Apoptosis and Aging: Role of p66 Shc Redox Protein

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c-Jun N-terminal Kinase Specifically Phosphorylates p66ShcA at Serine 36 in Response to Ultraviolet Irradiation

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Molecular mechanisms underlying metabolic syndrome: the expanding role of the adipocyte

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Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways

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p66ShcA modulates oxidative stress and survival of endothelial progenitor cells in response to high glucose

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Inhibition of p66Shc-mediated mitochondrial apoptosis via targeting prolyl-isomerase Pin1 attenuates intestinal ischemia/reperfusion injury in rats

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Role of MnSOD and p66shc in Mitochondrial Response to p53

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Regulatory effects of the mitochondrial energetic status on mitochondrial p66Shc

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p66^<i>Shc</i>Deletion Confers Vascular Protection in Advanced Atherosclerosis in Hypercholesterolemic Apolipoprotein E Knockout Mice

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Balancing Mitochondrial Redox Signaling: A Key Point in Metabolic Regulation

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Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice

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p66Shc, Mitochondria, and the Generation of Reactive Oxygen Species

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Long noncoding RNA MAGI2-AS3 regulates the H2O2 level and cell senescence via HSPA8

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p66Shc—a longevity redox protein in human prostate cancer progression and metastasis

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The P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration

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Oxidative Stress in Benign Prostatic Hyperplasia: Mechanisms, Clinical Relevance and Therapeutic Perspectives

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The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells

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Perturbations in mitochondrial dynamics by p66Shc lead to renal tubular oxidative injury in human diabetic nephropathy

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Decreased p66Shc promoter methylation in patients with end-stage renal disease

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Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene

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The mitochondrial PKCδ/retinol signal complex exerts real-time control on energy homeostasis

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Cellular Signal Transduction Pathways Involved in Acute Lung Injury Induced by Intestinal Ischemia‐Reperfusion

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The p66Shc Adaptor Protein Controls Oxidative Stress Response in Early Bovine Embryos

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Retinol as electron carrier in redox signaling, a new frontier in vitamin A research.

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Oxidative Stress: A Possible Trigger for Pelvic Organ Prolapse

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p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans

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Blockade of PKCβ protects against remote organ injury induced by intestinal ischemia and reperfusion via a p66shc-mediated mitochondrial apoptotic pathway

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p66shc siRNA-Encapsulated PLGA Nanoparticles Ameliorate Neuropathic Pain Following Spinal Nerve Ligation

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The redox protein p66shc mediates cochlear vascular dysfunction and transient noise-induced hearing loss

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Alternative Mechanisms of p53 Action During the Unfolded Protein Response

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Redox Imbalance as a Common Pathogenic Factor Linking Hearing Loss and Cognitive Decline

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Diallyl trisulfide-induced prostate cancer cell death is associated with Akt/PKB dephosphorylation mediated by P-p66shc

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IGF-I stimulates reactive oxygen species (ROS) production and inhibits insulin-dependent glucose uptake via ROS in 3T3-L1 adipocytes

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p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy

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Propofol Protects Against High Glucose–Induced Endothelial Apoptosis and Dysfunction in Human Umbilical Vein Endothelial Cells

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Resveratrol regulates p66Shc activation in HaCaT cells

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The PKCβ-p66shc-NADPH oxidase pathway plays a crucial role in diabetic nephropathy

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Epidermal growth factor receptor and integrins meet redox signaling through P66shc and Rac1

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Propofol inhibits high glucose-induced PP2A expression in human umbilical vein endothelial cells

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Age-related subproteomic analysis of mouse liver and kidney peroxisomes

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Modelling the p53/p66Shc Aging Pathway in the Shortest Living Vertebrate Nothobranchius Furzeri

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Epigenetic enhancement of p66Shc during cellular replicative or premature senescence

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SIRT1 promotes pulmonary artery endothelial cell proliferation by targeting the Akt signaling pathway

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Overexpression of the elongation factor 1A1 relates to muscle proteolysis and proapoptotic p66(ShcA) gene transcription in hypercatabolic trauma patients

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Fluoride-Induced Mitochondrial Dysfunction and Approaches for Its Intervention

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Reactive Oxygen Species in the Induction of Toxicity

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Chromium III Histidinate Exposure Modulates Gene Expression in HaCaT Human Keratinocytes Exposed to Oxidative Stress

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P66Shc: A Pleiotropic Regulator of B Cell Trafficking and a Gatekeeper in Chronic Lymphocytic Leukemia

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P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan

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Vitamin A as PKC Co-factor and Regulator of Mitochondrial Energetics

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P66Shc Deletion Ameliorates Oxidative Stress and Cardiac Dysfunction in Pressure Overload-Induced Heart Failure

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Cytoplasmic signaling in the control of mitochondrial uproar?

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The p66Shc adapter protein regulates the morphogenesis and epithelial maturation of fetal mouse lungs

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ShcC proteins: Brain aging and beyond

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Genetics, Redox Signaling, Oxidative Stress, and Apoptosis in Mammalian Aging

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Deletion of p66 S hc in mice increases the frequency of size‐change mutations in the lac Z transgene

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Efeito do chá verde (Camelia sinensis) em ratos com obesidade induzida por dieta hipercalórica

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The Influence of Shc Proteins and Aging on Whole Body Energy Expenditure and Substrate Utilization in Mice

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β-caryophyllene regulates H3K36me3 to inhibit conidial germination and mycelial growth of Fusarium proliferatum

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Propofol attenuates high glucose‐induced superoxide anion accumulation in human umbilical vein endothelial cells

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Elevated p66Shc is associated with intracellular redox imbalance in developmentally compromised bovine embryos

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Phosphorylation of p66shc mediates 6-hydroxydopamine cytotoxicity

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Simultaneous Analysis of Expression of Multiple Redox-Sensitive and Apoptotic Genes in Hypothalamic Neurons Exposed to Cholesterol Secoaldehyde

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The Role of p66shc in Oxidative Stress and Apoptosis

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p66Shc aging protein in control of fibroblasts cell fate

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p66Shc: at the crossroad of oxidative stress and the genetics of aging

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Apoptosis and Oxidative Stress-Related Diseases: The p66Shc Connection

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