PBAT: tools for family-based association studies.
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PBAT can handle nuclear families with missing parental genotypes, extended pedigrees with missing genotypic information, analysis of single nucleotide polymorphisms (SNPs), haplotype analysis, quantitative traits, multivariate/longitudinal data and time to onset phenotypes.
“PBAT can handle nuclear families with missing parental genotypes, extended pedigrees with missing genotypic information, analysis of single nucleotide polymorphisms (SNPs), haplotype analysis, quantitative traits, multivariate/longitudinal data and time to onset phenotypes.”
From The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task (2009) · cites this paper as [66]
The PBAT software package provides a unique set of tools for complex family-based association analysis at a genome-wide level.
“The PBAT software package provides a unique set of tools for complex family-based association analysis at a genome-wide level [65], [66].”
From The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task (2009) · cites this paper as [66]
The data analysis can be adjusted for covariates and gene/environment interactions.
“The data analysis can be adjusted for covariates and gene/environment interactions.”
From The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task (2009) · cites this paper as [66]
Haplotype-based features include sliding windows and the reconstruction of the haplotypes of the probands.
“Haplotype-based features include sliding windows and the reconstruction of the haplotypes of the probands.”
From The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task (2009) · cites this paper as [66]
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- Authors
- Lange, C., DeMeo, D., Silverman, E. K., Weiss, S. T., & Laird, N. M.
- Affiliations
- Harvard University (US)
- Brigham and Women's Hospital (US)
- Corresponding author
- Lange, Christoph
- Venue
- The American Journal of Human Genetics
- Publisher
- Elsevier BV
- Published
- 2004-02
- Volume
- 74
- Issue
- 2
- Pages
- 367-369
- ISSN
- 0002-9297 (ISSN-L)
- PMC
- PMC1181934
- OpenAlex
- W1981132558
- Cited by
- 268
- References
- 18
- Citations by year
- 2026: 2 · 2025: 1 · 2023: 1 · 2021: 2 · 2020: 2 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 8 · 2015: 8 · 2014: 13 · 2013: 12 · 2012: 17
- FWCI
- 13.03
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- The American Journal of Human Genetics (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (n01hr016049-010)
- National Heart, Lung, and Blood Institute (P01 HL67664, T32 HL07427, N01 HR016049, P01HL067664, N01 HLC6795, N01HR16049, T32HL007427)
- National Institute of Mental Health (R01MH59532, R01MH059532)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Keywords
- study design planning, genotype-phenotype correlation, nuclear family, photodynamic therapy
- MeSH terms
- Humans, Software, Genetic Diseases, Inborn
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