Dixit, Vishva M.

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 6,680

Death Receptors: Signaling and Modulation

Ashkenazi, A., & Dixit, V. M. (1998) · Science

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 5,866

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Kayagaki, N., Stowe, I. B., Lee, B. L., O’Rourke, K., Anderson, K., Warming, S., Cuellar, T., Haley, B., Roose-Girma, M., Phung, Q. T., et al. (2015) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,686

Inflammasomes: mechanism of assembly, regulation and signalling

Broz, P., & Dixit, V. M. (2016) · Nature Reviews Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,500

Cryopyrin activates the inflammasome in response to toxins and ATP

Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P., Weinrauch, Y., Monack, D. M., & Dixit, V. M. (2006) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,080

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., et al. (1996) · Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 3,046

Non-canonical inflammasome activation targets caspase-11

Kayagaki, N., Warming, S., Lamkanfi, M., Walle, L. V., Louie, S., Dong, J., Newton, K., Qu, Y., Liu, J., Heldens, S., et al. (2011) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,530

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

Chinnaiyan, A. M., O'Rourke, K., Tewari, M., & Dixit, V. M. (1995) · Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 2,431

Signaling in innate immunity and inflammation

Newton, K., & Dixit, V. M. (2012) · Cold Spring Harbor Perspectives in Biology

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 1,513

IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis

Varfolomeev, E., Blankenship, J. W., Wayson, S. M., Fedorova, A. V., Kayagaki, N., Garg, P., Zobel, K., Dynek, J. N., Elliott, L. O., Wallweber, H. J. A., et al. (2007) · Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 1,218

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 1,002

Inflammasomes and Their Roles in Health and Disease

Lamkanfi, M., & Dixit, V. M. (2012) · Annual Review of Cell and Developmental Biology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 935

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

Aglietti, R. A., Estevez, A., Gupta, A., Ramirez, M. G., Liu, P. S., Kayagaki, N., Ciferri, C., Dixit, V. M., & Dueber, E. C. (2016) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 898

NINJ1 mediates plasma membrane rupture during lytic cell death

Kayagaki, N., Kornfeld, O. S., Lee, B. L., Stowe, I. B., O’Rourke, K., Li, Q., Sandoval, W., Yan, D., Kang, J., Xu, M., et al. (2021) · Nature

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 857

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

Lamkanfi, M., Mueller, J. L., Vitari, A. C., Misaghi, S., Fedorova, A., Deshayes, K., Lee, W. P., Hoffman, H. M., & Dixit, V. M. (2009) · Journal of Cell Biology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 820

Mitochondrial reactive oxygen species drive proinflammatory cytokine production

Naik, E., & Dixit, V. M. (2011) · Journal of Experimental Medicine

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 783

Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

Newton, K., Dugger, D. L., Wickliffe, K. E., Kapoor, N., de Almagro, M. C., Vucic, D., Komuves, L., Ferrando, R. E., French, D. M., Webster, J., et al. (2014) · Science

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 687

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

Schwickart, M., Huang, X., Lill, J. R., Liu, J., Ferrando, R., French, D. M., Maecker, H., O’Rourke, K., Bazan, F., Eastham-Anderson, J., et al. (2010) · Nature

Ubiquitin and proteasome pathwaysCell death mechanisms and regulation

Cited by 628

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella

Broz, P., Newton, K., Lamkanfi, M., Mariathasan, S., Dixit, V. M., & Monack, D. M. (2010) · Journal of Experimental Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 549

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

Broz, P., Ruby, T., Belhocine, K., Bouley, D. M., Kayagaki, N., Dixit, V. M., & Monack, D. M. (2012) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 535

Caspase-9 Can Be Activated without Proteolytic Processing

Stennicke, H. R., Deveraux, Q. L., Humke, E. W., Reed, J. C., Dixit, V. M., & Salvesen, G. S. (1999) · Journal of Biological Chemistry

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 497

Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements.

Krikos, A., Laherty, C. D., & Dixit, V. M. (1992) · Journal of Biological Chemistry

NF-κB Signaling PathwaysGenomics and Chromatin Dynamics

Cited by 444

Drugging the undruggables: exploring the ubiquitin system for drug development

Huang, X., & Dixit, V. M. (2016) · Cell Research

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 427

RIPK1 inhibits ZBP1-driven necroptosis during development

Newton, K., Wickliffe, K. E., Maltzman, A., Dugger, D. L., Strasser, A., Pham, V. C., Lill, J. R., Roose-Girma, M., Warming, S., Solon, M., et al. (2016) · Nature

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 390