The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
Antibody-Dependent Enhancement of Virus Infection and Disease
Abstract
In general, virus-specific antibodies are considered antiviral and play an important role in the control of virus infections in a number of ways. However, in some instances, the presence of specific antibodies can be beneficial to the virus. This activity is known as antibody-dependent enhancement (ADE) of virus infection. The ADE of virus infection is a phenomenon in which virus-specific antibodies enhance the entry of virus, and in some cases the replication of virus, into monocytes/macrophages and granulocytic cells through interaction with Fc and/or complement receptors. This phenomenon has been reported in vitro and in vivo for viruses representing numerous families and genera of public health and veterinary importance. These viruses share some common features such as preferential replication in macrophages, ability to establish persistence, and antigenic diversity. For some viruses, ADE of infection has become a great concern to disease control by vaccination. Consequently, numerous approaches have been made to the development of vaccines with minimum or no risk for ADE. Identification of viral epitopes associated with ADE or neutralization is important for this purpose. In addition, clear understanding of the cellular events after virus entry through ADE has become crucial for developing efficient intervention. However, the mechanisms of ADE still remain to be better understood.
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RESPIRATORY VIRUS IMMUNIZATION
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Cited by
Buchbinder, S. P., Mehrotra, D. V., Duerr, A., Fitzgerald, D. W., Mogg, R., Li, D., Gilbert, P. B., Lama, J. R., Marmor, M., del Rio, C., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61591-3 · Cited by 1,713
Casagrande, M., Favieri, F., Tambelli, R., & Forte, G. (2020) · Sleep Medicine · doi:10.1016/j.sleep.2020.05.011 · Cited by 735
Halstead, S. B., Mahalingam, S., Marovich, M. A., Ubol, S., & Mosser, D. M. (2010) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70166-3 · Cited by 409
Mechanism of action of mRNA-based vaccines
Iavarone, C., O’hagan, D. T., Yu, D., Delahaye, N. F., & Ulmer, J. B. (2017) · Expert Review of Vaccines · doi:10.1080/14760584.2017.1355245 · Cited by 234
Evaluation of modified vaccinia virus Ankara based recombinant SARS vaccine in ferrets
CZUB, M., WEINGARTL, H., CZUB, S., HE, R., & CAO, J. (2005) · Vaccine · doi:10.1016/j.vaccine.2005.01.033 · Cited by 180
Metadata
- Authors
- Tirado, S. M. C., & Yoon, K.-J.
- Venue
- Viral Immunology
- Publisher
- SAGE Publications
- Published
- 2003-04
- Volume
- 16
- Issue
- 1
- Pages
- 69-86
- ISSN
- 0882-8245 (ISSN-L)
- 1557-8976
- OpenAlex
- W2084534408
- Cited by
- 313
- References
- 77
- FWCI
- 4.40
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
