Estimation of extracellular and total body water by multiple-frequency bioelectrical-impedance measurement
Abstract
This study evaluated a new technology of bioelectrical-impedance (BI) measurement that makes use of multiple frequencies (5, 50, and 100 kHz) for estimation of extracellular and total body water. In 36 healthy males, resistance and reactance at three frequencies were compared with extra-cellular water (ECW) and total body water (TBW) determined by isotope dilution. ECW was best predicted by resistance measured at 5 kHz, corrected for height and weight (R = 0.930, SEE = 1.94 L) whereas TBW was best predicted by resistance at 100 kHZ and weight (R = 0.947, SEE = 2.64 L). Cross-validation analysis on two randomly selected subsets (n = 18 each) indicated that the prediction equations were reproducible and valid. Thus, BI at dual frequencies is valid for determination of body-water compartments and may be useful in the nutritional assessment of patients in whom body water and hydration is of clinical concern.
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The study tested its equations against earlier published BIA equations whose development samples Dioum et al. assumed included at least some black participants.
“Performance of developed equations for the prediction of FFM was also tested using all available data (n=362) against previously published equations derived using participant samples which were assumed by Dioum et al. to consist of at least some ethnically black participants (5, 24–32).”
From Prediction of fat-free mass using bioelectrical impedance analysis in young adults from five populations of African origin (2013) · cites this paper as [30]
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- Authors
- Segal, K., Burastero, S., Chun, A., Coronel, P., Pierson, R., & Wang, J.
- Affiliations
- Mount Sinai Health System (US)
- Corresponding author
- Segal, KR
- ORCID
- Wang, J
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1991-07
- Volume
- 54
- Issue
- 1
- Pages
- 26-29
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2153250908
- Cited by
- 311
- References
- 15
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 6 · 2023: 6 · 2022: 4 · 2021: 6 · 2020: 5 · 2019: 9 · 2018: 8 · 2017: 12 · 2016: 5 · 2015: 11 · 2014: 10 · 2013: 8 · 2012: 5
- FWCI
- 7.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (DK-37352, DK37948, R01DK037352, R01DK037948)
- Topics
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrical and Bioimpedance Tomography
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Keywords
- bioimpedance, extracellular water, total body water, body water compartments, hydration assessment, nutritional assessment
- MeSH terms
- Adult, Body Water, Electric Conductivity, Extracellular Space, Humans, Male, Middle Aged, Radioisotope Dilution Technique, Regression Analysis, Reproducibility of Results, Nutrition Assessment
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