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1H NMR chemical shift selective (CHESS) imaging
Abstract
1 H NMR images of human or animal tissues reflect the spatial distribution of both water (H 2 O) and methylene (CH 2 ) proton resonance signals. There are several reasons for a separation of these contributions: (i) the large chemical shift dispersion in high magnetic fields (>or=1.5 T) which leads to an apparent spatial shift in 'composite' images between the superimposed H 2 O and CH 2 images; (ii) the evaluation and interpretation of proton H 2 O and CH 2 relaxation times from NMR images; and (iii) the physiological implications of 'water' and 'fat' distributions for medical diagnosis. The authors describe a chemical shift selective (CHESS) imaging technique which destroys the unwanted signal component by means of a selective 90 degrees excitation pulse and a subsequent magnetic field gradient ('homogeneity spoiling gradient') prior to imaging of the wanted component. The new method allows the creation of either a pure 'water' or 'fat' image.
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Citations
Cited by
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Haroon, E., Woolwine, B. J., Chen, X., Pace, T. W., Parekh, S., Spivey, J. R., Hu, X. P., & Miller, A. H. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.25 · Cited by 154
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Machann, J., Bachmann, O. P., Brechtel, K., Dahl, D. B., Wietek, B., Klumpp, B., Häring, H., Claussen, C. D., Jacob, S., & Schick, F. (2003) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.10255 · Cited by 73
In Vivo Brain GSH: MRS Methods and Clinical Applications
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Metadata
- Authors
- Haase, A., Frahm, J., Hanicke, W., & Matthaei, D.
- Venue
- Physics in Medicine and Biology
- Publisher
- IOP Publishing
- Published
- 1985-04-01
- Volume
- 30
- Issue
- 4
- Pages
- 341-344
- ISSN
- 0031-9155 (ISSN-L)
- 1361-6560
- OpenAlex
- W2000229085
- Cited by
- 1,062
- References
- 0
- FWCI
- 8.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- Haase, A., Frahm, J., Hanicke, W., & Matthaei, D. (1985). 1H NMR chemical shift selective (CHESS) imaging. Physics in Medicine and Biology. https://doi.org/10.1088/0031-9155/30/4/008
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