The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Endothelialized Microvasculature Based on a Biodegradable Elastomer
Abstract
Vital organs maintain dense microvasculature to sustain the proper function of their cells. For tissue- engineered organs to function properly, artificial capillary networks must be developed. We have microfabricated capillary networks with a biodegradable and biocompatible elastomer, poly(glycerol sebacate) (PGS). We etched capillary patterns onto silicon wafers by standard micro-electromechanical systems (MEMS) techniques. The resultant silicon wafers served as micromolds for the devices. We bond the patterned PGS film with a flat film to create capillary networks that were perfused with a syringe pump at a physiological flow rate. The devices were endothelialized under flow conditions, and part of the lumens reached confluence within 14 days of culture. This approach may lead to tissue-engineered microvasculature that is critical in vital organs engineering.
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Cites
A tough biodegradable elastomer
Wang, Y., Ameer, G. A., Sheppard, B. J., & Langer, R. (2002) · Nature Biotechnology · doi:10.1038/nbt0602-602 · Cited by 1,314
Self-citationSELF-REGULATION OF GROWTH IN THREE DIMENSIONS
Folkman, J., & Hochberg, M. (1973) · The Journal of Experimental Medicine · doi:10.1084/jem.138.4.745 · Cited by 829
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Elastomeric biomaterials for tissue engineering
Chen, Q., Liang, S., & Thouas, G. A. (2013) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.05.003 · Cited by 564
Stimuli-responsive hydrogels in drug delivery and tissue engineering
Sood, N., Bhardwaj, A., Mehta, S., & Mehta, A. (2016) · Drug Delivery · doi:10.3109/10717544.2014.940091 · Cited by 426
Cell and protein compatibility of parylene-C surfaces
Chang, T. Y., Yadav, V. G., De Leo, S., Mohedas, A., Rajalingam, B., Chen, C.-L., Selvarasah, S., Dokmeci, M. R., & Khademhosseini, A. (2007) · Langmuir · doi:10.1021/la7017049 · Cited by 320
Vascularization—The Conduit to Viable Engineered Tissues
Kaully, T., Kaufman-Francis, K., Lesman, A., & Levenberg, S. (2009) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2008.0193 · Cited by 317
Vascularized Bone Tissue Engineering: Approaches for Potential Improvement
Nguyen, L. H., Annabi, N., Nikkhah, M., Bae, H., Binan, L., Park, S., Kang, Y., Yang, Y., & Khademhosseini, A. (2012) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2012.0012 · Cited by 313
Metadata
- Authors
- Fidkowski, C., Kaazempur-Mofrad, M. R., Borenstein, J., Vacanti, J. P., Langer, R., & Wang, Y.
- Venue
- Tissue Engineering
- Publisher
- SAGE Publications
- Published
- 2005-01
- Volume
- 11
- Issue
- 1-2
- Pages
- 302-309
- ISSN
- 1076-3279 (ISSN-L)
- 1557-8690
- OpenAlex
- W2017482231
- Cited by
- 343
- References
- 2
- FWCI
- 16.62
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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