Microglia in Alzheimer’s disease

Hansen, David V., Hanson, Jesse E., Sheng, Morgan·2018·Journal of Cell Biology

Cited by (1,016)

Items 101–200 of 1,016

  1. Physical activity for cognitive health promotion: An overview of the underlying neurobiological mechanisms
    Chong Chen, Shin Nakagawa · 2023 · Ageing Research Reviews
  2. Human iPSC‐derived microglia: A growing toolset to study the brain's innate immune cells
    Hasselmann, Jonathan, Blurton‐Jones, Mathew · 2020 · Glia
  3. CD4+ effector T cells accelerate Alzheimer’s disease in mice
    Jatin Machhi, Pravin Yeapuri, Yaman Lu, Emma G. Foster, Rupesh V. Chikhale, Jonathan Herskovitz, Krista L. Namminga, Katherine E. Olson, Mai Mohamed Abdelmoaty, Ju Gao et al. · 2021 · Journal of Neuroinflammation
  4. Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease
    Minghui Wang, Hu Zhang, Jiling Liang, Jielun Huang, Ning Chen · 2023 · Journal of Neuroinflammation
  5. An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments
    Keliang Pang, Richeng Jiang, Wei Zhang, Zhengyi Yang, Linlin Li, Makoto Shimozawa, Simone Tambaro, Johanna Mayer, Baogui Zhang, Man Li et al. · 2021 · Cell Research
  6. An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains
    Millet, Alon, Ledo, Jose Henrique, Tavazoie, Sohail F. · 2024 · Immunity
  7. The Emerging Role of Central and Peripheral Immune Systems in Neurodegenerative Diseases
    Zang, Xin, Chen, Si, Zhu, JunYao, Ma, Junwen, Zhai, Yongzhen · 2022 · Frontiers in Aging Neuroscience
  8. Metabolic reprogramming in inflammatory microglia indicates a potential way of targeting inflammation in Alzheimer's disease
    Sangineto, Moris, Ciarnelli, Martina, Cassano, Tommaso, Radesco, Antonio, Moola, Archana, Bukke, Vidyasagar Naik, Romano, Antonino, Villani, Rosanna, Kanwal, Hina, Capitanio, Nazzareno et al. · 2023 · Redox Biology
  9. Protein acetylation and deacetylation: An important regulatory modification in gene transcription (Review)
    Xia, Can, Tao, Yu, Li, Mingshan, Che, Tuanjie, Qu, Jing · 2020 · Experimental and Therapeutic Medicine
  10. Astrocyte metabolism and signaling pathways in the CNS
    Yong-Mei Zhang, Yingbei Qi, Ya-nan Gao, Wen-gang Chen, Ting Zhou, Yi Zang, Jia Xuan Li · 2023 · Frontiers in Neuroscience
  11. Transcriptional and Epigenetic Regulation of Microglia in Health and Disease
    Yeh, Hana, Ikezu, Tsuneya · 2019 · Trends in Molecular Medicine
  12. Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer’s disease mouse model
    Lechan Tao, Qi Liu, Fuli Zhang, Yuting Fu, Xi De Zhu, Xiaofu Weng, Hongbin Han, Yong Huang, Yuanzhen Suo, Liang Chen et al. · 2021 · Light Science & Applications
  13. The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease: a narrative review.
    Emma Aaldijk, Yannick Vermeiren · 2022 · Ageing Research Reviews
  14. Soluble TREM2: Innocent bystander or active player in neurological diseases?
    Filipello, Fabia, Goldsbury, Claire, You, Shih Feng, Locca, Alberto, Karch, Celeste M., Piccio, Laura · 2022 · Neurobiology of Disease
  15. Involvement of extrasynaptic glutamate in physiological and pathophysiological changes of neuronal excitability
    Balázs Zoltán Pál · 2018 · Cellular and Molecular Life Sciences
  16. Cholinergic Modulation of Glial Function During Aging and Chronic Neuroinflammation
    Rashmi Vasundhara Gamage, Ingrid Marguerite Wagnon, Ilaria Rossetti, Ryan Childs, Garry Niedermayer, Rose Chesworth, Erika Gyengési · 2020 · Frontiers in Cellular Neuroscience
  17. Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the 5XFAD Alzheimer's Disease Model
    Qian Shi, Cheng Chang, Afaf Saliba, Manzoor A. Bhat · 2022 · Journal of Neuroscience
  18. Developing Effective Alzheimer’s Disease Therapies: Clinical Experience and Future Directions
    Elmaleh, David R., Farlow, Martin R., Conti, Peter S., Tompkins, Ronald G., Kundakovic, Ljiljana, Tanzi, Rudolph E. · 2019 · Journal of Alzheimer’s Disease
  19. Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease
    Fitz, Nicholas F., Nam, Kyong Nyon, Wolfe, Cody M., Letronne, Florent, Playso, Brittany E., Iordanova, Bistra E., Kozai, Takashi D. Y., Biedrzycki, Richard J., Kagan, Valerian E., Tyurina, Yulia Y. et al. · 2021 · Nature Communications
  20. Current understanding of the cGAS-STING signaling pathway: Structure, regulatory mechanisms, and related diseases
    Jing Pan, 宁波大学农产品质量安全危害因子与风险防控国家重点实验室, 浙江 宁波 315211, 中国, Chen-Jie Fei, Yang Hu, Xiangyu Wu, Li Nie, Jiong Chen, 宁波大学梅山校区海洋学院生物化学与分子生物学实验室, 浙江 宁波 315832, 中国, 浙江省海洋生物工程重点实验室, 浙江 宁波 315832, 中国 · 2023 · 动物学研究
  21. DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
    Gemma L. Shireby, Emma Louise Dempster, Stefania S S Policicchio, Rebecca G. Smith, Ehsan Pishva, Barry A. Chioza, Jonathan P. Davies, Joe Burrage, Katie Lunnon, Dorothea Seiler Vellame et al. · 2022 · Nature Communications
  22. Neurodegeneration and Neuro-Regeneration—Alzheimer’s Disease and Stem Cell Therapy
    Verica Vasić, Kathrin Barth, Mirko H. H. Schmidt · 2019 · International Journal of Molecular Sciences
  23. Microglial phagocytosis in aging and Alzheimer's disease
    Gabandé‐Rodríguez, Enrique, Keane, Lily, Capasso, Melania · 2020 · Journal of Neuroscience Research
  24. The role of membrane trafficking in the processing of amyloid precursor protein and production of amyloid peptides in Alzheimer's disease
    Jing Zhi Anson Tan, Paul A. Gleeson · 2019 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  25. Neurovascular Coupling in Development and Disease: Focus on Astrocytes
    Teresa L. Stackhouse, Anusha Mishra · 2021 · Frontiers in Cell and Developmental Biology
  26. Alzheimer's disease: Updated multi-targets therapeutics are in clinical and in progress
    Zhipei Sang, Keren Wang, Jianghong Dong, Lei Tang · 2022 · European Journal of Medicinal Chemistry
  27. Roles of Neuropeptide Y in Neurodegenerative and Neuroimmune Diseases
    Chun-Rong Li, Xiu-Juan Wu, Shan Liu, Yue Zhao, Jie Zhu, Kang-Ding Liu · 2019 · Frontiers in Neuroscience
  28. COVID‐19‐related neuropathology and microglial activation in elderly with and without dementia
    Tino Emanuele Poloni, Valentina Medici, Matteo Moretti, Silvia Damiana Visoná, Alice Cirrincione, Arenn F. Carlos, Annalisa Davin, Stella Gagliardi, Orietta Pansarasa, Cristina Cereda et al. · 2021 · Brain Pathology
  29. The mechanism and efficacy of GLP-1 receptor agonists in the treatment of Alzheimer’s disease
    Du, Haiyang, Meng, Xiaoyu, Yao, Yu, Xu, Jun · 2022 · Frontiers in Endocrinology
  30. Potential Bidirectional Relationship Between Periodontitis and Alzheimer’s Disease
    Daniela Liccardo, Federica Marzano, Federica Carraturo, Marco Guida, Grazia Daniela Femminella, Leonardo Bencivenga, Jacopo Agrimi, Armida Addonizio, Imma Melino, Alessandra Valletta et al. · 2020 · Frontiers in Physiology
  31. The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice
    Young, Melissa L., Franklin, James L. · 2019 · Molecular and Cellular Neuroscience
  32. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia
    Xia, Dan, Lianoglou, Steve, Sandmann, Thomas, Calvert, Meredith, Suh, Jung H., Thomsen, Elliot, Dugas, Jason, Pizzo, Michelle E., DeVos, Sarah L., Earr, Timothy K. et al. · 2022 · Molecular Neurodegeneration
  33. Leveraging preclinical models for the development of Alzheimer disease therapeutics
    Kimberly A. Scearce-Levie, Pascal E. Sanchez, Joseph W. Lewcock · 2020 · Nature Reviews Drug Discovery
  34. Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer’s Disease, Parkinson’s Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome
    T. Satoh, D. Trudler, Chang-ki Oh, S. Lipton · 2022 · Antioxidants
  35. TLR4 Targeting as a Promising Therapeutic Strategy for Alzheimer Disease Treatment
    Yongji Zhou, Yanxing Chen, Congcong Xu, Hao Zhang, Caixiu Lin · 2020 · Frontiers in Neuroscience
  36. Microbial involvement in Alzheimer disease development and progression
    Bulgart, Hannah R., Neczypor, Evan W., Wold, Loren E., Mackos, Amy R. · 2020 · Molecular Neurodegeneration
  37. Mitochondrial dysfunctions, oxidative stress and neuroinflammation as therapeutic targets for neurodegenerative diseases: An update on current advances and impediments
    Rehman, Muneeb U., Sehar, Nouroz, Dar, Nawab John, Khan, Andleeb, Arafah, Azher, Rashid, Summya, Rashid, Shahzada Mudasir, Ganaie, Majid Ahmad · 2023 · Neuroscience & Biobehavioral Reviews
  38. The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review
    Hossein Bagheri, Faezeh Ghasemi, George Emilio Barreto, Thozhukat Sathyapalan, Tannaz Jamialahmadi, Amirhossein Sahebkar · 2019 · BioFactors
  39. Cortical excitability and plasticity in Alzheimer’s disease and mild cognitive impairment: A systematic review and meta-analysis of transcranial magnetic stimulation studies
    Ying‐hui Chou, Mark Sundman, Viet Ton That, Jacob Green, Chrisopher Trapani · 2022 · Ageing Research Reviews
  40. Microglial morphometric analysis: so many options, so little consistency
    Jack Reddaway, Peter Richardson, Ryan J. Bevan, Jessica Stoneman, Marco Palombo · 2023 · Frontiers in Neuroinformatics
  41. Cell Death and Neurodegeneration
    Benjamin J. Andreone, Martin Larhammar, Joseph W. Lewcock · 2019 · Cold Spring Harbor Perspectives in Biology
  42. Recent Advances in the Treatment of Alzheimer’s Disease Using Nanoparticle-Based Drug Delivery Systems
    Poudel, Prashant, Park, Soyeun · 2022 · Pharmaceutics
  43. Gut microbiota–driven brain Aβ amyloidosis in mice requires microglia
    Dodiya, Hemraj B., Lutz, Holly L., Weigle, Ian Q., Patel, Priyam, Michalkiewicz, Julia, Roman-Santiago, Carlos J., Zhang, Can Martin, Liang, Yingxia, Srinath, Abhinav, Zhang, Xulun et al. · 2022 · Journal of Experimental Medicine
  44. The Role of TNF-α in Alzheimer’s Disease: A Narrative Review
    Domenico Plantone, Matteo Pardini, Delia Righi, Carlo Manco, Barbara Maria Colombo, Nicola De Stefano · 2023 · Cells
  45. IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease
    Lau, Shun-Fat, Chen, Congping, Fu, Wing-Yu, Qu, Jianan Y., Cheung, Tom H., Fu, Amy K.Y., Ip, Nancy Y. · 2020 · Cell Reports
  46. Immune Response in Neurological Pathology: Emerging Role of Central and Peripheral Immune Crosstalk
    Austin P. Passaro, Abraham L. Lebos, Yao Yao, Steven L. Stice · 2021 · Frontiers in Immunology
  47. Microglia-Astrocyte Communication in Alzheimer’s Disease
    Yingying Wu, Ulrich L.M. Eisel · 2023 · Journal of Alzheimer s Disease
  48. Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia
    Hao Han, Yawei Zhao, Junda Du, Sushan Wang, Xuehan Yang, Weijie Li, Jiayi Song, Siwei Zhang, Ziyi Zhang, Yongfei Tan et al. · 2023 · Immunity & Ageing
  49. Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders
    Jinming Han, Keying Zhu, Xing‐Mei Zhang, Robert Adam Harris · 2018 · Glia
  50. Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model
    Zhang, Yuanyue, Fung, Ivan Ting Hin, Sankar, Poornima, Chen, Xiangyu, Robison, Lisa S, Ye, Longyun, D’Souza, Shanti S, Salinero, Abigail E, Kuentzel, Marcy L, Chittur, Sridar V et al. · 2020 · The Journal of Immunology
  51. Microglial efferocytosis: Diving into the Alzheimer’s disease gene pool
    Romero-Molina, Carmen, Garretti, Francesca, Andrews, Shea J., Marcora, Edoardo, Goate, Alison M. · 2022 · Neuron
  52. ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans
    Conway, Olivia J, Carrasquillo, Minerva M, Wang, Xue, Bredenberg, Jenny M, Reddy, Joseph S, Strickland, Samantha L, Younkin, Curtis S, Burgess, Jeremy D, Allen, Mariet, Lincoln, Sarah J et al. · 2018 · Molecular Neurodegeneration
  53. Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets
    Mariana Y. García-Bermúdez, Kristine Freude, Zaynab Ahmad Mouhammad, Peter van Wijngaarden, K. Martin, Miriam Kolko · 2021 · Frontiers in Neurology
  54. VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice
    El Gaamouch, Farida, Audrain, Mickael, Lin, Wei-Jye, Beckmann, Noam, Jiang, Cheng, Hariharan, Siddharth, Heeger, Peter S., Schadt, Eric E., Gandy, Sam, Ehrlich, Michelle E. et al. · 2020 · Molecular Neurodegeneration
  55. TGF-β1 signalling in Alzheimer’s pathology and cytoskeletal reorganization: a specialized Tau perspective
    Mahima Kapoor, Subashchandrabose Chinnathambi · 2023 · Journal of Neuroinflammation
  56. The Crucial Role of the Blood–Brain Barrier in Neurodegenerative Diseases: Mechanisms of Disruption and Therapeutic Implications
    Sehwan Kim, Un Ju Jung, Sang Ryong Kim · 2025 · Journal of Clinical Medicine
  57. TSPO Modulates IL-4-Induced Microglia/Macrophage M2 Polarization via PPAR-γ Pathway
    Dandan Zhou, Lei Ji, Youguo Chen · 2019 · Journal of Molecular Neuroscience
  58. Masitinib for mild-to-moderate Alzheimer’s disease: results from a randomized, placebo-controlled, phase 3, clinical trial
    Bruno Dubois, Jesús López‐Arrieta, Stanley Lipschitz, Triantafyllos K. Doskas, Luiza Spiru, Svitlana Moroz, Olena Venger, Patrick Vermersch, Alain Moussy, Colin D. Mansfield et al. · 2023 · Alzheimer s Research & Therapy
  59. Ubiquitous protein lactylation in health and diseases
    Junyong Wang, Ziyi Wang, Qixu Wang, Xiao Li, Yaping Guo · 2024 · Cellular & Molecular Biology Letters
  60. Microglial activation in early Alzheimer trajectory is associated with higher gray matter volume
    Grazia Daniela Femminella, Melanie Dani, Melanie Wood, Zhen Fan, Valeria Calsolaro, Rebecca Atkinson, Trudi L. Edginton, Rainer Hinz, David James Brooks, Paul Edison · 2019 · Neurology
  61. The relationship between inflammation, impaired glymphatic system, and neurodegenerative disorders: A vicious cycle
    Yu Cai, Yangqiqi Zhang, Shuo Leng, Yuanyuan Ma, Quan Jiang, Qiuting Wen, Shenghong Ju, Jiani Hu · 2024 · Neurobiology of Disease
  62. Gut Microbiota: From the Forgotten Organ to a Potential Key Player in the Pathology of Alzheimer’s Disease
    Dong-oh Seo, David M. Holtzman · 2019 · The Journals of Gerontology Series A
  63. Roles of Selenoproteins in Brain Function and the Potential Mechanism of Selenium in Alzheimer’s Disease
    Zhonghao Zhang, Guoli Song · 2021 · Frontiers in Neuroscience
  64. RETRACTED: Deciphering the Potential Neuroprotective Effects of Luteolin against Aβ1–42-Induced Alzheimer’s Disease
    Sareer Ahmad, Myeung Hoon Jo, Muhammad Aimen Ikram, Amjad Khan, Myeong Ok Kim · 2021 · International Journal of Molecular Sciences · Retracted
  65. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia
    Ari Sudwarts, Supriya Ramesha, Tianwen Gao, Moorthi Ponnusamy, Shuai Wang, Mitchell T. Hansen, Alena Kozlova, Sara Bitarafan, Prateek Kumar, David Beaulieu‐Abdelahad et al. · 2022 · Molecular Neurodegeneration
  66. Alzheimer’s disease beyond amyloid: Can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?
    Kevin Mullane, Michael J. Williams · 2020 · Biochemical Pharmacology
  67. Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer's disease
    Deborah O T Alawode, Amanda Heslegrave, Nicholas James Ashton, Thomas K. Karikari, Joel Simrén, Laia Montoliu‐Gaya, Josef Pannee, Antoinette O’Connor, Philip S.J. Weston, Juan Lantero‐Rodriguez et al. · 2021 · Journal of Internal Medicine
  68. Gastrodin regulates the TLR4/TRAF6/NF-κB pathway to reduce neuroinflammation and microglial activation in an AD model
    Wensheng Wang, Yu Wang, Yu Wang, Guangjing Xie, Shangzhi Liu, Zefei Li, Ping Wang, Junfeng Liu, Lin Li · 2024 · Phytomedicine
  69. A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse
    Min Sung Gee, Seung Hwan Son, Seung Ho Jeon, Jimin Do, Namkwon Kim, Yeon‐Joo Ju, Soo Jin Lee, Eun Kyoung Chung, Kyung‐Soo Inn, Nam‐Jung Kim et al. · 2020 · Alzheimer s Research & Therapy
  70. Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis
    Kaji, Seiji, Berghoff, Stefan A., Spieth, Lena, Schlaphoff, Lennart, Sasmita, Andrew O., Vitale, Simona, Büschgens, Luca, Kedia, Shreeya, Zirngibl, Martin, Nazarenko, Taisiia et al. · 2024 · Immunity
  71. A comparative analysis of microglial inducible Cre lines
    Faust, Travis E., Feinberg, Philip A., O’Connor, Ciara, Kawaguchi, Riki, Chan, Andrew, Strasburger, Hayley, Frosch, Maximilian, Boyle, Margaret A., Masuda, Takahiro, Amann, Lukas et al. · 2023 · Cell Reports
  72. Restoring Oat Nanoparticles Mediated Brain Memory Function of Mice Fed Alcohol by Sorting Inflammatory Dectin‐1 Complex Into Microglial Exosomes
    Fangyi Xu, Jingyao Mu, Yun Teng, Xiangcheng Zhang, Kumaran Sundaram, Mukesh K. Sriwastva, Anil Kumar, Chao Lei, Lifeng Zhang, Qiaohong M. Liu et al. · 2021 · Small
  73. Microglial Metabolic Reprogramming: Emerging Insights and Therapeutic Strategies in Neurodegenerative Diseases
    Jifei Miao, Lihua Chen, Xiaojin Pan, Li-qing Li, Beibei Zhao, Jiao Xia Lan · 2023 · Cellular and Molecular Neurobiology
  74. The dual face of microglia (M1/M2) as a potential target in the protective effect of nutraceuticals against neurodegenerative diseases
    Samar F. Darwish, Abdullah M. M. Elbadry, Amir S. Elbokhomy, Ghidaa A. Salama, Rania M. Salama · 2023 · Frontiers in Aging
  75. Alzheimer's disease pathophysiology in the Retina
    Bhakta Prasad Gaire, Yosef Koronyo, Dieu-Trang S. Fuchs, Haoshen Shi, Altan Rentsendorj, Ron Danziger, Jean‐Philippe Vit, Nazanin Mirzaei, Jonah Doustar, Julia Sheyn et al. · 2024 · Progress in Retinal and Eye Research
  76. Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids
    Martin Barák, Veronika Fedorová, Veronika Pospíšilová, Jan Raška, Simona Vochyánová, Jiří Sedmík, Hana Hříbková, Hana Klímová, Tereza Váňová, Dáša Bohačiaková · 2022 · Stem Cell Reviews and Reports
  77. Microglia and Astrocytes in Alzheimer’s Disease: Significance and Summary of Recent Advances
    Deng, Qianting, Wu, Chongyun, Parker, Emily, Liu, Timon Cheng-Yi, Duan, Rui, Yang, Luodan · 2023 · Aging and disease
  78. An overview of the relationship between inflammation and cognitive function in humans, molecular pathways and the impact of nutraceuticals
    Chusana Mekhora, Daniel Joseph Lamport, Jeremy P.E. Spencer · 2024 · Neurochemistry International
  79. Alzheimer’s Disease and Inflammaging
    Kosyreva, Anna, Sentyabreva, Alexandra, Tsvetkov, Ivan, Makarova, Olga · 2022 · Brain Sciences
  80. Microglia responses to interleukin‐6 and type I interferons in neuroinflammatory disease
    Phillip K. West, Barney Viengkhou, Iain Leslie Campbell, Markus J. Hofer · 2019 · Glia
  81. Interaction of Tau with the chemokine receptor, CX3CR1 and its effect on microglial activation, migration and proliferation
    Hariharakrishnan Chidambaram, Rashmi Ranjan Das, Subashchandrabose Chinnathambi · 2020 · Cell & Bioscience
  82. The Role of Microglia in Alzheimer’s Disease From the Perspective of Immune Inflammation and Iron Metabolism
    Hui-Zhi Long, Zi-Wei Zhou, Yan Cheng, Hong-Yu Luo, Feng-Jiao Li, Shuoxi Xu, Li-Chen Gao · 2022 · Frontiers in Aging Neuroscience
  83. Inhibition of Bruton's Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer's Disease
    Keaney, James, Gasser, Julien, Gillet, Gaëlle, Scholz, Diana, Kadiu, Irena · 2019 · Journal of Neuroimmune Pharmacology
  84. Fecal microbiota transplantation ameliorates stress-induced depression-like behaviors associated with the inhibition of glial and NLRP3 inflammasome in rat brain
    Jingjing Rao, Yi Qiao, Ruining Xie, Li Lin, Jian Hong Jiang, Chunmei Wang, Gongying Li · 2021 · Journal of Psychiatric Research
  85. Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer’s disease
    Terzioglu, Gizem, Young-Pearse, Tracy L. · 2023 · Molecular Neurodegeneration
  86. Harnessing endophenotypes and network medicine for Alzheimer's drug repurposing
    Jiansong Fang, Andrew A. Pieper, Ruth Nussinov, Garam Lee, Lynn M. Bekris, James B. Leverenz, Jeffrey L. Cummings, Feixiong Cheng · 2020 · Medicinal Research Reviews
  87. Emerging role of mesenchymal stromal cells (MSCs)-derived exosome in neurodegeneration-associated conditions: a groundbreaking cell-free approach
    Hadi Yari, Maria V. Mikhailova, Mahsa Mardasi, Mohsen Jafarzadehgharehziaaddin, Somayeh Shahrokh, Lakshmi Prasanth Thangavelu, Hosein Ahmadi, Navid Shomali, Yoda Yaghoubi, Majid Zamani et al. · 2022 · Stem Cell Research & Therapy
  88. Evaluation of CD33 as a genetic risk factor for Alzheimer’s disease
    Steven Estus, Benjamin C. Shaw, Nicholas A. Devanney, Yuriko Katsumata, Eileen Press, David W. Fardo · 2019 · Acta Neuropathologica
  89. Genomics of Alzheimer’s disease implicates the innate and adaptive immune systems
    Yihan Li, Simon Matthew Laws, Luke A. Miles, James S. Wiley, Xin Huang, Colin Louis Masters, Ben J. Gu · 2021 · Cellular and Molecular Life Sciences
  90. The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease
    Moutinho, Miguel, Puntambekar, Shweta S., Tsai, Andy P., Coronel, Israel, Lin, Peter B., Casali, Brad T., Martinez, Pablo, Oblak, Adrian L., Lasagna-Reeves, Cristian A., Lamb, Bruce T. et al. · 2022 · Science Translational Medicine
  91. High frequency repetitive transcranial magnetic stimulation alleviates cognitive deficits in 3xTg-AD mice by modulating the PI3K/Akt/GLT-1 axis
    Huấn Cao, Chengchao Zuo, Zhongya Gu, Yaqi Huang, Yuyan Yang, Liudi Zhu, Yongsheng Jiang, Furong Wang · 2022 · Redox Biology
  92. Deep autoencoder for interpretable tissue-adaptive deconvolution and cell-type-specific gene analysis
    Yanshuo Chen, Yixuan Wang, Yuelong Chen, Yuqi Cheng, Yumeng Wei, Yunxiang Li, Jiuming Wang, Yingying Wei, Ting‐Fung Chan, Yu Li · 2022 · Nature Communications
  93. Trilobatin rescues cognitive impairment of Alzheimer’s disease by targeting HMGB1 through mediating SIRT3/SOD2 signaling pathway
    Jian-mei Gao, Xun Zhang, Guotao Shu, Nana Chen, Jianyong Zhang, Fan Xu, Fei Li, Yuangui Liu, Yu Wei, Yuqi He et al. · 2022 · Acta Pharmacologica Sinica
  94. <scp>TREM2</scp>‐induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology
    Fracassi, Anna, Marcatti, Michela, Tumurbaatar, Batbayar, Woltjer, Randall, Moreno, Sandra, Taglialatela, Giulio · 2023 · Brain Pathology
  95. Adipose tissue, systematic inflammation, and neurodegenerative diseases
    Ludovico Migliolo, Ana Paula de Araújo Boleti, Pedro Henrique de Oliveira Cardoso, Breno Emanuel Farias Frihling, Patrícia Souza e Silva, Luiz Filipe Ramalho Nunes de Moraes · 2022 · Neural Regeneration Research
  96. Exploring the microbiota-Alzheimer’s disease linkage using short-term antibiotic treatment followed by fecal microbiota transplantation
    Min Wang, Jianing Cao, Congcong Gong, William Kwame Amakye, Maojin Yao, Jiaoyan Ren · 2021 · Brain Behavior and Immunity
  97. Evidence for the Role of Mitochondrial DNA Release in the Inflammatory Response in Neurological Disorders
    Gonzalo E. Moya, Phillip D. Rivera, Kristin E. Dittenhafer‐Reed · 2021 · International Journal of Molecular Sciences
  98. A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain
    Lihong Zhan, Li Fan, Lay Kodama, Peter Sohn, Man Ying Wong, Gergey Alzaem Mousa, Yungui Zhou, Yaqiao Li, Li Gan · 2020 · eLife
  99. Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer’s Disease
    Linyu Wu, Xiao‐Hui Xian, Guangyu Xu, Zixuan Tan, Fang Dong, Min Zhang, Feng Zhang · 2022 · Mediators of Inflammation
  100. Shifting paradigms: The central role of microglia in Alzheimer’s disease
    Schwabe, Tina, Srinivasan, Karpagam, Rhinn, Herve · 2020 · Neurobiology of Disease