The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Viral Upper Respiratory Tract Infection and Otitis Media Complication in Young Children
Open accessAbstract
BACKGROUND: The common cold or upper respiratory infection (URI) is highly prevalent among young children and often results in otitis media (OM). The incidence and characteristics of OM complicating URI due to specific viruses have not been well studied. METHODS: We performed a prospective, longitudinal cohort study of 294 healthy children (age range, 6 months to 3 years). Each child was observed for 1 year to assess the occurrence of URI, acute OM (AOM), and OM with effusion (OME) complicating URI due to specific viruses. RESULTS: We documented 1295 URI episodes (5.06 episodes per child-year) and 440 AOM episodes (1.72 episodes per child-year). Virus studies were performed for 864 URI episodes; 63% were virus positive. Rhinovirus and adenovirus were most frequently detected during URI. The overall incidence of OM that complicated URI was 61%, including a 37% incidence of AOM and a 24% incidence of OME. Young age was the most important predictor of AOM that complicated URI. AOM occurred in approximately one-half of children with URI due to adenovirus, respiratory syncytial virus, or coronavirus and in approximately one-third of those with URI due to influenza virus, parainfluenza virus, enterovirus, or rhinovirus. CONCLUSIONS: More than 60% of episodes of symptomatic URI among young children were complicated by AOM and/or OME. Young age and specific virus types were predictors of URI complicated by AOM. For young children, the strategy to prevent OM should involve prevention of viral URI. The strategy may be more effective if the priority is given to development of means to prevent URI associated with adenovirus and respiratory syncytial virus.
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Citations
Cites
Diagnosis and Management of Acute Otitis Media
Media, S. O. M. O. A. O. (2004) · Pediatrics · doi:10.1542/peds.113.5.1451 · Cited by 902
Viruses and bacteria in the etiology of the common cold
Mäkelä, M. J., Puhakka, T., Ruuskanen, O., Leinonen, M., Saikku, P., Kimpimäki, M., Blomqvist, S., Hyypiä, T., & Arstila, P. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.2.539-542.1998 · Cited by 768
The Diagnosis and Management of Acute Otitis Media
(2021) · Pediatric Clinical Practice Guidelines & Policies, 21st Ed · doi:10.1542/9781610025034-part01-the_diagnosis · Cited by 692
Hayden, F. G., Fritz, R., Lobo, M. C., Alvord, W., Strober, W., & Straus, S. E. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1355 · Cited by 677
Prevalence of Various Respiratory Viruses in the Middle Ear during Acute Otitis Media
Heikkinen, T., Thint, M., & Chonmaitree, T. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901283400402 · Cited by 524
Self-citationTrends in Antimicrobial Prescribing Rates for Children and Adolescents
McCaig, L. F. (2002) · JAMA · doi:10.1001/jama.287.23.3096 · Cited by 517
Henderson, F. W., Collier, A. M., Sanyal, M. A., Watkins, J. M., Fairclough, D. L., Clyde, W. A., & Denny, F. W. (1982) · New England Journal of Medicine · doi:10.1056/nejm198206103062301 · Cited by 393
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Kesebir, D., Vazquez, M., Weibel, C., Shapiro, E. D., Ferguson, D., Landry, M. L., & Kahn, J. S. (2006) · The Journal of Infectious Diseases · doi:10.1086/508213 · Cited by 336
Acute Respiratory Illness in an American Community: The Tecumseh Study
Monto, A. S. (1974) · JAMA · doi:10.1001/jama.1974.03230150016004 · Cited by 297 · cited 1×
“The limit of detection for coronavirus 2 1 ϫ 10 OC43/229E (N gene) and NL63 (N gene) were 10 Ϫ2 TCID 50 / mL and 10 Ϫ1 TCID 50 /mL, respectively; for rhinovirus (5 NTR gene), it was 10 Ϫ2 TCID 50 /mL; and for enterovirus (5 NTR), it was 10 Ϫ2 TCID 50 /mL.”
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Cited by
The Diagnosis and Management of Acute Otitis Media
Lieberthal, A. S., Carroll, A. E., Chonmaitree, T., Ganiats, T. G., Hoberman, A., Jackson, M. A., Joffe, M. D., Miller, D. T., Rosenfeld, R. M., Sevilla, X. D., et al. (2013) · Pediatrics · doi:10.1542/peds.2012-3488 · Cited by 1,442
Self-citationRespiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology
Tregoning, J. S., & Schwarze, J. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00032-09 · Cited by 747
Microbial Communities of the Upper Respiratory Tract and Otitis Media in Children
Laufer, A. S., Metlay, J. P., Gent, J. F., Fennie, K. P., Kong, Y., & Pettigrew, M. M. (2011) · mBio · doi:10.1128/mbio.00245-10 · Cited by 224
“No significant associations were found, perhaps because all study subjects presented with upper respiratory tract infection, a major OM risk factor (8).”
BackgroundVu, H. T. T., Yoshida, L. M., Suzuki, M., Nguyen, H. A. T., Nguyen, C. D. L., Nguyen, A. T. T., Oishi, K., Yamamoto, T., Watanabe, K., Vu, T. D., et al. (2011) · Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181f111a2 · Cited by 208
Pettigrew, M. M., Laufer, A. S., Gent, J. F., Kong, Y., Fennie, K. P., & Metlay, J. P. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.01051-12 · Cited by 183
Metadata
- Authors
- Chonmaitree, T., Revai, K., Grady, J. J., Clos, A., Patel, J. A., Nair, S., Fan, J., & Henrickson, K. J.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-03-15
- Volume
- 46
- Issue
- 6
- Pages
- 815-823
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2110661096
- Cited by
- 435
- References
- 37
- FWCI
- 24.28
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Chonmaitree, T., Revai, K., Grady, J. J., Clos, A., Patel, J. A., Nair, S., Fan, J., & Henrickson, K. J. (2008). Viral Upper Respiratory Tract Infection and Otitis Media Complication in Young Children. Clinical Infectious Diseases. https://doi.org/10.1086/528685
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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