/nu15071633 · Cited by 44
Postpartum depression: aetiology, pathogenesis and the role of nutrients and dietary supplements in prevention and management
Rupanagunta, G. P., Nandave, M., Rawat, D., Upadhyay, J., Rashid, S., & Ansari, M. N. (2023) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2023.05.008 · Cited by 67
High Fructose Intake During Pregnancy in Rats Influences the Maternal Microbiome and Gut Development in the Offspring
Astbury, S., Song, A., Zhou, M., Nielsen, B., Hoedl, A., Willing, B. P., Symonds, M. E., & Bell, R. C. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00203 · Cited by 44
Impact of Maternal Malnutrition on Gut Barrier Defense: Implications for Pregnancy Health and Fetal Development
Srugo, S. A., Bloise, E., Nguyen, T. T.-T. N., & Connor, K. L. (2019) · Nutrients · doi:10.3390/nu11061375 · Cited by 48
An Insight into Probiotics Bio-Route: Translocation from the Mother’s Gut to the Mammary Gland
Selvamani, S., Dailin, D. J., Gupta, V. K., Wahid, M., Keat, H. C., Natasya, K. H., Malek, R. A., Haque, S., Sayyed, R. Z., Abomoelak, B., et al. (2021) · Applied Sciences · doi:10.3390/app11167247 · Cited by 45
Gut microbiota and probiotic intervention as a promising therapeutic for pregnant women with cardiometabolic disorders: Present and future directions
Alves, J. L. D. B., de Oliveira, Y., Carvalho, N., Cavalcante, R. G. S., Lira, M. M. P., do Nascimento, L. C. P., Magnani, M., Vidal, H., Braga, V. A., & de Souza, E. L. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.104252 · Cited by 43
Gut microbiota in pregnant Malaysian women: a comparison between trimesters, body mass index and gestational diabetes status
Abdullah, B., Daud, S., Aazmi, M. S., Idorus, M. Y., & Mahamooth, M. I. J. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-04472-x · Cited by 40
Nutrition during pregnancy: Influence on the gut microbiome and fetal development
Barrientos, G., Ronchi, F., & Conrad, M. L. (2023) · American Journal of Reproductive Immunology · doi:10.1111/aji.13802 · Cited by 42
Associations of prenatal exposure to polybrominated diphenyl ethers and polychlorinated biphenyls with long-term gut microbiome structure: a pilot study
Laue, H. E., Brennan, K. J. M., Gillet, V., Abdelouahab, N., Coull, B. A., Weisskopf, M. G., Burris, H. H., Zhang, W., Takser, L., & Baccarelli, A. (2019) · Environmental Epidemiology · doi:10.1097/ee9.0000000000000039 · Cited by 37
Gut microbial communities from patients with anorexia nervosa do not influence body weight in recipient germ-free mice
Glenny, E. M., Fouladi, F., Thomas, S., Bulik‐Sullivan, E. C., Tang, Q., Djukic, Z., Trillo-Ordonez, Y. S., Fodor, A. A., Tarantino, L. M., Bulik, C. M., et al. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1897216 · Cited by 37
Maternal microbiota and gestational diabetes: impact on infant health
Singh, P., Elhag, D. A., Ibrahim, I., Abdullahi, H., & Khodor, S. A. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04230-3 · Cited by 41
Gut microbiota promotes immune tolerance at the maternal-fetal interface
Brown, J. A., Amir, M., Yu, S., Wong, D. S. H., Gu, J., Balaji, U., Parkhurst, C. N., Hong, S., Hart, L. R., Carrow, H. C., et al. (2025) · Cell · doi:10.1016/j.cell.2025.11.022 · Cited by 35
Factors Influencing Neonatal Gut Microbiome and Health with a Focus on Necrotizing Enterocolitis
Beharry, K. D. A., Latkowska, M., Valencia, A. M., Allana, A., Soto, J., Cai, C. L., GOLOMBEK, S. G., Hand, I. L., & Aranda, J. V. (2023) · Microorganisms · doi:10.3390/microorganisms11102528 · Cited by 39
The effects of gut microbiota on metabolic outcomes in pregnant women and their offspring
Lv, Y., Yan, Z., Zhao, X. Y., Gang, X., He, G., Sun, L., Li, Z., & Wang, G. (2018) · Food & Function · doi:10.1039/c8fo00601f · Cited by 36
Microbiome and Gestational Diabetes: Interactions with Pregnancy Outcome and Long-Term Infant Health
Neri, C., Serafino, E., Morlando, M., & Familiari, A. (2021) · Journal of Diabetes Research · doi:10.1155/2021/9994734 · Cited by 37
Bile acids and microbes in metabolic disease
Sah, D. K., Arjunan, A., Park, S. Y., & Jung, Y. D. (2022) · World Journal of Gastroenterology · doi:10.3748/wjg.v28.i48.6846 · Cited by 34
Reemergence of Lower-Airway Microbiota in Lung Transplant Patients with Cystic Fibrosis
Syed, S. A., Whelan, F., Waddell, B. J. M., Rabin, H. R., Parkins, M. D., & Surette, M. G. (2016) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201606-431oc · Cited by 31
Self-citation
The Maternal Microbiome and Gestational Diabetes Mellitus: Cause and Effect
Dias, S. C., Pheiffer, C., & Adam, S. (2023) · Microorganisms · doi:10.3390/microorganisms11092217 · Cited by 35
Early Life Microbiota Colonization at Six Months of Age: A Transitional Time Point
Raspini, B., Vacca, M., Porri, D., Giuseppe, R. D., Calabrese, F. M., Chieppa, M., Liso, M., Cerbo, R. M., Civardi, E., Garofoli, F., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.590202 · Cited by 36
Vertical transmission of gut microbiota: Points of action of environmental factors influencing brain development
Tochitani, S. (2020) · Neuroscience Research · doi:10.1016/j.neures.2020.11.006 · Cited by 30
Maternal Phlorizin Intake Protects Offspring from Maternal Obesity-Induced Metabolic Disorders in Mice via Targeting Gut Microbiota to Activate the SCFA-GPR43 Pathway
Mei, X., Li, Y., Zhang, X., Zhai, X., Yang, Y., Li, Z., & Li, L. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c06370 · Cited by 30
Exercise improves metabolic function and alters the microbiome in rats with gestational diabetes
Mahizir, D., Briffa, J. F., Wood, J. L., Anevska, K., Hill‐Yardin, E. L., Jefferies, A. J., Gravina, S., Mazzarino, G., Franks, A. E., Moritz, K. M., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201901424r · Cited by 29
Fecal microbiota of different reproductive stages of the central population of the lesser-long nosed bat, Leptonycteris yerbabuenae
Gaona, O., Gómez-Acata, S., Cerqueda‐García, D., Neri-Barrios, C. X., & Falcón, L. I. (2019) · PLoS ONE · doi:10.1371/journal.pone.0219982 · Cited by 29
Determination of the changes on the small intestine of pregnant mice by histological, enzyme histochemical, and immunohistochemical methods
Şensoy, E., & Öznurlu, Y. (2019) · The Turkish Journal of Gastroenterology · doi:10.5152/tjg.2019.18681 · Cited by 28
Shift of Maternal Gut Microbiota of Tibetan Antelope (Pantholops hodgsonii) During the Periparturition Period
Shi, Y., Miao, Z., Su, J., & Wasser, S. K. (2021) · Current Microbiology · doi:10.1007/s00284-020-02339-y · Cited by 29
Impact of Ethanol and Saccharin on Fecal Microbiome in Pregnant and Non-Pregnant Mice
Labrecque, M. T., Malone, D., & Allan, C. A. M. (2015) · Journal of Pregnancy and Child Health · doi:10.4172/2376-127x.1000193 · Cited by 28
Preconception helminth infection alters offspring microbiota and immune subsets in a mouse model
Nyangahu, D. D., Darby, M., Havyarimana, E., Brown, B. P., Horsnell, W. G. C., & Jaspan, H. B. (2020) · Parasite Immunology · doi:10.1111/pim.12721 · Cited by 27
Role of Maternal Microbiota and Nutrition in Early-Life Neurodevelopmental Disorders
Daliry, A., & Pereira, E. N. G. D. S. (2021) · Nutrients · doi:10.3390/nu13103533 · Cited by 31
The murine female intestinal microbiota does not shift throughout the estrous cycle
Wallace, J. G., Potts, R., Szamosi, J. C., Surette, M. G., & Sloboda, D. M. (2018) · PLoS ONE · doi:10.1371/journal.pone.0200729 · Cited by 27
Self-citation
The role of short-chain fatty acids produced by gut microbiota in the regulation of pre-eclampsia onset
Cui, J., Wang, J., & Wang, Y. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1177768 · Cited by 30
Changes in intestinal gene expression and microbiota composition during late pregnancy are mouse strain dependent
Elderman, M. E., Hugenholtz, F., Belzer, C., Boekschoten, M. V., de Haan, B., de Vos, P., & Faas, M. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-28292-2 · Cited by 26
Evaluation of gut bacterial community composition and antimicrobial resistome in pregnant and non-pregnant women from Saudi population
Khan, I., Yasir, M., Farman, M., Kumosani, T., AlBasri, S. F., Bajouh, O. S., & Azhar, E. I. (2019) · Infection and Drug Resistance · doi:10.2147/idr.s200213 · Cited by 25
Recent advances of intestinal microbiota transmission from mother to infant
Yang, L., Sakandar, H. A., Sun, Z., & Zhang, H. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104719 · Cited by 28
Host–gut microbiota interactions during pregnancy
Amato, K. R., Pradhan, P. P., Mallott, E. K., Shirola, W., & Lu, A. (2024) · Evolution Medicine and Public Health · doi:10.1093/emph/eoae001 · Cited by 28
Milk fat globule membrane supplementation to obese rats during pregnancy and lactation promotes neurodevelopment in offspring via modulating gut microbiota
Yuan, Q., Gong, H., Du, ‬., Li, T., & Mao, X. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.945052 · Cited by 24
Dietary Influence on the Dynamics of the Human Gut Microbiome: Prospective Implications in Interventional Therapies
Adithya, K. K., Rajeev, R., Selvin, J., & Kiran, G. S. (2021) · ACS Food Science & Technology · doi:10.1021/acsfoodscitech.0c00075 · Cited by 23
The role of probiotic intervention in regulating gut microbiota, short-chain fatty acids and depression-like behavior in lead-exposed rats
Chen, X., Meng, S., Yu, Y., Li, S., Wu, L., & Zhang, Y. (2022) · International Journal of Occupational Medicine and Environmental Health · doi:10.13075/ijomeh.1896.01795 · Cited by 22
Gut Microbiota and Critical Metabolites: Potential Target in Preventing Gestational Diabetes Mellitus?
Hu, R., Liu, Z., Geng, Y., Huang, Y., Li, F., Dong, H., Ma, W., Song, K., Zhang, M., & Song, Y. (2023) · Microorganisms · doi:10.3390/microorganisms11071725 · Cited by 23
Association between Probiotic Yogurt Intake and Gestational Diabetes Mellitus: A Case-Control Study
Xiaoqian, C. H. E. N., Jiang, X., Huang, X., He, H.-G., & Zheng, J. (2020) · Iranian Journal of Public Health · doi:10.18502/ijph.v48i7.2946 · Cited by 22
The microbiome as a modulator of neurological health across the maternal-offspring interface
Orchanian, S. B., & Hsiao, E. Y. (2025) · Journal of Clinical Investigation · doi:10.1172/jci184314 · Cited by 23
A role for the microbiome in mother–infant interaction and perinatal depression
Sanders, A., Rackers, H., & Kimmel, M. (2019) · International Review of Psychiatry · doi:10.1080/09540261.2018.1548431 · Cited by 21

Authors: Gohir, W., Whelan, F. J., Surette, M. G., Moore, C., Schertzer, J. D., & Sloboda, D. M.
Affiliations: McMaster University (CA)
Corresponding author: Sloboda, Deborah M
ORCID: Whelan, Fiona J
Surette, Michael G
Schertzer, Jonathan D
Sloboda, Deborah M
Venue: Gut Microbes
Publisher: Informa UK Limited
Published: 2015-08-31
Volume: 6
Issue: 5
Pages: 310-320
ISSN: 1949-0976 (ISSN-L)
1949-0984
DOI: 10.1080/19490976.2015.1086056
PMC: PMC4826136
OpenAlex: W2168621640
Cited by: 203
References: 51
Citations by year: 2026: 13 · 2025: 15 · 2024: 18 · 2023: 26 · 2022: 21 · 2021: 23 · 2020: 21 · 2019: 32 · 2018: 16 · 2017: 13 · 2016: 4 · 2015: 1
FWCI: 4.92
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Gut Microbes (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Repository@Nottingham (University of Nottingham) (submittedVersion, cc-by)
Repository@Nottingham (University of Nottingham) (submittedVersion)
Research Explorer (The University of Manchester) (submittedVersion, other-oa)
Funders: University of Manitoba
Canadian Institutes of Health Research
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Keywords: maternal gut microbiota, pregnancy, high-fat diet, gut microbiota composition, mucin-degrading bacteria, gestational weight gain, gestational age, lipid metabolism, glycolysis, gluconeogenesis, ketone body metabolism, vitamin metabolism, C57BL/6 mice
MeSH terms: Gastrointestinal Microbiome, Animals, Diet, DNA, Ribosomal, Feces, Female, Mice, Inbred C57BL, Pregnancy, RNA, Ribosomal, 16S, Sequence Analysis, DNA

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Pregnancy-related changes in the maternal gut microbiota are dependent upon the mother's periconceptional diet

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks