The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor.
Open accessAbstract
The recent molecular cloning of the complementary DNA encoding T cell--replacing factor (TRF) has demonstrated that a single molecule is responsible for B cell growth factor II (BCGF-II) activity and eosinophil differentiation activity. It has been proposed that this molecule be called interleukin 5 (IL-5). We previously reported that purified rIL-5 supports the terminal differentiation and proliferation of eosinophilic precursors. In this study, we examined the effects of IL-5 on functional activities of mature eosinophils. IL-5 maintained the viability of mature eosinophils obtained from peritoneal exudate cells of mice infected with parasites. It also induced superoxide anion production in a dose-dependent manner. The Boyden's chamber Millipore assay revealed that IL-5 had a marked chemokinetic effect on eosinophils in a dose-dependent manner. Moreover, IL-5 was found to be an eosinophil chemotactic factor by the checkerboard assay. In conclusion, IL-5 is suggested to play an important role in increasing the functional activities of eosinophils as well as their production in allergic and parasitic diseases.
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Citations
Cites
LEUKOCYTE LOCOMOTION AND CHEMOTAXIS
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Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor
Nagata, S., Tsuchiya, M., Asano, S., Kaziro, Y., Yamazaki, T., Yamamoto, O., Hirata, Y., Kubota, N., Oheda, M., Nomura, H., et al. (1986) · Nature · doi:10.1038/319415a0 · Cited by 812
Yamaguchi, Y., Suda, T., Suda, J., Eguchi, M., Miura, Y., Harada, N., Tominaga, A., & Takatsu, K. (1988) · The Journal of experimental medicine · doi:10.1084/jem.167.1.43 · Cited by 514
Self-citationTHE ROLE OF SERUM COMPLEMENT IN CHEMOTAXIS OF LEUKOCYTES IN VITRO
Ward, P. A., Cochrane, C. G., & Müller-Eberhard, H. J. (1965) · The Journal of Experimental Medicine · doi:10.1084/jem.122.2.327 · Cited by 400
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Yokota, T., Coffman, R. L., Hagiwara, H., Rennick, D. M., Takebe, Y., Yokota, K., Gemmell, L., Shrader, B., Yang, G., & Meyerson, P. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.21.7388 · Cited by 230
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Self-citationHarada, N., Takahashi, T., Matsumoto, M., Kinashi, T., Ohara, J., Kikuchi, Y., Koyama, N., Gronowicz, E. S., Yaoita, Y., & Honjo, T. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.13.4581 · Cited by 86
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A role for eosinophils in airway remodelling in asthma
Kay, A. B., Phipps, S., & Robinson, D. S. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.07.006 · Cited by 320
Yamaguchi, Y., Suda, T., Ohta, S., Tominaga, K., Miura, Y., & Kasahara, T. (1991) · Blood · doi:10.1182/blood.v78.10.2542.2542 · Cited by 308
Self-citationYamaguchi, Y., Ackerman, S. J., Minegishi, N., Takiguchi, M., Yamamoto, M., & Suda, T. (1998) · Blood · doi:10.1182/blood.v91.9.3447 · Cited by 64
Self-citationCalderón, M. A., Lozewicz, S., Prior, A., Jordan, S., Trigg, C. J., & Davies, R. J. (1994) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(94)70075-3 · Cited by 58
Colonization and effector functions of innate lymphoid cells in mucosal tissues
Kim, M., & Kim, C. H. (2016) · Microbes and Infection · doi:10.1016/j.micinf.2016.06.005 · Cited by 16
Metadata
- Authors
- Yamaguchi, Y., Hayashi, Y., Sugama, Y., Miura, Y., Kasahara, T., Kitamura, S., Torisu, M., Mita, S., Tominaga, A., & Takatsu, K.
- Venue
- The Journal of experimental medicine
- Publisher
- Rockefeller University Press
- Published
- 1988-05-01
- Volume
- 167
- Issue
- 5
- Pages
- 1737-1742
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2060543236
- Cited by
- 608
- References
- 11
- FWCI
- 17.90
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Yamaguchi, Y., Hayashi, Y., Sugama, Y., Miura, Y., Kasahara, T., Kitamura, S., Torisu, M., Mita, S., Tominaga, A., & Takatsu, K. (1988). Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor. The Journal of experimental medicine. https://doi.org/10.1084/jem.167.5.1737
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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