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Dietary leucine requirement of older men and women is higher than current recommendations
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“Thus, dietary protein recommendations for older adults should be increased (i.e., ≥30 g/meal or ≥1.2 g/kg body mass/day), which contain higher amounts of leucine (i.e., 78.5 mg/kg body mass/day) than current recommendations [198], and also considered on a meal-by-meal (every 3–4 h) basis [199,200].”
From Nutrition for Older Athletes: Focus on Sex-Differences (2021) · cites this paper as [198]
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Leucine co-ingestion improves post-prandial muscle protein accretion in elderly men
Wall, B. T., Hamer, H. M., de Lange, A., Kiskini, A., Groen, B. B. L., Senden, J. M. G., Gijsen, A. P., Verdijk, L. B., & van Loon, L. J. C. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2012.09.002 · Cited by 220
Bukhari, S. S. I., Phillips, B. E., Wilkinson, D. J., Limb, M. C., Rankin, D., Mitchell, W. K., Kobayashi, H., Greenhaff, P. L., Smith, K., & Atherton, P. J. (2015) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00481.2014 · Cited by 162
Devries, M. C., McGlory, C., Bolster, D. R., Kamil, A., Rahn, M., Harkness, L., Baker, S. K., & Phillips, S. M. (2018) · The Journal of Nutrition · doi:10.1093/jn/nxy091 · Cited by 141 · cited 5×
“Interestingly, when the MPS response to leucine intake is compared across studies of older males and females (15, 39, 40, 42, 43), females exhibit stimulation of MPS, albeit to a lesser extent than seen in males, suggestive of a reduced responsiveness of MPS to stimulation by leucine.”
BackgroundInfluentialMurphy, C. H., Saddler, N. I., Devries, M. C., McGlory, C., Baker, S. K., & Phillips, S. M. (2016) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.136424 · Cited by 133
Rafii, M., Chapman, K., Owens, J., Elango, R., Campbell, W. W., Ball, R. O., Pencharz, P. B., & Courtney-Martin, G. (2015) · The Journal of Nutrition · doi:10.3945/jn.114.197517 · Cited by 122
Self-citation
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Cited by
Strategies to Prevent Sarcopenia in the Aging Process: Role of Protein Intake and Exercise
Rogeri, P. S., Zanella, R., Martins, G. L., Garcia, M. D. A., Leite, G., Lugaresi, R., Gasparini, S. O., Sperandio, G. A., Ferreira, L. H. B., Souza-Junior, T. P., et al. (2021) · Nutrients · doi:10.3390/nu14010052 · Cited by 181
Cereda, E., Pisati, R., Rondanelli, M., & Caccialanza, R. (2022) · Nutrients · doi:10.3390/nu14071524 · Cited by 139
Chen, Y., Wang, H., Lu, W., Wu, T., Yuan, W., Zhu, J., Lee, Y. K., Zhao, J., Zhang, H., & Chen, W. (2022) · Gut Microbes · doi:10.1080/19490976.2021.2025016 · Cited by 94
Moura, M. A. F. E., Martins, B. D. A., Oliveira, G. P. D., & Takahashi, J. A. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2085657 · Cited by 78
Nichele, S., Phillips, S. M., & Boaventura, B. C. B. (2022) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2021-0806 · Cited by 61
Metadata
- Authors
- Szwiega, S., Pencharz, P. B., Rafii, M., Lebarron, M., Chang, J., Ball, R. O., Kong, D., Xu, L., Elango, R., & Courtney-Martin, G.
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2021-02
- Volume
- 113
- Issue
- 2
- Pages
- 410-419
- ISSN
- 0002-9165
- Cited by
- 77
- References
- 13
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 729 d)
- Funders
- Canadian Institutes of Health Research (MT 10321)
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- Szwiega, S., Pencharz, P. B., Rafii, M., Lebarron, M., Chang, J., Ball, R. O., Kong, D., Xu, L., Elango, R., & Courtney-Martin, G. (2021). Dietary leucine requirement of older men and women is higher than current recommendations. The American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn/nqaa323
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