l-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial

“Mini-mental state”

Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282

The Fatigue Severity Scale: Application to Patients With Multiple Sclerosis and Systemic Lupus Erythematosus

Krupp, L. B. (1989) · Archives of Neurology · doi:10.1001/archneur.1989.00520460115022 · Cited by 6,172

A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Wallace, D. C. (2005) · Annual Review of Genetics · doi:10.1146/annurev.genet.39.110304.095751 · Cited by 3,185

Studies of Illness in the Aged: The Index of ADL: A Standardized Measure of Biological and Psychosocial Function

Katz, S. (1963) · JAMA · doi:10.1001/jama.1963.03060120024016 · Cited by 2,421

World Medical Association Declaration of Helsinki: Recommendations Guiding Physicians in Biomedical Research Involving Human Subjects

(1997) · JAMA · doi:10.1001/jama.1997.03540350075038 · Cited by 1,023

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl- l -carnitine and/or R -α-lipoic acid

Liu, J., Head, E., Gharib, A., Yuan, W., Ingersoll, R. T., Hagen, T. M., Cotman, C. W., & Ames, B. N. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.261709299 · Cited by 504

Fatigue syndromes: a comparison of chronic "postviral" fatigue with neuromuscular and affective disorders.

Wessely, S. C., & Powell, R. (1989) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.52.8.940 · Cited by 478

A method for the determination of carnitine in the picomole range

Cederblad, G., & Lindstedt, S. (1972) · Clinica Chimica Acta · doi:10.1016/0009-8981(72)90438-x · Cited by 457

Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression

Pettegrew, J. W., Levine, J., & McClure, R. J. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000805 · Cited by 304

Carnitine metabolism in the fasting rat.

Brass, E. P., & Hoppel, C. L. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40875-1 · Cited by 302

Fatigue and Fatigability in Older Adults

Eldadah, B. A. (2010) · PM&R · doi:10.1016/j.pmrj.2010.03.022 · Cited by 262

Mitochondrial Dysfunction and Chronic Disease: Treatment With Natural Supplements.

Nicolson, G. L. (2014) · PubMed Central · Cited by 235

The mitochondrial free radical theory of ageing - Where do we stand?

Gruber, J. (2008) · Frontiers in bioscience · doi:10.2741/3174 · Cited by 171

Fatigue in multiple sclerosis – Insights into evaluation and management

Ayache, S. S., & Chalah, M. A. (2017) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2017.02.004 · Cited by 163

Enzymology of the carnitine biosynthesis pathway

Strijbis, K., Vaz, F. M., & Distel, B. (2010) · IUBMB Life · doi:10.1002/iub.323 · Cited by 155

L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and

Malaguarnera, M., Cammalleri, L., Gargante, M. P., Vacante, M., Colonna, V., & Motta, M. (2007) · Cited by 1

Levocarnitine Administration in Elderly Subjects with Rapid Muscle Fatigue

Pistone, G., Marino, A. D., Leotta, C., Dell'Arte, S., Finocchiaro, G., & Malaguarnera, M. (2003) · Drugs & Aging · doi:10.2165/00002512-200320100-00004 · Cited by 86

Efecto de la suplementación de L-Carnitina en la naturaleza y severidad de la fatiga y en las funciones cognitivas en una población de ancianos

González, C. A. (2015) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Acetyl l-carnitine (ALC) treatment in elderly patients with fatigue

Malaguarnera, M., Gargante, M. P., Cristaldi, E., Colonna, V., Messano, M., Koverech, A., Neri, S., Vacante, M., Cammalleri, L., & Motta, M. (2007) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2007.03.012 · Cited by 85

AGG-1728; No of Pages 10 Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue

Michele Malaguarnera, A., Gargante, M. P., Erika Cristaldi, A., Valentina Colonna, A., Messano, M., Aleardo Koverech, B., Sergio Neri, C., Vacante, M., Lisa Cammalleri, D., & Massimo Motta, D. (2015)

Effects of Citric Acid and L-Carnitine on Physical Fatigue

Sugino, T., Aoyagi, S., Shirai, T., Kajimoto, Y., & Kajimoto, O. (2007) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.2007032 · Cited by 39

L-carnitine supplementation improves fatigue, mood and sleep in cancer patients with fatigue and carnitine deficiency

Cruciani, R. A., Dvorkin, E., Homel, P., Culliney, B. E., Malamud, S. C., Shaiova, L., Lapin, J., Blum, R. H., Lesage, P., Portenoy, R. K., et al. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2006.24.18_suppl.8588 · Cited by 2

Levocarnitine helps improve symptoms of physical and mental fatigue in the elderly,

&NA; (2006) · Inpharma Weekly · doi:10.2165/00128413-200615370-00042

L-Carnitine Supplementation in Patients with Advanced Cancer and Carnitine Deficiency: A Double-Blind, Placebo-Controlled Study

Cruciani, R. A., Dvorkin, E., Homel, P., Culliney, B. E., Malamud, S. C., Lapin, J., Portenoy, R. K., & Esteban-Cruciani, N. (2008) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2008.03.021 · Cited by 66

Efficacy of L-carnitine supplementation on frailty status and its biomarkers, nutritional status, and physical and cognitive function among prefrail older adults: a double-blind, randomized, placebo-controlled clinical trial

Badrasawi, M., Shahar, S., Zahara, A. M., Rajab, N. F., & Singh, D. K. A. (2016) · DOAJ (DOAJ: Directory of Open Access Journals)