Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

Gout-associated uric acid crystals activate the NALP3 inflammasome

Martinon, F., Pétrilli, V., Mayor, A., Tardivel, A., & Tschopp, J. (2006) · Nature · doi:10.1038/nature04516 · Cited by 5,326

Cryopyrin activates the inflammasome in response to toxins and ATP

Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P., Weinrauch, Y., Monack, D. M., & Dixit, V. M. (2006) · Nature · doi:10.1038/nature04515 · Cited by 3,080

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Hornung, V., Bauernfeind, F., Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A., & Latz, E. (2008) · Nature Immunology · doi:10.1038/ni.1631 · Cited by 3,065

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

Dostert, C., Pétrilli, V., Van Bruggen, R., Steele, C., Mossman, B. T., & Tschopp, J. (2008) · Science · doi:10.1126/science.1156995 · Cited by 2,658

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Halle, A., Hornung, V., Petzold, G. C., Stewart, C. R., Monks, B. G., Reinheckel, T., Fitzgerald, K. A., Latz, E., Moore, K. J., & Golenbock, D. T. (2008) · Nature Immunology · doi:10.1038/ni.1636 · Cited by 2,441

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Mariathasan, S., Newton, K., Monack, D. M., Vucic, D., French, D. M., Lee, W. P., Roose-Girma, M., Erickson, S. L., & Dixit, V. M. (2004) · Nature · doi:10.1038/nature02664 · Cited by 1,864

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome

Hoffman, H. M., Mueller, J. L., Broide, D. H., Wanderer, A. A., & Kolodner, R. D. (2001) · Nature Genetics · doi:10.1038/ng756 · Cited by 1,679

Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor

Pelegrı́n, P., & Surprenant, A. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601378 · Cited by 1,490

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

Aguilar-Bryan, L., Nichols, C. G., Wechsler, S. W., Clement, J. P., Boyd, A. E., González, G., Herrera-Sosa, H., Nguy, K., Bryan, J., & Nelson, D. A. (1995) · Science · doi:10.1126/science.7716547 · Cited by 1,315

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Kanneganti, T., Özören, N., Body–Malapel, M., Amer, A. O., Park, J., Franchi, L., Whitfield, J. R., Barchet, W., Colonna, M., Vandenabeele, P., et al. (2006) · Nature · doi:10.1038/nature04517 · Cited by 1,149

Anti-inflammatory Effects of Probiotics and Their Metabolites: Possible Role for Epigenetic Effects

Türker, N., Toh, Z. Q., Karagiannis, T. C., & Licciardi, P. V. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0706-9_5 · Cited by 4

Changes in gut toll-like receptor-4 and nod-like receptor family pyrin domain containing-3 innate pathways in liver cirrhosis rats with bacterial translocation

Liu, L., Zhang, C., Hu, Y., Zhou, L., & Tan, Q. (2016) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2016.02.008 · Cited by 3

Drugs Targeting NLRP3 Inflammasome in the Treatment of Diabetic Bone Disorders

Chen, Y., Aili, M., Chen, F., Gong, Y., Chen, X., & Zhang, L. (2023) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530323666230320164235 · Cited by 3

Mycobacterium tuberculosis Central Metabolism Is Key Regulator of Macrophage Pyroptosis and Host Immunity

Maxson, M. E., Das, L., Goldberg, M. F., Porcelli, S. A., Chan, J., & Jacobs, W. R. (2023) · Pathogens · doi:10.3390/pathogens12091109 · Cited by 3

Exploring Inflammasome Complex as a Therapeutic Approach in Inflammatory Diseases

Sultana, S., Viet, T. D., Oishy, T. A., Kazi, E., Micolucci, L., Mollah, A. K. M. M., Akhtar, M. M., & Islam, M. S. (2023) · Future Pharmacology · doi:10.3390/futurepharmacol3040048 · Cited by 3

Inflammasome Activation by Pathogenic Crystals and Particles

Re, F. (2011) · Springer eBooks · doi:10.1007/978-3-0348-0148-5_6 · Cited by 3

Sphingosine-1-phosphate transport and its role in immunology

Reitsema, V. A., Bouma, H. R., & Kok, J. W. (2014) · AIMS molecular science · doi:10.3934/molsci.2014.4.183 · Cited by 4

NLRP3 inflammasome: A novel target for T2DM treatment?

Jiang, H., & Zhou, R. (2016) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/n972016-00653 · Cited by 3

The Inflammation Superhighway

Ibrahim, J. W., Garantziotis, S., & Savani, R. C. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-68353-1.00009-9 · Cited by 3

A novel cysteine protease inhibitor in Baylisascaris schroederi migratory larvae regulates inflammasome activation through the TLR4–ROS–NLRP3 pathway

Xu, J., Gu, X., Xie, Y., He, R., Xu, J., Xiong, L., Peng, X., & Yang, G. (2022) · Parasites & Vectors · doi:10.1186/s13071-022-05466-6 · Cited by 3

Interview: a conversation with Vishva M Dixit on his journey from remote African village to apoptosis, necroptosis and the inflammasome

Dixit, V. M. (2019) · Cell Death and Differentiation · doi:10.1038/s41418-019-0294-9 · Cited by 3

Vaginal microbes alter epithelial transcriptomic and epigenomic modifications providing insight into the molecular mechanisms for susceptibility to adverse reproductive outcomesPreprint

Elovitz, M. A., Anton, L., Cristancho, A. G., Ferguson, B., Joseph, A., & Ravel, J. (2023) · Research Square · doi:10.21203/rs.3.rs-3580132/v1 · Cited by 3

Glibenclamide Prevents Inflammation by Targeting NLRP3 Inflammasome Activation in vitro

Хилажева, Е. Д., Panina, Y. A., Mosiagina, A. I., Belozor, О. S., & Komleva, Y. K. (2024) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s002209302403013x · Cited by 2

Glibenclamide-encapsulated Liposomes alleviate LPS-induced Inflammatory Cascade through NLRP3 inhibition in macrophages

Kanika, Prakash, R., Kumar, A., Mahajan, S., Ali, N., Raza, S. S., & Khan, R. (2024) · Biomedical Materials · doi:10.1088/1748-605x/ad8851 · Cited by 2

A complex of NLRP3 with caspase-4 is essential for inflammasome activation by Tannerella forsythia infection

Hsu, C.-W., Okano, T., Niinuma, Y., Leewananthawet, A., Iida, T., Onsoi, P., Boonyaleka, K., Ashida, H., & Suzuki, T. (2024) · International Immunology · doi:10.1093/intimm/dxae071 · Cited by 2

Glyburide Accelerates the Process of Tendon Healing by Inhibiting NLRP3 Inflammasome in Calcific Tendinopathy

Chen, W., Qi, W., Jia, M., Yao, Q., Yang, Y., Su, Y., & Xiang, X. (2025) · The American Journal of Sports Medicine · doi:10.1177/03635465251356463 · Cited by 2

Beyond the innate immune system: rethinking inflammasomes in multiple sclerosis

Duran, G., Verreycken, J., Dombrowski, Y., Lamkanfi, M., Baeten, P., & Broux, B. (2025) · Trends in Immunology · doi:10.1016/j.it.2025.10.014 · Cited by 2

Emerging strategies in drug repurposing for decreasing the risk of age-related macular degeneration

Zhou, B., Mokhashi, N., & Skondra, D. (2026) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2026.2635492 · Cited by 2

The roles of NLRP3 inflammasome in diabetic cardiomyopathy and potential targeted therapeutics

Zhang, M., & Liu, Y. (2026) · Genes & Diseases · doi:10.1016/j.gendis.2026.102140 · Cited by 2

Targeting the NLRP3 inflammasome in Alzheimer’s disease: Mechanistic insights and therapeutic advances

廉文文, Zhou, F., Tong, Z., 夏聪媛, Yu, Y., He, J., Jiekun, X., & Zhang, W. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103273 · Cited by 2

Immune Sensors and Effectors of Health and Disease

Mamik, M. K., & Power, C. (2016) · Springer eBooks · doi:10.1007/978-3-319-44022-4_8 · Cited by 2

Mechanisms of innate immunity in pathogenesis of psoriasis: approaches to targeted therapy

Merkushova, E. D., Хасанова, Е. М., & Gankovskaya, L. V. (2020) · Medical Immunology (Russia) · doi:10.15789/1563-0625-moi-1949 · Cited by 2

Antiinflammation Derived Suzuki-Coupled Fenbufens as COX-2 Inhibitors: Minilibrary Construction and Bioassay

Farn, S., Lai, Y.-B., Hua, K.-F., Chen, H.-P., Yu, T., Lo, S.-N., Shen, L.-H., Sheu, R.-J., & Yu, C. (2022) · Molecules · doi:10.3390/molecules27092850 · Cited by 2

The NLRP3 Inflammasome as a Target for Antiinflammatory Drugs

Rowaiye, A. B., Oni, S. O., Abubakar, U. S., Aondona, P. Y., Emenyeonu, L. C., & Agbalalah, T. (2024) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815223941124010009 · Cited by 2

Effect of experimental gestational diabetes and administration of glibenclamide on mRNA level of NLRP3-inflammasome and distribution of NLRP3+-cells in mesenteric lymph nodes in progeny

Prozorova, Т. М., Kamyshna, V., & Kamyshnyi, O. (2017) · Pathologia · doi:10.14739/2310-1237.2017.2.109269 · Cited by 2

Therapeutic opportunities targeting the NLRP3 inflammasome

Hooftman, A., Zotta, A., & O'Neill, L. A. J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00035-9 · Cited by 1

Characterization of Inflammasomes and Their Regulation in the Red Fox

Ahn, H., Jeong, D., Lee, G., Lee, S., Yang, J.-J., Kim, Y., Hahn, T., Choi, S., & Lee, G. (2023) · Animals · doi:10.3390/ani13243842 · Cited by 1

Phytochemicals as promising therapeutic approaches for inflammasomes-related metabolic disorders

Khuspe, P. R., Pagar, R. R., Pardeshi, S. R., Meshram, P. D., Gholap, A. D., Dhole, S. J., Kole, E. B., & Naik, J. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-31698-2.00022-9 · Cited by 1

Targeting the NLRP3 Inflammasome: Novel Inhibitors for Cardiovascular Diseases Management — A Narrative Review

Momen, Y. S. (2026) · Drug Development Research · doi:10.1002/ddr.70283 · Cited by 2

Targeting inflammasome, IL-1β, and coagulation in melioidosis

Melo, G., & Re, F. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1816008 · Cited by 1

Role of NLRP3 Inflammasome Inhibitors in Endothelial Dysfunction and Vascular Repair

Samyuktha, T., Sridharan, Y., Ganesan, K., & Ramkumar, K. M. (2026) · Antioxidants · doi:10.3390/antiox15070784 · Cited by 1

Modulation of inflammasome biology in age-associated neurodegenerative diseases: Therapeutic potential of endogenous gasotransmitters and synthetic molecules

Waseem, A., Ghosh, S., Kumari, M., Raza, S. S., & Verma, S. K. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103257 · Cited by 1

Inflammation as a therapeutic target to improve kidney and cardiovascular outcomes

Tuttle, K. R., Kanbay, M., Alicic, R. Z., Carrero, J. J., Çöpür, S., Navar, A. M., Neuen, B. L., Perkovic, V., Rossing, P. R., Marx, N., et al. (2026) · Nature Reviews Nephrology · doi:10.1038/s41581-026-01117-6 · Cited by 2

Role of macrophage ATP metabolism disorder in SiO2‑induced pulmonary fibrosis: a review

Hu, H., Fu, Y., Du, S., Zhang, Y., Zhang, Z., & Han, G. (2025) · Purinergic Signalling · doi:10.1007/s11302-025-10093-8 · Cited by 2

Disparate Activation of the Inflammasome by Chitin and Chitosan: A Dissertation

Bueter, C. L. (2013) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/m2w02z · Cited by 1

Adaptive and Innate Immune Systems

Kataoka, T. (2017) · Springer eBooks · doi:10.1007/978-4-431-56529-1_5 · Cited by 1

Molecular mechanism of pyroptosis and its role in cancer

Wu, S., Wong, P., Chen, Y., Su, L., & Qiu, X. (2020) · Scientia Sinica Vitae · doi:10.1360/ssv-2020-0065 · Cited by 1

Inflammasomes as integral components of PANoptosomes in the regulation of cell death

Tweedell, R. E., Christgen, S. L., & Kanneganti, T. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00033-5 · Cited by 1

ASSOCIATION BETWEEN TYPE 2 DIABETES MELLITUS AND COVID-19 SEVERITY: A LITERATURE REVIEW

Gowthavaram, C. A. (2023) · Asian Journal of Pharmaceutical and Clinical Research · doi:10.22159/ajpcr.2023.v16i5.47961 · Cited by 1

Mechanism of linezolid-induced NLRP3 inflammasome activation

He, Q. (2012) · doi:10.17077/etd.s5eoktcw · Cited by 1

Role of NLRP3 in colitis and colitis associated colorectal cancer

Perera, A. P. (2019) · UTAS Research Repository · doi:10.25959/100.00034330 · Cited by 1

Hidrogenación catalítica de aceites vegetales

Gutiérrez-Ortiz, J. I., González, C. A. L., & González-Velasco, J. R. (1997) · Alimentación, equipos y tecnología · Cited by 1

Pyroptosis

Lawlor, K. E., Conos, S. A., & Vince, J. E. (2018) · Wiley eBooks · doi:10.1002/9781119432463.ch15 · Cited by 1

Vaginal microbes alter epithelial transcriptome and induce epigenomic modifications providing insight into mechanisms for susceptibility to adverse reproductive outcomesPreprint

Elovitz, M. A., Anton, L., Cristancho, A. G., Ferguson, B., Joseph, A., & Ravel, J. (2024) · Research Square · doi:10.21203/rs.3.rs-4385224/v1 · Cited by 1

Role of Inflammasomes in Obesity

Dixit, V. D. (2013) · Else Kröner-Fresenius Symposia · doi:10.1159/000346505

Vitamin D induces the release of IL-1b via activation of the NLRP3 inflammasome

Tulk, S. E. (2012) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/28659

Role of the inflammasome pathway in atherosclerosis

Rajamäki, K. (2015) · Työväentutkimus Vuosikirja

Extracellular adenosine as a novel neuroimmune modulator

Chiu, G. S. (2014) · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)

Mechanisms of Innate Immunity in Polymicrobial Sepsis

Jin, L. (2014) · Louisiana State University · doi:10.31390/gradschool_dissertations.2935

Syndromes and Diseases

Abramovits, W., & Oquendo, M. (2013)

Defining stress-induced systemic sterile inflammatory responses: Network, signals, and pathways

Maslanik, T. (2012) · CU Scholar (University of Colorado Boulder)

Advances in regulation mechanism of inflammasomes

Da, W. (2015) · Progress in Microbiology and Immunology

NLRP3 and Its Role in Autoinflammatory Disorders

Ören, S., Ozafsar, O., & Demirkaya, E. (2016) · Annals of Paediatric Rheumatology · doi:10.5455/apr.062920160541

QUANTITATIVE ANALYSIS OF 5-CHLORO-2-METHOXY-N-[2-(4-SULFAMOYLPHENYL)ETHYL]BENZAMIDE (GLYBURIDE ANALOGUE, GA) IN MOUSE PLASMA AND WHOLE BLOOD USING A MICRO-EXTRACTION AND LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY

Zalavadia, A. A. (2016) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/s5w8-0p17

Interplay Between Autophagy and Inflammasomes

Liang, Q., Ge, J., & Jin, X. (2016) · Springer eBooks · doi:10.1007/978-3-319-30079-5_4

Functional characterisation of a novel immune modulatory molecule from Fasciola hepatica

Alvarado, R. (2014) · OPUS - Open Publications of UTS Scholars (University of Technology Sydney)

Trypanosoma cruzi Host Resistance to Response and β Inflammasomes Mediate IL-1 Containing a Caspase Recruitment Domain like Protein - Apoptosis-Associated Speck

Silva, S., Gazzinelli, R. T., Zamboni, D. S., Niz, M. D., Horta, C. V., Silva, G. K., Sesti‐Costa, R., & Nunes, T. A. (2013)

Ion Flux Regulates Inflammasome Signaling

Yaron, J. R. (2015) · doi:10.13140/rg.2.2.32297.60007 · Cited by 1

Peer Review #1 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.1)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.1/reviews/1

Modulação da resposta imune contra Paracoccidioides brasiliensis pelas vias canônica e não canônica do inflamassoma: participação da IL-1β, IL-18 e IL-1α no controle da infecção

Ketelut-Carneiro, N. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2018.tde-08062017-093404

Peer Review #1 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.3)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.3/reviews/1

Peer Review #1 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.2)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.2/reviews/1

Characterizing the Role of IL-1β in Macrophage Clearance of Citrobacter rodentium Infection

Bording‐Jorgensen, M. (2018) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3td9nq61

Electrospinning of Cellulose Based Wound Dressing

Crabbe‐Mann, M. (2019) · UCL Discovery (University College London)

Diabetes Mellitus in California: Complications, Modifiers and Spatial Determinants

Rajan, J. V. (2016) · eScholarship (California Digital Library)

Apoptosis, necroptosis, and pyroptosis in health and disease

Liao, D. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-814208-0.00008-7

Peer Review #3 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.2)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.2/reviews/3

Faculty Opinions recommendation of A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

Fitzgerald, K., & Humphries, F. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.725357852.793560973

Peer Review #3 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.1)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.1/reviews/3

Peer Review #2 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.1)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.1/reviews/2

Peer Review #2 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.2)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.2/reviews/2

Peer Review #4 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.2)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.2/reviews/4

Peer Review #4 of "A strategy to find novel candidate anti-Alzheimer’s disease drugs by constructing interaction networks between drug targets and natural compounds in medical plants (v0.1)"

(2018) · PeerJ · doi:10.7287/peerj.4756v0.1/reviews/4

Suppressive effect of Thymoquinone on NLRP3 pathway in breast cancer: a novel multi-strike CALR and sec-PD-L1 inhibitorPreprint

Elgohary, S., Eissa, R. A., & Tayebi, H. M. E. (2022) · Research Square · doi:10.21203/rs.3.rs-2172339/v1

An anti-inflammatory nanoghost for atherosclerosis therapy: a red blood cell based bio-mimetic strategyPreprint

Karami, Z., Akrami, M., Esfandyari‐Manesh, M., Haririan, I., & Nateghi, S. (2023) · Research Square · doi:10.21203/rs.3.rs-3288904/v1

Crucial Biological Roles of Long Noncoding RNA-Mediated Pyroptosis in Urological Tumors

Xie, J., Jiang, Y., Wang, Y., & He, D. (2023) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2023.3637

Involvement of NLRP3 Inflammasome in SARS-Cov-2-Induced Multiorgan Dysfunction in Patients with COVID-19: A Review of Molecular Mechanisms.

Babazadeh, Z. (2023) · PubMed Central

Role of inflammasomes in HIV-1 and drug abuse-mediated neuroinflammation

Oladapo, A., Chemparathy, D. T., Singh, S., Kannan, M., Buch, S. J., & Periyasamy, P. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99744-7.00020-1

The foodborne toxin perfringolysin O targets mitochondrial destabilization for NLRP3 inflammasome activation

Wang, X., Ren, Y., Wang, B., Han, B., & Xue, Y. (2024) · Food Science and Human Wellness · doi:10.26599/fshw.2024.9250375

Glibenclamide Prevents Inflammation by Targeting NLRP3 Inflammasome Activation In Vitro

Хилажева, Е. Д., Panina, Y. A., Mosiagina, A. I., Belozor, О. S., & Komleva, Y. K. (2024) · Российский физиологический журнал им И М Сеченова · doi:10.31857/s0869813924050067

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of ActionPreprint

Wilhelmsen, K., Deshpande, A., Tronnes, S. U., Mahanta, M., BANICKI, M., COCHRAN, M., Cowdin, S., Fortney, K., Hartman, G. D., Hughes, R. E., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.21.629867

The impact of antidiabetic medications on COVID-19 outcomes in diabetic patients: an overview

Zarei, M., Vaighan, N. S., Shiravand, S., Samani, S. M. V., Sheikholeslami, M. A., & Roudbari, Z. (2024) · Physiology and Pharmacology · doi:10.61186/phypha.28.4.363

Unravelling the impact of NLRP3 inflammasome in fibrosis: Molecular insights into the fibrosis of diverse tissues and potential therapeutic options

Parikh, M., Soni, A., & Gandhi, T. R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-22300-6.00019-x

Carbutamide, an Obsolete Anti-Diabetic Drug, Has Potential as a Potent Anticolitic Agent via Azo-Conjugation with Mesalazine

Ju, S., Kim, S., Kim, T., Yoo, J., Yoon, I., Kim, E., & Jung, Y. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17121509

Additional file 2 of FANCC deficiency mediates microglial pyroptosis and secondary neuronal apoptosis in spinal cord contusion

Xia, M., Li, X., Ye, S., Zhang, Q., Zhao, T., Li, R., Zhang, Y., Xian, M., Li, T., Li, H., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20003476

Additional file 1 of High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages

Mo, Y., Mo, L., Zhang, Y., Zhang, Y., Yuan, J., & Zhang, Q. (2024) · Figshare · doi:10.6084/m9.figshare.26634942

Additional file 2 of High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages

Mo, Y., Mo, L., Zhang, Y., Zhang, Y., Yuan, J., & Zhang, Q. (2024) · Figshare · doi:10.6084/m9.figshare.26634945

Additional file 4 of High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages

Mo, Y., Mo, L., Zhang, Y., Zhang, Y., Yuan, J., & Zhang, Q. (2024) · Figshare · doi:10.6084/m9.figshare.26634951

Additional file 1 of FANCC deficiency mediates microglial pyroptosis and secondary neuronal apoptosis in spinal cord contusion

Xia, M., Li, X., Ye, S., Zhang, Q., Zhao, T., Li, R., Zhang, Y., Xian, M., Li, T., Li, H., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20003473

Additional file 2 of Directly targeting ASC by lonidamine alleviates inflammasome-driven diseases

Chen, C., Zhou, Y., Ning, X., Li, S., Xue, D., Wei, C., Zhu, Z., Sheng, L., Lu, B., Li, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26557931

Additional file 3 of High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages

Mo, Y., Mo, L., Zhang, Y., Zhang, Y., Yuan, J., & Zhang, Q. (2024) · Figshare · doi:10.6084/m9.figshare.26634948

Additional file 5 of High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages

Mo, Y., Mo, L., Zhang, Y., Zhang, Y., Yuan, J., & Zhang, Q. (2024) · Figshare · doi:10.6084/m9.figshare.26634954

Additional file 1 of Directly targeting ASC by lonidamine alleviates inflammasome-driven diseases

Chen, C., Zhou, Y., Ning, X., Li, S., Xue, D., Wei, C., Zhu, Z., Sheng, L., Lu, B., Li, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26557928

NLRP3 Inflammasome Exhibits Context-Dependent Roles in Glioblastoma-Astrocyte CrosstalkPreprint

Rajkhowa, S., Sha, L., Meena, D., Kumar, D., Revanth, M. S., Janu, V. C., Garg, M., Agrawal, M., Jha, D. K., & Jha, S. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.30.697027

Cellular Responses to Stretch Vs. Hydrostatic Pressure

Nagatomi, J. (2025) · Frontiers of biomechanics · doi:10.1007/978-981-95-4405-9_3

NLRP3 Inflammasome and Polycystic Ovary Syndrome (PCOS): A Novel Profile in Adipose Tissue

Alenezi, S. A., Alshammari, K., Khan, R. N., & Amer, S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27020699

Immunometabolic disorders in type 2 diabetes mellitus mediated by NLRP3 inflammasome activation and methods of pharmacological correction thereof

Чепляева, Н. И., Babkov, D. A., Lukyanov, A. V., Danilov, R. D., & Спасов, А. А. (2026) · Problems of Endocrinology · doi:10.14341/probl13590

Immune-targeted therapies: Management of diabetes and fostering healthy aging

Nainu, F., Ophinni, Y., Mamada, S. S., & Latada, N. P. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44665-8.00024-9

Implication de l'inflammasome NLRP3 dans la sécrétion non conventionnelle de la protéine FADD

Mouasni, S. (2018) · theses.fr (ABES) · doi:10.70675/8623f190zbb94z44b7z8b70zd93fa9be484d

Les mécanismes de microvésiculation des cytokines de la famille de l’IL-1

Cambon, A. (2023) · theses.fr (ABES) · doi:10.70675/159070b7za2b7z411fzb52azb56bb6841949

Development of NLRP3 Inflammasome Inhibitors

Blevins, H. (2022) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/wk7f-1g56

Cryopyrin: A Specific Activator of the Inflammasome

(2006) · Science s STKE · doi:10.1126/stke.3262006tw93

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

Jiang, H., He, H., Chen, Y., Huang, W., Cheng, J., Ye, J., Wang, A., Tao, J., Wang, C., Liu, Q., et al. (2017) · The Journal of Experimental Medicine · doi:10.1084/jem.20171419 · Cited by 783

The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and

Inflammasomes, A., Coll, R. C., & O’neill, L. A. J. (2011)

A natural product inhibitor of the NLRP3 inflammasome derived from Glycyrrhiza uralensis for the treatment of inflammatory diseases

Yang, G., Lee, H., Han, S., An, T.-J., Jang, J.-K., & Lee, J. Y. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.198.supp.138.3 · Cited by 3