OSTEOIMMUNOLOGY: Interplay Between the Immune System and Bone Metabolism

Osteoclast differentiation and activation

Boyle, W. J., Simonet, W. S., & Lacey, D. L. (2003) · Nature · doi:10.1038/nature01658 · Cited by 6,670 · cited 2× · see citing works

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.

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Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.

Simonet, W. S., Lacey, D. L., Dunstan, C. R., Kelley, M., Chang, M.-S., Lüthy, R., Nguyen, H. Q., Wooden, S., Bennett, L., Boone, T., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80209-3 · Cited by 5,130 · see citing works

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L., & Karsenty, G. (1997) · Cell · doi:10.1016/s0092-8674(00)80257-3 · Cited by 4,246 · see citing works

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

Yasuda, H., Shima, N., Nakagawa, N., Yamaguchi, K., Kinosaki, M., Mochizuki, S.-I., Tomoyasu, A., Yano, K., Goto, M., Murakami, A., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.7.3597 · Cited by 4,224 · see citing works

Bone Resorption by Osteoclasts

Teitelbaum, S. L. (2000) · Science · doi:10.1126/science.289.5484.1504 · Cited by 3,962 · see citing works

The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation

Nakashima, K., Zhou, X., Kunkel, G., Zhang, Z., Deng, J. M., Behringer, R. R., & de Crombrugghe, B. (2002) · Cell · doi:10.1016/s0092-8674(01)00622-5 · Cited by 3,608 · see citing works

Osteoblastic cells regulate the haematopoietic stem cell niche

Calvi, L. M., Adams, G. B., Weibrecht, K. W., Weber, J. M., Olson, D. P., Knight, M. C., Martin, R. P., Schipani, E., Pajevic, P. D., Bringhurst, F. R., et al. (2003) · Nature · doi:10.1038/nature02040 · Cited by 3,452 · see citing works

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis.

Kong, Y.-Y., Yoshida, H., Sarosi, I., Tan, H.-L., Timms, E., Capparelli, C., Morony, S., Oliveira-dos-Santos, A. J., Van, G., Itie, A., et al. (1999) · Nature · doi:10.1038/16852 · Cited by 3,351 · see citing works

STATs: transcriptional control and biological impact

Levy, D. E., & Darnell, J. E. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm909 · Cited by 3,201 · see citing works

Identification of the haematopoietic stem cell niche and control of the niche size

Zhang, J., Niu, C. S., Ye, L., Huang, H., He, X. C., Tong, W.-G., Ross, J., Haug, J., Johnson, T. J., Feng, J. Q., et al. (2003) · Nature · doi:10.1038/nature02041 · Cited by 2,948 · see citing works

Metastasis to bone: causes, consequences and therapeutic opportunities

Mundy, G. R. (2002) · Nature reviews. Cancer · doi:10.1038/nrc867 · Cited by 2,787 · see citing works

Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

Takayanagi, H., Kim, S., Koga, T., Nishina, H., Isshiki, M., Yoshida, H., Saiura, A., Isobe, M., Yokochi, T., Inoue, J.-I., et al. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00369-6 · Cited by 2,701 · see citing works

Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.

Bucay, N., Sarosi, I., Dunstan, C. R., Morony, S., Tarpley, J., Capparelli, C., Scully, S., Tan, H. L., Xu, W., Lacey, D. L., et al. (1998) · Genes & Development · doi:10.1101/gad.12.9.1260 · Cited by 2,483 · see citing works

TLR signaling pathways

Takeda, K., & Akira, S. (2004) · Seminars in Immunology · doi:10.1016/j.smim.2003.10.003 · Cited by 2,461 · see citing works

Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

Suda, T., Takahashi, N., Udagawa, N., Jimi, E., Gillespie, M. T., & Martin, T. J. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0367 · Cited by 2,317 · see citing works

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.

Anderson, D. M., Maraskovsky, E., Billingsley, W. L., Dougall, W. C., Tometsko, M. E., Roux, E. R., Teepe, M. C., DuBose, R. F., Cosman, D., & Galibert, L. (1997) · Nature · doi:10.1038/36593 · Cited by 2,290 · see citing works

LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development

Gong, Y., Slee, R. B., Fukai, N., Rawadi, G., Roman-Roman, S., Reginato, A. M., Wang, H., Cundy, T., Glorieux, F. H., Lev, D., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00571-2 · Cited by 2,235 · see citing works

Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche

Arai, F., Hirao, A., Ohmura, M., Sato, H., Matsuoka, S., Takubo, K., Ito, K., Koh, G. Y., & Suda, T. (2004) · Cell · doi:10.1016/j.cell.2004.07.004 · Cited by 1,958 · see citing works

Involutional Osteoporosis

Riggs, B. L., & Melton, L. J. (1986) · New England Journal of Medicine · doi:10.1056/nejm198606263142605 · Cited by 1,919 · see citing works

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand.

Kong, Y.-Y., Feige, U., Sarosi, I., Bolon, B., Tafuri, A., Morony, S., Capparelli, C., Li, J., Elliott, R., McCabe, S., et al. (1999) · Nature · doi:10.1038/46303 · Cited by 1,856 · see citing works

High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5

Boyden, L. M., Mao, J., Belsky, J., Mitzner, L., Farhi, A., Mitnick, M. A., Wu, D., Insogna, K., & Lifton, R. P. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013444 · Cited by 1,591 · see citing works

RANK is essential for osteoclast and lymph node development.

Dougall, W. C., Glaccum, M., Charrier, K., Rohrbach, K., Brasel, K., De Smedt, T., Daro, E., Smith, J., Tometsko, M. E., Maliszewski, C. R., et al. (1999) · Genes & Development · doi:10.1101/gad.13.18.2412 · Cited by 1,478 · see citing works

T-Cell mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ.

Takayanagi, H., Ogasawara, K., Hida, S., Chiba, T., Murata, S., Sato, K., Takaoka, A., Yokochi, T., Oda, H., Tanaka, K., et al. (2000) · Nature · doi:10.1038/35046102 · Cited by 1,358 · see citing works

A Mutation in the LDL Receptor–Related Protein 5 Gene Results in the Autosomal Dominant High–Bone-Mass Trait

Little, R. D., Folz, C., Manning, S. P., Swain, P. M., Zhao, S.-C., Eustace, B., Lappe, M. M., Spitzer, L., Zweier, S., Braunschweiger, K., et al. (2002) · The American Journal of Human Genetics · doi:10.1086/338450 · Cited by 1,282 · see citing works

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingPreprint

Lomaga, M. A., Yeh, W., Sarosi, I., Duncan, G. S., Furlonger, C. L., Ho, A. P., Morony, S., Capparelli, C., Van, G. Y., Kaufman, S., et al. (1999) · Genes & Development · doi:10.1101/gad.13.8.1015 · Cited by 1,253 · see citing works

Humoral Immunity Due to Long-Lived Plasma Cells

Slifka, M. K., Antia, R., Whitmire, J. K., & Ahmed, R. (1998) · Immunity · doi:10.1016/s1074-7613(00)80541-5 · Cited by 1,249 · see citing works

BCMA Is Essential for the Survival of Long-lived Bone Marrow Plasma Cells

O’Connor, B. P., Raman, V. S., Erickson, L. D., Cook, W. J., Weaver, L. K., Ahonen, C. L., Lin, L.-L., Mantchev, G. T., Bram, R. J., & Noelle, R. J. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031330 · Cited by 1,130 · see citing works

<i>Cbfa1</i>-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

Kato, M., Patel, M. S., Levasseur, R., Lobov, I., Chang, B. H.-J., Glass, D. A., Hartmann, C., Li, L., Hwang, T.-H., Brayton, C. F., et al. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200201089 · Cited by 1,086 · see citing works

TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells

Wong, B. R., Rho, J., Arron, J. R., Robinson, E. A., Orlinick, J. R., Chao, M. V., Kalachikov, S. M., Cayani, E., Bartlett, F. S., Frankel, W. N., et al. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.40.25190 · Cited by 1,042 · see citing works

A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation

Lee, N. K., Choi, Y. G., Baik, J. Y., Han, S.-Y., Jeong, D.-W., Bae, Y. S., Kim, N., & Lee, S. Y. (2005) · Blood · doi:10.1182/blood-2004-09-3662 · Cited by 961 · see citing works

Regulation of osteoblastogenesis and bone mass by Wnt10b

Bennett, C. N., Longo, K. A., Hahn, W. S., Suva, L. J., Lane, T. F., Hankenson, K. D., & MacDougald, O. A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408742102 · Cited by 882 · see citing works

Regulation of plasma-cell development

Shelef, M. A., & Calame, K. L. (2005) · Nature reviews. Immunology · doi:10.1038/nri1572 · Cited by 881 · see citing works

TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor.

Wong, B. R., Josien, R., Lee, S. Y., Sauter, B., Li, H.-L., Steinman, R. M., & Choi, Y. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.12.2075 · Cited by 853 · see citing works

Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

Celeste, A. J., Iannazzi, J. A., Taylor, R. C., et al. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.24.9843 · Cited by 831 · see citing works

Bone versus immune system

Arron, J. R., & Choi, Y. (2000) · Nature · doi:10.1038/35046196 · Cited by 828 · see citing works

Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis

Koga, T., Inui, M., Inoue, K., Kim, S., Suematsu, A., Kobayashi, E., Iwata, T., Ohnishi, H., Matozaki, T., Kodama, T., et al. (2004) · Nature · doi:10.1038/nature02444 · Cited by 828 · see citing works

RANK-L and RANK: T Cells, Bone Loss, and Mammalian Evolution

Theill, L. E., Boyle, W. J., & Penninger, J. M. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.100301.064753 · Cited by 817 · see citing works

TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis.

Pettit, A. R., Ji, H., von Stechow, D., Müller, R., Goldring, S. R., Choi, Y., Benoist, C., & Gravallese, E. M. (2001) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63016-7 · Cited by 807 · see citing works

Visualizing dendritic cell networks in vivo

Lindquist, R. L., Shakhar, G., Dudziak, D., Wardemann, H., Eisenreich, T., Dustin, M. L., & Nussenzweig, M. C. (2004) · Nature Immunology · doi:10.1038/ni1139 · Cited by 806 · see citing works

Hematopoiesis is severely altered in mice with an induced osteoblast deficiency

Višnjić, D., Kalajzić, Ž., Rowe, D. W., Katavić, V., Lorenzo, J., & Aguila, H. L. (2004) · Blood · doi:10.1182/blood-2003-11-4011 · Cited by 804 · see citing works

Cellular Niches Controlling B Lymphocyte Behavior within Bone Marrow during Development

Tokoyoda, K., Egawa, T., Sugiyama, T., Choi, B.-I., & Nagasawa, T. (2004) · Immunity · doi:10.1016/j.immuni.2004.05.001 · Cited by 796 · see citing works

Signaling Pathways for PC12 Cell Differentiation: Making the Right Connections

Vaudry, D., Stork, P. A., Lazarovici, P., & Eiden, L. E. (2002) · Science · doi:10.1126/science.1071552 · Cited by 795 · see citing works

Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis.

Tsuda, E., Goto, M., Mochizuki, S.-I., Yano, K., Kobayashi, F., Morinaga, T., & Higashio, K. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6603 · Cited by 787 · see citing works

Generic Signals and Specific Outcomes

Crabtree, G. R. (1999) · Cell · doi:10.1016/s0092-8674(00)80571-1 · Cited by 730 · see citing works

RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β

Takayanagi, H., Kim, S., Matsuo, K., Suzuki, H. I., Suzuki, T., Sato, K., Yokochi, T., Oda, H., Nakamura, K., Ida, N., et al. (2002) · Nature · doi:10.1038/416744a · Cited by 719 · see citing works

Dynamic Imaging of T Cell-Dendritic Cell Interactions in Lymph Nodes

Stoll, S., Delon, J., Brotz, T. M., & Germain, R. N. (2002) · Science · doi:10.1126/science.1071065 · Cited by 718 · see citing works

Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-α

Cenci, S., Weitzmann, M. N., Roggia, C., Namba, N., Novack, D., Woodring, J., & Pacifici, R. (2000) · Journal of Clinical Investigation · doi:10.1172/jci11066 · Cited by 705 · see citing works

Distinct molecular mechanism for initiating TRAF6 signalling

Ye, H., Arron, J. R., Lamothe, B., Cirilli, M., Kobayashi, T., Shevde, N. K., Segal, D., Dzivenu, O. K., Vologodskaia, M., Yim, M., et al. (2002) · Nature · doi:10.1038/nature00888 · Cited by 665 · see citing works

Severe osteopetrosis, defective interleukin‐1 signalling and lymph node organogenesis in TRAF6‐deficient mice

Naito, A., Azuma, S., Tanaka, S., Miyazaki, T., Takaki, S., Takatsu, K., Nakao, K., Nakamura, K., Katsuki, M., Yamamoto, T. S., et al. (1999) · Genes to Cells · doi:10.1046/j.1365-2443.1999.00265.x · Cited by 626 · see citing works

Metabolic bone disease

Avioli, L. V., & Krane, S. M. (1977) · Cited by 624 · see citing works

TRANCE, a TNF Family Member, Activates Akt/PKB through a Signaling Complex Involving TRAF6 and c-Src

Wong, B. R., Besser, D., Kim, N., Arron, J. R., Vologodskaia, M., Hanafusa, H., & Choi, Y. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80232-4 · Cited by 593 · see citing works

Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines

Jilka, R. L., Weinstein, R. S., Bellido, T., Parfitt, A. M., & Manolagas, S. C. (1998) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1998.13.5.793 · Cited by 578 · see citing works

Signal Transduction Mediated by the T Cell Antigen Receptor: The Role of Adapter Proteins

Samelson, L. E. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.092601.111357 · Cited by 572 · see citing works

Bone resorbing activity in supernatant fluid from cultured human peripheral blood leukocytes

Horton, J. E., Raisz, L. G., Simmons, H. A., Oppenheim, J. J., & Mergenhagen, S. E. (1972) · Science · doi:10.1126/science.177.4051.793 · Cited by 565 · see citing works

TRANCE Is Necessary and Sufficient for Osteoblast-mediated Activation of Bone Resorption in Osteoclasts

Fuller, K., Wong, B., Fox, S. W., Choi, Y., & Chambers, T. J. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.5.997 · Cited by 562 · see citing works

Inhibition of Osteoblast Differentiation by Tumor Necrosis Factor-α*

Gilbert, L., He, X., Farmer, P., Boden, S., Kozlowski, M., Rubin, J., & Nanes, M. S. (2000) · Endocrinology · doi:10.1210/endo.141.11.7739 · Cited by 555 · see citing works

Stat1-dependent and -independent pathways in IFN-γ-dependent signaling

Ramana, C. V., Gil, M. P., Schreiber, R. D., & Stark, G. R. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(01)02118-4 · Cited by 555 · see citing works

Marked Decrease in Plasma Antioxidants in Aged Osteoporotic Women: Results of a Cross-Sectional Study

Maggio, D., Barabani, M., Pierandrei, M., Polidori, M. C., Catani, M., Mecocci, P., Senin, U., Pacifici, R., & Cherubini, A. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021496 · Cited by 531 · see citing works

Purification and partial sequence of human osteoclast-activating factor: identity with interleukin 1 beta.

Dewhirst, F. E., Stashenko, P., Mole, J. E., & Tsurumachi, T. (1985) · The Journal of Immunology · doi:10.4049/jimmunol.135.4.2562 · Cited by 507 · see citing works

Bacterially induced bone destruction: mechanisms and misconceptions

Nair, S. P., Meghji, S., Wilson, M., Reddi, K., White, P. A., & Henderson, B. E. (1996) · Infection and Immunity · doi:10.1128/iai.64.7.2371-2380.1996 · Cited by 505 · see citing works

Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection

Teng, Y.-T. A., Nguyen, H. P., Gao, X., Kong, Y., Gorczynski, R. M., Singh, B., Ellen, R. P., & Penninger, J. M. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10763 · Cited by 494 · see citing works

Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals

Cassese, G., Arce, S., Hauser, A. E., Lehnert, K., Moewes, B., Mostarac, M., Muehlinghaus, G., Szyska, M., Radbruch, A., & Manz, R. A. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.4.1684 · Cited by 487 · see citing works

Cancer and Bone

Guise, T. A., & Mundy, G. R. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.1.0323 · Cited by 487 · see citing works

The interferon-α/β system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors

Taniguchi, T., & Takaoka, A. (2002) · Current Opinion in Immunology · doi:10.1016/s0952-7915(01)00305-3 · Cited by 482 · see citing works

Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis

Hughes, A. E., Ralston, S. H., Marken, J., Bell, C., Macpherson, H. K., Wallace, R. G. H., Hul, W. V., Whyte, M. P., Nakatsuka, K., Hovy, L., et al. (2000) · Nature Genetics · doi:10.1038/71667 · Cited by 481 · see citing works

Regulation of Osteoblast Formation and Function

Aubin, J. E. (2001) · Reviews in Endocrine and Metabolic Disorders · doi:10.1023/a:1010011209064 · Cited by 468 · see citing works

The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor

Wong, B. R., Josien, R., Lee, S. Y., Vologodskaia, M., Steinman, R. M., & Choi, Y. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.43.28355 · Cited by 458 · see citing works

Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs

Kamath, A. T., Henri, S., Battye, F. L., Tough, D. F., & Shortman, K. (2002) · Blood · doi:10.1182/blood.v100.5.1734.h81702001734_1734_1741 · Cited by 454 · see citing works

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

Traverse, S., Seedorf, K., Paterson, H., Marshall, C., Cohen, P., & Ullrich, A. (1994) · Current Biology · doi:10.1016/s0960-9822(00)00154-8 · Cited by 454 · see citing works

Osteoprotegerin Deficiency and Juvenile Paget's Disease

Whyte, M. P., Obrecht, S. E., Finnegan, P. M., Jones, J. L., Podgornik, M. N., McAlister, W. H., & Mumm, S. R. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013096 · Cited by 446 · see citing works

The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase

Mócsai, A., Humphrey, M., Ziffle, J. V. V., Hu, Y., Burghardt, A., Spusta, S. C., Majumdar, S., Lanier, L., Lowell, C., & Nakamura, M. C. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401602101 · Cited by 436 · see citing works

Characterization of the Intracellular Domain of Receptor Activator of NF-κB (RANK)

Darnay, B. G., Haridas, V., Ni, J., Moore, P. A., & Aggarwal, B. B. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.32.20551 · Cited by 414 · see citing works

Mechanistic insight into osteoclast differentiation in osteoimmunology

Takayanagi, H. (2005) · Journal of Molecular Medicine · doi:10.1007/s00109-004-0612-6 · Cited by 413 · see citing works

Dendritic Cell Development and Survival Require Distinct NF-κB Subunits

Ouaaz, F., Arron, J. R., Zheng, Y., Choi, Y., & Beg, A. A. (2002) · Immunity · doi:10.1016/s1074-7613(02)00272-8 · Cited by 389 · see citing works

Bone Marrow Is a Major Reservoir and Site of Recruitment for Central Memory CD8+ T Cells

Mazo, I. B., Honczarenko, M., Leung, H. C. H., Cavanagh, L. L., Bonasio, R., Weninger, W., Engelke, K., Xia, L., McEver, R. P., Koni, P. A., et al. (2005) · Immunity · doi:10.1016/j.immuni.2005.01.008 · Cited by 381 · see citing works

The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

Roy, M., Waldschmidt, T. J., Aruffo, A. A., et al. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.151.5.2497 · Cited by 371 · see citing works

Bone marrow as a priming site for T-cell responses to blood-borne antigen

Feuerer, M., Beckhove, P., Garbi, N., Mahnke, Y. D., Limmer, A., Hommel, M., Hämmerling, G., Kyewski, B., Hamann, A., Umansky, V., et al. (2003) · Nature Medicine · doi:10.1038/nm914 · Cited by 369 · see citing works

Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation

Matsuo, K., Owens, J., Tonko, M., Elliott, C., Chambers, T. J., & Wagner, E. F. (2000) · Nature Genetics · doi:10.1038/72855 · Cited by 341 · see citing works

TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo

Josien, R., Li, H.-L., Ingulli, E., Sarma, S., R.Wong, B., Vologodskaia, M., Steinman, R. M., & Choi, Y. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.191.3.495 · Cited by 334 · see citing works

Stable T cell–dendritic cell interactions precede the development of both tolerance and immunity in vivo

Shakhar, G., Lindquist, R. L., Skokos, D., Dudziak, D., Huang, J. H. Y., Nussenzweig, M. C., & Dustin, M. L. (2005) · Nature Immunology · doi:10.1038/ni1210 · Cited by 333 · see citing works

Immature dendritic cell transdifferentiation into osteoclasts: a novel pathway sustained by the rheumatoid arthritis microenvironment

Rivollier, A., Mazzorana, M., Tebib, J. G., Piperno, M., Aitsiselmi, T., Rabourdin‐Combe, C., Jurdic, P., & Delprat, C. (2004) · Blood · doi:10.1182/blood-2004-01-0041 · Cited by 323 · see citing works

TRANCE, a TNF Family Member, Is Differentially Expressed on T Cell Subsets and Induces Cytokine Production in Dendritic Cells

Josien, R., Wong, B. R., Li, H., Steinman, R. M., & Choi, Y. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.5.2562 · Cited by 317 · see citing works

Intrinsic Constraint on Plasmablast Growth and Extrinsic Limits of Plasma Cell Survival

Sze, D., Toellner, K., Vinuesa, C. G., et al. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.6.813 · Cited by 317 · see citing works

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