Selenium and the Selenoprotein Thioredoxin Reductase in the Prevention, Treatment and Diagnostics of Cancer

Effects of Selenium Supplementation for Cancer Prevention in Patients With Carcinoma of the Skin

Clark, L. (1996) · JAMA · doi:10.1001/jama.276.24.1957 · Cited by 2,988

Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

Saitoh, M., Nishitoh, H., Fujii, M., Takeda, K., Tobiume, K., Sawada, Y., Kawabata, M., Miyazono, K., & Ichijo, H. (1998) · The EMBO Journal · doi:10.1093/emboj/17.9.2596 · Cited by 2,377

Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers

Lippman, S. M., Klein, E. A., Goodman, P. J., Lucia, M. S., Thompson, I. M., Ford, L. G., Parnes, H. L., Minasian, L. M., Gaziano, J. M., Hartline, J. A., et al. (2008) · JAMA · doi:10.1001/jama.2008.864 · Cited by 2,164

From Selenium to Selenoproteins: Synthesis, Identity, and Their Role in Human Health

Papp, L. V., Lu, J., Holmgren, A., & Khanna, K. K. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1528 · Cited by 1,357

Glutathione in Cancer Biology and Therapy

Estrela, J. M., Ortega, A., & Obrador, E. (2006) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408360500523878 · Cited by 1,041

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

Shih, A. Y., Johnson, D. A., Wong, G., Kraft, A. D., Jiang, L., Erb, H., Johnson, J. A., & Murphy, T. H. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03394.2003 · Cited by 792

Rho GTPases are over-expressed in human tumors

Fritz, G., Just, I., & Kaina, B. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19990531)81:5 · Cited by 671

Chemopreventive Agents

Combs, G. F., & Gray, W. P. (1998) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(98)00014-x · Cited by 667

Aberrant and Alternative Splicing in Cancer

Venables, J. P. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-1910 · Cited by 644

Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis

Bjelaković, G., Nikolova, D., Simonetti, R. G., & Gluud, C. N. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17138-9 · Cited by 619

Selenium and its relationship to cancer: an update

Whanger, P. D. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20031015 · Cited by 615

The thioredoxin system in cancer

Arnér, E. S. J., & Holmgren, A. (2006) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2006.10.009 · Cited by 589

PREDIAGNOSTIC SERUM SELENIUM AND RISK OF CANCER

Willett, W., Morris, J. S., Pressel, S., Taylor, J., Polk, B. F., Stampfer, M., ROSNER, B. A., Schneider, K. A., & Hames, C. G. (1983) · The Lancet · doi:10.1016/s0140-6736(83)90116-2 · Cited by 548

Human Placenta Thioredoxin Reductase

Gromer, S., Arscott, L. D., Williams, C. H., Schirmer, R. H., & Becker, K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.32.20096 · Cited by 538

Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide

Lu, J., Chew, E.-H., & Holmgren, A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701549104 · Cited by 526

Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial

Duffield‐Lillico, A. J., Dalkin, B. L., Reid, M. E., Turnbull, B. W., Slate, E. H., Jacobs, E. T., Marshall, J. R., Clark, L. C., & for the Nutritional Prevention of Cancer Study Group (2003) · British Journal of Urology · doi:10.1046/j.1464-410x.2003.04167.x · Cited by 514

Cancer mortality correlation studies-III: Statistical associations with dietary selenium intakes

Schrauzer, G. N., White, D. A., & Schneider, C. J. (1977) · Bioinorganic Chemistry · doi:10.1016/s0006-3061(00)80126-x · Cited by 491

The thioredoxin system—From science to clinic

Gromer, S., Urig, S., & Becker, K. (2003) · Medicinal Research Reviews · doi:10.1002/med.10051 · Cited by 482

The role of the redox protein thioredoxin in cell growth and cancer

Powis, G., Mustacich, D. J., & Coon, A. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00313-0 · Cited by 442

Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells

Marzano, C., Gandin, V., Folda, A., Scutari, G., Bindoli, A., & Rigobello, M. P. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.12.021 · Cited by 420

Thioredoxin reductase as a pathophysiological factor and drug target

Becker, K., Gromer, S., Schirmer, R. H., & Müller, S. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01703.x · Cited by 389

The Chemistry and Toxicity of Selenium Compounds, with Special Reference to the Selenium Problem.

Painter, E. P. (1941) · Chemical Reviews · doi:10.1021/cr60090a001 · Cited by 371

Reduction of the selenotrisulfide derivative of glutathione to a persulfide analog by gluthathione reductase

Ganther, H. E. (1971) · Biochemistry · doi:10.1021/bi00798a013 · Cited by 357

Cancer-associated regulation of alternative splicing

Venables, J. P., Klinck, R., Koh, C., Gervais-Bird, J., Bramard, A., Inkel, L., Durand, M., Couture, S., Froehlich, U., Lapointe, E., et al. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1608 · Cited by 355

The connection between splicing and cancer

Srebrow, A., & Kornblihtt, A. R. (2006) · Journal of Cell Science · doi:10.1242/jcs.03053 · Cited by 343

On the potential of thioredoxin reductase inhibitors for cancer therapy

Urig, S., & Becker, K. (2006) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2006.09.004 · Cited by 338

The thioredoxin-thioredoxin reductase system: over-expression in human cancer.

Lincoln, D. T., Emadi, E. M. A., Tonissen, K. F., & Clarke, F. M. (2003) · PubMed · Cited by 337

Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols

Björnstedt, M., Hámberg, M., Kumar, S., Xue, J., & Holmgren, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.20.11761 · Cited by 312

Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia.

Berggren, M. I., Gallegos, A. C., Gasdaska, J. R., Gasdaska, P. Y., Warneke, J. A., & Powis, G. (1996) · PubMed · Cited by 306

Unbalanced alternative splicing and its significance in cancer

Venables, J. P. (2006) · BioEssays · doi:10.1002/bies.20390 · Cited by 304

Selenium compounds have disparate abilities to impose oxidative stress and induce apoptosis

Stewart, M. S., Spallholz, J. E., Neldner, K. H., & Pence, B. C. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00147-6 · Cited by 294

Selenomethionine regulation of p53 by a ref1-dependent redox mechanism

Seo, Y. R., Kelley, M. R., & Smith, M. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.212319799 · Cited by 284

Thioredoxin Reductase 1 Deficiency Reverses Tumor Phenotype and Tumorigenicity of Lung Carcinoma Cells

Yoo, M., Xu, X., Carlson, B. A., Gladyshev, V. N., & Hatfield, D. L. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.c600012200 · Cited by 269

Alternative splicing: an emerging topic in molecular and clinical oncology

Pajares, M. J., Ezponda, T., Catena, R., Calvo, A., Pı́o, R., & Montuenga, L. M. (2007) · The Lancet Oncology · doi:10.1016/s1470-2045(07)70104-3 · Cited by 268

Thioredoxin signaling as a target for cancer therapy

Powis, G., & Kirkpatrick, D. L. (2007) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2007.04.003 · Cited by 265

Splice variants as cancer biomarkers

Brinkman, B. M. N. (2004) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2004.05.015 · Cited by 262

Selenium Distribution and Human Cancer Mortality

Shamberger, R. J., & Willis, C. E. (1971) · CRC Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408367109151308 · Cited by 261

Sodium Selenite Induces Superoxide-Mediated Mitochondrial Damage and Subsequent Autophagic Cell Death in Malignant Glioma Cells

Kim, E. H., Sohn, S., Kwon, H. J., Kim, S. U., Kim, M.-J., Lee, S.-J., & Choi, K. S. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-4217 · Cited by 251

Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non‐stoichiometric oxidation of NADPH in the presence of oxygen

Kumar, S., Björnstedt, M., & Holmgren, A. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb17068.x · Cited by 248

The thioredoxin reductase/thioredoxin system: Novel redox targets for cancer therapy

Biaglow, J. E., & Miller, R. A. (2005) · Cancer Biology & Therapy · doi:10.4161/cbt.4.1.1434 · Cited by 245

Alternative Splicing in Colon, Bladder, and Prostate Cancer Identified by Exon Array Analysis

Thorsen, K., Sørensen, K. D., Brems-Eskildsen, A. S., Modin, C., Gaustadnes, M., Hein, A.-M. K., Kruhøffer, M., Laurberg, S., Borre, M., Wang, K., et al. (2008) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m700590-mcp200 · Cited by 245

Selenium is an essential trace nutrient for growth of WI-38 diploid human fibroblasts.

McKeehan, W. L., Hamilton, W. G., & Ham, R. G. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.6.2023 · Cited by 244

Methylarsenicals and Arsinothiols Are Potent Inhibitors of Mouse Liver Thioredoxin Reductase

Lin, S., Cullen, W. R., & Thomas, D. J. (1999) · Chemical Research in Toxicology · doi:10.1021/tx9900775 · Cited by 230

A report of high-dose selenium supplementation: response and toxicities

Reid, M. E., Stratton, M. S., Duffield‐Lillico, A. J., Fakih, M., Natarajan, R., Clark, L. C., & Marshall, J. R. (2004) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2004.03.004 · Cited by 225

Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds

Witte, A.-B., Anestål, K., Jerremalm, E., Ehrsson, H., & Arnér, E. S. J. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.04.025 · Cited by 225

Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase.

Björnstedt, M., Kumar, S., & Holmgren, A. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42403-9 · Cited by 211

Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: Role of NF‐E2‐related factor‐2

Sakurai, A., Nishimoto, M., Himeno, S., Imura, N., Tsujimoto, M., Kunimoto, M., & Hara, S. (2004) · Journal of Cellular Physiology · doi:10.1002/jcp.20246 · Cited by 210

The Mammalian Cytosolic Selenoenzyme Thioredoxin Reductase Reduces Ubiquinone

Xia, L., Nordman, T., Olsson, J. M., Damdimopoulos, A. E., Björkhem‐Bergman, L., Nalvarte, I., Eriksson, L. C., Arnér, E. S. J., Spyrou, G., & Björnstedt, M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210456200 · Cited by 209

Selenoproteins and human health: Insights from epidemiological data

Rayman, M. P. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.03.014 · Cited by 199

Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells

Lin, Y., & Spallholz, J. E. (1993) · Biochemical Pharmacology · doi:10.1016/0006-2952(93)90080-g · Cited by 196

Widespread expression of thioredoxin and thioredoxin reductase in non-small cell lung carcinoma.

Soini, Y., Kahlos, K., Näpänkangas, U., Kaarteenaho–Wiik, R., Säily, M., Koistinen, P., Pääakkö, P., Holmgren, A., & Kinnula, V. L. (2001) · PubMed · Cited by 188

Selenium and immune responses

Kiremidjian-Schumacher, L., & Stotzky, G. (1987) · Environmental Research · doi:10.1016/s0013-9351(87)80194-9 · Cited by 187

Alternative Splicing and Tumor Progression

Ghigna, C., Valacca, C., & Biamonti, G. (2008) · Current Genomics · doi:10.2174/138920208786847971 · Cited by 187

Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences

Xu, Q. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg786 · Cited by 183

Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex

Arnér, E. S. J., Nakamura, H., Sasada, T., Yodoi, J., Holmgren, A., & Spyrou, G. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00698-0 · Cited by 178

Thioredoxin reductase as a novel molecular target for cancer therapy

Nguyen, P., Awwad, R. T., Smart, D. D., Spitz, D. R., & Gius, D. R. (2005) · Cancer Letters · doi:10.1016/j.canlet.2005.04.028 · Cited by 175

Extracellular thiol-assisted selenium uptake dependent on the x c − cystine transporter explains the cancer-specific cytotoxicity of selenite

Olm, E., Fernandes, A. P., Hebert, C., Rundlöf, A.-K., Larsen, E. H., Danielsson, O., & Björnstedt, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902204106 · Cited by 174

Catalytic Oxidation of Glutathione and Other Sulfhydryl Compounds by Selenite

Tsen, C. C., & Tappel, A. L. (1958) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77374-8 · Cited by 171

Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells.

Jiang, C., Wang, Z., Ganther, H. E., & Lü, J. (2002) · PubMed · Cited by 167

Motexafin Gadolinium, a Tumor-selective Drug Targeting Thioredoxin Reductase and Ribonucleotide Reductase

Hashemy, S. I., Ungerstedt, J. S., Avval, F. Z., & Holmgren, A. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511373200 · Cited by 164

Electrophilic Prostaglandins and Lipid Aldehydes Repress Redox-sensitive Transcription Factors p53 and Hypoxia-inducible Factor by Impairing the Selenoprotein Thioredoxin Reductase

Moos, P. J., Edes, K., Cassidy, P., Massuda, E., & Fitzpatrick, F. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211134200 · Cited by 162

Arsenicals Inhibit Thioredoxin Reductase in Cultured Rat Hepatocytes

Lin, S., Razo, L. M. D., Stýblo, M., Wang, C., Cullen, W., & Thomas, D. J. (2001) · Chemical Research in Toxicology · doi:10.1021/tx0001878 · Cited by 162

Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione

Ren, X., Bjoernstedt, M., Shen, B., Ericson, M. L., & Holmgren, A. (1993) · Biochemistry · doi:10.1021/bi00088a023 · Cited by 160

Inhibition of NF-κB DNA binding and nitric oxide induction in human T cells and lung adenocarcinoma cells by selenite treatment

Kim, I. Y., & Stadtman, T. C. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.12904 · Cited by 155

Ser326Cys polymorphism inhOGG1 gene and risk of esophageal cancer in a Chinese population

Xing, D.-Y., Tan, W., Song, N., & Lin, D. (2001) · International Journal of Cancer · doi:10.1002/1097-0215(20010520)95:3 · Cited by 153

Human Thioredoxin Reductase Is Efficiently Inhibited by (2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes. Possible Implications for a Novel Antitumor Strategy

Becker, K., Herold‐Mende, C. C., Park, J. J., Lowe, G. M., & Schirmer, R. H. (2001) · Journal of Medicinal Chemistry · doi:10.1021/jm001014i · Cited by 150

Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy

Sieja, K., & Talerczyk, M. (2004) · Gynecologic Oncology · doi:10.1016/j.ygyno.2003.12.013 · Cited by 150

Selenium and the thioredoxin and glutaredoxin systems.

Björnstedt, M., Kumar, S., Björkhem, L., Spyrou, G. P., & Holmgren, A. (1997) · PubMed · Cited by 149

Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c.

Rigobello, M., Scutari, G., Folda, A., & Bindoli, A. (2004) · Biochemical Pharmacology · doi:10.1016/j.bcp.2003.09.038 · Cited by 148

Extracellular Production of Hydrogen Selenide Accounts for Thiol-assisted Toxicity of Selenite against Saccharomyces cerevisiae

Tarze, A., Dauplais, M., Grigoras, I., Lazard, M., Duong, N.-T. H., Bessueille-Barbier, F., Blanquet, S., & Plateau, P. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m610078200 · Cited by 147

Selenite induces apoptosis in sarcomatoid malignant mesothelioma cells through oxidative stress

Nilsonne, G., Sun, X., Nyström, C., Rundlöf, A.-K., Fernandes, A. P., Björnstedt, M., & Dobra, K. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.04.031 · Cited by 138

Mechanism of Dithiocarbamate Inhibition of Apoptosis: Thiol Oxidation by Dithiocarbamate Disulfides Directly Inhibits Processing of the Caspase-3 Proenzyme

Nobel, S., Burgess, D. H., Zhivotovsky, B., Burkitt, M. J., Orrenius, S., & Slater, A. F. G. (1997) · Chemical Research in Toxicology · doi:10.1021/tx970006a · Cited by 132

The selenium metabolite selenodiglutathione induces p53 and apoptosis: relevance to the chemopreventive effects of selenium?

Lanfear, J., Fleming, J., Wu, L. L., Webster, G., & Harrison, P. R. (1994) · Carcinogenesis · doi:10.1093/carcin/15.7.1387 · Cited by 129

Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1)

Omata, Y., Folan, M., Shaw, M., Messer, R. L. W., Lockwood, P. E., Hobbs, D. T., Bouillaguet, S., Sano, H., Lewis, J. B., & Wataha, J. C. (2006) · Toxicology in Vitro · doi:10.1016/j.tiv.2006.01.012 · Cited by 129

Targeting Thioredoxin Reductase 1 Reduction in Cancer Cells Inhibits Self-Sufficient Growth and DNA Replication

Yoo, M., Xu, X.-M., Carlson, B. A., Patterson, A. D., Gladyshev, V. N., & Hatfield, D. L. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001112 · Cited by 128

Thioredoxin Reductase in Human Hepatoma Cells Is Transcriptionally Regulated by Sulforaphane and Other Electrophiles via an Antioxidant Response Element

Hintze, K. J., Wald, K., Zeng, H., Jeffery, E. H., & Finley, J. W. (2003) · Journal of Nutrition · doi:10.1093/jn/133.9.2721 · Cited by 128

Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation

Fiala, E. S. (1998) · Carcinogenesis · doi:10.1093/carcin/19.4.597 · Cited by 124

The protective role of selenium on the toxicity of cisplatin-contained chemotherapy regimen in cancer patients

Hu, J., Chen, Y., Zhang, Y., Zhou, M., Song, X., Zhang, B., Luo, L., Xu, P.-M., Zhao, Y.-N., Zhao, Y., et al. (1997) · Biological Trace Element Research · doi:10.1007/bf02785304 · Cited by 123

Dual role of glutathione in selenite-induced oxidative stress and apoptosis in human hepatoma cells

Shen, H. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00206-9 · Cited by 123

Selenotrisulfides. II. Cross-linking of reduced pancreatic ribonuclease with selenium

Ganther, H. E., & Corcoran, C. (1969) · Biochemistry · doi:10.1021/bi00834a044 · Cited by 123

Studies of safe maximal daily dietary selenium intake in a seleniferous area in China. I. Selenium intake and tissue selenium levels of the inhabitants.

Yang, G.-H., Zhou, R., Yin, S. N., Gu, L., Yan, B., Liu, Y., Liu, Y., & Li, X. (1989) · PubMed · Cited by 122

Supplementation of healthy volunteers with nutritionally relevant amounts of selenium increases the expression of lymphocyte protein biosynthesis genes

Pagmantidis, V., Méplan, C., van Schothorst, E. M., Keijer, J., & Hesketh, J. E. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.1.181 · Cited by 121

Contrasting Patterns of Regulation of the Antioxidant Selenoproteins, Thioredoxin Reductase, and Glutathione Peroxidase, in Cancer Cells

Gladyshev, V. N., Factor, V. M., Housseau, F., & Hatfield, D. L. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9495 · Cited by 121

Selenite Inhibits the c-Jun N-terminal Kinase/Stress-activated Protein Kinase (JNK/SAPK) through a Thiol Redox Mechanism

Park, H.-S., Park, E., Kim, M.-S., Ahn, K., Kim, I. Y., & Choi, E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.4.2527 · Cited by 119

Superoxide radical–initiated apoptotic signalling pathway in selenite-treated HepG2 cells: mitochondria serve as the main target

Shen, H.-M., Yang, C.-F., Ding, W.-X., Liu, J., & Ong, C.-N. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00421-4 · Cited by 119

Methyl-Selenium Compounds Inhibit Prostate Carcinogenesis in the Transgenic Adenocarcinoma of Mouse Prostate Model with Survival Benefit

Wang, L., Bonorden, M. J. L., Li, G., Lee, H., Hu, H., Zhang, Y., Liao, J. D., Cleary, M. P., & Lü, J. (2009) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-08-0173 · Cited by 118

Chemical Forms of Selenium in Rat Tissues after Administration of Selenite or Selenomethionine

Beilstein, M. A., & Whanger, P. D. (1986) · Journal of Nutrition · doi:10.1093/jn/116.9.1711 · Cited by 115

Dimethyldiselenide and Methylseleninic Acid Generate Superoxide in an In Vitro Chemiluminescence Assay in the Presence of Glutathione: Implications for the Anticarcinogenic Activity of L-Selenomethionine and L-Se-Methylselenocysteine

Spallholz, J. E., Shriver, B. J., & Reid, T. W. (2001) · Nutrition and Cancer · doi:10.1207/s15327914nc401_8 · Cited by 115

Se-Methylselenocysteine induces apoptosis through caspase activation in HL-60 cells

Kim, T., Jung, U., Cho, D.-Y., & Chung, A. (2001) · Carcinogenesis · doi:10.1093/carcin/22.4.559 · Cited by 111

Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells

Li, G., Hu, H., Jiang, C., Schuster, T. F., & Lü, J. (2007) · International Journal of Cancer · doi:10.1002/ijc.22480 · Cited by 110

Speciation and Bioavailability of Selenium in Yeast-Based Intervention Agents Used in Cancer Chemoprevention Studies

Larsen, E. H., Hansen, M., Paulin, H., Moesgaard, S., Reid, M. E., & Rayman, M. P. (2004) · Journal of AOAC International · doi:10.1093/jaoac/87.1.225 · Cited by 106

Expression of p53 Enhances Selenite-Induced Superoxide Production and Apoptosis in Human Prostate Cancer Cells

Zhao, R., Xiang, N., Domann, F. E., & Zhong, W. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-2216 · Cited by 106

Induction of the mitochondrial permeability transition by selenium compounds mediated by oxidation of the protein thiol groups and generation of the superoxide

Kim, T. S., Yun, B. Y., & Kim, I. Y. (2003) · Biochemical Pharmacology · doi:10.1016/j.bcp.2003.08.021 · Cited by 105

Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway

Hu, H., Jiang, C., Schuster, T. F., Li, G.-X., Daniel, P. T., & Lü, J. (2006) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0063 · Cited by 103

Effects of selenium and zinc supplementation on nutritional status in patients with cancer of digestive tract

Federico, A., Iodice, P., Federico, P., Rio, A. D., Mellone, M., Catalano, G., & Federico, P. (2001) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601157 · Cited by 101

Evidence for intriguingly complex transcription of human thioredoxin reductase 1

Rundlöf, A.-K., Janard, M., Miranda‐Vizuete, A., & Arnér, E. S. J. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.12.004 · Cited by 99

Selenium in the treatment of radiation-associated secondary lymphedema

Micke, O., Bruns, F., Mücke, R., Schäfer, U., Glatzel, M., DeVries, A., Schönekaes, K., Kisters, K., & Büntzel, J. (2003) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(02)04390-0 · Cited by 98

AP‐1 DNA‐binding activity is inhibited by selenite and selenodiglutathione

Spyrou, G., Björnstedt, M., Kumar, S., & Holmgren, A. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)00599-5 · Cited by 96

Selenium activates p53 and p38 pathways and induces caspase-independent cell death in cervical cancer cells

Rudolf, E., Rudolf, K., & Červinka, M. (2007) · Cell Biology and Toxicology · doi:10.1007/s10565-007-9022-1 · Cited by 95

A Global View of Cancer-Specific Transcript Variants by Subtractive Transcriptome-Wide Analysis

He, C., Zhou, F., Zuo, Z., Cheng, H., & Zhou, R. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004732 · Cited by 92

Methylation and demethylation of intermediates selenide and methylselenol in the metabolism of selenium

Ohta, Y., & Suzuki, K. T. (2007) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2007.09.011 · Cited by 91

The Core Promoter of Human Thioredoxin Reductase 1

Rundlöf, A.-K., Carlsten, M., & Arnér, E. S. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101452200 · Cited by 91

Tumor-selective killing by selenite in patient-matched pairs of normal and malignant prostate cells

Husbeck, B., Nonn, L., Peehl, D. M., & Knox, S. J. (2005) · The Prostate · doi:10.1002/pros.20337 · Cited by 90

Selenocysteine β-lyase and methylselenol demethylase in the metabolism of Se-methylated selenocompounds into selenide

Suzuki, K. T., Kurasaki, K., & Suzuki, N. (2007) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2007.03.007 · Cited by 88

Evolutionarily conserved and diverged alternative splicing events show different expression and functional profiles

Kan, Z. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki834 · Cited by 86

Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation

Fernandes, A. P., Capitanio, A., Selenius, M., Brodin, O., Rundlöf, A.-K., & Björnstedt, M. (2009) · Histopathology · doi:10.1111/j.1365-2559.2009.03381.x · Cited by 81

Reduction of Methionine Selenoxide to Selenomethionine by Glutathione

Assmann, A., Briviba, K., & Sies, H. (1998) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.0462 · Cited by 79

Drug-resistant human lung cancer cells are more sensitive to selenium cytotoxicity

Björkhem‐Bergman, L., Jönsson, K., Eriksson, L. C., Olsson, J. M., Lehmann, S., Paul, C., & Björnstedt, M. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)00981-4 · Cited by 77

Selenium prevents tumor development in a rat model for chemical carcinogenesis

Björkhem‐Bergman, L. (2004) · Carcinogenesis · doi:10.1093/carcin/bgh290 · Cited by 77

Studies on Analogues of L-Cysteine and L-Cystine

Weisberger, A. S., & Suhrland, L. G. (1956) · Blood · doi:10.1182/blood.v11.1.19.19 · Cited by 77

Selenite and selenate inhibit human lymphocyte growth via different mechanisms.

Spyrou, G. P., Björnstedt, M., Skog, S., & Holmgren, A. (1996) · PubMed · Cited by 75

Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift

Rigobello, M. P., Gandin, V., Folda, A., Rundlöf, A.-K., Fernandes, A. P., Bindoli, A., Marzano, C., & Björnstedt, M. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.05.027 · Cited by 75

Influence of Dietary Methionine on the Metabolism of Selenomethionine in Rats

Butler, J. A., Beilstein, M. A., & Whanger, P. D. (1989) · Journal of Nutrition · doi:10.1093/jn/119.7.1001 · Cited by 71

[22] Selenite and selenodiglutathione: Reactions with thioredoxin systems

Jornstedt, M. B., Kumar, S., & Holmgren, A. (1995) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(95)52024-4 · Cited by 70

Selenite Negatively Regulates Caspase-3 through a Redox Mechanism

Park, H.-S., Huh, S.-H., Kim, Y., Shim, J., Lee, S. H., Park, I., Jung, Y., Kim, I. Y., & Choi, E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.12.8487 · Cited by 69

Expression of Antioxidant Enzymes in Astrocytic Brain Tumors

Haapasalo, H. K., Kyläniemi, M., Paunu, N., Kinnula, V. L., & Soini, Y. (2003) · Brain Pathology · doi:10.1111/j.1750-3639.2003.tb00015.x · Cited by 69

Selenite (75Se) as a tumor-localizing agent in man.

Cavalieri, R. R., Scott, K. G., & Sairenji, E. (1966) · PubMed · Cited by 68

Identification of alternatively spliced mRNA variants related to cancers by genome-wide ESTs alignment

Hui, L., Zhang, X., Wu, X., Lin, Z., Wang, Q., Li, Y., & Hu, G. (2004) · Oncogene · doi:10.1038/sj.onc.1207362 · Cited by 68

Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia

Talbot, S. R., Nelson, R., & Self, W. T. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.161 · Cited by 68

Selenium in the Treatment of Head and Neck Lymphedema

Bruns, F., Büntzel, J., Mücke, R., Schönekaes, K., Kisters, K., & Micke, O. (2004) · Medical Principles and Practice · doi:10.1159/000078313 · Cited by 68

Reduction of Postoperative Lymphedema after Oral Tumor Surgery with Sodium Selenite

Zimmermann, T. P., Leonhardt, H., Kersting, S., Albrecht, S., Range, U., & Eckelt, U. (2005) · Biological Trace Element Research · doi:10.1385/bter:106:3:193 · Cited by 62

The 58 kDa mouse selenoprotein is a BCNU‐sensitive thioredoxin reductase

Gromer, S., Schirmer, R. H., & Becker, K. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)00816-8 · Cited by 62

EID3 is a novel EID family member and an inhibitor of CBP-dependent co-activation

Båvner, A. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki667 · Cited by 61

Selenite-induced apoptosis of osteoclasts mediated by the mitochondrial pathway.

Chung, Y., Kim, T. S., Lee, S.-Y., Lee, S.-H., Choi, Y., Kim, N., Min, B.-M., Jeong, D., & Kim, I. (2006) · Toxicology Letters · doi:10.1016/j.toxlet.2005.06.019 · Cited by 60

Selenite-induced apoptosis in doxorubicin-resistant cells and effects on the thioredoxin system

Jönsson‐Videsäter, K., Björkhem‐Bergman, L., Hossain, A., Söderberg, A., Eriksson, L. C., Paul, C., Rosén, A., & Björnstedt, M. (2003) · Biochemical Pharmacology · doi:10.1016/j.bcp.2003.09.021 · Cited by 60

Integrating Metabolomics and Transcriptomics for Probing Se Anticancer Mechanisms

Fan, T. W. ‐., Higashi, R. M., & Lane, A. N. (2006) · Drug Metabolism Reviews · doi:10.1080/03602530600959599 · Cited by 55

Analysis of Methionine/Selenomethionine Oxidation and Methionine Sulfoxide Reductase Function Using Methionine-Rich Proteins and Antibodies against Their Oxidized Forms

Le, D. T., Liang, X., Fomenko, D. E., Raza, A. S., Chong, C., Carlson, B. A., Hatfield, D. L., & Gladyshev, V. N. (2008) · Biochemistry · doi:10.1021/bi800422s · Cited by 54

Selenite Incubated with NADPH and Mammalian Thioredoxin Reductase Yields Selenide, Which Inhibits Lipoxygenase and Changes the Electron Spin Resonance Spectrum of the Active Site Iron

Björnstedt, M., Odlander, B., Kuprin, S., Claesson, H., & Holmgren, A. (1996) · Biochemistry · doi:10.1021/bi9528762 · Cited by 54

Treatment of lung cancer cells with cytotoxic levels of sodium selenite: Effects on the thioredoxin system

Selenius, M., Fernandes, A. P., Brodin, O., Björnstedt, M., & Rundlöf, A.-K. (2008) · Biochemical Pharmacology · doi:10.1016/j.bcp.2008.02.028 · Cited by 53

Selenite is a potent cytotoxic agent for human primary AML cells

Olm, E., Jönsson‐Videsäter, K., Ribera‐Cortada, I., Fernandes, A. P., Eriksson, L. C., Lehmann, S., Rundlöf, A.-K., Paul, C., & Björnstedt, M. (2009) · Cancer Letters · doi:10.1016/j.canlet.2009.03.010 · Cited by 49

Inhibitory effects of thioredoxin reductase antisense RNA on the growth of human hepatocellular carcinoma cells

Gan, L., Yang, X., Liu, Q., & Xu, H. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20585 · Cited by 49

The role of thioredoxin reductase activity in selenium-induced cytotoxicity

Madeja, Z., Sroka, J., Nyström, C., Björkhem‐Bergman, L., Nordman, T., Damdimopoulos, A. E., Nalvarte, I., Eriksson, L. C., Spyrou, G., Olsson, J. M., et al. (2005) · Biochemical Pharmacology · doi:10.1016/j.bcp.2005.02.023 · Cited by 49

Inhibition of androgen receptor signaling by selenite and methylseleninic acid in prostate cancer cells: two distinct mechanisms of action

Husbeck, B., Bhattacharyya, R. S., Feldman, D., & Knox, S. J. (2006) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0056 · Cited by 49

Effect of long-term selenium yeast intervention on activity and gene expression of antioxidant and xenobiotic metabolising enzymes in healthy elderly volunteers from the Danish Prevention of Cancer by Intervention by Selenium (PRECISE) Pilot Study

Ravn‐Haren, G., Krath, B. N., Overvad, K., Cold, S., Moesgaard, S., Larsen, E. H., & Dragsted, L. O. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507882948 · Cited by 49

Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes

Osborne, S. A., & Tonissen, K. F. (2001) · BMC Genomics · doi:10.1186/1471-2164-2-10 · Cited by 46

Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density

Wang, Z., Hu, H., Li, G., Lee, H., Jiang, C., Kim, S., & Lü, J. (2007) · International Journal of Cancer · doi:10.1002/ijc.23077 · Cited by 45

Subchronic oral toxicity studies of Se-methylselenocysteine, an organoselenium compound for breast cancer prevention

Johnson, W. D., Morrissey, R. L., Kapetanović, I. M., Crowell, J. A., & McCormick, D. L. (2007) · Food and Chemical Toxicology · doi:10.1016/j.fct.2007.11.001 · Cited by 43

Effect of selenium on the immunocompetence of patients with head and neck cancer and on adoptive immunotherapy of early and established lesions

Kiremidjian‐Schumacher, L., & Roy, M.-C. (2001) · BioFactors · doi:10.1002/biof.5520140121 · Cited by 42

Human Thioredoxin Reductase Gene Localization to Chromosomal Position 12q23–q24.1 and mRNA Distribution in Human Tissue

Gasdaska, J. R., Gasdaska, P. Y., Gallegos, A. C., & Powis, G. (1996) · Genomics · doi:10.1006/geno.1996.0554 · Cited by 42

Quantification of alternative mRNA species and identification of thioredoxin reductase 1 isoforms in human tumor cells

Rundlöf, A.-K., Fernandes, A. P., Selenius, M., Babic, M., Shariatgorji, M., Nilsonne, G., Ilag, L. L., Dobra, K., & Björnstedt, M. (2006) · Differentiation · doi:10.1111/j.1432-0436.2006.00121.x · Cited by 41

Upregulation of 9 genes, including that for thioredoxin, during epithelial differentiation of mesothelioma cells

Sun, X., Dobra, K., Björnstedt, M., & Hjerpe, A. (2000) · Differentiation · doi:10.1046/j.1432-0436.2000.660404.x · Cited by 41

Sodium selenite as prophylaxis against erysipelas in secondary lymphedema.

Kasseroller, R. G. (1998) · PubMed · Cited by 35

Mechanisms of selenium chemoprevention and therapy in prostate cancer

Nadiminty, N., & Gao, A. C. (2008) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200700369 · Cited by 35

Selenite Activates Caspase-Independent Necrotic Cell Death in Jurkat T Cells and J774.2 Macrophages by Affecting Mitochondrial Oxidant Generation

Shilo, S., & Tirosh, O. (2003) · Antioxidants and Redox Signaling · doi:10.1089/152308603322110850 · Cited by 33

Antioxidant enzymes in oligodendroglial brain tumors: association with proliferation, apoptotic activity and survival

Järvelä, S., Bragge, H., Paunu, N., Timo, J., Paljärvi, L., Hannu, K., Pauli, H., Vuokko, K., Ylermi, S., & Hannu, H. (2005) · Journal of Neuro-Oncology · doi:10.1007/s11060-005-9030-z · Cited by 30

Increased levels of cytosolic thioredoxin reductase activity and mRNA in rat liver nodules

Björkhem, L., Teclebrhan, H., Kesen, E., Olsson, J. M., Eriksson, L. C., & Björnstedt, M. (2001) · Journal of Hepatology · doi:10.1016/s0168-8278(01)00113-1 · Cited by 30

Upregulation of 9 genes, including that for thioredoxin, during epithelial differentiation of mesothelioma cells

Sun, X., Dobra, K., Björnstedt, M., et al. (2000) · Differentiation · doi:10.1111/j.1432-0436.2000.660404.x · Cited by 25

Increased Expression of Specific Thioredoxin Family Proteins; A Pilot Immunohistochemical Study on Human Hepatocellular Carcinoma

Cunnea, P., Fernandes, A. P., Capitanio, A., Eken, S., Spyrou, G. P., & Björnstedt, M. (2007) · International Journal of Immunopathology and Pharmacology · doi:10.1177/039463200702000103 · Cited by 23

Selenium metabolism in rats with long-term ingestion of Se-methylselenocysteine using enriched stable isotopes

Tsuji, Y., Suzuki, N., Suzuki, K. T., & Ogra, Y. (2009) · The Journal of Toxicological Sciences · doi:10.2131/jts.34.191 · Cited by 23

Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure

Nilsonne, G., Olm, E., Szulkin, A., Mundt, F., Stein, A., Kocic, B., Rundlöf, A.-K., Fernandes, A. P., Björnstedt, M., & Dobra, K. (2009) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/1756-9966-28-92 · Cited by 23

Effects of the antioxidant Pycnogenol® on cellular redox systems in U1285 human lung carcinoma cells

Gandin, V., Nyström, C., Rundlöf, A.-K., Jönsson‐Videsäter, K., Schönlau, F., Hörkkö, J., Björnstedt, M., & Fernandes, A. P. (2008) · FEBS Journal · doi:10.1111/j.1742-4658.2008.06800.x · Cited by 22

Symptomatic treatment of brain tumor patients with sodium selenite, oxygen, and other supportive measures

Pakdaman, A. (1998) · Biological Trace Element Research · doi:10.1007/bf02820015 · Cited by 22

Phytochemicals in Broccoli Transcriptionally Induce Thioredoxin Reductase

Hintze, K. J., Wald, K., & Finley, J. W. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0580059 · Cited by 21

Effect of auranofin, an antirheumatic drug, on neutrophil apoptosis

Liu, J., Akahoshi, T., Namai, R., Matsui, T., & Kondo, H. (2000) · Inflammation Research · doi:10.1007/s000110050615 · Cited by 20

Inhibition Of Thioredoxin Reductase (E.C. 1.6.4.5.) By Antitumor Quinones

Bey-Liing, M., & Powis, G. (1990) · Free Radical Research Communications · doi:10.3109/10715769009053370 · Cited by 19

Detection of Thioredoxin in Gastric Cancer: Association with Histological Type

Noda, N., Ochiai, A., Miyazaki, K., Sügimura, T., Terada, M., & Wakasugi, H. (2000) · Antioxidants and Redox Signaling · doi:10.1089/15230860050192297 · Cited by 12

Se-methylselenocysteine sensitized TRAIL-mediated apoptosis via down-regulation of Bcl-2 expression

Kwon, H. N. (2009) · International Journal of Oncology · doi:10.3892/ijo_00000274 · Cited by 12

Bioactivation of Selenocysteine Derivatiives by β-Lyases Present in Common Gastrointestinal Bacterial Species

Schwiertz, A., Deubel, S., & Birringer, M. (2008) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831.78.45.169 · Cited by 10

Prevention of the development of melphalan resistance in vitro by selenite

Caffrey, P. B., Zhu, M. J., & Frenkel, G. D. (1998) · Biological Trace Element Research · doi:10.1007/bf02789095 · Cited by 8

Selenoproteins: Molecular Pathways and Physiological Roles

Labunskyy, V. M., Hatfield, D. L., & Gladyshev, V. N. (2014) · Physiological Reviews · doi:10.1152/physrev.00039.2013 · Cited by 1,452

Selenium in human health and disease

Fairweather-Tait, S. J., Bao, Y., Broadley, M. R., Collings, R., Ford, D., Hesketh, J. E., & Hurst, R. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2010.3275 · Cited by 1,330

Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

Tebay, L. E., Robertson, H., Durant, S. T., Vitale, S. R., Penning, T. M., Dinkova-Kostova, A. T., & Hayes, J. D. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.06.021 · Cited by 837

Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

Hanschmann, E.-M., Godoy, J. R., Berndt, C., Hudemann, C., & Lillig, C. H. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4599 · Cited by 696

Selenium and Selenoproteins: It’s Role in Regulation of Inflammation

Hariharan, S., & Dharmaraj, S. (2020) · Inflammopharmacology · doi:10.1007/s10787-020-00690-x · Cited by 659

Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium.

Gallegos, A. C., Berggren, M. I., Gasdaska, J. R., & Powis, G. (1997) · PubMed · Cited by 123

Selenium and the thioredoxin redox system: effects on cell growth and death.

Powis, G., Gasdaska, J. R., Gasdaska, P. Y., Berggren, M. I., Kirkpatrick, D. L., Engman, L., Cotgreave, I. A., Angulo, M., & Baker, A. F. (1997) · PubMed · Cited by 70

Thioredoxin reductase and selenium in carcinogenesis and multidrug resistance

Björkhem‐Bergman, L. (2004) · Open Archive (Karolinska Institutet)

Selenium as a cancer-protective agent

Nedvědová, M. (2012) · Digital Repository (National Repository of Grey Literature)

Thioredoxin Reductase 1 as an Anticancer Drug Target

Schmidt, E. E., & Arnér, E. S. J. (2016) · Springer eBooks · doi:10.1007/978-3-319-41283-2_16 · Cited by 9