Assessment methodologies for extrusion-based bioink printability
Open accessAbstract
Extrusion-based bioprinting is one of the leading manufacturing techniques for tissue engineering and regenerative medicine. Its primary limitation is the lack of materials, known as bioinks, which are suitable for the bioprinting process. The degree to which a bioink is suitable for bioprinting has been described as its ‘printability.’ However, a lack of clarity surrounding the methodologies used to evaluate a bioink’s printability, as well as the usage of the term itself, have hindered the field. This article presents a review of measures used to assess the printability of extrusion-based bioinks in an attempt to assist researchers during the bioink development process. Many different aspects of printability exist and many different measurements have been proposed as a consequence. Researchers often do not evaluate a new bioink’s printability at all, while others simply do so qualitatively. Several quantitative measures have been presented for the extrudability, shape fidelity, and printing accuracy of bioinks. Different measures have been developed even within these aspects, each testing the bioink in a slightly different way. Additionally, other relevant measures which had little or no examples of quantifiable methods are also to be considered. Looking forward, further work is needed to improve upon current assessment methodologies, to move towards a more comprehensive view of printability, and to standardize these printability measurements between researchers. Better assessment techniques will naturally lead to a better understanding of the underlying mechanisms which affect printability and better comparisons between bioinks. This in turn will help improve upon the bioink development process and the bioinks available for use in bioprinting.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Extrusion-based bioprinting is the most widely used bioprinting technique owing to its versatility and compatibility with hydrogel-based bioinks.
“Among the available techniques, extrusion-based bioprinting is the most widely used owing to its versatility and compatibility with hydrogel-based bioinks [4,5,6].”
Although the spreading ratio tended to decrease with increasing MMT concentration, no statistically significant differences were observed among the formulations (one-way ANOVA, p = 0.117).
“Although the spreading ratio (Figure 6D) tended to decrease with increasing MMT concentration, no statistically significant differences were observed among the formulations (one-way ANOVA, p = 0.117) [6,7].”
From Montmorillonite-reinforced methacrylated collagen/methacrylated silk fibroin hydrogel-based inks: rheological and physicochemical characterization for bone scaffold applications (2026) · cites this paper as [6]
The Shape fidelity > Filament spreading section discusses spreading ratio as a measure of printed filament width, but does not report results for MMT formulations. Searches for MMT concentration, montmorillonite, and p = 0.117 found no passage addressing the claimed trend or ANOVA result; page numbers were not available in our copy. (LLM, conf=0.75)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
3D bioprinting of tissues and organs
Murphy, S. V., & Atala, A. (2014) · Nature Biotechnology · doi:10.1038/nbt.2958 · Cited by 7,034 · see citing works
Self-citationA 3D bioprinting system to produce human-scale tissue constructs with structural integrity
Kang, H.-W., Lee, S. J., Ko, I. K., Kengla, C., Yoo, J. J., & Atala, A. (2016) · Nature Biotechnology · doi:10.1038/nbt.3413 · Cited by 2,622 · see citing works
Self-citation25th Anniversary Article: Engineering Hydrogels for Biofabrication
Malda, J., Visser, J., Melchels, F. P., Jüngst, T., Hennink, W. E., Dhert, W. J. A., Groll, J., & Hutmacher, D. W. (2013) · Advanced Materials · doi:10.1002/adma.201302042 · Cited by 1,901 · see citing works
3D bioprinting for engineering complex tissues
Mandrycky, C., Wang, Z., Kim, K., & Kim, D. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.12.011 · Cited by 1,768 · see citing works
Markstedt, K., Mantas, A., Tournier, I., Martínez Ávila, H., Hägg, D., & Gatenholm, P. (2015) · Biomacromolecules · doi:10.1021/acs.biomac.5b00188 · Cited by 1,528 · see citing works
The bioink: A comprehensive review on bioprintable materials
Hospodiuk, M., Dey, M., Sosnoski, D. M., & Ozbolat, I. T. (2017) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.12.006 · Cited by 1,139 · see citing works
Bioink properties before, during and after 3D bioprinting
Hölzl, K., Lin, S., Tytgat, L., Vlierberghe, S. V., Gu, L., & Ovsianikov, A. (2016) · Biofabrication · doi:10.1088/1758-5090/8/3/032002 · Cited by 1,087 · see citing works
Ouyang, L., Yao, R., Zhao, Y., & Sun, W. (2016) · Biofabrication · doi:10.1088/1758-5090/8/3/035020 · Cited by 1,052 · see citing works
3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
Derakhshanfar, S., Mbeleck, R., Xu, K., Zhang, X., Zhong, W., & Xing, M. M. Q. (2018) · Bioactive Materials · doi:10.1016/j.bioactmat.2017.11.008 · Cited by 1,040 · see citing works
3D Bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels
Duan, B., Hockaday, L. A., Kang, K. H., & Butcher, J. T. (2012) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34420 · Cited by 1,005 · see citing works
Paxton, N. C., Smolan, W., Bock, T. A., Melchels, F. P. W., Gröll, J., & Jüngst, T. (2017) · Biofabrication · doi:10.1088/1758-5090/aa8dd8 · Cited by 959 · see citing works
Recent trends in bioinks for 3D printing
Janarthanan, G., & Noh, I. (2018) · Biomaterials Research · doi:10.1186/s40824-018-0122-1 · Cited by 852 · see citing works
A definition of bioinks and their distinction from biomaterial inks
Gröll, J., Burdick, J. A., Cho, D.-W., Derby, B., Gelinsky, M., Heilshorn, S. C., Jüngst, T., Malda, J., Mironov, V. A., Nakayama, K., et al. (2018) · Biofabrication · doi:10.1088/1758-5090/aaec52 · Cited by 808 · see citing works
Self-citationSchuurman, W., Levett, P. A., Pot, M. W., van Weeren, P. R., Dhert, W. J. A., Hutmacher, D. W., Melchels, F. P. W., Klein, T. J., & Malda, J. (2013) · Macromolecular Bioscience · doi:10.1002/mabi.201200471 · Cited by 791 · see citing works
Designing Biomaterials for 3D Printing
Güvendiren, M., Molde, J., Soares, R. M. D., & Kohn, J. (2016) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.6b00121 · Cited by 737 · see citing works
Biofabrication: reappraising the definition of an evolving field
Groll, J., Boland, T., Blunk, T., Burdick, J. A., Cho, D.-W., Dalton, P. D., Derby, B., Forgacs, G., Li, Q., Mironov, V. A., et al. (2016) · Biofabrication · doi:10.1088/1758-5090/8/1/013001 · Cited by 731 · see citing works
Self-citationStrategies and Molecular Design Criteria for 3D Printable Hydrogels
Jüngst, T., Smolan, W., Schacht, K., Scheibel, T., & Gröll, J. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00303 · Cited by 716 · see citing works
Advanced Bioinks for 3D Printing: A Materials Science Perspective
Chimene, D., Lennox, K. K., Kaunas, R. R., & Gaharwar, A. K. (2016) · Annals of Biomedical Engineering · doi:10.1007/s10439-016-1638-y · Cited by 680 · see citing works
Research on the printability of hydrogels in 3D bioprinting
He, Y., Yang, F., Zhao, H., Gao, Q., Xia, B., & Fu, J. (2016) · Scientific Reports · doi:10.1038/srep29977 · Cited by 656 · see citing works
Biofabrication: A Guide to Technology and Terminology
Moroni, L., Boland, T., Burdick, J. A., Maria, C. D., Derby, B., Forgács, G., Gröll, J., Li, Q., Malda, J., Mironov, V. A., et al. (2017) · Trends in biotechnology · doi:10.1016/j.tibtech.2017.10.015 · Cited by 643 · see citing works
Self-citationLanders, R., Hübner, U., Schmelzeisen, R., & Mülhaupt, R. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00139-4 · Cited by 627 · see citing works
Bio-ink properties and printability for extrusion printing living cells
Chung, J. H.-Y., Naficy, S., Yue, Z., Kapsa, R. M. I., Quigley, A. F., Moulton, S. E., & Wallace, G. G. (2013) · Biomaterials Science · doi:10.1039/c3bm00012e · Cited by 612 · see citing works
A Multimaterial Bioink Method for 3D Printing Tunable, Cell‐Compatible Hydrogels
Rutz, A. L., Hyland, K. E., Jakus, A. E., Burghardt, W. R., & Shah, R. N. (2015) · Advanced Materials · doi:10.1002/adma.201405076 · Cited by 573 · see citing works
Das, S., Pati, F., Choi, Y., Rijal, G., Shim, J., Kim, S. W., Ray, A. R., Cho, D., & Ghosh, S. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.09.023 · Cited by 557 · see citing works
Evaluation of hydrogels for bio‐printing applications
Murphy, S. V., Skardal, A., & Atala, A. (2012) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34326 · Cited by 547 · see citing works
Self-citationLaronda, M. M., Rutz, A. L., Xiao, S., Whelan, K. A., Duncan, F. E., Roth, E. W., Woodruff, T. K., & Shah, R. N. (2017) · Nature Communications · doi:10.1038/ncomms15261 · Cited by 531 · see citing works
Gao, T., Gillispie, G. J., Copus, J. S., Anil Kumar, P. R., Seol, Y., Atala, A., Yoo, J. J., & Lee, S. J. (2018) · Biofabrication · doi:10.1088/1758-5090/aacdc7 · Cited by 519 · see citing works
Self-citation‘Printability' of Candidate Biomaterials for Extrusion Based 3D Printing: State‐of‐the‐Art
Kyle, S., Jessop, Z. M., Al‐Sabah, A., & Whitaker, I. S. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700264 · Cited by 497 · see citing works
Current Status of Bioinks for Micro-Extrusion-Based 3D Bioprinting
Panwar, A., & Tan, L. P. (2016) · Molecules · doi:10.3390/molecules21060685 · Cited by 478 · see citing works
Assessing bioink shape fidelity to aid material development in 3D bioprinting
Ribeiro, A., Blokzijl, M. M., Levato, R., Visser, C. W., Castilho, M. D., Hennink, W. E., Vermonden, T., & Malda, J. (2017) · Biofabrication · doi:10.1088/1758-5090/aa90e2 · Cited by 456 · see citing works
Direct‐write bioprinting three‐dimensional biohybrid systems for future regenerative therapies
Chang, C. C., Boland, E. D., Williams, S. K., & Hoying, J. B. (2011) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.31831 · Cited by 446 · see citing works
Duan, B., Kapetanovic, E., Hockaday, L. A., & Butcher, J. T. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.12.005 · Cited by 437 · see citing works
A comparison of different bioinks for 3D bioprinting of fibrocartilage and hyaline cartilage
Daly, A. C., Critchley, S. E., Rencsok, E. M., & Kelly, D. J. (2016) · Biofabrication · doi:10.1088/1758-5090/8/4/045002 · Cited by 436 · see citing works
Mechanical behaviour of alginate-gelatin hydrogels for 3D bioprinting
Giuseppe, M. D., Law, N., Webb, B., Macrae, R. A., Liew, L. J., Sercombe, T. B., Dilley, R. J., & Doyle, B. J. (2017) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2017.12.018 · Cited by 395 · see citing works
Three-dimensional bioprinting of complex cell laden alginate hydrogel structures
Tabriz, A. G., Hermida, M. A., Leslie, N. R., & Shu, W. (2015) · Biofabrication · doi:10.1088/1758-5090/7/4/045012 · Cited by 394 · see citing works
Alginate Sulfate–Nanocellulose Bioinks for Cartilage Bioprinting Applications
Müller, M., Öztürk, E., Arlov, Ø., Gatenholm, P., & Zenobi‐Wong, M. (2016) · Annals of Biomedical Engineering · doi:10.1007/s10439-016-1704-5 · Cited by 392 · see citing works
A bioprintable form of chitosan hydrogel for bone tissue engineering
Demirtaş, T. T., Irmak, G., & Gümüşderelı́oğlu, M. (2017) · Biofabrication · doi:10.1088/1758-5090/aa7b1d · Cited by 380 · see citing works
A 3D bioprinted complex structure for engineering the muscle–tendon unit
Merceron, T. K., Burt, M. A., Seol, Y., Kang, H.-W., Lee, S. J., Yoo, J. J., & Atala, A. (2015) · Biofabrication · doi:10.1088/1758-5090/7/3/035003 · Cited by 373 · see citing works
Self-citationNanostructured Pluronic hydrogels as bioinks for 3D bioprinting
Müller, M., Becher, J., Schnabelrauch, M., & Zenobi‐Wong, M. (2015) · Biofabrication · doi:10.1088/1758-5090/7/3/035006 · Cited by 372 · see citing works
Shear-Thinning and Thermo-Reversible Nanoengineered Inks for 3D Bioprinting
Wilson, S. A., Cross, L., Peak, C. W., & Gaharwar, A. K. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b13602 · Cited by 370 · see citing works
Mouser, V. H. M., Melchels, F. P. W., Visser, J., Dhert, W. J. A., Gawlitta, D., & Malda, J. (2016) · Biofabrication · doi:10.1088/1758-5090/8/3/035003 · Cited by 360 · see citing works
Wüst, S., Godla, M. E., Müller, R., & Hofmann, S. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.10.016 · Cited by 357 · see citing works
3D Printability of Alginate-Carboxymethyl Cellulose Hydrogel
Habib, A., Sathish, V., Mallik, S., & Khoda, B. (2018) · Materials · doi:10.3390/ma11030454 · Cited by 332 · see citing works
Bendtsen, S. T., Quinnell, S. P., & Wei, M. (2017) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36036 · Cited by 330 · see citing works
Zhao, Y., Li, Y., Mao, S., Sun, W., & Yao, R. (2015) · Biofabrication · doi:10.1088/1758-5090/7/4/045002 · Cited by 312 · see citing works
Development of a clay based bioink for 3D cell printing for skeletal application
Ahlfeld, T., Cidonio, G., Kilian, D., Duin, S., Akkineni, A. R., Dawson, J. I., Yang, S., Lode, A., Oreffo, R. O. C., & Gelinsky, M. (2017) · Biofabrication · doi:10.1088/1758-5090/aa7e96 · Cited by 303 · see citing works
3D bioprinted functional and contractile cardiac tissue constructs
Wang, Z., Lee, S. J., Cheng, H.-J., Yoo, J. J., & Atala, A. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.02.007 · Cited by 301 · see citing works
Self-citationKesti, M., Müller, M., Becher, J., Schnabelrauch, M., D’Este, M., Eglin, D., & Zenobi‐Wong, M. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.09.033 · Cited by 295 · see citing works
Polyelectrolyte gelatin-chitosan hydrogel optimized for 3D bioprinting in skin tissue engineering
Ng, W. L., Yeong, W. Y., & Naing, M. W. (2016) · International Journal of Bioprinting · doi:10.18063/ijb.2016.01.009 · Cited by 294 · see citing works
3D Bioprinted Human Skeletal Muscle Constructs for Muscle Function Restoration
Kim, J. H., Seol, Y., Ko, I. K., Kang, H.-W., Lee, Y. K., Yoo, J. J., Atala, A., & Lee, S. J. (2018) · Scientific Reports · doi:10.1038/s41598-018-29968-5 · Cited by 294 · see citing works
Self-citationDiamantides, N., Wang, L., Pruiksma, T., Siemiatkoski, J., Dugopolski, C., Shortkroff, S., Kennedy, S. M., & Bonassar, L. J. (2017) · Biofabrication · doi:10.1088/1758-5090/aa780f · Cited by 254 · see citing works
3D Bioprinting of Highly Thixotropic Alginate/Methylcellulose Hydrogel with Strong Interface Bonding
Li, H., Tan, Y. J., Leong, K. F., & Li, L. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b04216 · Cited by 250 · see citing works
Rheological study on 3D printability of alginate hydrogel and effect of graphene oxide
Li, H., Liu, S., & Li, L. (2017) · International Journal of Bioprinting · doi:10.18063/ijb.2016.02.007 · Cited by 243 · see citing works
Synthesis and Characterization of Types A and B Gelatin Methacryloyl for Bioink Applications
Lee, B., Lum, N., Seow, L., Lim, P., & Tan, L. P. (2016) · Materials · doi:10.3390/ma9100797 · Cited by 243 · see citing works
Biofabrication of Cell‐Loaded 3D Spider Silk Constructs
Schacht, K., Jüngst, T., Schweinlin, M., Ewald, A., Gröll, J., & Scheibel, T. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201409846 · Cited by 232 · see citing works
Campos, D. F. D., Blaeser, A., Korsten, A., Neuß, S., Jäkel, J., Vogt, M., & Fischer, H. (2014) · Tissue Engineering Part A · doi:10.1089/ten.tea.2014.0231 · Cited by 229 · see citing works
Development and characterisation of a new bioink for additive tissue manufacturing
Melchels, F. P. W., Dhert, W. J. A., Hutmacher, D. W., & Malda, J. (2014) · Journal of Materials Chemistry B · doi:10.1039/c3tb21280g · Cited by 222 · see citing works
3D bioprinting of liver-mimetic construct with alginate/cellulose nanocrystal hybrid bioink
Wu, Y., Lin, Z. Y., Wenger, A., Tam, K. C., & Tang, X. S. (2017) · Bioprinting · doi:10.1016/j.bprint.2017.12.001 · Cited by 209 · see citing works
Advancing the field of 3D biomaterial printing
Jakus, A. E., Rutz, A. L., & Shah, R. N. (2016) · Biomedical Materials · doi:10.1088/1748-6041/11/1/014102 · Cited by 203 · see citing works
Parameter optimization for 3D bioprinting of hydrogels
Webb, B., & Doyle, B. J. (2017) · Bioprinting · doi:10.1016/j.bprint.2017.09.001 · Cited by 190 · see citing works
Athirasala, A., Tahayeri, A., Thrivikraman, G., França, C. M., Monteiro, N., Tran, V., Ferracane, J. L., & Bertassoni, L. E. (2017) · Biofabrication · doi:10.1088/1758-5090/aa9b4e · Cited by 190 · see citing works
Suntornnond, R., Tan, E. Y. S., An, J., & Chua, C. K. (2017) · Scientific Reports · doi:10.1038/s41598-017-17198-0 · Cited by 184 · see citing works
Optimization of cell-laden bioinks for 3D bioprinting and efficient infection with influenza A virus
Berg, J., Hiller, T., Kissner, M. S., Qazi, T. H., Duda, G. N., Hocke, A. C., Hippenstiel, S., Elomaa, L., Weinhart, M., Fahrenson, C., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-31880-x · Cited by 172 · see citing works
Ahn, G., Min, K., Kim, C., Lee, S., Kang, D., Won, J.-Y., Cho, D., Kim, J., Jin, S., Yun, W., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-09201-5 · Cited by 165 · see citing works
Self-citationTuning Alginate-Gelatin Bioink Properties by Varying Solvent and Their Impact on Stem Cell Behavior
Li, Z., Huang, S., Liu, Y., Yao, B., Hu, T. H., Shi, H., Xie, J., & Fu, X. (2018) · Scientific Reports · doi:10.1038/s41598-018-26407-3 · Cited by 165 · see citing works
Jin, Y., Chai, W., & Huang, Y. H. (2017) · Materials Science and Engineering C · doi:10.1016/j.msec.2017.05.144 · Cited by 159 · see citing works
Characterisation of hyaluronic acid methylcellulose hydrogels for 3D bioprinting
Law, N., Doney, B., Glover, H., Qin, Y., Aman, Z. M., Sercombe, T. B., Liew, L. J., Dilley, R. J., & Doyle, B. J. (2017) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2017.09.031 · Cited by 158 · see citing works
Biomimetic Inks Based on Cellulose Nanofibrils and Cross-Linkable Xylans for 3D Printing
Markstedt, K., Escalante, A., Toríz, G., & Gatenholm, P. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b13400 · Cited by 143 · see citing works
Bioprinted chitosan-gelatin thermosensitive hydrogels using an inexpensive 3D printer
Roehm, K. D., & Madihally, S. V. (2017) · Biofabrication · doi:10.1088/1758-5090/aa96dd · Cited by 133 · see citing works
Abbadessa, A., Mouser, V. H. M., Blokzijl, M. M., Gawlitta, D., Dhert, W. J. A., Hennink, W. E., Malda, J., & Vermonden, T. (2016) · Biomacromolecules · doi:10.1021/acs.biomac.6b00366 · Cited by 132 · see citing works
Simulations of 3D bioprinting: predicting bioprintability of nanofibrillar inks
Göhl, J., Markstedt, K., Mark, A., Håkansson, K. M. O., Gatenholm, P., & Edelvik, F. (2018) · Biofabrication · doi:10.1088/1758-5090/aac872 · Cited by 132 · see citing works
3D Printing of Ultratough Polyion Complex Hydrogels
Zhu, F., Cheng, L., Yin, J., Wu, Z. L., Qian, J. W., Fu, J., & Zheng, Q. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b09881 · Cited by 131 · see citing works
Köpf, M., Campos, D. F. D., Blaeser, A., Sen, K. S., & Fischer, H. (2016) · Biofabrication · doi:10.1088/1758-5090/8/2/025011 · Cited by 114 · see citing works
Quantitative optimization of solid freeform deposition of aqueous hydrogels
Kang, K. H., Hockaday, L. A., & Butcher, J. T. (2013) · Biofabrication · doi:10.1088/1758-5082/5/3/035001 · Cited by 110 · see citing works
A phase diagram for microfabrication of geometrically controlled hydrogel scaffolds
Tirella, A., Orsini, A. A., Vozzi, G., & Ahluwalia, A. D. (2009) · Biofabrication · doi:10.1088/1758-5082/1/4/045002 · Cited by 104 · see citing works
Sweeney, M., Campbell, L. L., Hanson, J. M., Pantoya, M. L., & Christopher, G. F. (2017) · Journal of Materials Science · doi:10.1007/s10853-017-1404-z · Cited by 101 · see citing works
Chakrabarti, A., & Chaudhury, M. K. (2013) · Langmuir · doi:10.1021/la401115j · Cited by 99 · see citing works
Three-Dimensional Bioprinting of Oppositely Charged Hydrogels with Super Strong Interface Bonding
Li, H., Tan, Y. J., Liu, S., & Li, L. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b19730 · Cited by 99 · see citing works
Blaeser, A., Campos, D. F. D., Weber, M. H., Neuß, S., Theek, B., Fischer, H., & Jahnen‐Dechent, W. (2013) · BioResearch open access · doi:10.1089/biores.2013.0031 · Cited by 95 · see citing works
Sarker, M. D., & Chen, D. (2017) · Journal of Manufacturing Science and Engineering · doi:10.1115/1.4036226 · Cited by 88 · see citing works
Increased Mixing Improves Hydrogel Homogeneity and Quality of Three-Dimensional Printed Constructs
Cohen, D. L., Lo, W. M., Tsavaris, A. M., Peng, D. H., Lipson, H., & Bonassar, L. J. (2010) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2010.0093 · Cited by 87 · see citing works
Assessment of hydrogels for bioprinting of endothelial cells
Benning, L., Gutzweiler, L., Tröndle, K., Riba, J., Zengerle, R., Koltay, P., Zimmermann, S., Stark, G. B., & Finkenzeller, G. (2017) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36291 · Cited by 82 · see citing works
Phage as versatile nanoink for printing 3-D cell-laden scaffolds
Lee, D.-Y., Lee, H., Kim, Y., Yoo, S. Y., Chung, W., & Kim, G. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.10.004 · Cited by 80 · see citing works
Lee, J. M., & Yeong, W. Y. (2014) · Virtual and Physical Prototyping · doi:10.1080/17452759.2014.979557 · Cited by 79 · see citing works
Shape fidelity and structure of 3D printed high consistency nanocellulose
Klar, V., Pere, J., Turpeinen, T., Kärki, P., Orelma, H., & Kuosmanen, P. (2019) · Scientific Reports · doi:10.1038/s41598-019-40469-x · Cited by 76 · see citing works
Three-dimensional cell-based bioprinting for soft tissue regeneration
Kim, J. H., Yoo, J. J., & Lee, S. J. (2016) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-016-0133-8 · Cited by 70 · see citing works
Self-citationPrintable Fluorescent Hydrogels Based on Self-Assembling Peptides
Xia, Y., Xue, B., Qin, M., Cao, Y., Li, Y., & Wang, W. (2017) · Scientific Reports · doi:10.1038/s41598-017-10162-y · Cited by 68 · see citing works
Rheological Properties of Cell-Hydrogel Composites Extruding Through Small-Diameter Tips
Cheng, J., Lin, F., Liu, H., Yan, Y., Wang, X., Zhang, R., & Xiong, Z. (2008) · Journal of Manufacturing Science and Engineering · doi:10.1115/1.2896215 · Cited by 66 · see citing works
Three-Dimensional Cell Printing of Large-Volume Tissues: Application to Ear Regeneration
Lee, J., Kim, B. S., Seo, D., Park, J., & Cho, D. (2017) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2016.0362 · Cited by 51 · see citing works
Wang, X., He, K., & Zhang, W. (2013) · Journal of Bioactive and Compatible Polymers · doi:10.1177/0883911513491359 · Cited by 44 · see citing works
Kraut, G., Yenchesky, L., Prieto, F., Tovar, G. E. M., & Southan, A. (2017) · Journal of Applied Polymer Science · doi:10.1002/app.45083 · Cited by 29 · see citing works
Dahal, E., Badal, A., Zidan, A. S., Alayoubi, A. Y., Hagio, T., Glick, S. J., Badano, A. G., & Ghammraoui, B. (2018) · Physics in Medicine and Biology · doi:10.1088/1361-6560/aabd1f · Cited by 23 · see citing works
Assessing printability of bioinks
Kyle, S., Jessop, Z. M., Tarassoli, S. P., Al‐Sabah, A., & Whitaker, I. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-08-101103-4.00027-2 · Cited by 17 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Printability and shape fidelity of bioinks in 3D bioprinting
Schwab, A., Levato, R., D’Este, M., Piluso, S., Eglin, D., & Malda, J. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00084 · Cited by 1,359 · see citing works
Rheological characterisation of ceramic inks for 3D direct ink writing: A review
del‐Mazo‐Barbara, L., & Ginebra, M. (2021) · Journal of the European Ceramic Society · doi:10.1016/j.jeurceramsoc.2021.08.031 · Cited by 455 · see citing works
Zhang, Y. S., Haghiashtiani, G., Hübscher, T., Kelly, D. J., Lee, J. M., Lütolf, M. P., McAlpine, M. C., Yeong, W. Y., Zenobi‐Wong, M., & Malda, J. (2021) · Nature Reviews Methods Primers · doi:10.1038/s43586-021-00073-8 · Cited by 407 · see citing works
Daly, A. C., Prendergast, M. E., Hughes, A. J., & Burdick, J. A. (2021) · Cell · doi:10.1016/j.cell.2020.12.002 · Cited by 345 · see citing works
Collagen- and hyaluronic acid-based hydrogels and their biomedical applications
Xu, Q., Torres, J. E., Hakim, M. H., Babiak, P. M., Pal, P., Battistoni, C. M., Nguyen, M. B., Panitch, A., Solorio, L., & Liu, J. C. (2021) · Materials Science and Engineering R Reports · doi:10.1016/j.mser.2021.100641 · Cited by 326 · see citing works
The rheology of direct and suspended extrusion bioprinting
Cooke, M. E., & Rosenzweig, D. H. (2021) · APL Bioengineering · doi:10.1063/5.0031475 · Cited by 296 · see citing works
Printability–A key issue in extrusion-based bioprinting
Naghieh, S., & Chen, D. (2021) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2021.02.001 · Cited by 275 · see citing works
Polymeric Systems for Bioprinting
Bedell, M. L., Navara, A. M., Du, Y., Zhang, S., & Mikos, A. G. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00834 · Cited by 263 · see citing works
Self-citationPhysical and Chemical Factors Influencing the Printability of Hydrogel-based Extrusion Bioinks
Lee, S. C., Gillispie, G. J., Prim, P. M., & Lee, S. J. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00015 · Cited by 264 · see citing works
Self-citationExtrusion bioprinting: Recent progress, challenges, and future opportunities
Ramesh, S., Harrysson, O. L. A., Rao, P., Tamayol, A., Cormier, D., Zhang, Y., & Rivero, I. V. (2020) · Bioprinting · doi:10.1016/j.bprint.2020.e00116 · Cited by 244 · see citing works
3D Bioprinting of Cell‐Laden Hydrogels for Improved Biological Functionality
Hull, S. M., Brunel, L. G., & Heilshorn, S. C. (2021) · Advanced Materials · doi:10.1002/adma.202103691 · Cited by 244 · see citing works
Bom, S., Ribeiro, R., Ribeiro, H. M., Santos, C., & Marto, J. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121506 · Cited by 230 · see citing works
Natural Biomaterials and Their Use as Bioinks for Printing Tissues
Benwood, C., Chrenek, J., Kirsch, R. L., Masri, N. Z., Richards, H., Teetzen, K., & Willerth, S. M. (2021) · Bioengineering · doi:10.3390/bioengineering8020027 · Cited by 230 · see citing works
3D bioprinting and its innovative approach for biomedical applications
Tripathi, S., Mandal, S. S., Bauri, S., & Maiti, P. (2022) · MedComm · doi:10.1002/mco2.194 · Cited by 208 · see citing works
Printability in extrusion bioprinting
Fu, Z., Naghieh, S., Xu, C., Wang, C., Sun, W., & Chen, D. (2021) · Biofabrication · doi:10.1088/1758-5090/abe7ab · Cited by 198 · see citing works
3D Printing of Microgel Scaffolds with Tunable Void Fraction to Promote Cell Infiltration
Seymour, A. J., Shin, S., & Heilshorn, S. C. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100644 · Cited by 158 · see citing works
3D Printing of Hydrogels for Stretchable Ionotronic Devices
Ge, G., Wang, Q., Zhang, Y., Alshareef, H. N., & Dong, X. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202107437 · Cited by 151 · see citing works
Theus, A. S., Ning, L., Hwang, B., Gil, C. J., Chen, S., Wombwell, A., Mehta, R., & Serpooshan, V. (2020) · Polymers · doi:10.3390/polym12102262 · Cited by 150 · see citing works
3D printed carboxymethyl cellulose scaffolds for autologous growth factors delivery in wound healing
Díaz-Gómez, L. A., Gonzalez-Prada, I., Millán, R., da Silva‐Candal, A., Bugallo-Casal, A., Campos, F., Concheiro, Á., & Alvarez‐Lorenzo, C. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.118924 · Cited by 142 · see citing works
Todd, E. A., Mirsky, N. A., Silva, B. L. G., Shinde, A. R., Arakelians, A. R. L., Nayak, V. V., Marcantonio, R. A. C., Gupta, N., Witek, L., & Coelho, P. G. (2024) · Journal of Functional Biomaterials · doi:10.3390/jfb15100280 · Cited by 130 · see citing works
Classification, processing, and applications of bioink and 3D bioprinting: A detailed review
Raees, S., Ullah, F., Javed, F. T., Akil, H. M., Khan, M. J., Safdar, M. M., Din, I. U., Alotaibi, M. A., Alharthi, A. I., Bakht, M. A., et al. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.123476 · Cited by 120 · see citing works
3D printing of bio-instructive materials: Toward directing the cell
Zieliński, P. S., Gudeti, P. K. R., Rikmanspoel, T., & Włodarczyk‐Biegun, M. K. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.04.008 · Cited by 119 · see citing works
Calafel, I., Criado‐Gonzalez, M., Aguirresarobe, R., Fernández, M., & Mijangos, C. (2025) · Materials Advances · doi:10.1039/d5ma00019j · Cited by 123 · see citing works
3D Printing of Self‐Healing Materials
Roppolo, I., Caprioli, M., Pirri, C. F., & Magdassi, S. (2023) · Advanced Materials · doi:10.1002/adma.202305537 · Cited by 113 · see citing works
Polysaccharide-Based Bioink Formulation for 3D Bioprinting of an In Vitro Model of the Human Dermis
Zidarič, T., Milojević, M., Gradišnik, L., Kleinschek, K. S., Maver, U., & Maver, T. (2020) · Nanomaterials · doi:10.3390/nano10040733 · Cited by 105 · see citing works
AI-driven 3D bioprinting for regenerative medicine: From bench to bedside
Zhang, Z., Zhou, X., Fang, Y., Xiong, Z., & Zhang, T. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.11.021 · Cited by 121 · see citing works
Biomaterials for extrusion-based bioprinting and biomedical applications
Rossi, A., Pescara, T., Gambelli, A. M., Gaggia, F., Asthana, A., Perrier, Q., Basta, G., Moretti, M., Senin, N., Rossi, F., et al. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1393641 · Cited by 101 · see citing works
Boularaoui, S. M., Shanti, A., Lanotte, M., Luo, S., Bawazir, S. S., Lee, S., Christoforou, N., Khan, K. A., & Stefanini, C. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c01193 · Cited by 99 · see citing works
Self-citationLee, S. J., Jeong, W., & Atala, A. (2024) · Advanced Materials · doi:10.1002/adma.202408032 · Cited by 102 · see citing works
Self-citationJanarthanan, G., Tran, H. N., Cha, E., Lee, C., Das, D., & Noh, I. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.111008 · Cited by 93 · see citing works
Ataie, Z., Kheirabadi, S., Zhang, J. W., Kedzierski, A., Petrosky, C., Jiang, R., Vollberg, C., & Sheikhi, A. (2022) · Small · doi:10.1002/smll.202202390 · Cited by 84 · see citing works
Gorroñogoitia, I., Urtaza, U., Zubiarrain-Laserna, A., Alonso‐Varona, A., & Zaldua, A. M. (2022) · Polymers · doi:10.3390/polym14020354 · Cited by 83 · see citing works
Advances in 3D bioprinting for regenerative medicine applications
Loukelis, K., Koutsomarkos, N., Mikos, A. G., & Chatzinikolaidou, Μ. (2024) · Regenerative Biomaterials · doi:10.1093/rb/rbae033 · Cited by 88 · see citing works
Self-citationRecent advancements in the bioprinting of vascular grafts
Fazal, F., Raghav, S., Callanan, A., Koutsos, V., & Radacsi, N. (2021) · Biofabrication · doi:10.1088/1758-5090/ac0963 · Cited by 81 · see citing works
Reina-Romo, E., Mandal, S., Amorim, P. A., Bloemen, V., Ferraris, E., & Geris, L. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.701778 · Cited by 81 · see citing works
Improved accuracy and precision of bioprinting through progressive cavity pump-controlled extrusion
Fisch, P., Holub, M., & Zenobi‐Wong, M. (2020) · Biofabrication · doi:10.1088/1758-5090/abc39b · Cited by 80 · see citing works
Chaudhary, S., & Chakraborty, E. (2022) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1186/s43088-021-00172-1 · Cited by 79 · see citing works
Serafin, A., Culebras, M., Oliveira, J. M., Koffler, J. Y., & Collins, M. N. (2023) · Advanced Composites and Hybrid Materials · doi:10.1007/s42114-023-00665-w · Cited by 79 · see citing works
3D printing of cell-laden visible light curable glycol chitosan bioink for bone tissue engineering
Chang, H. K., Yang, D. H., Ha, M. Y., Kim, H. J., Kim, C. H., Kim, S. H., Choi, J. W., & Chun, H. J. (2022) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2022.119328 · Cited by 78 · see citing works
Kozani, P. S., Kozani, P. S., Hamidi, M., Okoro, O. V., Eskandani, M., & Jaymand, M. (2021) · International Journal of Polymeric Materials · doi:10.1080/00914037.2021.1962876 · Cited by 77 · see citing works
Recent advances in bioprinting using silk protein-based bioinks
Chakraborty, J., Mu, X., Pramanick, A., Kaplan, D. L., & Ghosh, S. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121672 · Cited by 74 · see citing works
Jorgensen, A. M., Chou, Z., Gillispie, G. J., Lee, S. J., Yoo, J. J., Söker, S., & Atala, A. (2020) · Nanomaterials · doi:10.3390/nano10081484 · Cited by 74 · see citing works
Self-citationThe Influence of Printing Parameters and Cell Density on Bioink Printing Outcomes
Gillispie, G. J., Han, A., Uzun‐Per, M., Fisher, J. P., Mikos, A. G., Niazi, M. K. K., Yoo, J. J., Lee, S. J., & Atala, A. (2020) · Tissue Engineering Part A · doi:10.1089/ten.tea.2020.0210 · Cited by 73 · see citing works
Self-citationThe role of hydrocolloids on the 3D printability of meat products
Dick, A., Dong, X., Bhandari, B., & Prakash, S. (2021) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2021.106879 · Cited by 73 · see citing works
Chand, R., Muhire, B. S., & Vijayavenkataraman, S. (2022) · International Journal of Bioprinting · doi:10.18063/ijb.v8i2.545 · Cited by 73 · see citing works
Evans, S. E., Harrington, T. S., Rodríguez-Rivero, M. C., Rognin, E., Tuladhar, T. R., & Daly, R. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120443 · Cited by 71 · see citing works
3D printed colloidal biomaterials based on photo-reactive gelatin nanoparticles
Diba, M., Koons, G. L., Bedell, M. L., & Mikos, A. G. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120871 · Cited by 71 · see citing works
Self-citationKey parameters and applications of extrusion-based bioprinting
Tian, S., Zhao, H., & Lewinski, N. A. (2021) · Bioprinting · doi:10.1016/j.bprint.2021.e00156 · Cited by 70 · see citing works
Meniscus regeneration by 3D printing technologies: Current advances and future perspectives
Stocco, E., Porzionato, A., Rose, E. D., Barbon, S., De, R., & Macchi, V. (2022) · Journal of Tissue Engineering · doi:10.1177/20417314211065860 · Cited by 70 · see citing works
Kappa-Carrageenan-Based Dual Crosslinkable Bioink for Extrusion Type Bioprinting
Lim, W., Kim, G. J., Kim, H. W., Lee, J., Zhang, X., Kang, M. G., Seo, J. W., Cha, J. M., Park, H. J., Lee, M., et al. (2020) · Polymers · doi:10.3390/polym12102377 · Cited by 69 · see citing works
Granular hydrogels for 3D bioprinting applications
Cheng, W., Zhang, J., Liu, J., & Yu, Z. (2020) · Open Research (University of Surrey) · doi:10.1002/viw.20200060 · Cited by 69 · see citing works
Patient‐Specific Bone Particles Bioprinting for Bone Tissue Engineering
Ratheesh, G., Vaquette, C., & Xiao, Y. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.202001323 · Cited by 68 · see citing works
Masri, S., & Fauzi, M. B. (2021) · Polymers · doi:10.3390/polym13071011 · Cited by 67 · see citing works
Current Trends on Protein Driven Bioinks for 3D Printing
Veiga, A., Silva, I. V., Duarte, M. M., & Oliveira, A. L. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13091444 · Cited by 67 · see citing works
Jongprasitkul, H., Turunen, S., Parihar, V. S., & Kellomäki, M. (2021) · Bioprinting · doi:10.1016/j.bprint.2021.e00185 · Cited by 67 · see citing works
Li, J., Moeinzadeh, S., Kim, C., Pan, C., Weale, G., Kim, S., Abrams, G. D., James, A. W., Choo, H., Chan, C., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121969 · Cited by 66 · see citing works
Multilayer 3D bioprinting and complex mechanical properties of alginate-gelatin mesostructures
Soufivand, A. A., Faber, J., Hinrichsen, J., & Budday, S. (2023) · Scientific Reports · doi:10.1038/s41598-023-38323-2 · Cited by 66 · see citing works
3D scaffolds in the treatment of diabetic foot ulcers: New trends vs conventional approaches
Glover, K., Stratakos, A. C., Váradi, A., & Lamprou, D. A. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120423 · Cited by 65 · see citing works
3D bioprinting of molecularly engineered PEG-based hydrogels utilizing gelatin fragments
Piluso, S., Skvortsov, G. A., Altunbek, M., Afghah, F., Khani, N., Koç, B., & Patterson, J. (2021) · Biofabrication · doi:10.1088/1758-5090/ac0ff0 · Cited by 65 · see citing works
Nadernezhad, A., & Gröll, J. (2022) · Advanced Science · doi:10.1002/advs.202202638 · Cited by 65 · see citing works
3D Printing of Polysaccharide-Based Hydrogel Scaffolds for Tissue Engineering Applications: A Review
Tamo, A. K., Djouonkep, L. D. W., & Selabi, N. B. S. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.132123 · Cited by 70 · see citing works
Versatility on demand – The case for semi-solid micro-extrusion in pharmaceutics
Rahman, J., & Quodbach, J. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.02.013 · Cited by 64 · see citing works
Biomechanical factors in three-dimensional tissue bioprinting
Ning, L., Gil, C. J., Hwang, B., Theus, A. S., Perez, L., Tomov, M. L., Bauser‐Heaton, H. D., & Serpooshan, V. (2020) · Applied Physics Reviews · doi:10.1063/5.0023206 · Cited by 62 · see citing works
Advanced strategies in the application of gelatin-based bioink for extrusion bioprinting
Yang, J., He, H., Li, D., Zhang, Q., Xu, L., & Ruan, C. (2023) · Bio-Design and Manufacturing · doi:10.1007/s42242-023-00236-4 · Cited by 64 · see citing works
3D Printed Biocatalytic Living Materials with Dual‐Network Reinforced Bioinks
He, F., Ou, Y., Liu, J., Huang, Q. H., Tang, B., Xin, F., Zhang, J., Jiang, M., Chen, S., & Yu, Z. (2021) · Small · doi:10.1002/smll.202104820 · Cited by 61 · see citing works
Roche, C. D., Sharma, P., Ashton, A., Jackson, C. J., Xue, M., & Gentile, C. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.636257 · Cited by 60 · see citing works
Clinical challenges in bone tissue engineering - A narrative review
Hoveidaei, A. H., Sadat‐Shojai, M., Nabavizadeh, S. S., Niakan, R., Shirinezhad, A., Mosalamiaghili, S., & Tabaie, S. A. (2024) · Bone · doi:10.1016/j.bone.2024.117363 · Cited by 61 · see citing works
Cleymand, F., Poerio, A., Mamanov, A., Elkhoury, K., Ikhelf, L., Jehl, J.-P., Kahn, C. J. F., Ponçot, M., Arab‐Tehrany, E., & Mano, J. F. (2020) · Bioprinting · doi:10.1016/j.bprint.2020.e00122 · Cited by 56 · see citing works
Șufaru, I.-G., Macovei, G., Stoleriu, S., Mârțu, M.-A., Luchian, I. A., Kappenberg-Niţescu, D.-C., & Solomon, S. M. (2022) · Membranes · doi:10.3390/membranes12090902 · Cited by 55 · see citing works
Application of Hydrogels as Three-Dimensional Bioprinting Ink for Tissue Engineering
Xie, M., Su, J., Zhou, S., Li, J., & Zhang, K. (2023) · Gels · doi:10.3390/gels9020088 · Cited by 55 · see citing works
Preliminary Evaluation of 3D Printed Chitosan/Pectin Constructs for Biomedical Applications
Michailidou, G., Terzopoulou, Z. N., Kehagia, A., Michopoulou, A., & Bikiaris, D. Ν. (2021) · Marine Drugs · doi:10.3390/md19010036 · Cited by 55 · see citing works
A review on alginate-based bioinks, combination with other natural biomaterials and characteristics
Shams, E., Barzad, M. S., Mohamadnia, S., Tavakoli, O., & Mehrdadfar, A. (2022) · Journal of Biomaterials Applications · doi:10.1177/08853282221085690 · Cited by 54 · see citing works
Digital Light Processing 3D Bioprinting of Gelatin‐Norbornene Hydrogel for Enhanced Vascularization
Duong, V. T., & Lin, C. (2023) · Macromolecular Bioscience · doi:10.1002/mabi.202300213 · Cited by 54 · see citing works
Zhu, P., Chu, Y., Yang, J., & Chen, L. (2024) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2024.110391 · Cited by 54 · see citing works
Lee, H., Kim, W.-J., Lee, J., Park, K.-S., Yoo, J. J., Atala, A., Kim, G., & Lee, S. J. (2021) · Applied Physics Reviews · doi:10.1063/5.0039639 · Cited by 54 · see citing works
Self-citationSmart Bioinks for the Printing of Human Tissue Models
Maan, Z., Masri, N. Z., & Willerth, S. M. (2022) · Biomolecules · doi:10.3390/biom12010141 · Cited by 53 · see citing works
Shi, H., Li, Y., Xu, K., & Yin, J. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100799 · Cited by 52 · see citing works
Mierke, C. T. (2024) · Cells · doi:10.3390/cells13191638 · Cited by 54 · see citing works
Bedell, M. L., Torres, A. L., Hogan, K. J., Wang, Z., Wang, B., Melchiorri, A. J., Grande-Allen, K. J., & Mikos, A. G. (2022) · Biofabrication · doi:10.1088/1758-5090/ac8768 · Cited by 50 · see citing works
Self-citationBioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Perin, F., Ouyang, L., Lim, K. S., Motta, A., Maniglio, D., Moroni, L., & Mota, C. (2025) · Advanced Materials · doi:10.1002/adma.202504037 · Cited by 50 · see citing works
Click chemistry for 3D bioprinting
Nie, L., Sun, Y., Okoro, O. V., Deng, Y., Jiang, G., & Shavandi, A. (2023) · Materials Horizons · doi:10.1039/d3mh00516j · Cited by 48 · see citing works
Krishna, D. V., & Sankar, M. R. (2023) · Engineered Regeneration · doi:10.1016/j.engreg.2023.07.002 · Cited by 47 · see citing works
Machine Learning in Gel-Based Additive Manufacturing: From Material Design to Process Optimization
Zhang, Z., Wang, Y., & Wang, W. (2025) · Gels · doi:10.3390/gels11080582 · Cited by 52 · see citing works
A rheological approach to assess the printability of thermosensitive chitosan-based biomaterial inks
Rahimnejad, M., Labonté-Dupuis, T., Demarquette, N. R., & Lerouge, S. (2020) · Biomedical Materials · doi:10.1088/1748-605x/abb2d8 · Cited by 46 · see citing works
Tunable and Compartmentalized Multimaterial Bioprinting for Complex Living Tissue Constructs
Hassan, S., Gomez-Reyes, E., Enciso‐Martínez, E., Shi, K., Campos, J. G., Soria, O. Y. P., Ceron, E. L., Lee, M. C., García-Reyes, I. E., Steakelum, J., et al. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c12585 · Cited by 46 · see citing works
3D-Printed Hybrid Collagen/GelMA Hydrogels for Tissue Engineering Applications
Nagaraj, A., Etxabide, A., Naffa, R., Zidan, G., & Seyfoddin, A. (2022) · Biology · doi:10.3390/biology11111561 · Cited by 44 · see citing works
Computational Modeling and Experimental Characterization of Extrusion Printing into Suspension Baths
Prendergast, M. E., & Burdick, J. A. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202101679 · Cited by 44 · see citing works
Shape Fidelity Evaluation of Alginate-Based Hydrogels through Extrusion-Based Bioprinting
Temirel, M., Dabbagh, S. R., & Taşoğlu, S. (2022) · Journal of Functional Biomaterials · doi:10.3390/jfb13040225 · Cited by 43 · see citing works
Munoz-Perez, E., Perez‐Valle, A., Igartúa, M., Santos‐Vizcaíno, E., & Hernández, R. M. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213414 · Cited by 43 · see citing works
Design and 3D Printing of Personalized Hybrid and Gradient Structures for Critical Size Bone Defects
Altunbek, M., Afghah, F., Fallah, A., Acar, A. A., & Koç, B. (2023) · ACS Applied Bio Materials · doi:10.1021/acsabm.3c00107 · Cited by 43 · see citing works
Lightweight 3D bioprinting with point by point photocuring
Zhang, P., Wang, H., Wang, P., Zheng, Y., Liu, L., Hu, J. P., Liu, Y., Gao, Q., & He, Y. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.10.023 · Cited by 42 · see citing works
Bolívar‐Monsalve, E. J., Ceballos‐González, C. F., Chávez-Madero, C., de la Cruz‐Rivas, B. G., Velásquez‐Marín, S., Mora‐Godínez, S., Reyes‐Cortés, L. M., Khademhosseini, A., Weiss, P. S., Samandari, M., et al. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202200448 · Cited by 41 · see citing works
Intrinsically cryopreservable, bacteriostatic, durable glycerohydrogel inks for 3D bioprinting
Liu, M., Jiang, S., Witman, N., Wang, H., Wang, W., Fu, W., & You, Z. (2023) · Matter · doi:10.1016/j.matt.2022.12.013 · Cited by 41 · see citing works
Fibrinogen-Based Bioink for Application in Skin Equivalent 3D Bioprinting
Cavallo, A., Kayal, T. A., Mero, A., Mezzetta, A., Guazzelli, L., Soldani, G., & Losi, P. (2023) · Journal of Functional Biomaterials · doi:10.3390/jfb14090459 · Cited by 41 · see citing works
Karamchand, L., Makeiff, D., Gao, Y., Azyat, K., Serpe, M. J., & Kulka, M. (2022) · Bioprinting · doi:10.1016/j.bprint.2022.e00255 · Cited by 43 · see citing works
Coşkun, S., Akbulut, S. O., Sarıkaya, B., Çakmak, S., & Gümüşderelı́oğlu, M. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.09.078 · Cited by 40 · see citing works
Dai, Y., Wang, P., Mishra, A., You, K., Zong, Y., Lu, W. F., Chow, E. K., Preshaw, P. M., Huang, D., Chew, R. J. J., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202402727 · Cited by 43 · see citing works
Song, K., Ren, B., Zhai, Y., Chai, W., & Huang, Y. H. (2021) · Biofabrication · doi:10.1088/1758-5090/ac3d75 · Cited by 38 · see citing works
Teng, X.-X., Li, C.-L., Mujumdar, A., & Zhang, M. (2022) · Foods · doi:10.3390/foods11244111 · Cited by 33 · see citing works
Three-Dimensional Bioprinting of Organoids: Past, Present, and Prospective
Cabral, M., Cheng, K., & Zhu, D. (2024) · Tissue Engineering Part A · doi:10.1089/ten.tea.2023.0209 · Cited by 38 · see citing works
- Authors
- Gillispie, G., Prim, P., Copus, J., Fisher, J., Mikos, A. G., Yoo, J. J., Atala, A., & Lee, S. J.
- Affiliations
- Virginia Tech - Wake Forest University School of Biomedical Engineering & Sciences (US)
- Wake Forest University Health Sciences (US)
- University of Maryland, College Park (US)
- Rice University (US)
- Corresponding author
- Lee, Sang Jin
- ORCID
- Venue
- Biofabrication
- Publisher
- IOP Publishing
- Published
- 2020-02-19
- Volume
- 12
- Issue
- 2
- Pages
- 022003
- ISSN
- 1758-5082 (ISSN-L)
- 1758-5090
- PMC
- PMC7039534
- OpenAlex
- W3000783277
- Cited by
- 426
- References
- 93
- Citations by year
- 2026: 71 · 2025: 70 · 2024: 75 · 2023: 66 · 2022: 69 · 2021: 54 · 2020: 21
- FWCI
- 4.39
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Biofabrication (publishedVersion, other-oa)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Biomedical Imaging and Bioengineering (1P41EB023833-346 01)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Physical Sciences › Engineering › Automotive Engineering › Additive Manufacturing and 3D Printing Technologies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Keywords
- extrusion-based bioprinting, extrudability, shape fidelity, printing accuracy, tissue engineering scaffolds
- MeSH terms
- Animals, Humans, Tissue Engineering, Tissue Scaffolds, Bioprinting, Printing, Three-Dimensional
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
