Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

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Items 401–500 of 832

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2. NLRP3 inflammasome inhibitor glyburide expedites diabetic-induced impaired fracture healing
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13. Ultraviolet Radiation‐Induced Downregulation of SERCA2 Mediates Activation of NLRP3 Inflammasome in Basal Cell Carcinoma
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15. IAPP/amylin deposition, which is correlated with expressions of ASC and IL-1β in β-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation
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16. Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages
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18. Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia
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19. Role of Innate Immunity in Diabetes and Metabolism: Recent Progress in the Study of Inflammasomes
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24. Sintered Indium-Tin Oxide Particles Induce Pro-Inflammatory Responses In Vitro, in Part through Inflammasome Activation
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25. Second-Generation Antidiabetic Sulfonylureas Inhibit Candida albicans and Candidalysin-Mediated Activation of the NLRP3 Inflammasome
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26. NLRP3 Inflammasome Biomarker—Could Be the New Tool for Improved Cardiometabolic Syndrome Outcome
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27. Development of novel oridonin analogs as specifically targeted NLRP3 inflammasome inhibitors for the treatment of dextran sulfate sodium-induced colitis
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28. Regulation and functions of the NLRP3 inflammasome in RNA virus infection
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29. Inhibition of the nucleotide-binding domain, leucine-rich containing family, pyrin-domain containing 3 inflammasome reduces the severity of experimentally induced acute pancreatitis in obese mice
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30. Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae
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31. Obovatol inhibits NLRP3, AIM2, and non-canonical inflammasome activation
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32. Giardia spp. promote the production of antimicrobial peptides and attenuate disease severity induced by attaching and effacing enteropathogens via the induction of the NLRP3 inflammasome
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33. NLRP3 Inflammasome-Mediated Pyroptosis Pathway Contributes to the Pathogenesis of Candida albicans Keratitis
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34. Cigarette smoke induces the pyroptosis of urothelial cells through ROS/NLRP3/caspase‐1 signaling pathway
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35. Glibenclamide attenuates myocardial injury by lipopolysaccharides in streptozotocin-induced diabetic mice
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36. Role of inflammasome regulation on immune modulators
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37. The Role of NLRP3 Inflammasome in Radiation-Induced Cardiovascular Injury
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38. Inflammatory Mechanisms in Parkinson’s Disease: From Pathogenesis to Targeted Therapies
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39. FANCC deficiency mediates microglial pyroptosis and secondary neuronal apoptosis in spinal cord contusion
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40. Inflammasomes as mediators of inflammation in HIV-1 infection
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41. The Antidiabetic Agent Glibenclamide Protects Airway Hyperresponsiveness and Inflammation in Mice
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42. NLRP3 has a sweet tooth
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43. FANCA and FANCC modulate TLR and p38 MAPK–dependent expression of IL-1β in macrophages
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44. The Endoribonuclease Activity Essential for the Nonstructural Protein 11 of Porcine Reproductive and Respiratory Syndrome Virus to Inhibit NLRP3 Inflammasome-Mediated IL-1β Induction
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45. Ugonin U stimulates NLRP3 inflammasome activation and enhances inflammasome-mediated pathogen clearance
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46. Pyroptosis in bone loss
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47. NLRP3 Inflammasome Inhibitors for Antiepileptogenic Drug Discovery and Development
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48. The inflammasome regulatory pathway and infections: Role in pathophysiology and clinical implications
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49. New views and possibilities of antidiabetic drugs in treating and/or preventing mild cognitive impairment and Alzheimer’s Disease
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50. Pristimerin protects against inflammation and metabolic disorder in mice through inhibition of NLRP3 inflammasome activation
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51. Inflammatory Basis of Atherosclerosis: Modulation by Sex Hormones
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52. Chalcone: A potential scaffold for NLRP3 inflammasome inhibitors
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53. Interrogating direct NLRP3 engagement and functional inflammasome inhibition using cellular assays
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54. Glyburide and retinoic acid synergize to promote wound healing by anti-inflammation and RIP140 degradation
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55. The Emerging Role of Inflammasomes as Central Mediators in Inflammatory Bladder Pathology
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56. Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies
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57. Metformin promotes Mycobacterium tuberculosis killing and increases the production of human β-defensins in lung epithelial cells and macrophages
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58. Targeting the NOD-Like Receptor Pyrin Domain Containing 3 Inflammasome to Improve Healing of Diabetic Wounds
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59. Niclosamide activates the NLRP3 inflammasome by intracellular acidification and mitochondrial inhibition
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60. The NLRP3 Inflammasome as a Pharmacological Target
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61. Novel Small-Molecule Inhibitor of NLRP3 Inflammasome Reverses Cognitive Impairment in an Alzheimer’s Disease Model
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71. Deciphering the ATP-binding mechanism(s) in NLRP-NACHT 3D models using structural bioinformatics approaches
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72. Spirodalesol, an NLRP3 Inflammasome Activation Inhibitor
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73. NLRs as Helpline in the Brain: Mechanisms and Therapeutic Implications
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74. Activation of the NLRP3 and AIM2 inflammasomes in a mouse model ofSchistosoma mansoniinfection
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86. Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
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98. A new lead to NLRP3 inhibition
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100. Hierarchical Regulation of Wound Healing by NOD-Like Receptors in Cardiovascular Disease
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