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Cited by 133Nutrition and Health in AgingClinical Nutrition and GastroenterologyDysphagia Assessment and Management

Prevention of malnutrition in older people during and after hospitalisation: results from a randomised controlled clinical trial

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Gazzotti, C.·2003·Age and Ageing
DOI 10.1093/ageing/32.3.321
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Abstract

OBJECTIVE: to prevent the occurrence of weight loss during hospitalisation and following discharge by daily oral supplementation. DESIGN: in a prospective, randomised, controlled study of 80 patients aged 75 or more, and at risk of undernutrition based on their initial Mini Nutritional Assessment score, patients were randomised into a control group or one receiving oral supplementation. The intervention was a prescription of 200 ml sweet or salty sip feed twice daily (500 kcal, 21 g protein per day) throughout hospitalisation and convalescence. Nutritional status was assessed at baseline and after 2 months using Mini Nutritional Assessment and body weight record. RESULTS: compliance with oral supplementation was good and daily extra energy intake was 407+/-184 kcal. On day 60, significant weight loss from upon admission was observed in the control group (-1.23+/-2.5 kg; P=0.01), but not in the supplemented group (0.28+/-3.8 kg; NS). At the end of the study, Mini Nutritional Assessment scores were higher in the supplemented group than in the control group (23.5+/-3.9 versus 20.8+/-3.6; P<0.01). CONCLUSION: use of daily oral supplementation during and after hospitalisation maintains body weight and increases Mini Nutritional Assessment score in patients at risk of undernutrition.

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  • In a prospective RCT of 80 patients aged 75 years or more admitted for acute disease and at risk for malnutrition, a 60-day intervention with ONS started in hospital and continued at home or in the nursing home resulted in maintained body weight and improved MNA scores (3.01±2.65 vs 1.81±2.97, p=0.004), whereas control patients continued to lose weight.

    “Similarly, in a prospective RCT of 80 patients aged 75 years or more admitted for acute disease and at risk for malnutrition, a 60-day intervention with ONS which started in hospital and was continued at home or in the nursing home resulted in maintained body weight and improved MNA scores (3.01 ± 2.65 vs. 1.81 ± 2.97), p ¼ 0.004), whereas CG patients continued to lose weight”

    From ESPEN guideline on nutritional support for polymorbid medical inpatients (2023) · cites this paper as [117]

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Authors
Gazzotti, C.
Affiliations
Centre hospitalier régional de la Citadelle (BE)
Corresponding author
Gazzotti, C.
Venue
Age and Ageing
Publisher
Oxford University Press (OUP)
Published
2003-05-01
Volume
32
Issue
3
Pages
321-325
ISSN
  • 0002-0729 (ISSN-L)
  • 1468-2834
DOI
10.1093/ageing/32.3.321
OpenAlex
W2161346944
Cited by
133
References
3
Citations by year
2026: 2 · 2025: 4 · 2024: 4 · 2023: 1 · 2022: 6 · 2021: 7 · 2020: 2 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 6 · 2015: 12 · 2014: 4 · 2013: 11 · 2012: 9
FWCI
3.98
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Age and Ageing (publishedVersion)
  • PubMed (publishedVersion)
  • Open Repository and Bibliography (University of Liège) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Health Professions › Speech and Hearing › Dysphagia Assessment and Management
Keywords
malnutrition prevention, older adults, hospitalization, weight loss, oral nutritional supplementation, malnutrition, Mini Nutritional Assessment, nutritional status, post-discharge recovery, protein intake
MeSH terms
Aged, Aged, 80 and over, Female, Hospitalization, Humans, Male, Protein-Energy Malnutrition, Weight Loss, Nutrition Assessment, Dietary Supplements

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