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Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system.

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Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines

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[4] Thrombospondins

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Disulfides modulate RGD-inhibitable cell adhesive activity of thrombospondin.

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Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

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A novel protein interacts with the major transforming growth factor-beta responsive element in the plasminogen activator inhibitor type-1 gene.

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CYR61 (CCN1) Is Essential for Placental Development and Vascular Integrity

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CD36, a Class B Scavenger Receptor, Is Expressed on Microglia in Alzheimer's Disease Brains and Can Mediate Production of Reactive Oxygen Species in Response to β-Amyloid Fibrils

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The Angiogenic Factor Cyr61 Activates a Genetic Program for Wound Healing in Human Skin Fibroblasts

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Adipokines: New potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

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Pro-angiogenic Activities of CYR61 (CCN1) Mediated through Integrins αvβ3 and α6β1 in Human Umbilical Vein Endothelial Cells

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Extracellular Matrix Cues Regulate Mechanosensing and Mechanotransduction of Cancer Cells

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Identification of a novel integrin α6β1 binding site in the angiogenic Inducer CCN1 (CYR61)

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The Matricellular Protein CCN1 Is Essential for Cardiac Development

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The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling

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Thrombospondin 1 and Its Diverse Roles as a Regulator of Extracellular Matrix in Fibrotic Disease

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Hypoxia-inducible miR-210 contributes to preeclampsia via targeting thrombospondin type I domain containing 7A

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The matricellular protein periostin contributes to proper collagen function and is downregulated during skin aging

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β1 Integrin- and Proteoglycan-Mediated Stimulation of T Lymphoma Cell Adhesion and Mitogen-Activated Protein Kinase Signaling by Thrombospondin-1 and Thrombospondin-1 Peptides

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Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines

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Enhanced proangiogenic signaling in thrombospondin-1-deficient retinal endothelial cells

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The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47

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Thrombospondin module 1 domain (TSP1) of the matricellular protein CCN3 shows an atypical disulfide pattern and incomplete CWR layersPreprint

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Purification and Analysis of Thrombospondin‐1

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Abstract 17049: Upregulation of the Matricellular Protein Thrombospondin (TSP)-1 in the db/db Heart Regulates Matrix Remodeling and Induces Vascular Rarefaction

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