Fungal Infections in Patients with Severe Acute Pancreatitis and the Use of Prophylactic Therapy
Abstract
Data from an 8-year period for 46 patients with severe acute pancreatitis and infected pancreatic necrosis were analyzed to determine the incidence of fungal infection, to identify risk factors for the development of fungal infection, and to assess the use of early fluconazole treatment. Intraabdominal fungal infection was found in 17 (37%) of 46 patients. Candida albicans was isolated most frequently (15 patients); Candida tropicalis and Candida krusei were found in 1 patient each. Characteristics of patients with fungal infection were not different from patients without fungal infection. The difference in mortality was not statistically significant between patients with fungal infection and patients without fungal infection. Early antifungal therapy (prophylactic or preemptive antifungal therapy) was administered to 18 patients, and only 3 of them developed fungal infection. In this cohort of critically ill patients, no risk factors for fungal infection could be demonstrated, and mortality among patients who received early antifungal therapy was not different. Early treatment with fluconazole seems to prevent fungal infection in these high-risk patients.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In SICU patients with severe acute pancreatitis, those who developed invasive candidiasis could not be differentiated from those who did not by classical parameters such as Apache II score or previous antibiotic treatment.
“in one study, surgical ICU (SICU) patients with severe acute pancreatitis who did develop invasive candidiasis could not be differentiated from those who did not become infected when evaluated according to classical parameters such as Apache II score or previous antibiotic treatment [37].”
From Management of invasive candidiasis and candidemia in adult non-neutropenic intensive care unit patients: part I. Epidemiology and diagnosis (2009) · cites this paper as [37]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
A Clinically Based Classification System for Acute Pancreatitis
Bradley, E. L. (1993) · Archives of Surgery · doi:10.1001/archsurg.1993.01420170122019 · Cited by 2,769 · see citing works
Candida Colonization and Subsequent Infections in Critically III Surgical Patients
Pittet, D., Monod, M., Suter, P. M., Frenk, E., & Auckenthaler, R. (1994) · Annals of Surgery · doi:10.1097/00000658-199412000-00008 · Cited by 798 · see citing works
IAP Guidelines for the Surgical Management of Acute Pancreatitis
Uhl, W. H., Warshaw, A. L., IMRIE, C. W., Bassi, C., McKay, C. J., Lankisch, P. G., Carter, R., Magno, E. D., Banks, P. A., Whitcomb, D. C., et al. (2002) · Pancreatology · doi:10.1159/000071269 · Cited by 774 · see citing works
Candidemia in a tertiary care hospital: epidemiology, risk factors, and predictors of mortality.
Fraser, V. J., Jones, M., Dunkel, J., Storfer, S., Medoff, G., & Dunagan, W. C. (1992) · Clinical Infectious Diseases · doi:10.1093/clind/15.3.414 · Cited by 679 · see citing works
Early versus late necrosectomy in severe necrotizing pancreatitis
Mier, J., León, E. L.-D., Castillo, A., Robledo, F., & Blanco, R. (1997) · The American Journal of Surgery · doi:10.1016/s0002-9610(96)00425-4 · Cited by 539 · see citing works
Fluconazole prophylaxis prevents intra-abdominal candidiasis in high-risk surgical patients
Eggimann, P., Francioli, P., Bille, J., Schneider, R., Wu, M.-M., Chapuis, G., Chiolero, R., Pannatier, A., Schilling, J., Geroulanos, S., et al. (1999) · Critical Care Medicine · doi:10.1097/00003246-199906000-00019 · Cited by 414 · see citing works
Risk Factors for Hospital-Acquired Candidemia: A Matched Case-Control Study
Wey, S. B. (1989) · Archives of Internal Medicine · doi:10.1001/archinte.1989.00390100145030 · Cited by 369 · see citing works
Pelz, R. K., Hendrix, C. W., Swoboda, S. M., Diener‐West, M., Merz, W. G., Hammond, J., & Lipsett, P. A. (2001) · Annals of Surgery · doi:10.1097/00000658-200104000-00010 · Cited by 314 · see citing works
Winston, D. J., Pakrasi, A., & Busuttil, R. W. (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-131-10-199911160-00003 · Cited by 261 · see citing works
Garbino, J., Lew, D. P., Romand, J.-A., Hugonnet, S., Auckenthaler, R., & Pittet, D. (2002) · Intensive Care Medicine · doi:10.1007/s00134-002-1540-y · Cited by 247 · see citing works
Effects of nosocomial candidemia on outcomes of critically ill patients
Blot, S. I., Vandewoude, K. H., Hoste, E. A., & Colardyn, F. A. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(02)01248-2 · Cited by 235 · see citing works
Self-citationSandven, P., Qvist, H., Skovlund, E., & Giercksky, K. E. (2002) · Critical Care Medicine · doi:10.1097/00003246-200203000-00008 · Cited by 201 · see citing works
Pancreatic Infection in Severe Pancreatitis
Gloor, B. (2001) · Archives of Surgery · doi:10.1001/archsurg.136.5.592 · Cited by 191 · see citing works
Characteristics of Infection with Candida Species inPatients with Necrotizing Pancreatitis
Isenmann, R., Schwarz, M., Rau, B., Trautmann, M., Schober, W., & Beger, H. G. (2002) · World Journal of Surgery · doi:10.1007/s00268-001-0146-9 · Cited by 133 · see citing works
Fungal infection in acute necrotizing pancreatitis11No competing interests declared.
Grewe, M., Tsiotos, G. G., de-Leon, E. L., & Sarr, M. G. (1999) · Journal of the American College of Surgeons · doi:10.1016/s1072-7515(98)00334-2 · Cited by 116 · see citing works
Hoerauf, A. M., Hammer, S., Müller‐Myhsok, B., & Rupprecht, H. (1998) · Critical Care Medicine · doi:10.1097/00003246-199812000-00031 · Cited by 108 · see citing works
Fungal infection in the intensive care unit
Flanagan, P., & Barnes, R. A. (1998) · Journal of Hospital Infection · doi:10.1016/s0195-6701(98)90271-7 · Cited by 59 · see citing works
Safran, D. B. (1997) · Archives of Surgery · doi:10.1001/archsurg.1997.01430350034006 · Cited by 46 · see citing works
Fungal Infection in the Intensive Care Unit
Barnes, R., & Warnock, D. W. (2002) · Perspectives on critical care infectious diseases · doi:10.1007/978-1-4615-0977-6 · Cited by 11 · see citing works
Flagged first, then by citations
1 of the 20 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Grewe M, Tsiotos GG, Luque de-Leon E, et al. Fungal infection in acute necrotizing pancreatitis. J Am Coll Surg 1999; 188:408-14.
Cited by
Sorted by citations
Practice guidelines in acute pancreatitis
Banks, P. A., Freeman, M. L., & the Practice Parameters Committee of the American College of Gastroenterology (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00856.x · Cited by 2,050 · see citing works
Invasive fungal infections: a review of epidemiology and management options
Enoch, D., LUDLAM, H. A., & Brown, N. M. (2006) · Journal of Medical Microbiology · doi:10.1099/jmm.0.46548-0 · Cited by 503 · see citing works
Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
Villatoro, E. A., Mulla, M. G., & Larvin, M. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002941.pub3 · Cited by 422 · see citing works
Japanese guidelines for the management of acute pancreatitis: Japanese Guidelines 2015
Yokoe, M., Takada, T., Mayumi, T., Yoshida, M., Isaji, S., Wada, K., Itoi, T., Sata, N., Gabata, T., Igarashi, H., et al. (2015) · Journal of Hepato-Biliary-Pancreatic Sciences · doi:10.1002/jhbp.259 · Cited by 416 · see citing works
Management of the critically ill patient with severe acute pancreatitis
Nathens, A. B., Curtis, J. R., Beale, R. J., Cook, D. J., Moreno, R. P., Romand, J.-A., Skerrett, S. J., Stapleton, R. D., Ware, L. B., & Waldmann, C. S. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000148222.09869.92 · Cited by 351 · see citing works
Evidence-Based Treatment of Acute Pancreatitis
Heinrich, S., fer, M. S., Rousson, V., & Clavien, P. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000197334.58374.70 · Cited by 330 · see citing works
Timing of Surgical Intervention in Necrotizing Pancreatitis
Besselink, M. G. (2007) · Archives of Surgery · doi:10.1001/archsurg.142.12.1194 · Cited by 329 · see citing works
Invasive candidiasis in the intensive care unit
Ostrosky-Zeichner, L., & Pappas, P. G. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000201897.78123.44 · Cited by 247 · see citing works
ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients
Martín‐Loeches, I., Antonelli, M. M., Cuenca‐Estrella, M., Dimοpoulos, G., Einav, S., Waele, J. J. D., Garnacho‐Montero, J., Kanj, S. S., Machado, F. R., Montravers, P., et al. (2019) · Intensive Care Medicine · doi:10.1007/s00134-019-05599-w · Cited by 234 · see citing works
Critical Issues in the Clinical Management of Complicated Intra-Abdominal Infections
Blot, S. I., & Waele, J. J. D. (2005) · Drugs · doi:10.2165/00003495-200565120-00002 · Cited by 176 · see citing works
Self-citationInvasive Fungal Infections in the ICU: How to Approach, How to Treat
Paramythiotou, E., Frantzeskaki, F. G., Flevari, A., Armaganidis, A., & Dimοpoulos, G. (2014) · Molecules · doi:10.3390/molecules19011085 · Cited by 177 · see citing works
Guery, B. P., Arendrup, M. C., Auzinger, G., Azoulay, É., Borges Sá, M., Johnson, E. M., Müller, E., Putensen, C., Rotstein, C., Sganga, G., et al. (2009) · Intensive Care Medicine · doi:10.1007/s00134-008-1338-7 · Cited by 173 · see citing works
Meta-analysis of prophylactic antibiotic use in acute necrotizing pancreatitis
Mazaki, T., Ishii, Y., & Takayama, T. (2006) · British journal of surgery · doi:10.1002/bjs.5389 · Cited by 140 · see citing works
van Minnen, L. P., Timmerman, H. M., Lutgendorff, F., Verheem, A., Amerongen, W. C. M. H.-V., Konstantinov, S. R., Smidt, H., Visser, M. R., Rijkers, G. T., Gooszen, H. G., et al. (2007) · Surgery · doi:10.1016/j.surg.2006.10.007 · Cited by 126 · see citing works
Risk factors for albicans and non-albicans candidemia in the intensive care unit*
Chow, J. K., Golan, Y., Ruthazer, R., Karchmer, A. W., Carmeli, Y., Lichtenberg, D. A., Chawla, V., Young, J. A., & Hadley, S. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e31816fc4cd · Cited by 154 · see citing works
JPN Guidelines for the management of acute pancreatitis: medical management of acute pancreatitis
Takeda, K., Takada, T., Kawarada, Y., Hirata, K., Mayumi, T., Yoshida, M., Sekimoto, M., Hirota, M., Kimura, Y., Isaji, S., et al. (2006) · Journal of Hepato-Biliary-Pancreatic Surgery · doi:10.1007/s00534-005-1050-8 · Cited by 114 · see citing works
Acute pancreatitis at the beginning of the 21st century: The state of the art
Tonsi, A., Bacchion, M., Crippa, S., Malleo, G., & Bassi, C. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.2945 · Cited by 103 · see citing works
Current management of acute pancreatitis
Mayerle, J. V., Hlouschek, V., & Lerch, M. M. (2005) · Nature Clinical Practice Gastroenterology & Hepatology · doi:10.1038/ncpgasthep0293 · Cited by 103 · see citing works
Blot, S. I., Vandewoude, K. H., & Waele, J. J. D. (2007) · Current Opinion in Critical Care · doi:10.1097/mcc.0b013e328028fd92 · Cited by 93 · see citing works
Self-citationRecent Developments in Acute Pancreatitis
Talukdar, R., & Vege, S. S. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.07.037 · Cited by 92 · see citing works
Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
Villatoro, E. A., Bassi, C., & Larvin, M. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002941.pub2 · Cited by 90 · see citing works
New approaches to the risk of Candida in the intensive care unit
Ostrosky‐Zeichner, L. (2003) · Current Opinion in Infectious Diseases · doi:10.1097/00001432-200312000-00004 · Cited by 86 · see citing works
Role of Antibiotic Prophylaxis in Necrotizing Pancreatitis: A Meta-Analysis
Lim, C. L. L., Lee, W., Liew, Y. X., Tang, S. S. L., Chlebicki, M. P., & Kwa, A. L. (2015) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-014-2662-6 · Cited by 85 · see citing works
Management of Invasive Candidiasis in Critically Ill Patients
Blot, S. I., & Vandewoude, K. (2004) · Drugs · doi:10.2165/00003495-200464190-00002 · Cited by 80 · see citing works
Self-citationSepsis: From Pathophysiology to Individualized Patient Care
László, I., Trásy, D., Molnár, Z., & Fazakas, J. (2015) · Journal of Immunology Research · doi:10.1155/2015/510436 · Cited by 83 · see citing works
Caspofungin for prevention of intra-abdominal candidiasis in high-risk surgical patients
Senn, L., Eggimann, P., Ksontini, R., Pascual, A., Demartines, N., Billé, J., Calandra, T., & Marchetti, O. (2009) · Intensive Care Medicine · doi:10.1007/s00134-009-1405-8 · Cited by 80 · see citing works
Procalcitonin levels in surgical patients at risk of candidemia
Martini, A., Gottin, L., Menestrina, N., Schweiger, V., Simion, D., & Vincent, J. (2010) · Journal of Infection · doi:10.1016/j.jinf.2010.03.003 · Cited by 74 · see citing works
Imaging and Percutaneous Management of Acute Complicated Pancreatitis
Shankar, S., VANSONNENBERG, E., Silverman, S. G., Tuncali, K., & Banks, P. A. (2004) · CardioVascular and Interventional Radiology · doi:10.1007/s00270-004-0037-1 · Cited by 69 · see citing works
Intra-Abdominal Fungal Infections Complicating Acute Pancreatitis: A Review
Trikudanathan, G., Navaneethan, U., & Vege, S. S. (2011) · The American Journal of Gastroenterology · doi:10.1038/ajg.2010.497 · Cited by 70 · see citing works
Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults
Bow, E. J., Evans, G. A., Fuller, J., Laverdière, M., Rotstein, C., Rennie, R. P., Shafran, S. D., Sheppard, D. C., Carle, S., Phillips, P., et al. (2010) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2010/357076 · Cited by 68 · see citing works
Evidence-Based Treatment of Acute Pancreatitis: Antibiotic Prophylaxis in Necrotizing Pancreatitis
Besselink, M. G., van Santvoort, H. C., Buskens, E., & Gooszen, H. G. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000239627.78772.f7 · Cited by 68 · see citing works
Management of infected pancreatic necrosis in the intensive care unit: a narrative review
Wolbrink, D. R. J., Kolwijck, E., ten Oever, J., Horvath, K. D., Bouwense, S. A. W., & Schouten, J. A. (2019) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2019.06.017 · Cited by 67 · see citing works
Fundamental and intensive care of acute pancreatitis
Hirota, M., Takada, T., Kitamura, N., Ito, T., Hirata, K., Yoshida, M., Mayumi, T., Kataoka, K., Takeda, K., Sekimoto, M., et al. (2009) · Journal of Hepato-Biliary-Pancreatic Sciences · doi:10.1007/s00534-009-0210-7 · Cited by 61 · see citing works
Current diagnostic approaches to invasive candidiasis in critical care settings
Pemán, J., & Zaragoza, R. (2009) · Mycoses · doi:10.1111/j.1439-0507.2009.01732.x · Cited by 59 · see citing works
Antibiotic prophylaxis in severe acute pancreatitis
Beger, H. G., Rau, B., Isenmann, R., Schwarz, M., Gansauge, F., & Poch, B. (2005) · Pancreatology · doi:10.1159/000084485 · Cited by 59 · see citing works
Bench-to-bedside review: Therapeutic management of invasive candidiasis in the intensive care unit
Bassetti, M., Mikulska, M., & Viscoli, C. (2010) · Critical Care · doi:10.1186/cc9239 · Cited by 57 · see citing works
Candiduria in intensive care units: association with heavy colonization and candidaemia
Toya, S. P., Schraufnagel, D. E., & Tzelepis, G. E. (2007) · Journal of Hospital Infection · doi:10.1016/j.jhin.2007.03.028 · Cited by 57 · see citing works
Invasive Fungal Infections in the ICU
Shoham, S., & Marwaha, S. (2009) · Journal of Intensive Care Medicine · doi:10.1177/0885066609355262 · Cited by 53 · see citing works
Treatment strategy for acute pancreatitis
Wada, K., Takada, T., Hirata, K., Mayumi, T., Yoshida, M., Yokoe, M., Kiriyama, S., Hirota, M., Kimura, Y., Takeda, K., et al. (2009) · Journal of Hepato-Biliary-Pancreatic Sciences · doi:10.1007/s00534-009-0218-z · Cited by 54 · see citing works
Connor, S. J., Alexakis, N., Neal, T. J., Raraty, M. G. T., Ghaneh, P., Evans, J. C., Hughes, M., Rowlands, P. C., Garvey, C. J., Sutton, R., et al. (2004) · Digestive Surgery · doi:10.1159/000080884 · Cited by 51 · see citing works
Surgical critical care: Fungal infections in surgical patients
Lipsett, P. A. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000231883.93001.e0 · Cited by 51 · see citing works
Prevalence and outcome of fungal infection in patients with severe acute pancreatitis
Kochhar, R. K., Ahammed, S. K. M., Chakrabarti, A., Ray, P., Sinha, S. K., Dutta, U., Wig, J. D., & Singh, K. (2009) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2008.05712.x · Cited by 49 · see citing works
Emergence of Antibiotic Resistance in Infected Pancreatic Necrosis
Waele, J. J. D. (2004) · Archives of Surgery · doi:10.1001/archsurg.139.12.1371 · Cited by 49 · see citing works
Impact of Antibiotic-Resistant Bacterial and Fungal Infections in Outcome of Acute Pancreatitis
Moka, P., Goswami, P., Kapil, A., Xess, I., Sreenivas, V., & Saraya, A. (2018) · Pancreas · doi:10.1097/mpa.0000000000001019 · Cited by 47 · see citing works
EARLY DETECTION OF SYSTEMIC INFECTIONS
Blot, S. I., & Vandewoude, K. (2004) · Acta Clinica Belgica · doi:10.1179/acb.2004.003 · Cited by 47 · see citing works
Self-citationIs Candida really a threat in the ICU?
Blot, S. I., Dimopoulos, G., Rello, J., & Vogelaers, D. (2008) · Current Opinion in Critical Care · doi:10.1097/mcc.0b013e32830f1dff · Cited by 46 · see citing works
Self-citationThe use of prophylactic fluconazole in immunocompetent high-risk surgical patients: a meta-analysis
Ho, K. M., Lipman, J., DOBB, G. J., & Webb, S. A. R. (2005) · Critical Care · doi:10.1186/cc3883 · Cited by 43 · see citing works
Prediction of invasive candidal infection in critically ill patients with severeacute pancreatitis
Hall, A., Poole, L., Renton, B., Wozniak, A., Fisher, M., Neal, T. J., Halloran, C. M., Cox, T. F., & Hampshire, P. A. (2013) · Critical Care · doi:10.1186/cc12569 · Cited by 41 · see citing works
Necrotizing Pancreatitis: New Definitions and a New Era in Surgical Management
Rosenberg, A. L., Steensma, E. A., & Napolitano, L. M. (2015) · Surgical Infections · doi:10.1089/sur.2014.123 · Cited by 40 · see citing works
Zaragoza, R., Perman, J., Salavert, M., Viudes, Solé, A., Jarque, I., Cantón, R., Monte‐Boquet, E., & Romá, E. (2008) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s3994 · Cited by 40 · see citing works
Prevalence of Primary Fungal Infections in Necrotizing Pancreatitis
Berzin, T. M., Rocha, F. G., Whang, E. E., Mortelé, K. J., Ashley, S. W., & Banks, P. A. (2007) · Pancreatology · doi:10.1159/000101879 · Cited by 38 · see citing works
Outcomes of Intra-Abdominal Fungal vs. Bacterial Infections in Severe Acute Pancreatitis
Vege, S. S., Gardner, T. B., Chari, S. T., Baron, T. H., Clain, J. E., Pearson, R. K., Petersen, B. T., Farnell, M. B., & Sarr, M. G. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2009.280 · Cited by 39 · see citing works
Pancreatic Fungal Infection in Patients With Necrotizing Pancreatitis
Singh, R., Mitchell, W., David, Y. N., Cheesman, A. R., Dixon, R. E., Nagula, S., DiMaio, C. J., Greenwald, D. A., & Kumta, N. A. (2020) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000001467 · Cited by 37 · see citing works
ICU management of severe acute pancreatitis
Wilmer, A. P. (2004) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2004.06.004 · Cited by 37 · see citing works
Lionakis, M. S., Samonis, G., & Kontoyiannis, D. P. (2008) · Mayo Clinic Proceedings · doi:10.4065/83.9.1046 · Cited by 37 · see citing works
Prophylactic antibiotic use in severe acute pancreatitis: hemlock, help, or hype?
Brown, A. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.02.027 · Cited by 37 · see citing works
Fungal infections in severe acute pancreatitis
Kochhar, R. K., Noor, M. T., & Wig, J. D. (2011) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.06685.x · Cited by 36 · see citing works
Pharmacological Prevention and Treatment of Acute Pancreatitis: Where Are We Now?
Lankisch, P. G., & Lerch, M. M. (2006) · Digestive Diseases · doi:10.1159/000090318 · Cited by 33 · see citing works
Rational Use of Antimicrobials in Patients with Severe Acute Pancreatitis
Waele, J. J. D. (2011) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0031-1275529 · Cited by 34 · see citing works
Recomendaciones del Club Español Biliopancreático para el Tratamiento de la Pancreatitis Aguda
Navarro, S., Amador, J., Argüello, L., Ayuso, C., Boadas, J., Heras, G. D. L., Farré, A., Fernández‐Cruz, L., Ginés, À., Guarner, L., et al. (2008) · Gastroenterología y Hepatología · doi:10.1157/13123605 · Cited by 31 · see citing works
Chakrabarti, A., Rao, P., Tarai, B., Rudramurthy, S. M., & Wig, J. D. (2007) · Surgery Today · doi:10.1007/s00595-006-3371-x · Cited by 32 · see citing works
INVASIVE CANDIDIASIS IN NON-HEMATOLOGICAL PATIENTS.
Mikulska, M., Bassetti, M., Ratto, S., & Viscoli, C. (2011) · Mediterranean Journal of Hematology and Infectious Diseases · doi:10.4084/mjhid.2011.007 · Cited by 32 · see citing works
Medical treatment of acute pancreatitis
Mayerle, J. V., Simon, P., & Lerch, M. M. (2004) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2004.07.012 · Cited by 31 · see citing works
The Microbiology of Secondary and Postoperative Pancreatic Infections
Behrman, S. W. (2011) · Archives of Surgery · doi:10.1001/archsurg.2011.85 · Cited by 29 · see citing works
Microbiological Findings in Secondary Infection of Severe Acute Pancreatitis
Tsui, N.-C., Zhao, E., Li, Z., Miao, B., Cui, Y., Shen, Y., & Qu, P. (2009) · Pancreas · doi:10.1097/mpa.0b013e3181a16d12 · Cited by 29 · see citing works
The microbiology of infected pancreatic necrosis in the era of minimally invasive therapy
Sahar, N., Kozarek, R. A., Kanji, Z. S., Chihara, S., Gan, S. I., Irani, S. S., Larsen, M. C., Ross, A. S., & Glück, M. (2018) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-018-3259-x · Cited by 28 · see citing works
Vilar, S., Harpaz, R., Santana, L., Uriarte, E., & Friedman, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041471 · Cited by 27 · see citing works
van Till, J. W. O., van Ruler, O., Lamme, B., Weber, R. J., Reitsma, J. B., & Boermeester, M. A. (2007) · Critical Care · doi:10.1186/cc6191 · Cited by 24 · see citing works
Aparna, D., Kumar, S., & Kamalkumar, S. (2017) · World Journal of Gastrointestinal Surgery · doi:10.4240/wjgs.v9.i10.200 · Cited by 25 · see citing works
Waele, J. J. D., Rello, J., Anzueto, A., Moreno, R. P., Lipman, J., Sakr, Y. L., Pickkers, P., Léone, M., Ferguson, A. J., Oud, L., et al. (2014) · Surgical Infections · doi:10.1089/sur.2012.228 · Cited by 25 · see citing works
Epidemiología de las candidiasis invasoras en población pediátrica y adulta
del Palacio, A., Villar, J., & Alhambra, A. (2009) · Revista Iberoamericana de Micología · doi:10.1016/s1130-1406(09)70002-6 · Cited by 24 · see citing works
INFECTIOUS COMPLICATIONS OF ACUTE PANCREATITIS
Waele, J. J. D., Vogelaers, D., Decruyenaere, J. M. A., Vos, M. D., & COLARDYN, F. A. (2004) · Acta Clinica Belgica · doi:10.1179/acb.2004.013 · Cited by 25 · see citing works
Self-citationMicafungin Concentrations from Brain Tissue and Pancreatic Pseudocyst Fluid
Lat, A., Thompson, G. R., Rinaldi, M. G., Dorsey, S. A., Pennick, G. J., & Lewis, J. S. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01294-09 · Cited by 24 · see citing works
Horibe, M., Sanui, M., Sasaki, M., Honda, H., Ogura, Y., Namiki, S., Sawano, H., Goto, T., Ikeura, T., Takeda, T., et al. (2019) · Pancreas · doi:10.1097/mpa.0000000000001269 · Cited by 24 · see citing works
Evolving role of early antifungals in the adult intensive care unit
Lam, S. W., Eschenauer, G. A., & Carver, P. L. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e31819dec9b · Cited by 23 · see citing works
Fritz, S., Hartwig, W., Lehmann, R., Will-Schweiger, K., Kommerell, M., Hackert, T., Schneider, L., Büchler, M. W., & Werner, J. (2008) · Critical Care · doi:10.1186/cc7118 · Cited by 23 · see citing works
Laterre, P., COLARDYN, F. A., Delmée, M., Waele, J. J. D., Legrand, J.-C., Eldere, J. V., Vergison, A., & Vogelaer, D. (2006) · Acta chirurgica Belgica · doi:10.1080/00015458.2006.11679825 · Cited by 22 · see citing works
Self-citationCandidemia after cardiac surgery in the intensive care unit: an observational study
Pasero, D., Rosa, F. G. D., Rana, N. K., Fossati, L., Davi, A., Rinaldi, M., Perri, G. D., & Ranieri, V. M. (2010) · Interactive Cardiovascular and Thoracic Surgery · doi:10.1510/icvts.2010.257931 · Cited by 21 · see citing works
Management of Severe Acute Pancreatitis
Doctor, N., Agarwal, P., & Gandhi, V. (2011) · Indian Journal of Surgery · doi:10.1007/s12262-011-0384-5 · Cited by 20 · see citing works
Fungal Infections in Patients With Walled-off Pancreatic Necrosis
Werge, M. P., Roug, S., Novovic, S., Schmidt, P. N., Hansen, E. F., & Knudsen, J. D. (2016) · Pancreas · doi:10.1097/mpa.0000000000000675 · Cited by 19 · see citing works
Eggimann, P., Jamdar, S., & Siriwardena, A. K. (2006) · Critical Care · doi:10.1186/cc5025 · Cited by 19 · see citing works
Questions about the use of antibiotics in acute pancreatitis.
Campos, T. D., Assef, J. C., & Rasslan, S. (2006) · World Journal of Emergency Surgery · doi:10.1186/1749-7922-1-20 · Cited by 17 · see citing works
Poma, E. M., Urra, I. J., Raxach, J. G., Olascoaga, F. Z., Pérez‐Mateo, M., Casas, J. D., González, J. C. M., de Lorenzo, A. G., Camps, V. L., Fernández‐Mondejar, E., et al. (2005) · Medicina Intensiva · doi:10.1016/s0210-5691(05)74245-5 · Cited by 16 · see citing works
Management of candidaemia and invasive candidiasis in critically ill patients
Chahoud, J., Kanafani, Z. A., & Kanj, S. S. (2013) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2013.04.008 · Cited by 15 · see citing works
Use of antibiotics in severe acute pancreatitis
Waele, J. J. D. (2010) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.10.3 · Cited by 15 · see citing works
The Role of Antibiotic Prophylaxis in the Treatment of Acute Pancreatitis
Lankisch, P. G., & Lerch, M. M. (2005) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000196407.53228.ad · Cited by 15 · see citing works
Vasiliadis, K., Papavasiliou, C., Nimer, A. A., Lamprou, N., & Makridis, C. (2013) · ISRN Surgery · doi:10.1155/2013/579435 · Cited by 13 · see citing works
Azim, A., Ahmed, A., Baronia, A. K., Marak, R. S. K., & Muzzafar, N. (2017) · EMJ Nephrology · doi:10.33590/emjnephrol/10310735 · Cited by 12 · see citing works
JSMM Clinical Practice Guidelines for Diagnosis and Treatment of Invasive Candidiasis
(2013) · Medical Mycology Journal · doi:10.3314/mmj.54.147 · Cited by 12 · see citing works
Antibiotic prophylaxis: An ongoing controversy in the treatment of severe acute pancreatitis
Werner, J., Hartwig, W., & Büchler, M. W. (2007) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520701355378 · Cited by 12 · see citing works
Pancreatic colonization of fungi in the development of severe acute pancreatitis
Otsuka, Y., Kamata, K., Minaga, K., Watanabe, T., & Kudo, M. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.940532 · Cited by 11 · see citing works
Pilzinfektion bei hämorrhagisch‐nekrotisierender Pankreatitis: Risikofaktoren, Inzidenz, Therapie
Kujath, P., Rosenfeldt, M. T., Esnaashari, H., Scheele, J., & Bouchard, R. (2005) · Mycoses · doi:10.1111/j.1439-0507.2005.01108.x · Cited by 11 · see citing works
Hsu, F.-C., Lin, P., Chi, C.-Y., Ho, M., Ho, C., & Wang, J.-H. (2009) · PubMed · Cited by 11 · see citing works
Diagnostik und Therapie der akuten Pankreatitis
Adler, G., & Woehrle, H. (2005) · Der Internist · doi:10.1007/s00108-004-1319-z · Cited by 11 · see citing works
Antibiotic prophylaxis in acute necrotizing pancreatitis: yes or no?
Pezzilli, R. (2004) · PubMed · Cited by 11 · see citing works
Zaragoza, R., Pemán, J., & Salavert, M. (2008) · Revista Iberoamericana de Micología · doi:10.1016/s1130-1406(08)70049-4 · Cited by 10 · see citing works
Kaskel, P., Wissing, Ballus, J., Bingold, T. M., Nocea, Krobot, Kumar, & Mavros, P. (2013) · Infection and Drug Resistance · doi:10.2147/idr.s38945 · Cited by 10 · see citing works
Poma, E. M., Urra, I. J., Arana, E., Macaya, L., Escuchuri-Aisa, J., Lozano, O., Rodrigo, A., & Sánchez, J. S. (2008) · Medicina Intensiva · doi:10.1016/s0210-5691(08)70911-2 · Cited by 10 · see citing works
Risk management in patients with severe acute pancreatitis.
Gerlach, H. (2004) · Critical Care · doi:10.1186/cc3007 · Cited by 10 · see citing works
Infectious complications of pancreatitis: Diagnosis and management
Mishra, G., & Pineau, B. C. (2004) · Current Gastroenterology Reports · doi:10.1007/s11894-004-0079-1 · Cited by 10 · see citing works
- Authors
- De Waele, J. J., Vogelaers, D., Blot, S., & Colardyn, F.
- Affiliations
- Ghent University Hospital (BE)
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-07-15
- Volume
- 37
- Issue
- 2
- Pages
- 208-213
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2120036443
- Cited by
- 156
- References
- 20
- Citations by year
- 2026: 4 · 2025: 2 · 2023: 6 · 2022: 3 · 2021: 2 · 2020: 3 · 2019: 6 · 2018: 3 · 2017: 3 · 2016: 2 · 2015: 6 · 2014: 4 · 2013: 7 · 2012: 2
- FWCI
- 8.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
- Keywords
- fungal infection, severe acute pancreatitis, infected pancreatic necrosis, Candida albicans, fluconazole, antifungal prophylaxis, preemptive antifungal therapy, risk factors, mortality, critically ill patients
- MeSH terms
- Acute Disease, Anti-Bacterial Agents, Antifungal Agents, Candida albicans, Female, Humans, Length of Stay, Male, Middle Aged, Mycoses, Pancreatitis, Fluconazole, Incidence, Survival Rate, Treatment Outcome, Chemoprevention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
