A closed-loop compressive-sensing-based neural recording system
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OBJECTIVE: This paper describes a low power closed-loop compressive sensing (CS) based neural recording system. This system provides an efficient method to reduce data transmission bandwidth for implantable neural recording devices. By doing so, this technique reduces a majority of system power consumption which is dissipated at data readout interface. The design of the system is scalable and is a viable option for large scale integration of electrodes or recording sites onto a single device. APPROACH: The entire system consists of an application-specific integrated circuit (ASIC) with 4 recording readout channels with CS circuits, a real time off-chip CS recovery block and a recovery quality evaluation block that provides a closed feedback to adaptively adjust compression rate. Since CS performance is strongly signal dependent, the ASIC has been tested in vivo and with standard public neural databases. MAIN RESULTS: Implemented using efficient digital circuit, this system is able to achieve >10 times data compression on the entire neural spike band (500-6KHz) while consuming only 0.83uW (0.53 V voltage supply) additional digital power per electrode. When only the spikes are desired, the system is able to further compress the detected spikes by around 16 times. Unlike other similar systems, the characteristic spikes and inter-spike data can both be recovered which guarantes a >95% spike classification success rate. The compression circuit occupied 0.11mm(2)/electrode in a 180nm CMOS process. The complete signal processing circuit consumes <16uW/electrode. SIGNIFICANCE: Power and area efficiency demonstrated by the system make it an ideal candidate for integration into large recording arrays containing thousands of electrode. Closed-loop recording and reconstruction performance evaluation further improves the robustness of the compression method, thus making the system more practical for long term recording.
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On-chip signal processing, including spike detection and other data compression, is an emerging trend aimed at reducing transmitted data.
“Another emerging trend includes on-chip signal processing, such as spike detection [16, 54] or other forms of data compression [108, 132, 155] to reduce the amount of transmitted data.”
From Implantable neurotechnologies: a review of integrated circuit neural amplifiers (2016) · cites this paper as [155]
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Implantable neurotechnologies: a review of integrated circuit neural amplifiers
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- Authors
- Zhang, J., Mitra, S., Suo, Y., Cheng, A., Xiong, T., Michon, F., Welkenhuysen, M., Kloosterman, F., Chin, P. S., Hsiao, S., Tran, T. D., Yazicioglu, F., & Etienne-Cummings, R.
- Affiliations
- Johns Hopkins University (US)
- IMEC (BE)
- Draper Laboratory (US)
- Corresponding author
- Zhang, Jie
- ORCID
- Venue
- Journal of Neural Engineering
- Publisher
- IOP Publishing
- Published
- 2015-04-15
- Volume
- 12
- Issue
- 3
- Pages
- 036005
- ISSN
- 1741-2552 (ISSN-L)
- 1741-2560
- OpenAlex
- W2058742681
- Cited by
- 33
- References
- 40
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 2 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 4 · 2016: 6 · 2015: 3
- FWCI
- 2.82
- Type
- journal article
- Language
- en
- Open access
- green
- lirias.kuleuven.be
- Licence
- Locations
- Journal of Neural Engineering (publishedVersion)
- PubMed (publishedVersion)
- Lirias (submittedVersion, other-oa)
- ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
- Funders
- Army Research Office (60219-MA)
- U.S. National Science Foundation (1057644)
- Office of Naval Research (N000141210765)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
- Physical Sciences › Engineering › Computational Mechanics › Sparse and Compressive Sensing Techniques
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Keywords
- compressed sensing, neural recording, implantable neural interfaces, low-power ASIC, spike classification, CMOS circuit design
- MeSH terms
- Algorithms, Analog-Digital Conversion, Animals, Brain, Electroencephalography, Equipment Design, Feedback, Electric Power Supplies, Sensitivity and Specificity, Signal Processing, Computer-Assisted, Reproducibility of Results, Equipment Failure Analysis, Data Compression, Rats, Signal-To-Noise Ratio
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