Whole-Organ Tissue Engineering: Decellularization and Recellularization of Three-Dimensional Matrix Scaffolds

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

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Heart Disease and Stroke Statistics—2010 Update: A Report From the American Heart Association

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Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

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Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

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Bone Marrow as a Potential Source of Hepatic Oval Cells

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Tissue-engineered autologous bladders for patients needing cystoplasty

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Functional Arteries Grown in Vitro

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

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Immunosuppressive Drugs for Kidney Transplantation

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Endothelial Cells Stimulate Self-Renewal and Expand Neurogenesis of Neural Stem Cells

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Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix

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The role of bioreactors in tissue engineering

Martín, I., Wendt, D. J., & Heberer, M. (2003) · Trends in biotechnology · doi:10.1016/j.tibtech.2003.12.001 · Cited by 1,217 · see citing works

Tissue-Engineered Lungs for in Vivo Implantation

Petersen, T. H., Calle, E. A., Zhao, L., Lee, E. J., Gui, L., Raredon, M. S. B., Gavrilov, K., Yi, T., Zhuang, Z. W., Breuer, C. K., et al. (2010) · Science · doi:10.1126/science.1189345 · Cited by 1,177 · see citing works

Regeneration and orthotopic transplantation of a bioartificial lung

Ott, H. C., Clippinger, B., Conrad, C., Schuetz, C., Pomerantseva, I., Ikonomou, L., Kotton, D., & Vacanti, J. P. (2010) · Nature Medicine · doi:10.1038/nm.2193 · Cited by 1,090 · see citing works

Human tissue-engineered blood vessels for adult arterial revascularization

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Synthetic nano-scale fibrous extracellular matrix

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Vascularization Strategies for Tissue Engineering

Lovett, M. L., Lee, K., Edwards, A., & Kaplan, D. L. (2009) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2009.0085 · Cited by 923 · see citing works

Deaths: final data for 2006.

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The extracellular matrix as a scaffold for tissue reconstruction

Badylak, S. F. (2002) · Seminars in Cell and Developmental Biology · doi:10.1016/s1084952102000940 · Cited by 819 · see citing works

Acellular vascular tissues: natural biomaterials for tissue repair and tissue engineering

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Xenogeneic extracellular matrix as a scaffold for tissue reconstruction

Badylak, S. F. (2004) · Transplant Immunology · doi:10.1016/j.trim.2003.12.016 · Cited by 747 · see citing works

Macrophage Phenotype as a Determinant of Biologic Scaffold Remodeling

Badylak, S. F., Valentin, J. E., Ravindra, A. K., McCabe, G. P., & Stewart-Akers, A. M. (2008) · Tissue Engineering Part A · doi:10.1089/ten.tea.2007.0264 · Cited by 729 · see citing works

Cardiac Endothelial-Myocardial Signaling: Its Role in Cardiac Growth, Contractile Performance, and Rhythmicity

Brutsaert, D. L. (2003) · Physiological Reviews · doi:10.1152/physrev.00017.2002 · Cited by 697 · see citing works

Transplantation of undifferentiated murine embryonic stem cells in the heart: teratoma formation and immune response

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Transplantation of a Tissue-Engineered Pulmonary Artery

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Small intestinal submucosa as a large diameter vascular graft in the dog

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Identification of extractable growth factors from small intestinal submucosa

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Technique for Prolonged Normothermic Ex Vivo Lung Perfusion

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Challenges in Cardiac Tissue Engineering

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HEPATOCYTE TRANSPLANTATION AS A BRIDGE TO ORTHOTOPIC LIVER TRANSPLANTATION IN TERMINAL LIVER FAILURE

Strom, S. C., Fisher, R. A., Thompson, M. T., Sanyal, A. J., Cole, P. E., Ham, J. M., & Posner, M. P. (1997) · Transplantation · doi:10.1097/00007890-199702270-00014 · Cited by 516 · see citing works

The use of xenogeneic small intestinal submucosa as a biomaterial for Achille's tendon repair in a dog model

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United States Renal Data System (USRDS).

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Quantification of DNA in Biologic Scaffold Materials

Gilbert, T. W., Freund, J. M., & Badylak, S. F. (2008) · Journal of Surgical Research · doi:10.1016/j.jss.2008.02.013 · Cited by 482 · see citing works

The Basement Membrane Component of Biologic Scaffolds Derived from Extracellular Matrix

Brown, B. N., Lindberg, K., Reing, J. E., Stolz, D. B., & Badylak, S. F. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.519 · Cited by 436 · see citing works

Decellularization protocols of porcine heart valves differ importantly in efficiency of cell removal and susceptibility of the matrix to recellularization with human vascular cells

Rieder, E., Kasimir, M.-T., Silberhumer, G., Seebacher, G., Wolner, E., Simon, P., & Weigel, G. (2004) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2003.06.017 · Cited by 430 · see citing works

Decellularized Native and Engineered Arterial Scaffolds for Transplantation

Dahl, S. L. M., Koh, J., Prabhakar, V., & Niklason, L. E. (2003) · Cell Transplantation · doi:10.3727/000000003108747136 · Cited by 406 · see citing works

Influence of Acellular Natural Lung Matrix on Murine Embryonic Stem Cell Differentiation and Tissue Formation

Cortiella, J., Niles, J. A., Cantu, A., Brettler, A. C., Pham, A. N., Vargas, G., Winston, S., Wang, J. P., Walls, S., & Nichols, J. E. (2010) · Tissue Engineering Part A · doi:10.1089/ten.tea.2009.0730 · Cited by 381 · see citing works

Acellular collagen matrix as a possible “off the shelf” biomaterial for urethral repair

Chen, F. J., Yoo, J., & Atala, A. (1999) · Urology · doi:10.1016/s0090-4295(99)00179-x · Cited by 379 · see citing works

Tissue engineering of skin

Sophie Böttcher-haberzeth, A., Biedermann, T., & Ernst Reichmann, A. (2009) · Burns · doi:10.1016/j.burns.2009.08.016 · Cited by 358 · see citing works

Hepatocyte transplantation in acute liver failure

Bilir, B. M., GUINETTE, D., Karrer, F. M., Kumpe, D. A., Krysl, J., Stephens, J. K., McGavran, L., Ostrowska, A., & Durham, J. D. (2000) · Liver Transplantation · doi:10.1002/lt.500060113 · Cited by 358 · see citing works

Tissue-Engineered Blood Vessel for Adult Arterial Revascularization

L’Heureux, N., McAllister, T. N., & de la Fuente, L. M. (2007) · New England Journal of Medicine · doi:10.1056/nejmc071536 · Cited by 358 · see citing works

Vascular Endothelial Growth Factor in Porcine-Derived Extracellular Matrix

Hodde, J. P., Record, R. D., Liang, H.-L., & Badylak, S. F. (2001) · Endothelium · doi:10.3109/10623320109063154 · Cited by 348 · see citing works

Commercial Extracellular Matrix Scaffolds for Rotator Cuff Tendon Repair

Derwin, K. A., Baker, A. R., Spragg, R. K., et al. (2006) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.e.01307 · Cited by 347 · see citing works

Survival Following Liver Transplantation From Non-Heart-Beating Donors

Abt, P. L., Desai, N. M., Crawford, M. D., et al. (2003) · Annals of Surgery · doi:10.1097/01.sla.0000103063.82181.2c · Cited by 346 · see citing works

Development of a Decellularized Lung Bioreactor System for Bioengineering the Lung: The Matrix Reloaded

Price, A., England, K. A., Matson, A. M., Blazar, B. R., & Panoskaltsis‐Mortari, A. (2010) · Tissue Engineering Part A · doi:10.1089/ten.tea.2009.0659 · Cited by 344 · see citing works

Tissue engineering of heart valves – human endothelial cell seeding of detergent acellularized porcine valves1

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Preparation of Cardiac Extracellular Matrix from an Intact Porcine Heart

Wainwright, J. M., Czajka, C. A., Patel, U. B., Freytes, D. O., Tobita, K., Gilbert, T. W., & Badylak, S. F. (2009) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2009.0392 · Cited by 327 · see citing works

Experimental assessment of small intestinal submucosa as a bladder wall substitute

Kropp, B. P., Eppley, B. L., Prevel, C. D., Rippy, M. K., Harruff, R. C., Badylak, S. F., Adams, M. C., Rink, R. C., & Keating, M. A. (1995) · Urology · doi:10.1016/s0090-4295(99)80227-1 · Cited by 320 · see citing works

Microfabrication of Hepatocyte/Fibroblast Co-cultures: Role of Homotypic Cell Interactions

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Nucleotide sequences of complementary deoxyribonucleic acids for the pro.alpha.1 chain of human type I procollagen. Statistical evaluation of structures that are conserved during evolution

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Impact of decellularization of xenogeneic tissue on extracellular matrix integrity for tissue engineering of heart valves

Schenke-Layland, K., Vasilevski, O., Opitz, F., König, K., Riemann, I., Halbhuber, K. J., Wahlers, T., & Stock, U. A. (2003) · Journal of Structural Biology · doi:10.1016/j.jsb.2003.08.002 · Cited by 302 · see citing works

Normothermic Perfusion

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Process development of an acellular dermal matrix (ADM) for biomedical applications

Chen, R.-N., Ho, H., Tsai, Y.-T., & Sheu, M. (2003) · Biomaterials · doi:10.1016/j.biomaterials.2003.09.070 · Cited by 298 · see citing works

Lung epithelial cell lines in coculture with human pulmonary microvascular endothelial cells: development of an alveolo-capillary barrier in vitro

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Molecular Mechanisms Underlying the Dedifferentiation Process of Isolated Hepatocytes and Their Cultures

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Pancreatic stem cells

Bonner‐Weir, S., & Sharma, A. (2002) · The Journal of Pathology · doi:10.1002/path.1158 · Cited by 283 · see citing works

Maintenance of Human Hepatocyte Function In Vitro by Liver-Derived Extracellular Matrix Gels

Sellaro, T. L., Ranade, A. R., Faulk, D. M., McCabe, G. P., Dorko, K., Badylak, S. F., & Strom, S. C. (2009) · Tissue Engineering Part A · doi:10.1089/ten.tea.2008.0587 · Cited by 276 · see citing works

The Culture of Whole Organs

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Histological evaluation of decellularised porcine aortic valves: matrix changes due to different decellularisation methods

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Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells

Evseenko, D. A., Zhu, Y., Schenke‐Layland, K., Kuo, J., Latour, B. L., Ge, S., Scholes, J., Dravid, G. G., Li, X., MacLellan, W. R., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002077107 · Cited by 258 · see citing works

Development and evaluation of a novel decellularized vascular xenograft

Conklin, B. S., Richter, E. R., Kreutziger, K. L., Zhong, D., & Chen, C. (2002) · Medical Engineering & Physics · doi:10.1016/s1350-4533(02)00010-3 · Cited by 254 · see citing works

Structure of a cDNA for the pro.alpha.2 chain of human type I procollagen. Comparison with chick cDNA for pro.alpha.2(I) identifies structurally conserved features of the protein and the gene

Bernard, M. P., Myers, J. C., Chu, M. L., Ramirez, F., Eikenberry, E. F., & Prockop, D. J. (1983) · Biochemistry · doi:10.1021/bi00274a023 · Cited by 251 · see citing works

Biological background of dermal substitutes

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Liver Stem Cells: Implications for Hepatocarcinogenesis

Alison, M. R. (2005) · Stem Cell Reviews and Reports · doi:10.1385/scr:1:3:253 · Cited by 246 · see citing works

Revascularization of Human Acellular Dermis in Full-Thickness Abdominal Wall Reconstruction in the Rabbit Model

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Antibacterial Activity within Degradation Products of Biological Scaffolds Composed of Extracellular Matrix

Brennan-Pierce, E. P., Reing, J. E., Chew, D. W., Myers-Irvin, J. M., Young, E., & Badylak, S. F. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.2949 · Cited by 239 · see citing works

Tissue Engineering: The End of the Beginning

Lysaght, M. J., & Hazlehurst, A. L. (2004) · Tissue Engineering · doi:10.1089/107632704322791943 · Cited by 239 · see citing works

Assessing Porcine Liver-Derived Biomatrix for Hepatic Tissue Engineering

Lin, P., Chan, W. C. W., Badylak, S. F., & Bhatia, S. N. (2004) · Tissue Engineering · doi:10.1089/ten.2004.10.1046 · Cited by 236 · see citing works

Biaxial strength of multilaminated extracellular matrix scaffolds

Freytes, D. O., Badylak, S. F., Webster, T. J., Geddes, L. A., & Rundell, A. E. (2003) · Biomaterials · doi:10.1016/j.biomaterials.2003.09.015 · Cited by 235 · see citing works

Tissue engineering of cardiac valve prostheses I: development and histological characterization of an acellular porcine scaffold.

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Maintenance of Hepatic Sinusoidal Endothelial Cell Phenotype In Vitro Using Organ-Specific Extracellular Matrix Scaffolds

Sellaro, T. L., Ravindra, A. K., Stolz, D. B., & Badylak, S. F. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0437 · Cited by 214 · see citing works

Comparison of Different Decellularization Procedures of Porcine Heart Valves

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Allogeneic hematopoietic cell transplantation: the state of the art

Gyurkocza, B., Rezvani, A. R., & Storb, R. F. (2010) · Expert Review of Hematology · doi:10.1586/ehm.10.21 · Cited by 207 · see citing works

Bone tissue engineering with human stem cells

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Dynamic reciprocity: how do extracellular matrix and hormones direct gene expression?

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Hepatic tissue engineering

Kulig, K. M., & Vacanti, J. P. (2004) · Transplant Immunology · doi:10.1016/j.trim.2003.12.005 · Cited by 187 · see citing works

Antimicrobial Activity Associated with Extracellular Matrices

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First human transplantation of a bioengineered airway tissue

Macchiarini, P., Walles, T., Biancosino, C., & Mertsching, H. (2004) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2004.02.042 · Cited by 176 · see citing works

Stem cells, cell transplantation and liver repopulation

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Effect of the αGal Epitope on the Response to Small Intestinal Submucosa Extracellular Matrix in a Nonhuman Primate Model

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Transplant Outcomes in Mucopolysaccharidoses

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Stem cells derived from amniotic fluid: new potentials in regenerative medicine

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Inosculation: Connecting the Life-Sustaining Pipelines

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Bioreactors and Bioprocessing for Tissue Engineering

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Production and characterization of ECM powder: implications for tissue engineering applications

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Tissue engineering of cardiac valve prostheses II: biomechanical characterization of decellularized porcine aortic heart valves.

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Integration of Technologies for Hepatic Tissue Engineering

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Galα(1,3)Gal Epitope in Porcine Small Intestinal Submucosa

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Long‐term maintenance of hepatocyte functional activity in co‐culture: Requirements for sinusoidal endothelial cells and dexamethasone

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Bioreactor-based roadmap for the translation of tissue engineering strategies into clinical products

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