The yeast cell-wall salvage pathway

Popolo, L.; Gualtieri, T.; Ragni, E.

doi:10.1080/mmy.39.1.111.121

Cited by 142Fungal and yeast genetics researchAntifungal resistance and susceptibilityFungal Infections and Studies

The yeast cell-wall salvage pathway

Popolo, L., Gualtieri, T., Ragni, E.·2001·Medical Mycology

DOI 10.1080/mmy.39.1.111.121

Open this paper in CoChat — free account

Abstract

The integrity of the cell wall depends on the synthesis and correct assembly of its individual components. Several environmental factors, such as temperature up-shift, treatments with mating factors or with specific cell wall-perturbing drugs, or genetic factors, such as inactivation of cell wall-related genes (for example FKS1 or GAS1) can impair construction of the cell wall. As the cell wall is essential for preserving the osmotic integrity of the cell, several responses are triggered in response to cell-wall damage. This review focuses on the activation of salvage pathways that guarantee cell survival through remodeling of the extracellular matrix. These researches have useful implication for the study of similar pathways in human fungal pathogens, and for the evaluation of the efficacy of new antifungal drugs.

Integrity signals

Registry

Crossref · 10.1080/mmy.39.1.111.121

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Our functional analyses demonstrate that CHS3 is crucial during hyphal growth in the absence of Phr1p.
“Our functional analyses demonstrate that CHS3 is crucial during hyphal growth in the absence of Phr1p and support the notion that Chs3p is the major compensatory chitin synthase both in cell wall stress and HWS in fungi [21, 28, 47, 62, 63].”
From Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling (2016) · cites this paper as [62]
Chs3p is the major compensatory chitin synthase both in cell wall stress and HWS in fungi.
“Our functional analyses demonstrate that CHS3 is crucial during hyphal growth in the absence of Phr1p and support the notion that Chs3p is the major compensatory chitin synthase both in cell wall stress and HWS in fungi [21, 28, 47, 62, 63].”
From Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling (2016) · cites this paper as [62]

MAP Kinase Pathways in the YeastSaccharomyces cerevisiae
Gustin, M., Albertyn, J., Alexander, M., & Davenport, K. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1264-1300.1998 · Cited by 1,010 · see citing works
Genome‐wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathway
Jung, U. S., & Levin, D. E. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01667.x · Cited by 424 · see citing works
A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae
Verna, J., Lodder, A., Lee, K., Vagts, A. J., & Ballester, R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.25.13804 · Cited by 366 · see citing works
Glycosylphosphatidylinositol-anchored Glucanosyltransferases Play an Active Role in the Biosynthesis of the Fungal Cell Wall
Mouyna, I., Fontaine, T., Vai, M., Monod, M., Fonzi, W. A., Diaquin, M., Popolo, L., Hartland, R. P., & Latgé, J.-P. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.20.14882 · Cited by 353 · see citing works
Self-citation
The Yeast Cell Wall and Septum as Paradigms of Cell Growth and Morphogenesis
Cabib, E., Roh, D.-H., Schmidt, M., Crotti, L. B., & Varma, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.r000031200 · Cited by 344 · see citing works
Regulatory Mechanisms for Modulation of Signaling through the Cell Integrity Slt2-mediated Pathway in Saccharomyces cerevisiae
Martı́n, H., Rodrı́guez-Pachón, J. M., Ruiz, C., Nombela, C., & Molina, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.2.1511 · Cited by 343 · see citing works
Spatial regulation of the exocyst complex by Rho1 GTPase
Guo, W., Tamanoi, F., & Novick, P. (2001) · Nature Cell Biology · doi:10.1038/35070029 · Cited by 327 · see citing works
The protein kinase C‐mediated MAP kinase pathway involved in the maintenance of cellular integrity in Saccharomyces cerevisiae
Heinisch, J. J., Lorberg, A., Schmitz, H., & Jacoby, J. J. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01375.x · Cited by 322 · see citing works
Wsc1 and Mid2 Are Cell Surface Sensors for Cell Wall Integrity Signaling That Act through Rom2, a Guanine Nucleotide Exchange Factor for Rho1
Philip, B., & Levin, D. E. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.1.271-280.2001 · Cited by 304 · see citing works
A new approach for isolating cell wall mutants in Saccharomyces cerevisiae by screening for hypersensitivity to calcofluor white
Ram, A. F. J., Wolters, A., ten Hoopen, R., & Klis, F. M. (1994) · Yeast · doi:10.1002/yea.320100804 · Cited by 300 · see citing works
Cell Wall Stress Depolarizes Cell Growth via Hyperactivation of Rho1
Delley, P.-A., & Hall, M. N. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.1.163 · Cited by 300 · see citing works
Signalling in the Yeasts: An Informational Cascade with Links to the Filamentous Fungi
Banuett, F. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.2.249-274.1998 · Cited by 297 · see citing works
The riddle of MAP kinase signaling specificity
Madhani, H. D., & Fink, G. R. (1998) · Trends in Genetics · doi:10.1016/s0168-9525(98)01425-5 · Cited by 293 · see citing works
Cell wall perturbation in yeast results in dual phosphorylation of the Slt2/Mpk1 MAP kinase and in an Slt2-mediated increase in FKS2–lacZ expression, glucanase resistance and thermotolerance
de Nobel, H., Ruiz, C., Martı́n, H., Morris, W. L., Brul, S., Molina, M., & Klis, F. M. (2000) · Microbiology · doi:10.1099/00221287-146-9-2121 · Cited by 269 · see citing works
Coordinated regulation of gene expression by the cell cycle transcription factor Swi4 and the protein kinase C MAP kinase pathway for yeast cell integrity.
Igual, J. C., Johnson, A. L., & Johnston, L. H. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00880.x · Cited by 264 · see citing works
PHR1 , a pH-Regulated Gene of Candida albicans , is Required for Morphogenesis
Saporito-Irwin, S. M., Birse, C. E., Sypherd, P. S., & Fonzi, W. A. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.2.601 · Cited by 264 · see citing works
Saccharomyces cerevisiae Mid2p Is a Potential Cell Wall Stress Sensor and Upstream Activator of the PKC1-MPK1 Cell Integrity Pathway
Ketela, T., Green, R., & Bussey, H. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.11.3330-3340.1999 · Cited by 263 · see citing works
The pH of the Host Niche Controls Gene Expression in and Virulence of Candida albicans
De Bernardis, F., Mühlschlegel, F. A., Cassone, A., & Fonzi, W. A. (1998) · Infection and Immunity · doi:10.1128/iai.66.7.3317-3325.1998 · Cited by 258 · see citing works
Increase in chitin as an essential response to defects in assembly of cell wall polymers in the ggp1delta mutant of Saccharomyces cerevisiae
Popolo, L., Gilardelli, D., Bonfante, P., & Vai, M. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.2.463-469.1997 · Cited by 226 · see citing works
Self-citation
A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator
Gray, J. V., Ogas, J. P., Kamada, Y., Stone, M., Levin, D. E., & Herskowitz, I. (1997) · The EMBO Journal · doi:10.1093/emboj/16.16.4924 · Cited by 224 · see citing works
MID1, a novel Saccharomyces cerevisiae gene encoding a plasma membrane protein, is required for Ca2+ influx and mating.
Iida, H., Nakamura, H., Ono, T., Okumura, M. S., & Anraku, Y. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.12.8259 · Cited by 218 · see citing works
Molecular Identification of a Eukaryotic, Stretch-Activated Nonselective Cation Channel
Kanzaki, M., Nagasawa, M., Kojima, I., Sato, C., Naruse, K., Sokabe, M., & Iida, H. (1999) · Science · doi:10.1126/science.285.5429.882 · Cited by 213 · see citing works
A Homolog of Voltage-Gated Ca 2+ Channels Stimulated by Depletion of Secretory Ca 2+ in Yeast
Locke, E. G., Bonilla, M., Liang, L., Takita, Y., & Cunningham, K. W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.18.6686-6694.2000 · Cited by 212 · see citing works
PHR2 of Candida Albicans Encodes a Functional Homolog of the pH-regulated Gene PHR1 with an Inverted Pattern of pH-Dependent Expression
Mühlschlegel, F. A., & Fonzi, W. A. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.10.5960 · Cited by 209 · see citing works
Temperature-Induced Expression of Yeast FKS2 Is under the Dual Control of Protein Kinase C and Calcineurin
Zhao, C., Jung, U. S., Garrett-Engele, P., Roe, T., Cyert, M. S., & Levin, D. E. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.2.1013 · Cited by 209 · see citing works
Loss of the Plasma Membrane-Bound Protein Gas1p in Saccharomyces cerevisiae Results in the Release of β1,3-Glucan into the Medium and Induces a Compensation Mechanism To Ensure Cell Wall Integrity
Ram, A. F. J., Kapteyn, J. C., Montijn, R. C., Caro, L. H. P., Douwes, J. E., Baginsky, W., Mazur, P., van den Ende, H., & Klis, F. M. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.6.1418-1424.1998 · Cited by 200 · see citing works
Cell wall integrity modulates RHO1 activity via the exchange factor ROM2
Bickle, M., Delley, P., Schmidt, A., & Hall, M. N. (1998) · EMBO Journal · doi:10.1093/emboj/17.8.2235 · Cited by 198 · see citing works
Mid2 Is a Putative Sensor for Cell Integrity Signaling in Saccharomyces cerevisiae
Rajavel, M., Philip, B., Buehrer, B. M., Errede, B., & Levin, D. E. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.3969 · Cited by 194 · see citing works
PHR1 and PHR2 of Candida albicans Encode Putative Glycosidases Required for Proper Cross-Linking of β-1,3- and β-1,6-Glucans
Fonzi, W. A. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.22.7070-7079.1999 · Cited by 193 · see citing works
A Homolog of Mammalian, Voltage-Gated Calcium Channels Mediates Yeast Pheromone-Stimulated Ca 2+ Uptake and Exacerbates the cdc1 (Ts) Growth Defect
Paidhungat, M., & Garrett, S. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.11.6339 · Cited by 191 · see citing works
Characterization of a Serum Response Factor-Like Protein in Saccharomyces cerevisiae , Rlm1, Which Has Transcriptional Activity Regulated by the Mpk1 (Slt2) Mitogen-Activated Protein Kinase Pathway
Watanabe, Y., Takaesu, G., Hagiwara, M., Irie, K., & Matsumoto, K. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.5.2615 · Cited by 191 · see citing works
Calcineurin, the Ca2+/Calmodulin-Dependent Protein Phosphatase, Is Essential in Yeast Mutants with Cell Integrity Defects and in Mutants That Lack a Functional Vacuolar H+-Atpase
Garrett-Engele, P. W., Moilanen, B., & Cyert, M. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.8.4103 · Cited by 187 · see citing works
The Gas1 glycoprotein, a putative wall polymer cross-linker
Popolo, L., & Vai, M. (1999) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(98)00138-x · Cited by 185 · see citing works
Self-citation
Altered extent of cross-linking of beta1,6-glucosylated mannoproteins to chitin in Saccharomyces cerevisiae mutants with reduced cell wall beta1,3-glucan content
Kapteyn, J. C., Ram, A. F. J., Groos, E. M., KOLLÁR, R., Montijn, R. C., ENDE, H. V. D., Llobell, A., Cabib, E., & Klis, F. M. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.20.6279-6284.1997 · Cited by 181 · see citing works
Yeast Respond to Hypotonic Shock with a Calcium Pulse
Batiza, A. F., Schulz, T., & Masson, P. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.38.23357 · Cited by 178 · see citing works
The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components
Lee, B. N., & Elion, E. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.22.12679 · Cited by 156 · see citing works
The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton
Helliwell, S. B., Schmidt, A., Ohya, Y., & Hall, M. N. (1998) · Current Biology · doi:10.1016/s0960-9822(07)00511-8 · Cited by 156 · see citing works
Coordination of the Mating and Cell Integrity Mitogen-Activated Protein Kinase Pathways in Saccharomyces cerevisiae
Buehrer, B. M., & Errede, B. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.11.6517 · Cited by 141 · see citing works
Defects in Protein Glycosylation Cause SHO1-Dependent Activation of a STE12 Signaling Pathway in Yeast
Cullen, P. J., Schultz, J., Horecka, J., Stevenson, B. J., Jigami, Y., & Sprague, G. F. (2000) · Genetics · doi:10.1093/genetics/155.3.1005 · Cited by 118 · see citing works
A Novel β-( , , )-Glucanosyltransferase from the Cell Wall of Aspergillus fumigatus
Hartland, R. P., Fontaine, T., Debeaupuis, J. P., Simenel, C., Delepierre, M., & Latgé, J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.43.26843 · Cited by 117 · see citing works
Physiological analysis of mutants indicates involvement of the Saccharomyces cerevisiae GPI-anchored protein gp115 in morphogenesis and cell separation
Popolo, L., Vai, M., Gatti, E., Porello, S. L., Bonfante, P., Balestrini, R., & Alberghina, L. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.7.1879-1885.1993 · Cited by 113 · see citing works
Self-citation
A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene
Jacoby, J. J., Nilius, S. M., & Heinisch, J. J. (1998) · Molecular and General Genetics MGG · doi:10.1007/s004380050717 · Cited by 104 · see citing works
Chitin Synthesis in a gas1 Mutant of Saccharomyces cerevisiae
Valdivieso, M.-H., Ferrario, L., Vai, M., Duran, A., & Popolo, L. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.17.4752-4757.2000 · Cited by 89 · see citing works
Self-citation
Characterization of the chitin biosynthesis process as a compensatory mechanism in the fks1 mutant of Saccharomyces cerevisiae
García‐Rodríguez, L. J., Trilla, J. A., Castro, C., Valdivieso, M. ‐., Durán, A., & Roncero, C. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01835-4 · Cited by 89 · see citing works
Up-regulation of genes encoding glycosylphosphatidylinositol (GPI)-attached proteins in response to cell wall damage caused by disruption of FKS1 in Saccharomyces cerevisiae
Terashima, H., Yabuki, N., Arisawa, M., Hamada, K., & Kitada, K. (2000) · Molecular and General Genetics MGG · doi:10.1007/s004380000285 · Cited by 85 · see citing works
Chitin synthase III: Synthetic lethal mutants and “stress related” chitin synthesis that bypasses the CSD3/CHS6 localization pathway
Osmond, B. C., Specht, C. A., & Robbins, P. W. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11206 · Cited by 66 · see citing works
Calcineurin-dependent growth of an FK506- and CsA-hypersensitive mutant of Saccharomyces cerevisiae
Parent, S. A., NIELSEN, J. B. K., Morin, N. R., Chrebet, G. L., Ramadan, N., Dahl, A. M., Hsu, M. J., Bostian, K. A., & Foor, F. (1993) · Journal of General Microbiology · doi:10.1099/00221287-139-12-2973 · Cited by 62 · see citing works
The MID2 gene encodes a putative integral membrane protein with a Ca2+-binding domain and shows mating pheromone-stimulated expression in Saccharomyces cerevisiae
Ono, T., Suzuki, T., Anraku, Y., & Iida, H. (1994) · Gene · doi:10.1016/0378-1119(94)90657-2 · Cited by 54 · see citing works
Defects in Assembly of the Extracellular Matrix Are Responsible for Altered Morphogenesis of a Candida albicans phr1 Mutant
Popolo, L., & Vai, M. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.1.163-166.1998 · Cited by 41 · see citing works
Self-citation
Increase of External Osmolarity Reduces Morphogenetic Defects and Accumulation of Chitin in a gas1 Mutant of Saccharomyces cerevisiae
Turchini, A., Ferrario, L., & Popolo, L. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.4.1167-1171.2000 · Cited by 23 · see citing works
Self-citation
Molecular responses to changes in the environmental pH are conserved between the fungal pathogens Candida dubliniensis and Candida albicans
Heinz, W., Kurzai, O., Brakhage, A. A., Fonzi, W. A., Korting, H. C., Frosch, M., & Mühlschlegel, F. A. (2000) · International Journal of Medical Microbiology · doi:10.1016/s1438-4221(00)80120-4 · Cited by 19 · see citing works

Flagged first, then by citations

Sorted by citations

The Fungal Cell Wall: Structure, Biosynthesis, and Function
Gow, N. A. R., Latge, J.-P., & Munro, C. A. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.funk-0035-2016 · Cited by 1,423 · see citing works
Echinocandin antifungal drugs
Denning, D. W. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14472-8 · Cited by 1,131 · see citing works
Dynamics of cell wall structure in Saccharomyces cerevisiae
Klis, F. M., Mol, P. C., Hellingwerf, K. J., & Brul, S. (2002) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2002.tb00613.x · Cited by 1,007 · see citing works
Candidiasis and Mechanisms of Antifungal Resistance
Bhattacharya, S., Sae-Tia, S., & Fries, B. C. (2020) · Antibiotics · doi:10.3390/antibiotics9060312 · Cited by 474 · see citing works
Architecture of the dynamic fungal cell wall
Gow, N. A. R., & Lenardon, M. D. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00796-9 · Cited by 447 · see citing works
Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins
Walker, L. A., Munro, C. A., de Bruijn, I., Lenardon, M. D., McKinnon, A., & Gow, N. A. R. (2008) · PLoS Pathogens · doi:10.1371/journal.ppat.1000040 · Cited by 445 · see citing works
The Global Transcriptional Response to Transient Cell Wall Damage in Saccharomyces cerevisiae and Its Regulation by the Cell Integrity Signaling Pathway
García, R., Bermejo, C., Grau, C., Pérez, R., Rodríguez-Peña, J. M., Francois, J., Nombela, C., & Arroyo, J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312954200 · Cited by 338 · see citing works
The PKC, HOG and Ca 2+ signalling pathways co‐ordinately regulate chitin synthesis in Candida albicans
Munro, C. A., Selvaggini, S., De Bruijn, I., Walker, L., Lenardon, M. D., Gerssen, B., Milne, S., Brown, A. J. P., & Gow, N. A. R. (2007) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.05588.x · Cited by 309 · see citing works
Cell wall glucans of fungi. A review
Ruíz-Herrera, J., & Ortiz‐Castellanos, L. (2019) · The Cell Surface · doi:10.1016/j.tcsw.2019.100022 · Cited by 308 · see citing works
Proteomic Analysis of Extracellular Proteins from Aspergillus oryzae Grown under Submerged and Solid-State Culture Conditions
Oda, K., Kakizono, D., Yamada, O., Iefuji, H., Akita, O., & Iwashita, K. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.5.3448-3457.2006 · Cited by 267 · see citing works
Genome-wide Analysis of the Response to Cell Wall Mutations in the Yeast Saccharomyces cerevisiae
Lagorce, A., Hauser, N. C., Labourdette, D., Rodriguez, C., Martin-Yken, H., Arroyo, J., Hoheisel, J. D., & François, J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211604200 · Cited by 254 · see citing works
Functional analysis of Candida albicans GPI-anchored proteins: Roles in cell wall integrity and caspofungin sensitivity
Plaine, A., Walker, L., Da Costa, G., Mora-Montes, H. M., McKinnon, A., Gow, N. A. R., Gaillardin, C., Munro, C. A., & Richard, M. L. (2008) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2008.08.003 · Cited by 238 · see citing works
Elevated Chitin Content Reduces the Susceptibility of Candida Species to Caspofungin
Walker, L. A., Gow, N. A. R., & Munro, C. A. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01486-12 · Cited by 214 · see citing works
Sentinels at the wall: cell wall receptors and sensors
Humphrey, T., Bonetta, D. T., & Goring, D. R. (2007) · New Phytologist · doi:10.1111/j.1469-8137.2007.02192.x · Cited by 211 · see citing works
Elevated Cell Wall Chitin in Candida albicans Confers Echinocandin Resistance In Vivo
Lee, K. K., MacCallum, D. M., Jacobsen, M. D., Walker, L. A., Odds, F. C., Gow, N. A. R., & Munro, C. A. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00683-11 · Cited by 209 · see citing works
Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae.
Agarwal, A. K., Rogers, P. D., Baerson, S. R., Jacob, M. R., Barker, K. S., Cleary, J. D., Walker, L. A., Nagle, D. G., & Clark, A. M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306291200 · Cited by 204 · see citing works
The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress
Bermejo, C., Rodríguez, E., García, R., Rodríguez-Peña, J. M., Rodríguez de la Concepción, M. L., Rivas, C., Arias, P., Nombela, C., Posas, F., & Arroyo, J. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-08-0742 · Cited by 204 · see citing works
Mnt1p and Mnt2p of Candida albicans Are Partially Redundant α-1,2-Mannosyltransferases That Participate in O-Linked Mannosylation and Are Required for Adhesion and Virulence
Munro, C. A., Bates, S., Buurman, E. T., Hughes, H. B., MacCallum, D. M., Bertram, G., Atrih, A., Ferguson, M. A. J., Bain, J. M., Brand, A., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m411413200 · Cited by 200 · see citing works
Molecular Mechanisms Associated with Antifungal Resistance in Pathogenic Candida Species
Czajka, K. M., Venkataraman, K., Brabant-Kirwan, D., Santi, S. A., Verschoor, C. P., Appanna, V. D., Singh, R. I., Saunders, D., & Tharmalingam, S. (2023) · Cells · doi:10.3390/cells12222655 · Cited by 196 · see citing works
The fungal cell wall as a target for the development of new antifungal therapies
Cortés, J. C. G., Curto, M.-Á., Carvalho, V. S. D., Pérez, P., & Ribas, J. C. (2019) · Biotechnology Advances · doi:10.1016/j.biotechadv.2019.02.008 · Cited by 172 · see citing works
The High Osmotic Response and Cell Wall Integrity Pathways Cooperate to Regulate Transcriptional Responses to Zymolyase-induced Cell Wall Stress in Saccharomyces cerevisiae
García, R., Rodríguez-Peña, J. M., Bermejo, C., Nombela, C., & Arroyo, J. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808693200 · Cited by 165 · see citing works
Two Components of a velvet -Like Complex Control Hyphal Morphogenesis, Conidiophore Development, and Penicillin Biosynthesis in Penicillium chrysogenum
Hoff, B., Kamerewerd, J., Sigl, C., Mitterbauer, R., Zadra, I., Kürnsteiner, H., & Kück, U. (2010) · Eukaryotic Cell · doi:10.1128/ec.00077-10 · Cited by 158 · see citing works
Cellular functions of cardiolipin in yeast
Joshi, A., Zhou, J., Gohil, V. M., Chen, S., & Greenberg, M. L. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2008.07.024 · Cited by 157 · see citing works
The CWI Pathway: Regulation of the Transcriptional Adaptive Response to Cell Wall Stress in Yeast
Sanz, A., García, R., Rodríguez-Peña, J., & Arroyo, J. (2017) · Journal of Fungi · doi:10.3390/jof4010001 · Cited by 149 · see citing works
Two homologous genes, DCW1 (YKL046c) and DFG5, are essential for cell growth and encode glycosylphosphatidylinositol (GPI)‐anchored membrane proteins required for cell wall biogenesis in Saccharomyces cerevisiae
Kitagaki, H., Wu, H., Shimoi, H., & Ito, K. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03244.x · Cited by 143 · see citing works
‘Strengthening the fungal cell wall through chitin-glucan cross-links: effects on morphogenesis and cell integrity’
Arroyo, J., Farkaš, V., Sanz, A. B., & Cabib, E. (2016) · Cellular Microbiology · doi:10.1111/cmi.12615 · Cited by 141 · see citing works
Antifungal Pharmacokinetics and Pharmacodynamics
Lepak, A. J., & Andes, D. R. (2015) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a019653 · Cited by 134 · see citing works
Mitotic Exit and Separation of Mother and Daughter Cells
Weiss, E. L. (2012) · Genetics · doi:10.1534/genetics.112.145516 · Cited by 131 · see citing works
The Echinocandins: Comparison of Their Pharmacokinetics, Pharmacodynamics and Clinical Applications
Wagner, C. C., Graninger, W., Presterl, E., & Joukhadar, C. (2006) · Pharmacology · doi:10.1159/000096348 · Cited by 123 · see citing works
Surface Stress Induces a Conserved Cell Wall Stress Response in the Pathogenic Fungus Candida albicans
Heilmann, C. J., Sorgo, A. G., Mohammadi, S., Sosinska, G. J., de Koster, C. G., Brul, S., de Koning, L. J., & Klis, F. M. (2013) · Eukaryotic Cell · doi:10.1128/ec.00278-12 · Cited by 122 · see citing works
Recent Studies of Protein Secretion by Filamentous Fungi.
Iwashita, K. (2002) · Journal of Bioscience and Bioengineering · doi:10.1016/s1389-1723(02)80191-8 · Cited by 121 · see citing works
Occidiofungin, a Unique Antifungal Glycopeptide Produced by a Strain of Burkholderia contaminans
Lu, S., Novák, J., Austin, F. W., Gu, G., Ellis, D., Kirk, M., Wilson-Stanford, S., Tonelli, M., & Smith, L. (2009) · Biochemistry · doi:10.1021/bi900814c · Cited by 118 · see citing works
The Candida albicans Cdr2p ATP‐binding cassette (ABC) transporter confers resistance to caspofungin
Schuetzer‐Muehlbauer, M., Willinger, B., Krapf, G., Enzinger, S., Presterl, E., & Kuchler, K. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03430.x · Cited by 111 · see citing works
Aberrant Processing of the WSC Family and Mid2p Cell Surface Sensors Results in Cell Death of Saccharomyces cerevisiae O-Mannosylation Mutants
Lommel, M., Bagnat, M., & Strahl, S. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.24.1.46-57.2004 · Cited by 111 · see citing works
European Society of Clinical Microbiology and Infectious Diseases
隋明爽, & 黄亚明 (2016) · 中华内科杂志 · doi:10.3760/cma.j.issn.0578-1426.2016.08.101 · Cited by 117 · see citing works
Scalar nanostructure of the Candida albicans cell wall; a molecular, cellular and ultrastructural analysis and interpretation
Lenardon, M. D., Sood, P., Dorfmueller, H. C., Brown, A. J. P., & Gow, N. A. R. (2020) · The Cell Surface · doi:10.1016/j.tcsw.2020.100047 · Cited by 110 · see citing works
Cell wall-associated enzymes in fungi
Rast, D. M., Baumgartner, D., Mayer, C., & Hollenstein, G. O. (2003) · Phytochemistry · doi:10.1016/s0031-9422(03)00350-9 · Cited by 110 · see citing works
The Antifungal Protein AFP from Aspergillus giganteus Inhibits Chitin Synthesis in Sensitive Fungi
Hagen, S., Marx, F., Ram, A. F. J., & Meyer, V. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.02497-06 · Cited by 102 · see citing works
Independent regulation of chitin synthase and chitinase activity in Candida albicans and Saccharomyces cerevisiae
Selvaggini, S., Munro, C. A., Paschoud, S., Sanglard, D., & Gow, N. A. R. (2004) · Microbiology · doi:10.1099/mic.0.26661-0 · Cited by 93 · see citing works
A combined chemical and enzymatic method to determine quantitatively the polysaccharide components in the cell wall of yeasts
Schiavone, M., Vax, A., Formosa‐Dague, C., Martin‐Yken, H., Dague, É., & François, J. (2014) · FEMS Yeast Research · doi:10.1111/1567-1364.12182 · Cited by 90 · see citing works
The Fungal Cell Wall: Structure, Biosynthesis, and Function
Gow, N. A. R., Latgé, J., & Munro, C. A. (2017) · ASM Press eBooks · doi:10.1128/9781555819583.ch12 · Cited by 89 · see citing works
Current Options in Antifungal Pharmacotherapy
Mohr, J., Johnson, M. D., Cooper, T., Lewis, J. S., & Ostrosky‐Zeichner, L. (2008) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.28.5.614 · Cited by 85 · see citing works
Aspergillus nidulans ChiA is a glycosylphosphatidylinositol (GPI)-anchored chitinase specifically localized at polarized growth sites
Yamazaki, H., Tanaka, A., Kaneko, J., Ohta, A., & Horiuchi, H. (2008) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2008.02.008 · Cited by 76 · see citing works
PHR1, a pH-regulated gene of Candida albicans encoding a glucan-remodelling enzyme, is required for adhesion and invasion
Calderon, J., Zavrel, M., Ragni, E., Fonzi, W. A., Rupp, S., & Popolo, L. (2010) · Microbiology · doi:10.1099/mic.0.038000-0 · Cited by 72 · see citing works
Self-citation
Bgs3p, a Putative 1,3-β-Glucan Synthase Subunit, Is Required for Cell Wall Assembly in Schizosaccharomyces pombe
Martín, V., García, B., Carnero, E., Durán, Á., & Sánchez, Y. (2003) · Eukaryotic Cell · doi:10.1128/ec.2.1.159-169.2003 · Cited by 70 · see citing works
Synthase III-dependent Chitin Is Bound to Different Acceptors Depending on Location on the Cell Wall of Budding Yeast
Cabib, E., & Durán, Á. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m414005200 · Cited by 69 · see citing works
Cell wall integrity and high osmolarity glycerol pathways are required for adaptation of Alternaria brassicicola to cell wall stress caused by brassicaceous indolic phytoalexins
Joubert, A., Bataillé‐Simoneau, N., Campion, C., Guillemette, T., Hudhomme, P., Iacomı, B., Leroy, T., Pochon, S., Poupard, P., & Simoneau, P. (2010) · Cellular Microbiology · doi:10.1111/j.1462-5822.2010.01520.x · Cited by 68 · see citing works
The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integrity
Moreno‐Ruiz, E., Ortu, G., de Groot, P. W. J., Cottier, F., Loussert-Fonta, C., Prévost, M., de Koster, C. G., Klis, F. M., Goyard, S., & d’Enfert, C. (2009) · Microbiology · doi:10.1099/mic.0.028902-0 · Cited by 62 · see citing works
Loss of Function of KRE5 Suppresses Temperature Sensitivity of Mutants Lacking Mitochondrial Anionic Lipids
Zhong, Q., Gvozdenovic‐Jeremic, J., Webster, P. C., Zhou, J., & Greenberg, M. L. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-09-0808 · Cited by 63 · see citing works
Caspofungin: Pharmacodynamics, pharmacokinetics, clinical uses and treatment outcomes
Song, J., & Stevens, D. A. (2015) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2015.1068271 · Cited by 62 · see citing works
Impact of the unfolded protein response on the pathogenicity of the necrotrophic fungus Alternaria brassicicola
Joubert, A., Simoneau, P., Campion, C., Bataillé‐Simoneau, N., Iacomı, B., Poupard, P., François, J., Georgeault, S., Sellier, E., & Guillemette, T. (2011) · Molecular Microbiology · doi:10.1111/j.1365-2958.2010.07522.x · Cited by 59 · see citing works
GAS2 and GAS4 , a Pair of Developmentally Regulated Genes Required for Spore Wall Assembly in Saccharomyces cerevisiae
Ragni, E., Coluccio, A. E., Rolli, E., Rodríguez-Peña, J. M., Colasante, G., Arroyo, J., Neiman, A. M., & Popolo, L. (2006) · Eukaryotic Cell · doi:10.1128/ec.00321-06 · Cited by 59 · see citing works
Self-citation
Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans
Shahina, Z., El-Ganiny, A. M., Minion, J., Whiteway, M. S., Sultana, T., & Dahms, T. E. S. (2018) · Fungal Biology and Biotechnology · doi:10.1186/s40694-018-0046-5 · Cited by 57 · see citing works
Scw10p, a cell-wall glucanase/transglucosidase important for cell-wall stability in Saccharomyces cerevisiae
Šesták, S. (2004) · Microbiology · doi:10.1099/mic.0.27293-0 · Cited by 54 · see citing works
Genome-wide survey of yeast mutations leading to activation of the yeast cell integrity MAPK pathway: Novel insights into diverse MAPK outcomes
Arias, P., Díez-Muñiz, S., García, R., Nombela, C., Rodríguez-Peña, J. M., & Arroyo, J. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-390 · Cited by 52 · see citing works
Sed1p and Srl1p are required to compensate for cell wall instability in Saccharomyces cerevisiae mutants defective in multiple GPI‐anchored mannoproteins
Hagen, I., Ecker, M., Lagorce, A., François, J., Šesták, S., Rachel, R., Großmann, G., Hauser, N. C., Hoheisel, J. D., Tanner, W., et al. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04064.x · Cited by 51 · see citing works
A Protein Kinase C-Encoding Gene,pkcA, Is Essential to the Viability of the Filamentous FungusAspergillus nidulans
Ichinomiya, M., Uchida, H., Koshi, Y., Ohta, A., & Horiuchi, H. (2007) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.70409 · Cited by 50 · see citing works
The cell wall sensor Wsc1p is involved in reorganization of actin cytoskeleton in response to hypo‐osmotic shock in Saccharomyces cerevisiae
Gualtieri, T., Ragni, E., Mizzi, L., Fascio, U., & Popolo, L. (2004) · Yeast · doi:10.1002/yea.1155 · Cited by 45 · see citing works
Self-citation
Disulfide Bond Structure and Domain Organization of Yeast β(1,3)-Glucanosyltransferases Involved in Cell Wall Biogenesis
Popolo, L., Ragni, E., Carotti, C., Palomares, Ó., Aardema, R., Back, J. W., Dekker, H. L., de Koning, L. J., de Jong, L., & de Koster, C. G. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801562200 · Cited by 42 · see citing works
Self-citation
Effect of yeast strain and fermentation conditions on the release of cell wall polysaccharides
Giovani, G., Canuti, V., & Rosi, I. (2009) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2009.12.009 · Cited by 40 · see citing works
Schizosaccharomyces pombe Pmr1p Is Essential for Cell Wall Integrity and Is Required for Polarized Cell Growth and Cytokinesis
Cortés, J. C. G., Katoh-Fukui, R., Moto, K., Ribas, J. C., & Ishiguro, J. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.5.1124-1135.2004 · Cited by 39 · see citing works
Characterization of Sensor-Specific Stress Response by Transcriptional Profiling of wsc1 and mid2 Deletion Strains and Chimeric Sensors in Saccharomyces cerevisiae
Bermejo, C., García, R., Straede, A., Rodríguez-Peña, J. M., Nombela, C., Heinisch, J. J., & Arroyo, J. (2010) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2010.0060 · Cited by 38 · see citing works
Genomics in the detection of damage in microbial systems: cell wall stress in yeast
Arroyo, J., Bermejo, C., García, R., & Rodríguez-Peña, J. M. (2009) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2008.02676.x · Cited by 36 · see citing works
The Fungal Cell Wall
Latgé, J., & Calderone, R. (2006) · Springer eBooks · doi:10.1007/3-540-28135-5_5 · Cited by 33 · see citing works
Priming and elongation of chitin chains: Implications for chitin synthase mechanism
Orlean, P., & Funai, D. (2018) · The Cell Surface · doi:10.1016/j.tcsw.2018.100017 · Cited by 33 · see citing works
Loss of Cardiolipin Leads to Longevity Defects That Are Alleviated by Alterations in Stress Response Signaling
Zhou, J., Zhong, Q., Li, G., & Greenberg, M. L. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.003236 · Cited by 31 · see citing works
The Mkk2 MAPKK Regulates Cell Wall Biogenesis in Cooperation with the Cek1-Pathway in Candida albicans
Román, E., Alonso‐Monge, R., Miranda, A., & Plá, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0133476 · Cited by 31 · see citing works
The ‘yeast cell wall chip’ – a tool to analyse the regulation of cell wall biogenesis in Saccharomyces cerevisiae
Rodríguez-Peña, J. M., Pérez‐Díaz, R. M., Alvarez, S., Bermejo, C., García, R., Santiago, C., Nombela, C., & Arroyo, J. (2005) · Microbiology · doi:10.1099/mic.0.27989-0 · Cited by 31 · see citing works
Catalytic properties of the Gas family β-(1,3)-glucanosyltransferases active in fungal cell-wall biogenesis as determined by a novel fluorescent assay
Mazáň, M., Ragni, E., Popolo, L., & Farkaš, V. (2011) · Biochemical Journal · doi:10.1042/bj20110405 · Cited by 30 · see citing works
Self-citation
The eagle-like effect of echinocandins: what’s in a name?
Vanstraelen, K., Lagrou, K., Maertens, J., Wauters, J., Willems, L., & Spriet, I. (2013) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2013.841543 · Cited by 28 · see citing works
PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes
Eckert, S. E., Heinz, W. J., Zakikhany, K., Thewes, S., Haynes, K., Hube, B., & Mühlschlegel, F. A. (2007) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2006.12.006 · Cited by 29 · see citing works
Comparison of different zinc precursors for the construction of zeolitic imidazolate framework-8 artificial shells on living cells
Chen, W., Kong, S. Q., Lu, M., Chen, F., Cai, W., Du, L., Wang, J., & Wu, C. (2019) · Soft Matter · doi:10.1039/c9sm01907c · Cited by 28 · see citing works
L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB1 synthesis by disrupting cell structure and antioxidant system balance
Qiu, M., Qiu, L., Deng, Q., Fang, Z., Sun, L., Wang, Y., Gooneratne, R., & Zhao, J. J. (2023) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2023.132218 · Cited by 28 · see citing works
A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus neoformans
Probst, C., Hallas-Møller, M., Ipsen, J. Ø., Brooks, J. T., Andersen, K., Haon, M., Berrin, J., Martens, H. J., Nichols, C. B., Johansen, K. S., et al. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1010946 · Cited by 26 · see citing works
A yeast strain biosensor to detect cell wall-perturbing agents
Rodríguez-Peña, J. M., Díez-Muñiz, S., Nombela, C., & Arroyo, J. (2007) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2007.10.006 · Cited by 26 · see citing works
Dissection of the Candida albicans class I chitin synthase promoters
Lenardon, M. D., Lesiak, I., Munro, C. A., & Gow, N. A. R. (2009) · Molecular Genetics and Genomics · doi:10.1007/s00438-009-0423-0 · Cited by 26 · see citing works
The cell wall of Paracoccidioides brasiliensis: insights from its transcriptome.
Tomazett, P. K., Cruz, A. H. D. S., Bonfim, S. M. R. C., Soares, C. M. D. A., & Pereira, M. (2005) · PubMed · Cited by 26 · see citing works
Cell compensatory responses of fungi to damage of the cell wall induced by Calcofluor White and Congo Red with emphasis on Sporothrix schenckii and Sporothrix globosa. A review
Ortiz-Ramírez, J. A., Cuéllar‐Cruz, M., & López-Romero, E. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.976924 · Cited by 25 · see citing works
Glycosylphosphatidylinositol Anchor Biosynthesis Pathway-Related Protein GPI7 Is Required for the Vegetative Growth and Pathogenicity of Colletotrichum graminicola
Mei, J., Ning, N., Wu, H., Chen, X., Li, Z., & Liu, W. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23062985 · Cited by 24 · see citing works
Impaired PRPP-synthesizing capacity compromises cell integrity signalling in Saccharomyces cerevisiae
Wang, K. (2004) · Microbiology · doi:10.1099/mic.0.27373-0 · Cited by 22 · see citing works
Expression of asexual developmental regulator gene abaA is affected in the double mutants of classes I and II chitin synthase genes, chsC and chsA, of Aspergillus nidulans
Ichinomiya, M., Ohta, A., & Horiuchi, H. (2005) · Current Genetics · doi:10.1007/s00294-005-0004-7 · Cited by 22 · see citing works
Change of cell wall chitin content in amphotericin B resistant Kluyveromyces strains
Bahmed, K., Bonaly, R., Wathier, M., Pucci, B., & Coulon, J. (2002) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(02)01000-5 · Cited by 21 · see citing works
Influence of N-Glycosylation on Saccharomyces cerevisiae Morphology: A Golgi Glycosylation Mutant Shows Cell Division Defects
Zhou, J., Zhang, H., Liu, X., Wang, P. G., & Qi, Q. (2007) · Current Microbiology · doi:10.1007/s00284-006-0585-5 · Cited by 20 · see citing works
Response of Paracoccidioides brasiliensis Pb01 to stressor agents and cell wall osmoregulators
Tomazett, P. K., Castro, N. D. S., Lenzi, H. L., Soares, C. M. D. A., & Pereira, M. (2010) · Fungal Biology · doi:10.1016/j.funbio.2010.10.005 · Cited by 21 · see citing works
Poacic acid, a β‐1,3‐glucan–binding antifungal agent, inhibits cell‐wall remodeling and activates transcriptional responses regulated by the cell‐wall integrity and high‐osmolarity glycerol pathways in yeast
García, R., Itto‐Nakama, K., Rodríguez-Peña, J. M., Chen, X., Sanz, A. B., de Lorenzo, A., Pavón‐Vergés, M., Kubo, K., Ohnuki, S., Nombela, C., et al. (2021) · The FASEB Journal · doi:10.1096/fj.202100278r · Cited by 19 · see citing works
Self-citation
A newly-isolated Cd-loving Purpureocillium sp. strain YZ1 substantially alleviates Cd toxicity to wheat
Zheng, X., Yang, S., Chen, L., Kimotho, R. N., Chen, M., Chen, J., Zhang, J., & Li, X. (2021) · Plant and Soil · doi:10.1007/s11104-021-04954-5 · Cited by 18 · see citing works
Flavoenzyme CrmK-mediated substrate recycling in caerulomycin biosynthesis
Zhu, Y., Picard, M.-È., Zhang, Q., Barma, J., Després, X. M., Mei, X., Zhang, L., Duvignaud, J., Couture, M., Zhu, W., et al. (2016) · Chemical Science · doi:10.1039/c6sc00771f · Cited by 18 · see citing works
Differential cell wall remodeling of two chitin synthase deletants Δchs3A and Δchs3B in the pathogenic yeast Candida glabrata: Cell wall remodeling of Δchs3 mutants
Ueno, K., Namiki, Y., Mitani, H., Yamaguchi, M., & Chibana, H. (2011) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2011.00728.x · Cited by 17 · see citing works
Hyperactive TORC 1 sensitizes yeast cells to endoplasmic reticulum stress by compromising cell wall integrity
Ahmed, K., Carter, D. E., & Lajoie, P. (2019) · FEBS Letters · doi:10.1002/1873-3468.13463 · Cited by 17 · see citing works
Secondary cell wall formation in Cryptococcus neoformans as a rescue mechanism against acid-induced autolysis
FarkaÅ¡, V., Takeo, K., Maceková, D., Ohkusu, M., Yoshida, S., & Sipiczki, M. (2009) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2008.00478.x · Cited by 17 · see citing works
Spiked Nanostructures Disrupt Fungal Biofilm and Impart Increased Sensitivity to Antifungal Treatment
Hayles, A., Bright, R., Wood, J., Palms, D., Zilm, P. S., Brown, T. D., Barker, D., & Vasilev, K. A. (2022) · Advanced Materials Interfaces · doi:10.1002/admi.202102353 · Cited by 14 · see citing works
Yeast RNA exosome activity is necessary for maintaining cell wall stability through proper protein glycosylation
Novačić, A., Beauvais, V., Oskomić, M., Štrbac, L., Dantec, A. L., Rahmouni, A. R., & Stuparević, I. (2021) · Molecular Biology of the Cell · doi:10.1091/mbc.e20-08-0544-t · Cited by 14 · see citing works
Sdd3 regulates the biofilm formation of Candida albicans via the Rho1-PKC-MAPK pathway
Pang, L. M., Zeng, G., Chow, E. W. L., Xu, X., Li, N., Kok, Y. J., Chong, S. C., Bi, X., Gao, J., Seneviratne, C. J., et al. (2024) · mBio · doi:10.1128/mbio.03283-24 · Cited by 13 · see citing works
Yeast Stress Response to Synthetic Constructs
Tartik, M. (2026) · ACS Synthetic Biology · doi:10.1021/acssynbio.5c00715 · Cited by 13 · see citing works
KlHsl1 is a component of glycerol response pathways in the milk yeast Kluyveromyces lactis
Cialfi, S., Uccelletti, D., Carducci, A., Wésolowski‐Louvel, M., Mancini, P., Heipieper, H. J., & Saliola, M. (2011) · Microbiology · doi:10.1099/mic.0.044040-0 · Cited by 12 · see citing works
Overview and perspectives on the transcriptome of Paracoccidioides brasiliensis
de Andrade, R. V., da Silva, S. P., Torres, F. A. G., Poças-Fonseca, M. J., Silva-Pereira, I., Maranhão, A. Q., Campos, E. G., de Moraes, L. M. P., Jesuíno, R. S. A., Pereira, M., et al. (2005) · Revista Iberoamericana de Micología · doi:10.1016/s1130-1406(05)70044-9 · Cited by 12 · see citing works
Responses of Sporothrix globosa to the cell wall perturbing agents Congo Red and Calcofluor White
Ortiz-Ramírez, J. A., Cuéllar‐Cruz, M., & López-Romero, E. (2021) · Antonie van Leeuwenhoek · doi:10.1007/s10482-021-01545-3 · Cited by 11 · see citing works
Transcription levels of CHS5 and CHS4 genes in Paracoccidioides brasiliensis mycelial phase, respond to alterations in external osmolarity, oxidative stress and glucose concentration
Niño‐Vega, G. A., Sorais, F., & San-Blas, G. (2009) · Mycological Research · doi:10.1016/j.mycres.2009.07.005 · Cited by 11 · see citing works
Biosynthesis of amorphous mesoporous aluminophosphates using yeast cells as templates
Sifontes, Á. B., González, G., Tovar, L. M., Méndez, F. J., Gomes, M. E., Cañizales, E., Niño‐Vega, G. A., Villalobos-Duno, H., & Brito, J. L. (2012) · Materials Research Bulletin · doi:10.1016/j.materresbull.2012.11.016 · Cited by 11 · see citing works
Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling
Degani, G., Ragni, E., Botias, P., Ravasio, D., Calderon, J., Pianezzola, E., Rodriguez-Peña, J. M., Vanoni, M. A., Arroyo, J., Fonzi, W. A., et al. (2016) · BMC Genomics · doi:10.1186/s12864-016-2853-5 · Cited by 10 · see citing works
Self-citation

Cell wall dynamics in yeast
Smits, G. J., Kapteyn, J. C., ENDE, H. V. D., & Klis, F. M. (1999) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(99)80061-7 · Cited by 227 · see citing works
Hilfe für gestresste Hefen: der Zellwand-Integritätsweg
Schweisthal, S., Sterk, C. C., & Heinisch, J. J. (2016) · BIOspektrum · doi:10.1007/s12268-016-0664-5
Fission yeast cell wall biosynthesis and cell integrity signalling
Pérez, P., Cortés, J. C. G., Cansado, J., & Ribas, J. C. (2018) · The Cell Surface · doi:10.1016/j.tcsw.2018.10.001 · Cited by 62 · see citing works
Dynamics of cell wall structure in Saccharomyces cerevisiae
Klis, F. M., Mol, P. C., Hellingwerf, K. J., & Brul, S. (2002) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2002.tb00613.x · Cited by 1,007 · see citing works
Cell wall maintenance in fungi
de Nobel, H., ENDE, H. V. D., & Klis, F. M. (2000) · Trends in Microbiology · doi:10.1016/s0966-842x(00)01805-9 · Cited by 83 · see citing works

Authors: Popolo, L., Gualtieri, T., & Ragni, E.
Affiliations: University of Milan (IT)
Corresponding author: Popolo, L.
ORCID: Popolo, L.
Ragni, E.
Venue: Medical Mycology
Publisher: Oxford University Press (OUP)
Published: 2001-01
Volume: 39
Issue: 1
Pages: 111-121
ISSN: 0268-1218 (ISSN-L)
1369-3786
1460-2709
DOI: 10.1080/mmy.39.1.111.121
OpenAlex: W2162102216
Cited by: 142
References: 51
Citations by year: 2026: 3 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 5 · 2021: 6 · 2020: 7 · 2019: 5 · 2018: 4 · 2017: 3 · 2016: 4 · 2015: 3 · 2014: 6 · 2013: 2 · 2012: 7
FWCI: 2.89
Type: journal article
Language: en
Open access: closed
Locations: Medical Mycology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
Keywords: yeast cell wall, salvage pathway, cell wall damage, cell wall remodeling, extracellular matrix, FKS1, GAS1, mating factor, antifungal drug targets, fungal pathogens, Saccharomyces cerevisiae
MeSH terms: Cell Wall, Fungal Proteins, Fungi, Protein Kinase C, Signal Transduction, Calcineurin, MAP Kinase Signaling System

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The yeast cell-wall salvage pathway

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks