The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
The Early Fracture Hematoma and Its Potential Role in Fracture Healing
Abstract
Research regarding the potency and potential of the fracture hematoma has begun to receive increasing attention. However, currently there is a paucity of relevant literature on the capability and composition of the fracture hematoma. This review briefly summarizes the regenerative fracture healing process and the close interplay between the skeletal and immune systems. The role of immune cells in wound healing is also discussed to clarify their involvement in immunological processes during regeneration. We attempt to describe the current state of knowledge regarding the fracture hematoma as the initial stage of the regenerative process of fracture healing. The review discusses how a better understanding of immune reactions in the hematoma may have implications for bone tissue engineering strategies. We conclude the review by emphasizing how additional investigations of the initial phase of healing will allow us to better differentiate between deleterious and beneficial aspects of inflammation, thereby facilitating improved fracture treatment strategies.
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Citations
Cites
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Cited by
Inflammation, fracture and bone repair
Loi, F., Córdova, L. A., Pajarinen, J., Lin, T.-H., Yao, Z., & Goodman, S. B. (2016) · Bone · doi:10.1016/j.bone.2016.02.020 · Cited by 1,293
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Cellular biology of fracture healing
Bahney, C. S., Zondervan, R. L., Allison, P., Theologis, A., Ashley, J. W., Ahn, J., Miclau, T., Marcucio, R. S., & Hankenson, K. D. (2019) · Journal of Orthopaedic Research · doi:10.1002/jor.24170 · Cited by 577
The multifaceted role of fibrinogen in tissue injury and inflammation
Luyendyk, J. P., Schoenecker, J. G., & Flick, M. J. (2019) · Blood · doi:10.1182/blood-2018-07-818211 · Cited by 555
Bone fracture healing in mechanobiological modeling: A review of principles and methods
Ghiasi, M. S., Chen, J., Vaziri, A., Rodriguez, E. K., & Nazarian, A. (2017) · Bone Reports · doi:10.1016/j.bonr.2017.03.002 · Cited by 485
Metadata
- Authors
- Kolar, P., Schmidt-Bleek, K., Schell, H., Gaber, T., Toben, D., Schmidmaier, G., Perka, C., Buttgereit, F., & Duda, G. N.
- Venue
- Tissue Engineering Part B: Reviews
- Publisher
- SAGE Publications
- Published
- 2010-08
- Volume
- 16
- Issue
- 4
- Pages
- 427-434
- ISSN
- 1937-3368 (ISSN-L)
- 1937-3376
- OpenAlex
- W2074226229
- Cited by
- 403
- References
- 56
- FWCI
- 10.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kolar, P., Schmidt-Bleek, K., Schell, H., Gaber, T., Toben, D., Schmidmaier, G., Perka, C., Buttgereit, F., & Duda, G. N. (2010). The Early Fracture Hematoma and Its Potential Role in Fracture Healing. Tissue Engineering Part B: Reviews. https://doi.org/10.1089/ten.teb.2009.0687
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
