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Cited by 98Muscle metabolism and nutritionSports Performance and TrainingCardiovascular and exercise physiology

Muscle glycogen storage after prolonged exercise: effect of the frequency of carbohydrate feedings

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Burke, LM, Collier, GR, Davis, PG, Fricker, PA, Sanigorski, AJ, Hargreaves, M·1996·The American Journal of Clinical Nutrition
DOI 10.1093/ajcn/64.1.115
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Abstract

We reported previously that intake of carbohydrate foods with a high glycemic index (GI) produced greater glycogen storage and greater postprandial glucose and insulin responses during 24 h of postexercise recovery than did intake of low-GI carbohydrate foods. In the present study we examined the importance of the greater incremental glucose and insulin concentrations on glycogen repletion by comparing intake of large carbohydrate meals ("gorging") with a pattern of frequent, small, carbohydrate snacks ("nibbling"), which simulates the flattened glucose and insulin responses after low-GI carbohydrate meals. Eight well-trained triathletes [x +/- SEM: 25.6 +/- 1.5 y of age, weighing 70.2 +/- 1.9 kg, and with a maximal oxygen uptake (VO2max) of 4.2 +/- 0.2 L/min] undertook an exercise trial (2 h at 75% VO2max followed by four 30-s sprints) to deplete muscle glycogen on two occasions, 1 wk apart For 24 h after each trial, subjects rested and consumed the same diet composed exclusively of high-GI carbohydrate foods, providing 10 g carbohydrate/kg body mass. The "gorging" trial provided the food as four large meals of equal carbohydrate content eaten at 0, 4, 8, and 20 h of recovery, whereas in the "nibbling" trial each of the meals was divided into four snacks and fed at hourly intervals (0-11, 20-23 h). However, there was no significant difference in muscle glycogen storage between the two groups over the 24 h (gorging: 74.1 +/- 8.0 mmol/kg wet wt; nibbling: 94.5 +/- 14.6 mmol/kg wet wt). The results of this study suggest that there is no difference in postexercise glycogen storage over 24 h when a high-carbohydrate diet is fed as small frequent snacks or as large meals, and that a mechanism other than lowered blood glucose and insulin concentrations needs to be sought to explain the reduced rate of glycogen storage after consumption of low-GI carbohydrate foods.

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  • The frequency of intake of the recommended amounts of CHO (e.g. large meals versus a series of snacks) does not affect glycogen storage in longer-term recovery, despite marked differences in blood glucose and insulin responses.

    “The frequency of intake of the recommended amounts of CHO (e.g. large meals versus a series of snacks) does not affect glycogen storage in longer-term recovery, despite marked differences in blood glucose and insulin responses (21, 28).”

    From Postexercise muscle glycogen resynthesis in humans. (2017) · cites this paper as [21]

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1 of the 27 references couldn’t be matched to a known paper.

Research works printed but not linked: 5

  1. [5]5. Ivy JL, Lee MC, Brozinick JT, Reed MJ. Muscle glycogen storage aisnt dn t diatn l t di dsil 1988;65:2018–23.
  2. [9]9. car on mrh mr r de sm rton runners. Eur J Appl Physiol 1988;57:70–4.
  3. [11]11. Wolever TMS. The glycemic index. In: Bourne GH, ed. Aspects of some vitamins, minerals and enzymes in health and disease. World Rev Nutr Diet 1990;62:120–85.
  4. [17]17. Jenkins DJA, Wolever TMS, Ocana AM, et al. Metabolic effects of reo su u us u o es uous sipping. Diabetes 1990;39:775–81.
  5. [23]23. Burke LM, Collier GR, Beasley SK, et al. Effect of coingestion of fat yrs n n s e ad e J Appl Physiol 1995;78:2187–92.

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Authors
Burke, L., Collier, G., Davis, P., Fricker, P., Sanigorski, A., & Hargreaves, M.
ORCID
Hargreaves, M
Venue
The American Journal of Clinical Nutrition
Publisher
Elsevier BV
Published
1996-07
Volume
64
Issue
1
Pages
115-119
ISSN
0002-9165 (ISSN-L)
DOI
10.1093/ajcn/64.1.115
OpenAlex
W2138088767
Cited by
98
References
27
Citations by year
2026: 2 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 4 · 2015: 6 · 2014: 4 · 2013: 7 · 2012: 3
FWCI
0.40
Type
journal article
Language
en
Open access
Licence
Locations
  • American Journal of Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • Own your potential (DEAKIN) (submittedVersion)
  • Figshare (submittedVersion, cc-by)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
muscle glycogen storage, glycogen repletion, post-exercise recovery, low glycemic index carbohydrates, nibbling, postprandial blood glucose, insulin response, triathletes, endurance exercise
MeSH terms
Adult, Blood Glucose, Dietary Carbohydrates, Glycogen, Humans, Insulin, Muscles, Oxygen Consumption, Sports, Time Factors, Exercise

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