The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Diagnostic Accuracy of Conventional Versus Sonography-Guided Fine-Needle Aspiration Biopsy of Thyroid Nodules
Abstract
Fine-needle aspiration biopsy (FNAB) is an accurate, slightly invasive, and safe method for the preoperative diagnosis of thyroid nodules. Recently, ultrasound guidance has been suggested as a valuable aid to enhance FNAB diagnostic performance. In this study, we have compared diagnostic accuracy of conventional FNAB (C-FNAB) versus sonography-guided FNAB (SG-FNAB) on a large sample population of 9683 patients with thyroid nodules. Over a 15-year period, 4986 patients were investigated by C-FNAB and 4697 underwent SG-FNAB. A valid cytological diagnosis was obtained in 85.9% of C-FNAB and in 91.5% of SG-FNAB cases, allowing detection of thyroid cancer in 1.6% and 2.1% of patients, respectively. The indeterminate pattern of follicular neoplasia was observed in 238 C-FNAB (5%) and in 272 (5.4%) SG-FNAB nodules. Specimens were cytologically inadequate in 433 C-FNAB (8.7%), but only in 167 SG-FNAB cases (3.5%). A total of 535 C-FNAB and 540 SG-FNAB nodules underwent surgery. False-negative results occurred in 7 C-FNAB nodules (2.3%), but only in 3 SG-FNAB cases (1%). Sensitivity, specificity, and global diagnostic accuracy of C-FNAB compared with SG-FNAB were 91.8% versus 97.1%, 68.8% versus 70.9%, and 72.6% versus 75.9%, respectively. Our results, based on a large population of thyroid nodules, demonstrate that SG-FNAB allows a more precise and adequate sampling of thyroid nodular lesions and is associated with a lower rate of false-negatives, thus improving global diagnostic accuracy in the preoperative selection of thyroid cancer.
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Citations
Cites
Management of a Solitary Thyroid Nodule
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Fine-Needle Aspiration Biopsy of the Thyroid: An Appraisal
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Fine-Needle Aspiration Cytology of the Thyroid: A 12-Year Experience With 11,000 Biopsies
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Sources of diagnostic error in fine needle aspiration of the thyroid
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Fine-Needle Aspiration Biopsy of the Thyroid: The Problem of Suspicious Cytologic Findings
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Cystic thyroid nodules. The dilemma of malignant lesions
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Impact on Thyroid Practice and Cost of Care
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Diagnosis of thyroid nodules by fine-needle aspiration biopsy
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Cited by
Haugen, B. R., Alexander, E. K., Bible, K. C., Doherty, G. M., Mandel, S. J., Nikiforov, Y. E., Pacini, F., Randolph, G. W., Sawka, A. M., Schlumberger, M., et al. (2016) · Thyroid® · doi:10.1089/thy.2015.0020 · Cited by 16,535
Cooper, D. S., Doherty, G. M., Haugen, B. R., Kloos, R. T., Lee, S. L., Mandel, S. J., Mazzaferri, E. L., McIver, B., Pacini, F., Schlumberger, M., et al. (2009) · Thyroid · doi:10.1089/thy.2009.0110 · Cited by 6,707
Long-term assessment of a multidisciplinary approach to thyroid nodule diagnostic evaluation
Yassa, L., Cibas, E. S., Benson, C. B., Frates, M. C., Doubilet, P. M., Gawande, A. A., Moore, F. D., Kim, B. W., Nosé, V., Marqusee, E., et al. (2007) · Cancer · doi:10.1002/cncr.23116 · Cited by 718
Management of Simple Nodular Goiter: Current Status and Future Perspectives
Hegedüs, L., Bonnema, S. J., & Bennedbæk, F. N. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0016 · Cited by 710
Continuing Controversies in the Management of Thyroid Nodules
Castro, M. R., & Gharib, H. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-11-200506070-00011 · Cited by 256
Metadata
- Authors
- DANESE, D., SCIACCHITANO, S., FARSETTI, A., ANDREOLI, M., & PONTECORVI, A.
- Venue
- Thyroid
- Publisher
- SAGE Publications
- Published
- 1998-01
- Volume
- 8
- Issue
- 1
- Pages
- 15-21
- ISSN
- 1050-7256 (ISSN-L)
- 1557-9077
- OpenAlex
- W2131301146
- Cited by
- 522
- References
- 14
- FWCI
- 8.84
- Type
- journal article
- Language
- en
- Open access
- closed
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