The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Diagnosis and Management of Acute Otitis Media
Abstract
This evidence-based clinical practice guideline provides recommendations to primary care clinicians for the management of children from 2 months through 12 years of age with uncomplicated acute otitis media (AOM). The American Academy of Pediatrics and American Academy of Family Physicians convened a committee composed of primary care physicians and experts in the fields of otolaryngology, epidemiology, and infectious disease. The subcommittee partnered with the Agency for Healthcare Research and Quality and the Southern California Evidence-Based Practice Center to develop a comprehensive review of the evidence-based literature related to AOM. The resulting evidence report and other sources of data were used to formulate the practice guideline recommendations. The focus of this practice guideline is the appropriate diagnosis and initial treatment of a child presenting with AOM. The guideline provides a specific definition of AOM. It addresses pain management, initial observation versus antibacterial treatment, appropriate choices of antibacterials, and preventive measures. Decisions were made based on a systematic grading of the quality of evidence and strength of recommendations, as well as expert consensus when definitive data were not available. The practice guideline underwent comprehensive peer review before formal approval by the partnering organizations. This clinical practice guideline is not intended as a sole source of guidance in the management of children with AOM. Rather, it is intended to assist primary care clinicians by providing a framework for clinical decision-making. It is not intended to replace clinical judgment or establish a protocol for all children with this condition. These recommendations may not provide the only appropriate approach to the management of this problem.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Unconventional medicine in the United States-Prevalence, costs, and patterns of use
Eisenberg, D. M., Kessler, R. C., Foster, C., Norlock, F. E., Calkins, D. R., & Delbanco, T. L. (1993) · New England Journal of Medicine · doi:10.1056/nejm199301283280406 · Cited by 4,177 · cited 1×
“) Increasing numbers of parents and caregivers are using various forms of nonconventional treatment for their children.(128,129) The types of treatments used can differ depending on the ethnic background and belief system of the family and the availability of alternative medicine in a particular community.”
Research works printed but not linked: 131
- Schappert SM. Office visits for otitis media: United States, 1975–90. Adv Data. 1992;214:1–18
- Cherry DK, Woodwell DA. National ambulatory medical care survey: 2000 summary. Adv Data. 2002;328:1–32
- McCaig LF, Besser RE, Hughes JM. Trends in antimicrobial prescribing rates for children and adolescents. JAMA. 2002;287:3096–3102 · DOI · Paper page
- Niemela M, Uhari M, Jounio-Ervasti K, Luotonen J, Alho OP, Vierimaa E. Lack of specific symptomatology in children with acute otitis media. Pediatr Infect Dis J. 1994;13:765–768 · DOI
- Kontiokari T, Koivunen P, Niemela M, Pokka T, Uhari M. Symptoms of acute otitis media. Pediatr Infect Dis J. 1998;17:676–679 · DOI
- Pelton SI. Otoscopy for the diagnosis of otitis media. Pediatr Infect Dis J. 1998;17:540–543 · doi:10.1097/00006454-199806000-00032
- Brookhouser PE. Use of tympanometry in office practice for diagnosis of otitis media. Pediatr Infect Dis J. 1998;17:544–551 · DOI
- Kimball S. Acoustic reflectometry: spectral gradient analysis for improved detection of middle ear effusion in children. Pediatr Infect Dis J. 1998;17:552–555 · doi:10.1097/00006454-199806000-00034
- Barnett ED, Klein JO, Hawkins KA, Cabral HJ, Kenna M, Healy G. Comparison of spectral gradient acoustic reflectometry and other diagnostic techniques for detection of middle ear effusion in children with middle ear disease. Pediatr Infect Dis J. 1998;17:556–559 · doi:10.1097/00006454-199806000-00035
- Block SL, Mandel E, McLinn S, et al. Spectral gradient acoustic reflectometry for detection of middle ear effusion by pediatricians and parents. Pediatr Infect Dis J. 1998;17:560–564 · doi:10.1097/00006454-199806000-00036
- Block SL, Pichichero ME, McLinn S, Aronovitz G, Kimball S. Spectral gradient acoustic reflectometry: detection of middle ear effusion in suppurative acute otitis media. Pediatr Infect Dis J. 1999;18:741–744 · doi:10.1097/00006454-199908000-00024
- Karma PH, Penttila MA, Sipila MM, Kataja MJ. Otoscopic diagnosis of middle ear effusion in acute and non-acute otitis media. I. The value of different otoscopic findings. Int J Pediatr Otorhinolaryngol. 1989;17:37–49 · DOI · Paper page
- Karma PH, Sipila MM, Kataja MJ, Penttila MA. Pneumatic otoscopy and otitis media. II. Value of different tympanic membrane findings and their combinations. In: Lim DJ, Bluestone CD, Klein JO, Nelson JD, Ogra PL, eds. Recent Advances in Otitis Media: Proceedings of the Fifth International Symposium. Burlington, ON, Canada: Decker Periodicals; 1993:41–45
- Merifield DO, Miller GS. The etiology and clinical course of bullous myringitis. Arch Otolaryngol. 1966;84:487–489 · doi:10.1001/archotol.1966.00760030489004
- Klein JO, McCracken GH Jr. Introduction: current assessments of diagnosis and management of otitis media. Pediatr Infect Dis J. 1998;17:539
- Pichichero ME, Poole MD. Assessing diagnostic accuracy and tympanocentesis skills in the management of otitis media. Arch Pediatr Adolesc Med. 2001;155:1137–1142 · DOI · Paper page
- Pichichero ME. Diagnostic accuracy, tympanocentesis training performance, and antibiotic selection by pediatric residents in management of otitis media. Pediatrics. 2002;110:1064–1070 · DOI
- Chonmaitree T. Viral and bacterial interaction in acute otitis media. Pediatr Infect Dis J. 2000;19(suppl):S24–S30 · DOI
- Dowell SF, Marcy SM, Phillips WR, Gerber MA, Schwartz B. Otitis media—principles of judicious use of antimicrobial agents. Pediatrics. 1998;101:165–171 · DOI · Paper page
- Wald ER. Acute otitis media: more trouble with the evidence. Pediatr Infect Dis J. 2003;22:103–104 · DOI
- Rosenfeld RM. Diagnostic certainty for acute otitis media. Int J Pediatr Otorhinolaryngol. 2002;64:89–95 · doi:10.1016/s0165-5876(02)00073-3
- Hayden GF, Schwartz RH. Characteristics of earache among children with acute otitis media. Am J Dis Child. 1985;139:721–723 · DOI
- Schechter NL. Management of pain associated with acute medical illness. In: Schechter NL, Berde CB, Yaster M, eds. Pain in Infants, Children, and Adolescents. Baltimore, MD: Williams & Wilkins; 1993:537–538
- American Academy of Pediatrics, Committee on Psychosocial Aspects of Child and Family Health; Task Force on Pain in Infants, Children, and Adolescents. The assessment and management of acute pain in infants, children, and adolescents. Pediatrics. 2001;108:793–797 · DOI · Paper page
- Bertin L, Pons G, d'Athis P, et al. A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children. Fundam Clin Pharmacol. 1996;10:387–392 · DOI
- Hoberman A, Paradise JL, Reynolds EA, Urkin J. Efficacy of Auralgan for treating ear pain in children with acute otitis media. Arch Pediatr Adolesc Med. 1997;151:675–678 · DOI
- Sarrell EM, Mandelberg A, Cohen HA. Efficacy of naturopathic extracts in the management of ear pain associated with acute otitis media. Arch Pediatr Adolesc Med. 2001;155:796–799 · DOI
- Barnett ED, Levatin JL, Chapman EH, et al. Challenges of evaluating homeopathic treatment of acute otitis media. Pediatr Infect Dis J. 2000;19:273–275 · DOI
- Jacobs J, Springer DA, Crothers D. Homeopathic treatment of acute otitis media in children: a preliminary randomized placebo-controlled trial. Pediatr Infect Dis J. 2001;20:177–183 · DOI · Paper page
- Rosenfeld RM, Bluestone CD. Clinical efficacy of surgical therapy. In: Rosenfeld RM, Bluestone CD, eds. Evidence-Based Otitis Media. 2nd ed. Hamilton, ON, Canada: BC Decker Inc; 2003:227–240
- Rosenfeld RM. Observation option toolkit for acute otitis media. Int J Pediatr Otorhinolaryngol. 2001;58:1–8 · DOI
- Rosenfeld RM, Vertrees JE, Carr J, et al. Clinical efficacy of antimicrobial drugs for acute otitis media: metaanalysis of 5400 children from thirty-three randomized trials. J Pediatr. 1994;124:355–367 · DOI · Paper page
- Del Mar C, Glasziou P, Hayem M. Are antibiotics indicated as initial treatment for children with acute otitis media? A meta-analysis. BMJ. 1997;314:1526–1529 · DOI · Paper page
- Glasziou PP, Del Mar CB, Hayem M, Sanders SL. Antibiotics for acute otitis media in children. Cochrane Database Syst Rev. 2000;4:CD000219 · doi:10.1002/14651858.cd000219
- Rosenfeld RM, Kay D. Natural history of untreated otitis media. In: Rosenfeld RM, Bluestone CD, eds. Evidence-Based Otitis Media. 2nd ed. Hamilton, ON, Canada: BC Decker Inc; 2003:180–198
- Appelman CL, Van Balen FA, Van de Lisdonk EH, Van Weert HC, Eizenga WH. Otitis media acuta. NHG-standaard (eerste herziening) [in Dutch]. Huisarts Wet. 1999;42:362–366
- van Buchem FL, Peeters MF, van't Hof MA. Acute otitis media: a new treatment strategy. Br Med J (Clin Res Ed). 1985;290:1033–1037 · DOI
- Little P, Gould C, Williamson I, Moore M, Warner G, Dunleavey J. Pragmatic randomised controlled trial of two prescribing strategies for childhood acute otitis media. BMJ. 2001;322:336–342 · DOI · Paper page
- Little P, Gould C, Moore M, Warner G, Dunleavey J, Williamson I. Predictors of poor outcome and benefits from antibiotics in children with acute otitis media: pragmatic randomised trial. BMJ. 2002;325:22 · doi:10.1136/bmj.325.7354.22
- Kaleida PH, Casselbrant ML, Rockette HE, et al. Amoxicillin or myringotomy or both for acute otitis media: results of a randomized clinical trial. Pediatrics. 1991;87:466–474 · DOI · Paper page
- Barry B, Gehanno P, Blumen M, Boucot I. Clinical outcome of acute otitis media caused by pneumococci with decreased susceptibility to penicillin. Scand J Infect Dis. 1994;26:446–452 · doi:10.3109/00365549409008618
- Appelman CL, Claessen JQ, Touw-Otten FW, Hordijk GJ, de Melker RA. Co-amoxiclav in recurrent acute otitis media: placebo controlled study. BMJ. 1991;303:1450–1452 · DOI
- Froom J, Culpepper L, Grob P, et al. Diagnosis and antibiotic treatment of acute otitis media: report from International Primary Care Network. BMJ. 1990;300:582–586 · DOI · Paper page
- Froom J, Culpepper L, Bridges-Webb C, et al. Effect of patient characteristics and disease manifestations on the outcome of acute otitis media at 2 months. Arch Fam Med. 1993;2:841–846 · doi:10.1001/archfami.2.8.841
- Shurin PA, Rehmus JM, Johnson CE, et al. Bacterial polysaccharide immune globulin for prophylaxis of acute otitis media in high-risk children. J Pediatr. 1993;123:801–810 · DOI
- Rudberg RD. Acute otitis media: comparative therapeutic results of sulfonamide and penicillin administered in various forms. Acta Otolaryngol Suppl. 1954;113:1–79
- Palva T, Pulkkinen K. Mastoiditis. J Laryngol Otol. 1959;73:573–588 · doi:10.1017/s0022215100055742
- Hoppe JE, Koster S, Bootz F, Niethammer D. Acute mastoiditis—relevant once again. Infection. 1994;22:178–182 · doi:10.1007/bf01716698
- Bahadori RS, Schwartz RH, Ziai M. Acute mastoiditis in children: an increase in frequency in Northern Virginia. Pediatr Infect Dis J. 2000;19:212–215 · doi:10.1097/00006454-200003000-00007
- Faye-Lund H. Acute and latent mastoiditis. J Laryngol Otol. 1989;103:1158–1160 · doi:10.1017/s0022215100111260
- Ghaffar FA, Wordemann M, McCracken GH Jr. Acute mastoiditis in children: a seventeen-year experience in Dallas, Texas. Pediatr Infect Dis J. 2001;20:376–380 · doi:10.1097/00006454-200104000-00003
- Harley EH, Sdralis T, Berkowitz RG. Acute mastoiditis in children: a 12-year retrospective study. Otolaryngol Head Neck Surg. 1997;116:26–30 · doi:10.1016/s0194-5998(97)70347-4
- Kaplan SL, Mason EO Jr, Wald ER, et al. Pneumococcal mastoiditis in children. Pediatrics. 2000;106:695–699 · DOI
- Kvestad E, Kvaerner KJ, Mair IW. Acute mastoiditis: predictors for surgery. Int J Pediatr Otorhinolaryngol. 2000;52:149–155 · doi:10.1016/s0165-5876(00)00287-1
- Linder TE, Briner HR, Bischoff T. Prevention of acute mastoiditis: fact or fiction?Int J Pediatr Otorhinolaryngol. 2000;56:129–134 · doi:10.1016/s0165-5876(00)00410-9
- Nadal D, Herrmann P, Baumann A, Fanconi A. Acute mastoiditis: clinical, microbiological, and therapeutic aspects. Eur J Pediatr. 1990;149:560–564 · doi:10.1007/bf01957692
- Petersen CG, Ovesen T, Pedersen CB. Acute mastoidectomy in a Danish county from 1977 to 1996 with focus on the bacteriology. Int J Pediatr Otorhinolaryngol. 1998;45:21–29 · doi:10.1016/s0165-5876(98)00080-9
- Scott TA, Jackler RK. Acute mastoiditis in infancy: a sequela of unrecognized acute otitis media. Otolaryngol Head Neck Surg. 1989;101:683–687 · doi:10.1177/019459988910100611
- Dhooge IJ, Albers FW, Van Cauwenberge PB. Intratemporal and intracranial complications of acute suppurative otitis media in children: renewed interest. Int J Pediatr Otorhinolaryngol. 1999;49:S109–S114 · doi:10.1016/s0165-5876(99)00144-5
- Gliklich RE, Eavey RD, Iannuzzi RA, Camacho AE. A contemporary analysis of acute mastoiditis. Arch Otolaryngol Head Neck Surg. 1996;122:135–139 · doi:10.1001/archotol.1996.01890140023006
- Luntz M, Brodsky A, Nusem S, et al. Acute mastoiditis—the antibacterial agent era: a multicenter study. Int J Pediatr Otorhinolaryngol. 2001;57:1–9 · DOI · Paper page
- Van Zuijlen DA, Schilder AG, Van Balen FA, Hoes AW. National differences in acute mastoiditis: relationship to prescribing patterns of antibiotics for acute otitis media?Pediatr Infect Dis J. 2001;20:140–144 · DOI · Paper page
- Schutzman SA, Petrycki S, Fleisher GR. Bacteremia with otitis media. Pediatrics. 1991;87:48–53 · doi:10.1542/peds.87.1.48
- Damoiseaux RA, van Balen FA, Hoes AW, Vaerheij TJ, de Melker RA. Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. BMJ. 2000;320:350–354 · DOI
- Kilpi T, Anttila M, Kallio MJ, Peltola H. Severity of childhood bacterial meningitis: duration of illness before diagnosis. Lancet. 1991;338:406–409 · DOI
- Whitney CG, Farley MM, Hadler J, et al. Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. N Engl J Med. 2003;348:1737–1746 · DOI · Paper page
- Dagan R, McCracken GH Jr. Flaws in design and conduct of clinical trials in acute otitis media. Pediatr Infect Dis J. 2002;21:894–902 · DOI
- Cates C. An evidence based approach to reducing antibiotic use in children with acute otitis media: controlled before and after study. BMJ. 1999;318:715–716 · doi:10.1136/bmj.318.7185.715
- Siegel RM, Kiely M, Bien JP, et al. Treatment of otitis media with observation and a safety-net antibiotic prescription. Pediatrics. 2003;112:527–531 · DOI
- Rosenfeld RM. Clinical efficacy of medical therapy. In: Rosenfeld RM, Bluestone CD, eds. Evidence-Based Otitis Media. 2nd ed. Hamilton, ON, Canada: BC Decker Inc; 2003:199–226
- Burke P, Bain J, Robinson D, Dunleavey J. Acute red ear in children: controlled trial of non-antibiotic treatment in general practice. BMJ. 1991;303:558–562 · DOI · Paper page
- Ruben RJ. Sequelae of antibiotic therapy. In: Rosenfeld RM, Bluestone CD, eds. Evidence-Based Otitis Media. Hamilton, ON, Canada: BC Decker Inc; 1999:303–314
- Piglansky L, Leibovitz E, Raiz S, et al. Bacteriologic and clinical efficacy of high dose amoxicillin for therapy of acute otitis media in children. Pediatr Infect Dis J. 2003;22:405–413 · DOI
- Dagan R, Hoberman A, Johnson C, et al. Bacteriologic and clinical efficacy of high dose amoxicillin/clavulanate in children with acute otitis media. Pediatr Infect Dis J. 2001;20:829–837 · DOI
- Dagan R, Leibovitz E, Greenberg D, Yagupsky P, Fliss DM, Leiberman A. Early eradication of pathogens from middle ear fluid during antibiotic treatment of acute otitis media is associated with improved clinical outcome. Pediatr Infect Dis J. 1998;17:776–782 · DOI · Paper page
- Marchant CD, Carlin SA, Johnson CE, Shurin PA. Measuring the comparative efficacy of antibacterial agents for acute otitis media: the “Pollyanna phenomenon.” J Pediatr. 1992;120:72–77 · DOI · Paper page
- Carlin SA, Marchant CD, Shurin PA, Johnson CE, Super DM, Rehmus JM. Host factors and early therapeutic response in acute otitis media. J Pediatr. 1991;118:178–183 · DOI
- Vogelman B, Gudmundsson S, Leggett J, Turnidge J, Ebert S, Craig WA. Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model. J Infect Dis. 1988;158:831–847 · DOI · Paper page
- Craig W. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis. 1998;26:1–10 · DOI · Paper page
- Berman S. Otitis media in children. N Engl J Med. 1995;332:1560–1565 · DOI · Paper page
- Klein JO. Otitis media. Clin Infect Dis. 1994;19:823–833 · DOI · Paper page
- Pitkaranta A, Virolainen A, Jero J, Arruda E, Hayden FG. Detection of rhinovirus, respiratory syncytial virus, and coronavirus infections in acute otitis media by reverse transcriptase polymerase chain reaction. Pediatrics. 1998;102:291–295 · DOI · Paper page
- Heikkinen T, Thint M, Chonmaitree T. Prevalence of various respiratory viruses in the middle ear during acute otitis media. N Engl J Med. 1999;340:260–264 · DOI · Paper page
- Doern GV, Jones RN, Pfaller MA, Kugler K. Haemophilus influenzae and Moraxella catarrhalis from patients with community-acquired respiratory tract infections: antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (United States and Canada, 1997). Antimicrob Agents Chemother. 1999;43:385–389 · DOI · Paper page
- Sinus and Allergy Health Partnership. Antibacterial treatment guidelines for acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg. 2000;123:S5–S31 · DOI
- Doern GV, Brueggemann AB, Pierce G, Holley HP Jr, Rauch A. Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of beta-lactamase-positive strains resistant to amoxicillin-clavulanate: results of a national multicenter surveillance study. Antimicrob Agents Chemother. 1997;41:292–297 · doi:10.1128/aac.41.2.292
- Doern GV, Pfaller MA, Kugler K, Freeman J, Jones RN. Prevalence of antimicrobial resistance among respiratory tract isolates of Streptococcus pneumoniae in North America: 1997 results from the SENTRY Antimicrobial Surveillance Program. Clin Infect Dis. 1998;27:764–770 · DOI · Paper page
- Jacobs MR, Felmingham D, Appelbaum PC, Guneberg RN, Alexander Project Group. The Alexander Project 1998–2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents. J Antimicrob Chemother. 2003;52:229–246 · DOI · Paper page
- Howie VM, Ploussard JH. Efficacy of fixed combination antibiotics versus separate components in otitis media. Effectiveness of erythromycin estolate, triple sulfonamide, ampicillin, erythromycin estolate-triple sulfonamide, and placebo in 280 patients with acute otitis media under two and one-half years of age. Clin Pediatr (Phila). 1972;11:205–214 · DOI · Paper page
- Klein JO. Microbiologic efficacy of antibacterial drugs for acute otitis media. Pediatr Infect Dis J. 1993;12:973–975 · DOI
- Barnett ED, Klein JO. The problem of resistant bacteria for the management of acute otitis media. Pediatr Clin North Am. 1995;42:509–517 · DOI
- Jacobs MR, Bajaksouzian S, Zilles A, Lin G, Pankuch GA, Appelbaum PC. Susceptibilities of Streptococcus pneumoniae and Haemophilus influenzae to 10 oral antimicrobial agents, based on pharmacodynamic parameters: 1997 U.S. Surveillance study. Antimicrob Agents Chemother. 1999;43:1901–1908 · DOI · Paper page
- Wald ER, Mason EO Jr, Bradley JS, Barson WJ, Kaplan SL, US Pediatric Multicenter Pneumococcal Surveillance Group. Acute otitis media caused by Streptococcus pneumoniae in children's hospitals between 1994 and 1997. Pediatr Infect Dis J. 2001;20:34–39 · doi:10.1097/00006454-200101000-00007
- Kellner JD, Ford-Jones EL. Streptococcus pneumoniae carriage in children attending 59 Canadian child care centers. Toronto Child Care Centre Study Group. Arch Pediatr Adolesc Med. 1999;153:495–502 · DOI
- Green SM, Rothrock SG. Single-dose intramuscular ceftriaxone for acute otitis media in children. Pediatrics. 1993;91:23–30 · DOI
- Leibovitz E, Piglansky L, Raiz S, Press J, Leiberman A, Dagan R. Bacteriologic and clinical efficacy of one day vs. three day intramuscular ceftriaxone for treatment of nonresponsive acute otitis media in children. Pediatr Infect Dis J. 2000;19:1040–1045 · DOI
- Paradise JL. Short-course antibacterial treatment for acute otitis media: not best for infants and young children. JAMA. 1997;278:1640–1642 · doi:10.1001/jama.278.20.1640
- Hoberman A, Paradise JL, Burch DJ, et al. Equivalent efficacy and reduced occurrence of diarrhea from a new formulation of amoxicillin/clavulanate potassium (Augmentin) for treatment of acute otitis media in children. Pediatr Infect Dis J. 1997;16:463–470 · DOI
- Cohen R, Levy C, Boucherat M, Langue J, de la Rocque F. A multicenter, randomized, double-blind trial of 5 versus 10 days of antibacterial agent therapy for acute otitis media in young children. J Pediatr. 1998;133:634–639 · DOI
- Cohen R, Levy C, Boucherat M, et al. Five vs. ten days of antibiotic therapy for acute otitis media in young children. Pediatr Infect Dis J. 2000;19:458–463 · DOI
- Pessey JJ, Gehanno P, Thoroddsen E, et al. Short course therapy with cefuroxime axetil for acute otitis media: results of a randomized multicenter comparison with amoxicillin/clavulanate. Pediatr Infect Dis J. 1999;18:854–859 · DOI
- Pichichero ME, Marsocci SM, Murphy ML, Hoeger W, Francis AB, Green JL. A prospective observational study of 5-, 7-, and 10-day antibiotic treatment for acute otitis media. Otolaryngol Head Neck Surg. 2001;124:381–387 · DOI
- Dowell SF, Butler JC, Giebink SG, et al. Acute otitis media: management and surveillance in an era of pneumococcal resistance—a report from the Drug-Resistant Streptococcus pneumoniae Therapeutic Working Group. Pediatr Infect Dis J. 1999;18:1–9 · DOI · Paper page
- Leiberman A, Leibovitz E, Piglansky L, et al. Bacteriologic and clinical efficacy of trimethoprim-sulfamethoxazole for the treatment of acute otitis media. Pediatr Infect Dis J. 2001;20:260–264 · DOI
- Daly KA, Giebink GS. Clinical epidemiology of otitis media. Pediatr Infect Dis J. 2000;19(suppl 5):S31–S36 · DOI
- Paradise JL, Rockette HE, Colborn DK, et al. Otitis media in 2253 Pittsburgh-area infants: prevalence and risk factors during the first two years of life. Pediatrics. 1997;99:318–333 · DOI · Paper page
- Kero P, Piekkala P. Factors affecting the occurrence of acute otitis media during the first year of life. Acta Paediatr Scand. 1987;76:618–623 · DOI
- Curns AT, Holman RC, Shay DK, et al. Outpatient and hospital visits associated with otitis media among American Indian and Alaska Native children younger than 5 years. Pediatrics. 2002;109(3). Available at: www.pediatrics.org/cgi/content/full/109/3/e41 · DOI
- Casselbrant ML, Mandel EM, Fall PA, et al. The hereditability of otitis media: a twin and triplet study. JAMA. 1999;282:2125–2130 · DOI · Paper page
- Uhari M, Mantysaari K, Niemela M. A meta-analytic review of the risk factors for acute otitis media. Clin Infect Dis. 1996;22:1079–1083 · DOI · Paper page
- Adderson EE. Preventing otitis media: medical approaches. Pediatr Ann. 1998;27:101–107 · DOI
- Brown CE, Magnuson B. On the physics of the infant feeding bottle and middle ear sequela: ear disease in infants can be associated with bottle feeding. Int J Pediatr Otorhinolaryngol. 2000;54:13–20 · DOI
- Niemela M, Pihakari O, Pokka T, Uhari M. Pacifier as a risk factor for acute otitis media: a randomized, controlled trial of parental counseling. Pediatrics. 2000;106:483–488 · DOI
- Etzel RA, Pattishall EN, Haley NJ, Fletcher RH, Henderson FW. Passive smoking and middle ear effusion among children in day care. Pediatrics. 1992;90:228–232 · DOI
- Ilicali OC, Keles N, Deger K, Savas I. Relationship of passive cigarette smoking to otitis media. Arch Otolaryngol Head Neck Surg. 1999;125:758–762 · DOI
- Wellington M, Hall CB. Pacifier as a risk factor for acute otitis media [letter]. Pediatrics. 2002;109:351 · DOI
- Paradise JL, Ah-Tye C. Positional otitis media and otorrhea after tympanostomy-tube placement [letter]. Pediatrics. 2002;109:349–350 · doi:10.1542/peds.109.2.349
- Clements DA, Langdon L, Bland C, Walter E. Influenza A vaccine decreases the incidence of otitis media in 6- to 30-month-old children in day care. Arch Pediatr Adolesc Med. 1995;149:1113–1117 · DOI · Paper page
- Belshe RB, Gruber WC. Prevention of otitis media in children with live attenuated influenza vaccine given intranasally. Pediatr Infect Dis J. 2000;19(suppl 5):S66–S71 · DOI
- Hoberman A, Greenberg DP, Paradise JL, et al. Effectiveness of inactivated influenza vaccine in preventing acute otitis media in young children: a randomized controlled trial. JAMA. 2003;290:1608–1616 · DOI · Paper page
- Eskola J, Kilpi T, Palmu A, et al. Efficacy of a pneumococcal conjugate vaccine against acute otitis media. N Engl J Med. 2001;344:403–409 · DOI · Paper page
- Black S, Shinefield H, Fireman B, et al. Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Pediatr Infect Dis J. 2000;19:187–195 · DOI · Paper page
- Jacobs MR. Prevention of otitis media: role of pneumococcal conjugate vaccines in reducing incidence and antibiotic resistance. J Pediatr. 2002;141:287–293 · DOI
- Fireman B, Black SB, Shinefield HR, Lee J, Lewis E, Ray P. Impact of the pneumococcal conjugate vaccine on otitis media. Pediatr Infect Dis J. 2003;22:10–16 · DOI · Paper page
- Eisenberg DM, Davis R, Ettner S, et al. Trends in alternative medicine use in the United States, 1990–1997: results of a follow-up national survey. JAMA. 1998;280:1569–1575 · DOI · Paper page
- Spigelblatt L, Laine-Ammara G, Pless IB, Guyver A. The use of alternative medicine by children. Pediatrics. 1994;94:811–814 · DOI
- Angell M, Kassirer JP. Alternative medicine—the risks of untested and unregulated remedies. N Engl J Med. 1998;339:839–841 · DOI · Paper page
- American Academy of Pediatrics, Committee on Children With Disabilities. Counseling families who choose complementary and alternative medicine for their child with chronic illness or disability. Pediatrics. 2001;107:598–601 · DOI
- Grimm W, Muller HH. A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of colds and respiratory infections. Am J Med. 1999;106:138–143 · DOI · Paper page
- Barret B, Vohmann M, Calabrese C. Echinacea for upper respiratory infection. J Fam Pract. 1999;48:628–635
- van Buchem FL, Dunk JH, van't Hof MA. Therapy of acute otitis media: myringotomy, antibiotics, or neither? A double-blind study in children. Lancet. 1981;2(8252):883–887 · DOI · Paper page
Cited by
The Diagnosis and Management of Acute Otitis Media
Lieberthal, A. S., Carroll, A. E., Chonmaitree, T., Ganiats, T. G., Hoberman, A., Jackson, M. A., Joffe, M. D., Miller, D. T., Rosenfeld, R. M., Sevilla, X. D., et al. (2013) · Pediatrics · doi:10.1542/peds.2012-3488 · Cited by 1,442
Effectiveness of manual therapies: the UK evidence report
Bronfort, G., Haas, M., Evans, R., Leininger, B., & Triano, J. (2010) · Chiropractic & Osteopathy · doi:10.1186/1746-1340-18-3 · Cited by 434
Viral Upper Respiratory Tract Infection and Otitis Media Complication in Young Children
Chonmaitree, T., Revai, K., Grady, J. J., Clos, A., Patel, J. A., Nair, S., Fan, J., & Henrickson, K. J. (2008) · Clinical Infectious Diseases · doi:10.1086/528685 · Cited by 435
Treatment of Acute Otitis Media in Children under 2 Years of Age
Hoberman, A., Paradise, J. L., Rockette, H. E., Shaikh, N., Wald, E. R., Kearney, D. H., Colborn, D. K., Kurs-Lasky, M., Bhatnagar, S., Haralam, M. A., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa0912254 · Cited by 304
Principles of Judicious Antibiotic Prescribing for Upper Respiratory Tract Infections in Pediatrics
Hersh, A. L., Jackson, M. A., Hicks, L. A., the COMMITTEE ON INFECTIOUS DISEASES, Brady, M. T., Byington, C. L., Davies, H. D., Edwards, K. M., Maldonado, Y. A., Murray, D. L., et al. (2013) · Pediatrics · doi:10.1542/peds.2013-3260 · Cited by 266
Metadata
- Authors
- Media, S. O. M. O. A. O.
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2004-05-01
- Volume
- 113
- Issue
- 5
- Pages
- 1451-1465
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W4212974097
- Cited by
- 902
- References
- 1
- FWCI
- 71.21
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Diagnosis and Management of Acute Otitis Media. https://app.cochat.ai/papers/10.1542/peds.113.5.1451
- The paper
- Media, S. O. M. O. A. O. (2004). Diagnosis and Management of Acute Otitis Media. Pediatrics. https://doi.org/10.1542/peds.113.5.1451
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.