The DOI matches its Crossref record; 121 of the 121 references it cites were found in a registry or an index.
Challenges in Cardiac Tissue Engineering
Open accessAbstract
Cardiac tissue engineering aims to create functional tissue constructs that can reestablish the structure and function of injured myocardium. Engineered constructs can also serve as high-fidelity models for studies of cardiac development and disease. In a general case, the biological potential of the cell-the actual "tissue engineer"-is mobilized by providing highly controllable three-dimensional environments that can mediate cell differentiation and functional assembly. For cardiac regeneration, some of the key requirements that need to be met are the selection of a human cell source, establishment of cardiac tissue matrix, electromechanical cell coupling, robust and stable contractile function, and functional vascularization. We review here the potential and challenges of cardiac tissue engineering for developing therapies that could prevent or reverse heart failure.
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Cites
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Cited by
3D Printing of Personalized Thick and Perfusable Cardiac Patches and Hearts
Noor, N., Shapira, A., Edri, R., Gal, I., Wertheim, L., & Dvir, T. (2019) · Advanced Science · doi:10.1002/advs.201900344 · Cited by 1,042
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Self-citationEngineered Microenvironments for Controlled Stem Cell Differentiation
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Self-citationSynthesis, properties and biomedical applications of poly(glycerol sebacate) (PGS): A review
Rai, R., Tallawi, M., Grigore, A., & Boccaccini, A. R. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.02.001 · Cited by 477
Metadata
- Authors
- Vunjak-Novakovic, G., Tandon, N., Godier, A., Maidhof, R., Marsano, A., Martens, T. P., & Radisic, M.
- Venue
- Tissue Engineering Part B: Reviews
- Publisher
- SAGE Publications
- Published
- 2010-04
- Volume
- 16
- Issue
- 2
- Pages
- 169-187
- ISSN
- 1937-3368 (ISSN-L)
- 1937-3376
- OpenAlex
- W1974388426
- Cited by
- 511
- References
- 121
- FWCI
- 24.30
- Type
- journal article
- Language
- en
- Open access
- green
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