Meta-analysis of the benefits of self-monitoring of blood glucose on glycemic control in type 2 diabetes patients: an update
Abstract
Background: Our systematic review and meta-analysis of the benefit of self-monitoring of blood glucose (SMBG) in improving glycemic control in type 2 diabetes was published in 2008. With the few studies that have emerged afterward, we undertook subsequent meta-analysis of the available evidence to update the results. Methods: Clinical trials of SMBG were identified through electronic searches (MEDLINE, EMBASE, and The Cochrane Library) up to and including June 2009. Studies were included if they met the following inclusion criteria: (1) randomized controlled trial comparing SMBG versus non-SMBG in type 2 diabetes patients not using insulin and (2) hemoglobin A1c (HbA 1c ) reported as an outcome measure. The efficacy was estimated with the mean difference in the changes of HbA 1c from baseline to final assessment between the SMBG and the non-SMBG groups. Results: SMBG was effective in reducing HbA 1c in non–insulin-treated type 2 diabetes (pooled mean difference, −0.24%; 95% confidence interval, −0.34% to −0.14%; P < 0.00001). Glycemic control significantly improved among the subgroup of patients whose baseline HbA 1c was ≥8%. In contrast, no significant effect of SMBG was detected in patients who had HbA 1c <8%. Conclusions: The available evidence suggests the usefulness of SMBG in improving glycemic control in non–insulin-treated type 2 diabetes as demonstrated by the reduction of HbA 1c levels. In particular, SMBG proved to be useful in the subgroup of patients whose baseline HbA 1c was ≥8%.
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The effect of SMBG on HbA1c was limited to patients with HbA1c values ≥8% (64 mmol/mol).
“The effect of SMBG was limited to patients with HbA 1c values $8% (64 mmol/mol).”
From Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus (2011) · cites this paper as [111]
Two recent systematic reviews reported small but significantly greater decreases in HbA1c with SMBG than controls in type 2 diabetes not treated with insulin.
“Two recent systematic reviews of randomized controlled studies of SMBG in people with type 2 diabetes not treated with insulin reported small but significantly greater decreases in HbA 1c among patients using SMBG than in controls (110,111).”
From Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus (2011) · cites this paper as [111]
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- Authors
- Poolsup, N., Suksomboon, N., & Rattanasookchit, S.
- Affiliations
- Silpakorn University (TH)
- Mahidol University (TH)
- Corresponding author
- Suksomboon, Naeti
- Venue
- Diabetes Technology & Therapeutics
- Publisher
- SAGE Publications
- Published
- 2009-12
- Volume
- 11
- Issue
- 12
- Pages
- 775-784
- ISSN
- 1520-9156 (ISSN-L)
- 1557-8593
- OpenAlex
- W2078427448
- Cited by
- 127
- References
- 35
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 2 · 2023: 1 · 2022: 5 · 2021: 3 · 2020: 10 · 2019: 11 · 2018: 9 · 2017: 7 · 2016: 3 · 2015: 3 · 2014: 7 · 2013: 17 · 2012: 16
- FWCI
- 1.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetes Technology & Therapeutics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- self-monitoring of blood glucose, type 2 diabetes, glycemic control, HbA1c, non-insulin-treated diabetes, baseline HbA1c, diabetes self-management
- MeSH terms
- Blood Glucose, Clinical Trials as Topic, Diabetes Mellitus, Type 2, Glycated Hemoglobin, Humans, Blood Glucose Self-Monitoring, Randomized Controlled Trials as Topic
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