Molecular signatures database (MSigDB) 3.0

Cited by (1,039)

Items 201–300 of 1,039

1. Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia
   Shih, Alan H., Jiang, Yanwen, Meydan, Cem, Shank, Kaitlyn, Pandey, Suveg, Barreyro, Laura, Antony-Debre, Ileana, Viale, Agnes, Socci, Nicholas, Sun, Yongming et al. · 2015 · Cancer Cell
2. A Description of the Molecular Signatures Database (MSigDB) Web Site
   Arthur Liberzon · 2014 · Methods in molecular biology
3. CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy
   Lauren Giuffrida, Kevin Sek, Melissa A. Henderson, Junyun Lai, Amanda X.Y. Chen, Déborah Meyran, Kirsten L. Todd, Emma V. Petley, Sherly Mardiana, Christina Mølck et al. · 2021 · Nature Communications
4. CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis
   Yifan Zhang, Guangjian Liu, Qianwen Zeng, Wenrui Wu, Kai Lei, Chuankai Zhang, Miaoling Tang, Yuting Zhang, Xiao Xiang, Li Tan et al. · 2024 · Cancer Cell
5. Pan-cancer proteomic map of 949 human cell lines
   Emanuel Gonçalves, Rebecca C. Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth Srinivas Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall et al. · 2022 · Cancer Cell
6. BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression
   David Barras, Edoardo Missiaglia, Pratyaksha Wirapati, Oliver M. Sieber, Robert N. Jorissen, Chris Love, Peter L. Molloy, Ian T. Jones, Stephen McLaughlin, Peter Gibbs et al. · 2016 · Clinical Cancer Research
7. Integrative pathway enrichment analysis of multivariate omics data
   Marta Paczkowska, Jonathan Barenboim, Nardnisa Sintupisut, Natalie S. Fox, Helen Zhu, Diala Abd-Rabbo, Miles W. Mee, Paul Christopher Boutros, PCAWG Drivers and Functional Interpretation Working Group, Federico Abascal et al. · 2020 · Nature Communications
8. Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway
   Tsing-Lee Tang-Huau, Paul Gueguen, Christel Goudot, Mélanie Durand, Mylène Bohec, Sylvain Baulande, Benoit Pasquier, Sebastián Amigorena, Élodie Segura · 2018 · Nature Communications
9. Systems biology primer: the basic methods and approaches
   Iman Tavassoly, Joseph Goldfarb, Ravi Iyengar · 2018 · Essays in Biochemistry
10. Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
    Elizabeth A. Bowling, Jarey H. Wang, Fade Gong, William Wu, Nicholas J. Neill, Ik Sun Kim, Siddhartha Tyagi, Mayra C. Orellana, Sarah J. Kurley, Rocío Domínguez-Vidaña et al. · 2021 · Cell
11. Network-based machine learning in colorectal and bladder organoid models predicts anti-cancer drug efficacy in patients
    JungHo Kong, Heetak Lee, Donghyo Kim, Seong Kyu Han, Doyeon Ha, Kunyoo Shin, Sanguk Kim · 2020 · Nature Communications
12. Identification of key biomarkers and immune infiltration in systemic lupus erythematosus by integrated bioinformatics analysis
    Xingwang Zhao, Longlong Zhang, Juan Wang, Min Zhang, Zhiqiang Song, Bing Ni, Yi You · 2021 · Journal of Translational Medicine
13. Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes
    Maria Fasolino, Gregory W. Schwartz, Abhijeet R. Patil, Aanchal Mongia, Maria L. Golson, Yue Julia Wang, Ashleigh R. Morgan, Chengyang Liu, Jonathan Schug, Jinping Liu et al. · 2022 · Nature Metabolism
14. Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape
    Martin, Constance J., Datta, Abhishek, Littlefield, Christopher, Kalra, Ashish, Chapron, Christopher, Wawersik, Stefan, Dagbay, Kevin B., Brueckner, Christopher T., Nikiforov, Anastasia, Danehy, Francis T. et al. · 2020 · Science Translational Medicine
15. Synergistic effects of common schizophrenia risk variants
    Nadine Schrode, Seok‐Man Ho, Kazuhiko Yamamuro, Amanda L. Dobbyn, Laura M. Huckins, Marliette R. Matos, Esther Cheng, P. J. Michael Deans, Erin K. Flaherty, Natalie Barretto et al. · 2019 · Nature Genetics
16. Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells
    Daniel Chauss, Tilo Freiwald, Reuben McGregor, Bingyu Yan, Luopin Wang, Estefanía Nova‐Lamperti, Dhaneshwar Kumar, Zonghao Zhang, Heather Teague, Erin E. West et al. · 2021 · Nature Immunology
17. Common genetic variation influencing human white matter microstructure
    Bingxin Zhao, Tengfei Li, Yue Yang, Xifeng Wang, Tianyou Luo, Yue Shan, Ziliang Zhu, Di Xiong, Mads E. Hauberg, Jaroslav M. Bendl et al. · 2021 · Science
18. Systems vaccinology: Probing humanity’s diverse immune systems with vaccines
    Bali Pulendran · 2014 · Proceedings of the National Academy of Sciences
19. Multi-trait analysis for genome-wide association study of five psychiatric disorders
    Yulu Wu, Hongbao Cao, Ancha V. Baranova, Hailiang Huang, Sheng Li, Lei Cai, Shuquan Rao, Minhan Dai, Min Xie, Yikai Dou et al. · 2020 · Translational Psychiatry
20. Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling
    Brian D. Robinson, Panagiotis J. Vlachostergios, Bhavneet Bhinder, Weisi Liu, Kailyn Li, Tyler J. Moss, Rohan Bareja, Kyung Park, Peyman Tavassoli, Joanna Cyrta et al. · 2019 · Nature Communications
21. Immune gene signatures for predicting durable clinical benefit of anti-PD-1 immunotherapy in patients with non-small cell lung cancer
    Hwang, Sohyun, Kwon, Ah-Young, Jeong, Ju-Yeon, Kim, Sewha, Kang, Haeyoun, Park, Joonsuk, Kim, Joo-Hang, Han, Ok Jin, Lim, Sun Min, An, Hee Jung · 2020 · Scientific Reports
22. Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease
    Chen, Yanhua, Du, Xiaomeng, Kuppa, Annapurna, Feitosa, Mary F., Bielak, Lawrence F., O’Connell, Jeffrey R., Musani, Solomon K., Guo, Xiuqing, Kahali, Bratati, Chen, Vincent L. et al. · 2023 · Nature Genetics
23. Altered Gene Expression along the Glycolysis–Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer
    Joanna M. Karasinska, James Thomas Topham, Steve E. Kalloger, Gun Ho Jang, Robert Edward Denroche, Luka Culibrk, Laura M. Williamson, Hui‐Li Wong, Michael K.C. Lee, Grainne Mary O'Kane et al. · 2019 · Clinical Cancer Research
24. Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy
    Hong, Xiaotong, Isern, Joan, Campanario, Silvia, Perdiguero, Eusebio, Ramírez-Pardo, Ignacio, Segalés, Jessica, Hernansanz-Agustín, Pablo, Curtabbi, Andrea, Deryagin, Oleg, Pollán, Angela et al. · 2022 · Cell stem cell
25. Machine learning and feature selection for drug response prediction in precision oncology applications
    Mehreen Ali, Tero A. Aittokallio · 2018 · Biophysical Reviews
26. SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways
    Yasser Majeed, Najeeb M. Halabi, Aisha Y. Madani, Rudolf Engelke, Aditya Mukund Bhagwat, Houari Abdesselem, Maha Victor Agha, Muneera Vakayil, Raphael J Courjaret, Neha Goswami et al. · 2021 · Scientific Reports
27. Chromatin regulatory mechanisms and therapeutic opportunities in cancer
    Alfredo M. Valencia, Cigall Kadoch · 2018 · Nature Cell Biology
28. Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade
    Tavi Nathanson, Arun Ahuja, Alex Rubinsteyn, Bülent Arman Aksoy, Matthew David Hellmann, Diana Miao, Eliezer M. Van Allen, Taha Merghoub, Jedd D. Wolchok, Alexandra Snyder et al. · 2016 · Cancer Immunology Research
29. Deep learning enables genetic analysis of the human thoracic aorta
    Pirruccello, James P., Chaffin, Mark D., Chou, Elizabeth L., Fleming, Stephen J., Lin, Honghuang, Nekoui, Mahan, Khurshid, Shaan, Friedman, Samuel F., Bick, Alexander G., Arduini, Alessandro et al. · 2022 · Nature Genetics
30. Intra-graft expression of genes involved in iron homeostasis predicts the development of operational tolerance in human liver transplantation
    Felix Bohne, Marc Martínez‐Llordella, Juan José Lozano, Rosa Miquel, Carlos Benítez, María‐Carlota Londoño, Tommaso Maria Manzia, Roberta Angelico, Dorine W. Swinkels, Harold Tjalsma et al. · 2011 · Journal of Clinical Investigation
31. exoRBase 2.0: an atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids
    Hongyan Lai, Yuchen Li, Hena Zhang, Jia Hu, Jiatao Liao, Ying Su, Qin Li, Bing Chen, Caiping Li, Zhen Wang et al. · 2021 · Nucleic Acids Research
32. Separate enrichment analysis of pathways for up- and downregulated genes
    Guini Hong, Wenjing Zhang, Hong‐Dong Li, Xiaopei Shen, Zheng Guo · 2013 · Journal of The Royal Society Interface
33. Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
    Elodie Persyn, Ken Benjamin Hanscombe, Joanna M. M. Howson, Cathryn M. Lewis, Matthew Traylor, Hugh Stephen Markus · 2020 · Nature Communications
34. Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial
    Sandra P. D’Angelo, Shailender Bhatia, Andrew Scott Brohl, Omid Hamid, Janice M. Mehnert, Patrick Andres Maximilian Terheyden, Kent C. Shih, Isaac Brownell, Célèste Lebbé, Karl D. Lewis et al. · 2020 · Journal for ImmunoTherapy of Cancer
35. TranSynergy: Mechanism-driven interpretable deep neural network for the synergistic prediction and pathway deconvolution of drug combinations
    Qiao Liu, Lei Xie · 2021 · PLoS Computational Biology
36. Biomarkers Associated With Response to Regorafenib in Patients With Hepatocellular Carcinoma
    Michael Teufel, Henrik Seidel, Karl Köchert, Gerold Meinhardt, Richard S. Finn, Josep Maria Llovet, Jordi Bruix · 2019 · Gastroenterology
37. Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery
    Natalie Boehnke, Joelle P. Straehla, Hannah C. Safford, Mustafa Kocak, Matthew G. Rees, Melissa M. Ronan, Danny Rosenberg, Charles H. Adelmann, Raghu R. Chivukula, Namita Nabar et al. · 2022 · Science
38. Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes
    Li Zhang, Kenzie D. MacIsaac, Ting Zhou, Pei‐Yu Huang, Chunlin Xin, Jason R. Dobson, Kun Yu, Derek Y. Chiang, Yue Fan, Marc R. Pelletier et al. · 2017 · Molecular Cancer Research
39. i-cisTarget 2015 update: generalized cis-regulatory enrichment analysis in human, mouse and fly
    Imrichová, Hana, Hulselmans, Gert, Kalender Atak, Zeynep, Potier, Delphine, Aerts, Stein · 2015 · Nucleic Acids Research
40. Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments
    Noëlla Lopes, Claire McIntyre, Stefania Martin, Mathilde Raverdeau, Nital Sumaria, Ayano C. Kohlgruber, Gina J. Fiala, Leandro Z. Agudelo, Lydia Dyck, Harry Kane et al. · 2021 · Nature Immunology
41. Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression
    Wu, Steven J., Furlan, Scott N., Mihalas, Anca B., Kaya-Okur, Hatice S., Feroze, Abdullah H., Emerson, Samuel N., Zheng, Ye, Carson, Kalee, Cimino, Patrick J., Keene, C. Dirk et al. · 2021 · Nature Biotechnology
42. Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure
    Chen, Xianwei, Sun, Guoqiang, Tian, E, Zhang, Mingzi, Davtyan, Hayk, Beach, Thomas G., Reiman, Eric M., Blurton‐Jones, Mathew, Holtzman, David M., Shi, Yanhong · 2021 · Advanced Science
43. Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions
    Daniel Butler, Christopher Mozsary, Cem Meydan, Jonathan Foox, Joel A. Rosiene, Alon Shaiber, David Danko, Ebrahim Afshinnekoo, Matthew J. MacKay, Fritz Joachim Sedlazeck et al. · 2021 · Nature Communications
44. Learning functional properties of proteins with language models
    Serbülent Ünsal, Heval Ataş, Muammer Albayrak, Kemal Turhan, Aybar C. Acar, Tunca Doğan · 2022 · Nature Machine Intelligence
45. Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer
    Luz García‐Alonso, Francesco Iorio, Angela Matchan, Nuno A. Fonseca, Patricia Jaaks, Gareth Peat, Miguel Pignatelli, Fiammetta Falcone, Cyril H. Benes, Ian Dunham et al. · 2017 · Cancer Research
46. Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia
    Michael Y. Choi, George F. Widhopf, Emanuela M. Ghia, Reilly L. Kidwell, Md Kamrul Hasan, Jian Yu, Laura Z. Rassenti, Liguang Chen, Yun Chen, Emily I. Pittman et al. · 2018 · Cell stem cell
47. Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map
    Ian C. P. Smith, Peyton Greenside, Ted E. Natoli, David L. Lahr, David Wadden, Itay Tirosh, Rajiv Narayan, David E. Root, Todd R. Golub, Aravind Subramanian et al. · 2017 · PLoS Biology
48. Multiomic Analysis of Lung Tumors Defines Pathways Activated in Neuroendocrine Transformation
    Alvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian Ada Zhan, Maysun Hasan, Shweta S. Chavan, Fanli Meng, Fathema Uddin, Parvathy Manoj, Mark T.A. Donoghue, Helen H. Won et al. · 2021 · Cancer Discovery
49. RNA profiles reveal signatures of future health and disease in pregnancy
    Morten Rasmussen, Mitsu Reddy, Rory Nolan, Joan Camuñas-Soler, Arkady B. Khodursky, Nikolai Madrid Scheller, David E. Cantonwine, Line Engelbrechtsen, Jia Dai Mi, Arup Dutta et al. · 2022 · Nature
50. Advancing Computational Toxicology by Interpretable Machine Learning
    Xuelian Jia, Tong Wang, Hao Zhu · 2023 · Environmental Science & Technology
51. Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures
    Zhengyan Kan, Ying Ding, Jin-Ho Kim, Hae Hyun Jung, Woosung Chung, Samir Lal, Soonweng Cho, Julio Fernandez-Banet, Se Kyung Lee, Seok Won Kim et al. · 2018 · Nature Communications
52. Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
    Josepmaria Argemí, Maria Ujue Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica L. Massey, Joel P. Gue, Joaquín Cabezas, Juan José Lozano, Derek Van Booven, Aaron W. Bell et al. · 2019 · Nature Communications
53. High-Throughput Transcriptomics Platform for Screening Environmental Chemicals
    Joshua Harrill, Logan J. Everett, Derik E. Haggard, Thomas Y. Sheffield, Joseph L. Bundy, Clinton M. Willis, Russell S. Thomas, Imran Shah, Richard Judson · 2021 · Toxicological Sciences
54. High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification
    Siel Olbrecht, Pieter Busschaert, Junbin Qian, Adriaan Vanderstichele, Liselore Loverix, Toon Van Gorp, Els Van Nieuwenhuysen, Sileny Han, Annick Van den Broeck, An Coosemans et al. · 2021 · Genome Medicine
55. QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
    Zhicong Zhao, Ying Qing, Lei Dong, Li Han, Dong Wu, Yangchan Li, Wei Li, Jianhuang Xue, Keren Zhou, Miao Sun et al. · 2023 · Cell
56. A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat
    Xu, Rong, Wang, QuanQiu, Li, Li · 2015 · BMC Genomics
57. Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity
    Anthony Richard Cillo, Carly Cardello, Feng Shan, Lilit Karapetyan, Sheryl R. Kunning, Cindy Sander, Elizabeth A. Rush, Arivarasan D. Karunamurthy, Ryan Campbell Massa, Anjali Rohatgi et al. · 2024 · Cell
58. A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma
    Amitabh Sharma, Jörg Menche, Chaohua Huang, Tatiana Ort, Xiaobo Zhou, Maksim Kitsak, Nidhi Sahni, Derek M. Thibault, Linh Voung, Feng Guo et al. · 2015 · Human Molecular Genetics
59. Structural covariance networks are coupled to expression of genes enriched in supragranular layers of the human cortex
    Rafael Romero-García, Kirstie Jane Whitaker, František Váša, Jakob Seidlitz, Maxwell Shinn, Peter Fonagy, Raymond J. Dolan, Peter Brian Jones, Ian Michael Goodyer, Edward Thomas Bullmore et al. · 2017 · NeuroImage
60. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
    Zhe Zhu, Pinar Mesci, Jean A. Bernatchez, Ryan C. Gimple, Xiuxing Wang, Simon T. Schafer, Hiromi Inoue Wettersten, Sungjun Beck, Alex E. Clark, Qiulian Wu et al. · 2020 · Cell stem cell
61. MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis
    Chien‐Kuang Cornelia Ding, Joshua Rose, Tianai Sun, Jianli Wu, Po‐Han Chen, Chao‐Chieh Lin, Wen‐Hsuan Yang, Kai‐Yuan Chen, Hana Lee, Emily Xu et al. · 2020 · Nature Metabolism
62. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
    PDXNET Consortium, Woo, Xing Yi, EurOPDX Consortium, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W., de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh et al. · 2021 · Nature Genetics
63. Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability
    Sònia Guedan, Aviv Madar, Victoria Casado‐Medrano, Carolyn E. Shaw, Anna Wing, Fang Liu, Regina M. Young, Carl H. June, Avery D. Posey · 2020 · Journal of Clinical Investigation
64. Circadian Entrainment Triggers Maturation of Human In Vitro Islets
    Alvarez-Dominguez, Juan R., Donaghey, Julie, Rasouli, Niloofar, Kenty, Jennifer H.R., Helman, Aharon, Charlton, Jocelyn, Straubhaar, Juerg R., Meissner, Alexander, Melton, Douglas A. · 2020 · Cell Stem Cell
65. Estimating Sample-Specific Regulatory Networks
    Marieke L. Kuijjer, Matthew G. Tung, Guo‐Cheng Yuan, John F Quackenbush, Kimberly Glass · 2018 · iScience
66. Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells
    Amina Iftekhar, Hilmar Berger, Nassim Bouznad, Julian Heuberger, Francesco Boccellato, Ulrich Dobrindt, Heiko Hermeking, Michael J. Sigal, Thomas F. Meyer · 2021 · Nature Communications
67. Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
    Nicolò Bancaro, Bianca Calì, Martina Troiani, Angela Rita Elia, Rydell Alvarez Arzola, Giuseppe Attanasio, Ping Lai, Mateus Crespo, Bora Gürel, Rita Pereira et al. · 2023 · Cancer Cell
68. Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing
    Mostafavi, S, Battle, A, Zhu, X, Potash, J B, Weissman, M M, Shi, J, Beckman, K, Haudenschild, C, McCormick, C, Mei, R et al. · 2014 · Molecular Psychiatry
69. Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
    Julia Bergild McBrien, Maud Mavigner, Lavinia Franchitti, S. Abigail Smith, Erick White, Gregory K. Tharp, Hasse Walum, Kathleen Busman‐Sahay, Christian R. Aguilera-Sandoval, William O. Thayer et al. · 2020 · Nature
70. Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels
    Tobias Roider, Julian Seufert, Alexey Uvarovskii, Felix Frauhammer, Marie Bordas, Nima Abedpour, Marta Stolarczyk, Jan‐Philipp Mallm, Sophie A. Herbst, Peter‐Martin Bruch et al. · 2020 · Nature Cell Biology
71. Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
    Wang, Minghui, Li, Aiqun, Sekiya, Michiko, Beckmann, Noam D., Quan, Xiuming, Schrode, Nadine, Fernando, Michael B., Yu, Alex, Zhu, Li, Cao, Jiqing et al. · 2021 · Neuron
72. Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis
    Guccini, Ilaria, Revandkar, Ajinkya, D'Ambrosio, Mariantonietta, Colucci, Manuel, Pasquini, Emiliano, Mosole, Simone, Troiani, Martina, Brina, Daniela, Sheibani-Tezerji, Raheleh, Elia, Angela Rita et al. · 2021 · Cancer Cell
73. CD3 bispecific antibody–induced cytokine release is dispensable for cytotoxic T cell activity
    Ji Li, Robert Piskol, Ryan Ybarra, Ying-Jiun J. Chen, Jason Li, Dionysos Slaga, Maria L. Hristopoulos, Robyn Clark, Zora D. Modrusan, Klára Tótpál et al. · 2019 · Science Translational Medicine
74. Potassium channel dysfunction in human neuronal models of Angelman syndrome
    Alfred Xuyang Sun, Qiang Yuan, Masahiro Fukuda, Weonjin Yu, Hai Yan, Grace Gui Yin Lim, Mui Hoon Nai, Giuseppe Alessandro D’Agostino, Hoang-Dai Tran, Yoko Itahana et al. · 2019 · Science
75. Human brain organoids assemble functionally integrated bilateral optic vesicles
    Elke Gabriel, Walid Albanna, Giovanni Pasquini, Anand Ramani, Nataša Josipović, Aruljothi Mariappan, Friedrich Schinzel, Celeste M M. Karch, Guobin Bao, Marco Gottardo et al. · 2021 · Cell stem cell
76. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes
    Valeria Visconte, Heesun Joyce Rogers, Jarnail Singh, John Barnard, Manoj Bupathi, Fabı́ola Traina, James T. McMahon, Hideki Makishima, Hadrian Szpurka, Anna Malgorzata Jankowska et al. · 2012 · Blood
77. Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system
    Sebastian Schuth, Solange Le Blanc, Teresa G. Krieger, Julia Jabs, Miriam Schenk, Nathalia A. Giese, Markus Wolfgang Büchler, Roland Eils, Christian Conrad, Oliver Strobel · 2022 · Journal of Experimental & Clinical Cancer Research
78. Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
    Chiara Cianciaruso, Tim Beltraminelli, Florent Duval, Sina Nassiri, Romain Hamelin, André Mozes, Héctor Gallart‐Ayala, Gerardo Ceada, Bruno Torchia, Carola Hermine Ries et al. · 2019 · Cell Reports
79. γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis
    Hu, Bo, Jin, Chengcheng, Zeng, Xing, Resch, Jon M., Jedrychowski, Mark P., Yang, Zongfang, Desai, Bhavna N., Banks, Alexander S., Lowell, Bradford B., Mathis, Diane et al. · 2020 · Nature
80. Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
    Carmen M. Anadon, Xiaoqing Yu, Kay Hänggi, Subir Biswas, Ricardo A. Chaurio, Alexandra Martin, Kyle K. Payne, Gunjan Mandal, Patrick Innamarato, Carly M. Harro et al. · 2022 · Cancer Cell
81. Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer
    Peipei Zhou, Hao Shi, Hongling Huang, Xiang Sun, Sujing Yuan, Nicole M. Chapman, Jon P. Connelly, Seon Ah Lim, Jordy Saravia, Anil KC et al. · 2023 · Nature
82. A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren’s Syndrome
    Katherine James, Shereen Al-Ali, Jessica R. Tarn, Simon Cockell, Colin S. Gillespie, Victoria Hindmarsh, James Locke, Sheryl Mitchell, Dennis William Lendrem, Simon Bowman et al. · 2015 · PLoS ONE
83. Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity
    Daniel Francis Ditoro, Stacey N. Harbour, Jennifer K. Bando, Gloria A. Benavides, Steven J. Witte, Vincent A. Laufer, Carson E. Moseley, Jeffery R. Singer, Blake F. Frey, Henrietta Turner et al. · 2020 · Immunity
84. A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer
    Frederick Hugh Wilson, Cory M. Johannessen, Federica Piccioni, Pablo Tamayo, Jong Wook Kim, Eliezer M. Van Allen, Steven M. Corsello, Marzia Capelletti, Antonio Calles, Mohit Butaney et al. · 2015 · Cancer Cell
85. Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling
    Caleb A. Dawson, Bhupinder Pal, François Vaillant, Luke C. Gandolfo, Zhaoyuan Liu, Camille Blériot, Florent Ginhoux, Gordon K. Smyth, Geoffrey John Lindeman, Scott N. Mueller et al. · 2020 · Nature Cell Biology
86. CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection
    Yu-Jung Lu, Palmira Barreira‐Silva, Shayla Boyce, Jennifer Powers, Kelly Cavallo, Samuel M. Behar · 2021 · Cell Reports
87. Towards understanding brain-gut-microbiome connections in Alzheimer’s disease
    Xu, Rong, Wang, QuanQiu · 2016 · BMC Systems Biology
88. Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress
    Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli, Kelli M. Wilson, Yang Zhang, Erin Beck, Linda C. Sciuto et al. · 2021 · Cancer Cell
89. Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action
    McFarland, James M., Paolella, Brenton R., Warren, Allison, Geiger-Schuller, Kathryn, Shibue, Tsukasa, Rothberg, Michael, Kuksenko, Olena, Colgan, William N., Jones, Andrew, Chambers, Emily et al. · 2020 · Nature Communications
90. AIM2 in regulatory T cells restrains autoimmune diseases
    Wei-Chun Chou, Zengli Guo, Hao Guo, Liang Chen, Ge Zhang, Kaixin Liang, Ling Xie, Xianming M. Tan, Sara A. Gibson, Elena Rampanelli et al. · 2021 · Nature
91. Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment
    Shiya Cheng, Gerrit Altmeppen, Chun So, Luisa M. Welp, Sarah Mae U. Penir, Torben Ruhwedel, Katerina Menelaou, Katarina Harasimov, Alexandra Stützer, Martyn L Blayney et al. · 2022 · Science
92. Heterogeneous Network Edge Prediction: A Data Integration Approach to Prioritize Disease-Associated Genes
    Himmelstein, Daniel S., Baranzini, Sergio E. · 2015 · PLOS Computational Biology
93. Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package
    Nurcan Tunçbağ, Sara J.C. Gosline, Amanda J. Kedaigle, Anthony R. Soltis, Anthony Gitter, Ernest Fraenkel · 2016 · PLoS Computational Biology
94. An Attention-based Collaboration Framework for Multi-View Network Representation Learning
    Meng Qu, Jian Tang, Jingbo Shang, Xiang Ren, Ming Zhang, Jiawei Han · 2017 · ACM International Conference on Information and Knowledge Management (CIKM)
95. Identification of shared and disease-specific host gene–microbiome associations across human diseases using multi-omic integration
    Sambhawa Priya, Michael B. Burns, Tonya Ward, Ruben A. T. Mars, Elizabeth M. Adamowicz, Eric F. Lock, Purna Kashyap, Dan Knights, Ran Blekhman · 2022 · Nature Microbiology
96. Hundreds of genes experienced convergent shifts in selective pressure in marine mammals
    Chikina, Maria, Robinson, Joseph D., Clark, Nathan L. · 2016 · Molecular Biology and Evolution
97. multiGSEA: a GSEA-based pathway enrichment analysis for multi-omics data
    2020
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