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Cited by 227Muscle metabolism and nutritionSports Performance and TrainingMetabolism, Diabetes, and Cancer

Muscle glycogen storage after different amounts of carbohydrate ingestion

Ivy, J. L., Lee, M. C., Brozinick, J. T., Reed, M. J.·1988·Journal of Applied Physiology
DOI 10.1152/jappl.1988.65.5.2018
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Abstract

The purpose of this study was to determine whether the rate of muscle glycogen storage could be enhanced during the initial 4-h period postexercise by substantially increasing the amount of the carbohydrate consumed. Eight subjects cycled for 2 h on three separate occasions to deplete their muscle glycogen stores. Immediately and 2 h after exercise they consumed either 0 (P), 1.5 (L), or 3.0 g glucose/kg body wt (H) from a 50% glucose polymer solution. Blood samples were drawn from an antecubital vein before exercise, during exercise, and throughout recovery. Muscle biopsies were taken from the vastus lateralis immediately, 2 h, and 4 h after exercise. Blood glucose and insulin declined significantly during exercise in each of the three treatments. They remained below the preexercise concentrations during recovery in the P treatment but increased significantly above the preexercise concentrations during the L and H treatments. By the end of the 4 h-recovery period, blood glucose and insulin were still significantly above the preexercise concentrations in both treatments. Muscle glycogen storage was significantly increased above the basal rate (P, 0.5 mumol.g wet wt-1.h-1) after ingestion of either glucose polymer supplement. The rates of muscle glycogen storage, however, were not different between the L and H treatments during the first 2 h (L, 5.2 +/- 0.9 vs. H, 5.8 +/- 0.7 mumol.g wet wt-1.h-1) or the second 2 h of recovery (L, 4.0 +/- 0.9 vs. H, 4.5 +/- 0.6 mumol.g wet wt-…

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Crossref · 10.1152/jappl.1988.65.5.2018

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  • In the hours following exercise, carbohydrate ingestion is a requirement for substantial repletion of liver and skeletal muscle glycogen stores.

    “In the hours following exercise, carbohydrate ingestion is a requirement for substantial repletion of liver and skeletal muscle glycogen stores (Ivy et al. 1988; Casey et al. 2000; van Hall et al. 2000).”

    From Fructose co‐ingestion to increase carbohydrate availability in athletes (2019) · cites this paper as Ivy et al. 1988

  • Net muscle glycogen (re)synthesis rates during 4 h of post-exercise recovery in the fasted state are in the range of approximately 2-12 mmol/kg dw/h.

    “It has previously been demonstrated that net muscle glycogen (re)synthesis rates during 4 h of post‐exercise recovery in the fasted state are in the range of ∼2–12 mmol/kg dw/h (Maehlum & Hermansen, 1978; Ivy et al. 1988; van Hall et al. 2000), with no net muscle glycogen (re)synthesis observed beyond 4 h of recovery (Maehlum & Hermansen, 1978).”

    From Fructose co‐ingestion to increase carbohydrate availability in athletes (2019) · cites this paper as Ivy et al. 1988

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Authors
Ivy, J. L., Lee, M. C., Brozinick, J. T., & Reed, M. J.
Affiliations
The University of Texas at Austin (US)
ORCID
Brozinick, J. T.
Venue
Journal of Applied Physiology
Publisher
American Physiological Society
Published
1988-11-01
Volume
65
Issue
5
Pages
2018-2023
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
DOI
10.1152/jappl.1988.65.5.2018
OpenAlex
W2136060691
Cited by
227
References
0
Citations by year
2026: 1 · 2025: 1 · 2024: 3 · 2023: 8 · 2022: 3 · 2021: 8 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 8 · 2016: 5 · 2015: 8 · 2014: 6 · 2013: 13 · 2012: 11
FWCI
0.92
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Applied Physiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
Keywords
muscle glycogen storage, carbohydrate intake, glucose polymers, post-exercise recovery, glycogen resynthesis, insulin, blood glucose, cycling exercise, vastus lateralis
MeSH terms
Blood Glucose, Dietary Carbohydrates, Physical Exertion, Glycogen, Glycogen Synthase, Humans, Insulin, Lactates, Male, Muscles, Pulmonary Gas Exchange, Lactic Acid

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