Body composition in growth hormone deficient adults

Binnerts, A; Deurenberg, P; Swart, GR; Wilson, JH; Lamberts, S W J

doi:10.1093/ajcn/55.5.918

Cited by 159Body Composition Measurement TechniquesGrowth Hormone and Insulin-like Growth FactorsHormonal and reproductive studies

Body composition in growth hormone deficient adults

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Binnerts, A, Deurenberg, P, Swart, GR, Wilson, JH, Lamberts, S W J·1992·The American Journal of Clinical Nutrition

DOI 10.1093/ajcn/55.5.918

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Abstract

Body composition in a group of growth hormone (GH)-deficient adults was compared with a control group matched for age, sex, body height, body weight, and body mass index by using bioelectrical impedance and deuterium oxide-dilution methods and hydrodensitometry. The body-fat percentages of GH-deficient adults were higher despite comparable weight, height, age, and body mass index. Body impedance was higher in the GH-deficient adults after correction for differences in height and fat-free mass. As a consequence, prediction formulas for body composition from body impedance developed in normal subjects cannot be applied to GH-deficient subjects. The higher body impedance in the GH-deficient subjects can be ascribed to a smaller amount of extracellular water in these subjects than in control subjects.

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The frequency of TSH deficiency relative to other anterior pituitary hormone abnormalities in pituitary disorders is variable.
“The frequency of TSH deficiency with relation to other anterior pituitary hormone abnormalities, in pituitary disorders, is variable (50,51).”
From Anterior Pituitary Dysfunction in Survivors of Traumatic Brain Injury (2004) · cites this paper as [51]
Long-term adult GH deficiency is associated with reduced lean body mass.
“reduced lean body mass (25)”
From Post-Traumatic Hypopituitarism—Who Should Be Screened, When, and How? (2018) · cites this paper as [25]

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Authors: Binnerts, A., Deurenberg, P., Swart, G., Wilson, J., & Lamberts, S. W. J.
Affiliations: Academisch Ziekenhuis Rotterdam (NL)
Corresponding author: Lamberts, S W J
ORCID: Wilson, JH
Venue: The American Journal of Clinical Nutrition
Publisher: Elsevier BV
Published: 1992-05
Volume: 55
Issue: 5
Pages: 918-923
ISSN: 0002-9165 (ISSN-L)
DOI: 10.1093/ajcn/55.5.918
OpenAlex: W2098999072
Cited by: 159
References: 46
Citations by year: 2024: 1 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 5 · 2018: 5 · 2017: 2 · 2016: 1 · 2015: 4 · 2013: 4 · 2012: 3
FWCI: 4.67
Type: journal article
Language: en
Open access: green
research.wur.nl
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: American Journal of Clinical Nutrition (publishedVersion)
PubMed (publishedVersion)
Socio-Environmental Systems Modeling (acceptedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Topics: Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
Keywords: growth hormone deficiency, body composition, body fat percentage, bioimpedance, deuterium dilution, hydrodensitometry, extracellular water, fat-free mass, prediction formula, adults
MeSH terms: Adipose Tissue, Adult, Body Composition, Body Height, Body Water, Body Weight, Craniopharyngioma, Densitometry, Female, Humans, Hypopituitarism, Male, Middle Aged, Regression Analysis, Growth Hormone, Body Mass Index

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Body composition in growth hormone deficient adults

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