Cited by 184Analog and Mixed-Signal Circuit DesignNeuroscience and Neural EngineeringCCD and CMOS Imaging Sensors

256-Channel Neural Recording and Delta Compression Microsystem With 3D Electrodes

Aziz, Joseph N. Y., Abdelhalim, Karim, Shulyzki, Ruslana, Genov, Roman, Bardakjian, Berj L., Derchansky, Miron, Serletis, Demitre, Carlen, Peter L.·2009·IEEE Journal of Solid-State Circuits

Abstract

A 3D microsystem for multi-site penetrating extracellular neural recording from the brain is presented. A 16 times 16-channel neural recording interface integrated prototype fabricated in 0.35 mum CMOS occupies 3.5 mm times 4.5 mm area. Each recording channel dissipates 15 muW of power with input-referred noise of 7 muVrmsover 5 kHz bandwidth. A switched-capacitor delta read-out data compression circuit trades recording accuracy for the output data rate. An array of 1.5 mm platinum-coated microelectrodes is bonded directly onto the die. Results of in vitro experimental recordings from intact mouse hippocampus validate the circuit design and the on-chip electrode bonding technology.

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Registry

Crossref · 10.1109/jssc.2008.2010997

Cites

25 of 25 references verified0 citation errors · 0 not checkable

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  • Continued shrinking of fine-line CMOS processes has helped increase channel counts and add capabilities such as on-chip analog-to-digital conversion and digital radio transmission.

    “The steady reduction in fine-line CMOS technologies has contributed to increased channel counts [6, 77] and expanded capabilities, such as on-chip analog-to-digital conversion [49, 156] and digital radio transmission [16, 67].”

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Authors
Aziz, J. N. Y., Abdelhalim, K., Shulyzki, R., Genov, R., Bardakjian, B. L., Derchansky, M., Serletis, D., & Carlen, P. L.
Affiliations
University of Toronto (CA)
Venue
IEEE Journal of Solid-State Circuits
Published
2009-03
Volume
44
Issue
3
Pages
995-1005
ISSN
0018-9200 (ISSN-L)
OpenAlex
W2141731119
Cited by
184
References
25
Citations by year
2026: 1 · 2025: 4 · 2024: 3 · 2023: 6 · 2022: 7 · 2021: 13 · 2020: 4 · 2019: 7 · 2018: 9 · 2017: 11 · 2016: 10 · 2015: 13 · 2014: 19 · 2013: 20 · 2012: 11
FWCI
11.21
Type
journal article
Language
en
Open access
closed
Locations
IEEE Journal of Solid-State Circuits (publishedVersion)
Funders
CMC Microsystems
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
  • Physical Sciences › Engineering › Electrical and Electronic Engineering › CCD and CMOS Imaging Sensors
Keywords
neural recording, delta compression, data compression, low-power readout circuit, mouse hippocampus

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