Molecular signatures database (MSigDB) 3.0

Cited by (1,039)

Items 101–200 of 1,039

1. Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
   Yi Zhou, Mingjian Fei, Gu Zhang, Wei‐Ching Liang, WeiYu Lin, Yan Wu, Robert Piskol, John Brady Ridgway, Erin McNamara, Haochu Huang et al. · 2020 · Immunity
2. Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact
   da Silveira, Willian A., Fazelinia, Hossein, Rosenthal, Sara Brin, Laiakis, Evagelia C., Kim, Man S., Meydan, Cem, Kidane, Yared, Rathi, Komal S., Smith, Scott M., Stear, Benjamin et al. · 2020 · Cell
3. GeneMANIA Prediction Server 2013 Update
   Zuberi, Khalid, Franz, Max, Rodriguez, Harold, Montojo, Jason, Lopes, Christian Tannus, Bader, Gary D., Morris, Quaid · 2013 · Nucleic Acids Research
4. Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
   Nemanja Despot Marjanovic, Matan Hofree, Jason Earl Chan, David A. Canner, Katherine Wu, Marianna Trakala, Griffin G. Hartmann, Olivia C. Ghirardelli Smith, Jonathan Y. Kim, Kelly V. Evans et al. · 2020 · Cancer Cell
5. The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
   Makoto Kurachi, R. Anthony Barnitz, Nir Yosef, Pamela M. Odorizzi, Michael A. DiIorio, Madeleine E. Lemieux, Kathleen B. Yates, Jernej Godec, Martin G. Klatt, Aviv Regev et al. · 2014 · Nature Immunology
6. B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma
   Johannes Griss, Wolfgang Michael Bauer, Christine Wagner, Martin Simon, Minyi Chen, Katharina Grabmeier‐Pfistershammer, Margarita Maurer‐Granofszky, Florian Roka, Thomas Penz, Christoph Bock et al. · 2019 · Nature Communications
7. Integrated intra‐ and intercellular signaling knowledge for multicellular omics analysis
   Dénes Türei, Alberto Valdeolivas, Lejla Gul, Nicolàs Palacio‐Escat, Michal Klein, Olga Ivanova, Marton L. Olbei, Attila Gábor, Fabian Joachim Theis, Dezső Módos et al. · 2021 · Molecular Systems Biology
8. Hypoxia induces rapid changes to histone methylation and reprograms chromatin
   Batie, Michael, Frost, Julianty, Frost, Mark, Wilson, James W., Schofield, Pieta, Rocha, Sonia · 2019 · Science
9. A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions
   Jarada, Tamer N., Rokne, Jon G., Alhajj, Reda · 2020 · Journal of Cheminformatics
10. Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins
    Maomao Zhang, Julie S. Di Martino, Robert L. Bowman, Nathaniel R. Campbell, Sanjeethan C. Baksh, Theresa Simon-Vermot, Isabella S. Kim, Pearce B. Haldeman, Chandrani Mondal, Vladimir Yong-Gonzales et al. · 2018 · Cancer Discovery
11. Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells
    Hogrebe, Nathaniel J., Augsornworawat, Punn, Maxwell, Kristina G., Velazco-Cruz, Leonardo, Millman, Jeffrey R. · 2020 · Nature Biotechnology
12. Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity
    Duong, Ellen, Fessenden, Tim B., Lutz, Emi, Dinter, Teresa, Yim, Leon, Blatt, Sarah, Bhutkar, Arjun, Wittrup, Karl Dane, Spranger, Stefani · 2022 · Immunity
13. A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra
    Gervaise H. Henry, Alicia Malewska, Diya Binoy Joseph, Venkat S. Malladi, Jeon Lee, Jose R. Torrealba, Ryan J. Mauck, Jeffrey C. Gahan, Ganesh V. Raj, Claus G. Roehrborn et al. · 2018 · Cell Reports
14. Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
    Griffin, Gabriel K., Wu, Jingyi, Iracheta-Vellve, Arvin, Patti, James C., Hsu, Jeffrey, Davis, Thomas, Dele-Oni, Deborah, Du, Peter P., Halawi, Aya G., Ishizuka, Jeffrey J. et al. · 2021 · Nature
15. From cohorts to molecules: adverse impacts of endocrine disrupting mixtures
    Caporale, Nicolò, Leemans, Michelle, Birgersson, Lina, Germain, Pierre-Luc, Cheroni, Cristina, Borbély, Gábor, Engdahl, Elin, Lindh, Christian, Bressan, Raul Bardini, Cavallo, Francesca et al. · 2022 · Science
16. Immune checkpoint HLA-E:CD94-NKG2A mediates evasion of circulating tumor cells from NK cell surveillance
    Xiaowei Liu, Jinen Song, Hao Zhang, Xinyu Liu, Fengli Zuo, Yunuo Zhao, Yujie Zhao, Xiaomeng Yin, Xinyu Guo, Xi Lawrence Wu et al. · 2023 · Cancer Cell
17. Defining the biological basis of radiomic phenotypes in lung cancer
    Grossmann, Patrick, Stringfield, Olya, El-Hachem, Nehme, Bui, Marilyn M, Rios Velazquez, Emmanuel, Parmar, Chintan, Leijenaar, Ralph TH, Haibe-Kains, Benjamin, Lambin, Philippe, Gillies, Robert J et al. · 2017 · eLife
18. Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming
    Ralph Stadhouders, Enrique Vidal, François Serra, Bruno Di Stefano, François Le Dily, Javier Quilez, Antonio Gómez, Samuel Collombet, Clara Berenguer, Yasmina Cuartero et al. · 2018 · Nature Genetics
19. Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy
    Yamazaki, Takahiro, Kirchmair, Alexander, Sato, Ai, Buqué, Aitziber, Rybstein, Marissa, Petroni, Giulia, Bloy, Norma, Finotello, Francesca, Stafford, Lena, Navarro Manzano, Esther et al. · 2020 · Nature Immunology
20. Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma
    Kwong, Lawrence N, Costello, James C, Liu, Huiyun, Jiang, Shan, Helms, Timothy L, Langsdorf, Aliete E, Jakubosky, David, Genovese, Giannicola, Muller, Florian L, Jeong, Joseph H et al. · 2012 · Nature Medicine
21. Oxytocin pathway gene networks in the human brain
    Quintana, Daniel S., Rokicki, Jaroslav, van der Meer, Dennis, Alnæs, Dag, Kaufmann, Tobias, Córdova-Palomera, Aldo, Dieset, Ingrid, Andreassen, Ole A., Westlye, Lars T. · 2019 · Nature Communications
22. PINA v2.0: mining interactome modules
    Mark J. Cowley, Mark Pinese, Karin S. Kassahn, Nicola Waddell, John V. Pearson, Sean Michael Grimmond, Andrew Victor Biankin, Sampsa Hautaniemi, Jianmin Wu · 2011 · Nucleic Acids Research
23. METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
    Rui Jun Su, Lei Dong, Yangchan Li, Min Gao, P. Cody He, Wei Liu, Jiangbo Wei, Zhicong Zhao, Lei Gao, Li Han et al. · 2022 · Nature Cell Biology
24. Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis
    Alexandra Snyder, Tavi Nathanson, Samuel Aaron Funt, Arun Ahuja, Jacqueline L. Buros, Matthew David Hellmann, Eliza Chang, Bülent Arman Aksoy, Hikmat A Al‐Ahmadie, Erik C. Yusko et al. · 2017 · PLoS Medicine
25. Chemical Similarity Enrichment Analysis (ChemRICH) as alternative to biochemical pathway mapping for metabolomic datasets
    Dinesh Kumar Barupal, Oliver Fiehn · 2017 · Scientific Reports
26. Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
    Alessandra De Leo, Alessio Ugolini, Xiaoqing Yu, Fabio Scirocchi, Delia Scocozza, Bárbara Peixoto, Angelica Pace, Luca D’Angelo, James K. Liu, Arnold B. Etame et al. · 2024 · Immunity
27. A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy
    Julie S. Di Martino, Ana Rita Nobre, Chandrani Mondal, Isra N. Taha, Eduardo Farias, Elana Judith Fertig, Alexandra Naba, Julio A. Aguirre‐Ghiso, Jose Javier Bravo‐Cordero · 2021 · Nature Cancer
28. A Curated Resource for Phosphosite-specific Signature Analysis
    Karsten Krug, Philipp Mertins, Bin Zhang, Peter V. Hornbeck, Rajesh Raju, Rushdy Ahmad, Matthew J. Szucs, Filip Mundt, Dominique Forestier, Judit Jané‐Valbuena et al. · 2018 · Molecular & Cellular Proteomics
29. The SARS-CoV-2 RNA–protein interactome in infected human cells
    Schmidt, Nora, Lareau, Caleb A., Keshishian, Hasmik, Ganskih, Sabina, Schneider, Cornelius, Hennig, Thomas, Melanson, Randy, Werner, Simone, Wei, Yuanjie, Zimmer, Matthias et al. · 2020 · Nature Microbiology
30. Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans
    Thrupp, Nicola, Sala Frigerio, Carlo, Wolfs, Leen, Skene, Nathan G., Fattorelli, Nicola, Poovathingal, Suresh, Fourne, Yannick, Matthews, Paul M., Theys, Tom, Mancuso, Renzo et al. · 2020 · Cell Reports
31. Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts
    Jeffrey J. Quinn, Matthew G. Jones, Ross A. Okimoto, Shigeki Nanjo, Michelle M. Chan, Nir Yosef, Trever Grant Bivona, Jonathan S. Weissman · 2021 · Science
32. Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.
    Karlsson Linnér, Richard, Mallard, Travis T., Barr, Peter B., Sanchez-Roige, Sandra, Madole, James W., Driver, Morgan N., Poore, Holly E., de Vlaming, Ronald, Grotzinger, Andrew D., Tielbeek, Jorim J. et al. · 2021 · Nature Neuroscience
33. Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer
    Petralia, Francesca, Tignor, Nicole, Reva, Boris, Koptyra, Mateusz, Chowdhury, Shrabanti, Rykunov, Dmitry, Krek, Azra, Ma, Weiping, Zhu, Yuankun, Ji, Jiayi et al. · 2020 · Cell
34. Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma
    Cindy Neuzillet, Annemilaï Tijeras‐Raballand, Chanthirika Ragulan, Jerome F. Cros, Yatish Patil, Matthieu Martinet, Mert Erkan, Jorg H. Kleeff, Jeremy S. Wilson, Minoti Vivek Apte et al. · 2018 · The Journal of Pathology
35. IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases
    Yang Zhao, Jiangqing Chen, Massimo Andreatta, Bing Feng, Yuqing Xie, Mathias Wenes, Yi Wang, Min Gao, Xiaomeng Hu, Pedro J. Romero et al. · 2024 · Nature Biotechnology
36. Molecular High-Grade B-Cell Lymphoma: Defining a Poor-Risk Group That Requires Different Approaches to Therapy
    Chulin Sha, Sharon Barrans, Francesco Cucco, Michael A. Bentley, Matthew A. Care, Thomas Cummin, Hannah Kennedy, Joe Sneath Thompson, Rahman Uddin, Lisa J. Worrillow et al. · 2018 · Journal of Clinical Oncology
37. Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome
    Chao Yang, Jason Siebert, Robert Burns, Zachary J. Gerbec, Benedetta B. Bonacci, Amy L. Rymaszewski, Mary J. Rau, Matthew John Riese, Sridhar Rao, Karen-Sue Carlson et al. · 2019 · Nature Communications
38. Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma
    Smith, Christof C., Beckermann, Kathryn E., Bortone, Dante S., De Cubas, Aguirre A., Bixby, Lisa M., Lee, Samuel J., Panda, Anshuman, Ganesan, Shridar, Bhanot, Gyan, Wallen, Eric M. et al. · 2018 · Journal of Clinical Investigation
39. Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
    Zhang, Martin Jinye, Hou, Kangcheng, Dey, Kushal K., Sakaue, Saori, Jagadeesh, Karthik A., Weinand, Kathryn, Taychameekiatchai, Aris, Rao, Poorvi, Pisco, Angela Oliveira, Zou, James et al. · 2022 · Nature Genetics
40. Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
    Jonggeol Jeffrey Kim, Dan Vitale, Diego Véliz Otani, Michelle Mulan Lian, Karl Heilbron, Stella W. Aslibekyan, Adam Auton, Elizabeth Babalola, Robert K. Bell, Jessica Bielenberg et al. · 2023 · Nature Genetics
41. Resolving host–pathogen interactions by dual RNA-seq
    Alexander J. Westermann, Lars Barquist, Jörg Vogel · 2017 · PLoS Pathogens
42. Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour
    Jones, Samuel E., van Hees, Vincent T., Mazzotti, Diego R., Marques-Vidal, Pedro, Sabia, Séverine, van der Spek, Ashley, Dashti, Hassan S., Engmann, Jorgen, Kocevska, Desana, Tyrrell, Jessica et al. · 2019 · Nature Communications
43. Integrated cross-study datasets of genetic dependencies in cancer
    Clare Pacini, Joshua M. Dempster, Isabella Boyle, Emanuel Gonçalves, Hanna Najgebauer, Emre Karakoç, Dieudonne J. van der Meer, Andrew S. Barthorpe, Howard W. Lightfoot, Patricia Jaaks et al. · 2021 · Nature Communications
44. Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits
    Zhao, Bingxin, Luo, Tianyou, Li, Tengfei, Li, Yun, Zhang, Jingwen, Shan, Yue, Wang, Xifeng, Yang, Liuqing, Zhou, Fan, Zhu, Ziliang et al. · 2019 · Nature Genetics
45. p21 produces a bioactive secretome that places stressed cells under immunosurveillance
    Sturmlechner, Ines, Zhang, Cheng, Sine, Chance C., van Deursen, Erik-Jan, Jeganathan, Karthik B., Hamada, Naomi, Grasic, Jan, Friedman, David, Stutchman, Jeremy T., Can, Ismail et al. · 2021 · Science
46. Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation
    Jernej Godec, Yan Qin Tan, Arthur Liberzon, Pablo Tamayo, Sanchita Bhattacharya, Atul Janardhan Butte, Jill P. Mesirov, W. Nicholas Haining · 2016 · Immunity
47. Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
    Miranda V. Hunter, Reuben M. Moncada, Joshua M. Weiss, Itai Yanai, Richard Mark White · 2021 · Nature Communications
48. TGF-β upregulates miR-181a expression to promote breast cancer metastasis
    Molly A. Taylor, Khalid Sossey‐Alaoui, Cheryl L. Thompson, David Danielpour, William P. Schiemann · 2012 · Journal of Clinical Investigation
49. Systematic Evaluation of Molecular Networks for Discovery of Disease Genes
    Huang, Justin K., Carlin, Daniel E., Yu, Michael Ku, Zhang, Wei, Kreisberg, Jason F., Tamayo, Pablo, Ideker, Trey · 2018 · Cell Systems
50. Tau Activation of Microglial cGAS–IFN Reduces MEF2C‐mediated Cognitive Resilience
    Udeochu, Joe C., Amin, Sadaf, Huang, Yige, Fan, Li, Torres, Eileen Ruth S., Carling, Gillian K., Liu, Bangyan, McGurran, Hugo, Coronas-Samano, Guillermo, Kauwe, Grant et al. · 2023 · Nature Neuroscience
51. Computational deconvolution: extracting cell type-specific information from heterogeneous samples
    Shai S. Shen-Orr, Renaud Gaujoux · 2013 · Current Opinion in Immunology
52. Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms
    Sheng Xiao, Nir Yosef, Jianfei Yang, Yonghui Wang, Ling Zhou, Chen Ying Zhu, Chuan Wu, Erkan Baloglu, Darby R. Schmidt, Radha Ramesh et al. · 2014 · Immunity
53. Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition
    Yael Cohen‐Sharir, James M. McFarland, Mai Abdusamad, Carolyn Marquis, Sara Vanessa Bernhard, Mariya Kazachkova, Helen Tang, Marica Rosaria Ippolito, Kathrin Laue, Johanna Zerbib et al. · 2021 · Nature
54. Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control
    Hannah Priyadarshini Gideon, Travis K. Hughes, Constantine N. Tzouanas, Marc H. Wadsworth, Ang Andy Tu, Todd M. Gierahn, Joshua M. Peters, Forrest F. Hopkins, Jun-Rong Wei, Conner Kummerlowe et al. · 2022 · Immunity
55. Convolutional neural network models for cancer type prediction based on gene expression
    Milad Mostavi, Yu‐Chiao Chiu, Yufei Huang, Yidong Chen · 2020 · BMC Medical Genomics
56. Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis
    Anissa Anindya Widjaja, Brijesh Kumar Singh, Eleonora Adami, Sivakumar Viswanathan, Jinrui Dong, Giuseppe Alessandro D’Agostino, Benjamin Ng, Wei‐Wen Lim, Jessie Tan, Bhairav Suryakant Paleja et al. · 2019 · Gastroenterology
57. Quantifying genetic effects on disease mediated by assayed gene expression levels
    Douglas W. Yao, Luke Jen O’Connor, Alkes L. Price, Alexander Gusev · 2020 · Nature Genetics
58. Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling
    Lucas A. Salas, Ze Zhang, Devin C. Koestler, Rondi A. Butler, Helen M. Hansen, Annette M. Molinaro, John K. Wiencke, Karl T. Kelsey, Brock C. Christensen · 2022 · Nature Communications
59. ImmGen report: sexual dimorphism in the immune system transcriptome
    Gal-Oz, Shani Talia, Maier, Barbara, Yoshida, Hideyuki, Seddu, Kumba, Elbaz, Nitzan, Czysz, Charles, Zuk, Or, Stranger, Barbara E., Ner-Gaon, Hadas, Shay, Tal · 2019 · Nature Communications
60. Myocardial infarction accelerates breast cancer via innate immune reprogramming
    Graeme J. Koelwyn, Alexandra A. C. Newman, Milessa Silva Afonso, Coen V Solingen, Emma M. Corr, Emily J. Brown, Kathleen B. Albers, Naoko Yamaguchi, Deven Narke, Martin Schlegel et al. · 2020 · Nature Medicine
61. Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm
    Philip A. Mudd, Jeremy Chase Crawford, Jackson S. Turner, Aisha Hegab Souquette, Daniel Reynolds, Diane E. Bender, James Percival Bosanquet, Nitin J. Anand, David A. Striker, R. Scott Martin et al. · 2020 · Science Advances
62. Computational genomics tools for dissecting tumour–immune cell interactions
    Hubert Hackl, Pornpimol Charoentong, Francesca Finotello, Zlatko Trajanoski · 2016 · Nature Reviews Genetics
63. A graph neural network model to estimate cell-wise metabolic flux using single-cell RNA-seq data
    Norah Alghamdi, Wennan Chang, Pengtao Dang, Xiaoyu Lu, Changlin Wan, Silpa Gampala, Zhi Huang, Jiashi Wang, Qin Ma, Yong Zang et al. · 2021 · Genome Research
64. Resolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis
    Boland, Michelle L., Laker, Rhianna C., Mather, Karly, Nawrocki, Arkadiusz, Oldham, Stephanie, Boland, Brandon B., Lewis, Hilary, Conway, James, Naylor, Jacqueline, Guionaud, Silvia et al. · 2020 · Nature Metabolism
65. Quantitative set analysis for gene expression: a method to quantify gene set differential expression including gene-gene correlations
    Gur Yaari, Christopher R. Bolen, Juilee Thakar, Steven H. Kleinstein · 2013 · Nucleic Acids Research
66. Integrative analysis of genomic and transcriptomic characteristics associated with progression of aggressive thyroid cancer
    Seong‐Keun Yoo, Young Shin Song, Eun Kyung Lee, Jinha Hwang, Hwan Hee Kim, Gyeongseo Jung, Young A Kim, Su‐jin Kim, Sun Wook Cho, Jae‐Kyung Won et al. · 2019 · Nature Communications
67. Creation of bladder assembloids mimicking tissue regeneration and cancer
    Eunjee Kim, Seoyoung Choi, Byunghee Kang, JungHo Kong, Yubin Kim, Woong Yoon, Hwa Rim Lee, Sung Eun Kim, Hyo‐Min Kim, Hye Sun Lee et al. · 2020 · Nature
68. Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy
    Alyssa Sheih, Valentin Voillet, Laïla‐Aïcha Hanafi, Hannah A. DeBerg, Masanao Yajima, Reed M. Hawkins, Vivian H. Gersuk, Stanley R. Riddell, David G. Maloney, Martin E. Wohlfahrt et al. · 2020 · Nature Communications
69. Hotspot identifies informative gene modules across modalities of single-cell genomics
    DeTomaso, David, Yosef, Nir · 2021 · Cell Systems
70. Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis
    Polishchuk, Elena V., Merolla, Assunta, Lichtmannegger, Josef, Romano, Alessia, Indrieri, Alessia, Ilyechova, Ekaterina Y., Concilli, Mafalda, De Cegli, Rossella, Crispino, Roberta, Mariniello, Marta et al. · 2019 · Gastroenterology
71. The Landscape of Isoform Switches in Human Cancers
    Kristoffer Vitting‐Seerup, Albin Sandelin · 2017 · Molecular Cancer Research
72. SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
    Jansen, Jitske, Reimer, Katharina C., Nagai, James S., Varghese, Finny S., Overheul, Gijs J., de Beer, Marit, Roverts, Rona, Daviran, Deniz, Fermin, Liline A.S., Willemsen, Brigith et al. · 2022 · Cell Stem Cell
73. Mitochondrial transfer from MSCs to T cells induces Treg differentiation and restricts inflammatory response
    Court, Angela C, Le‐Gatt, Alice, Luz‐Crawford, Patricia, Parra, Eliseo, Aliaga‐Tobar, Victor, Bátiz, Luis Federico, Contreras, Rafael A, Ortúzar, María Ignacia, Kurte, Mónica, Elizondo‐Vega, Roberto et al. · 2020 · The EMBO Reports
74. FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
    Jack D. Chan, Christina M. Scheffler, Isabelle Munoz, Kevin Sek, Joel N. Lee, Yukuan Huang, Kah Min Yap, Nicole Y. L. Saw, Jasmine Li, Amanda X.Y. Chen et al. · 2024 · Nature
75. Autonomous biomedical research with an artificial intelligence agent
    Kexin Huang, Serena Zhang, Hanchen Wang, Yuanhao Qu, Yingzhou Lu, Ryan Li, Yusuf Roohani, Lin Qiu, Shiyi Cao, G. L. Li et al. · 2026 · Science
76. Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome
    Bruno Chetaille, François Bertucci, Pascal Finetti, Benjamin Esterni, Aspasia Stamatoullas, Jean Michel Picquenot, Marie Christine Copin, Franck Morschhauser, Olivier Casasnovas, Tony Petrella et al. · 2008 · Blood
77. Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
    Zichen Wang, Caroline D. Monteiro, Kathleen M. Jagodnik, Nicolas Fernandez, Gregory W. Gundersen, Andrew D. Rouillard, Sherry L. Jenkins, Axel S. Feldmann, Kevin S. Hu, Michael G. McDermott et al. · 2016 · Nature Communications
78. Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex
    Ana Uzquiano, Amanda J. Kedaigle, Martina Pigoni, Bruna da Silveira Paulsen, Xian Adiconis, Kwanho Kim, Tyler Faits, Surya Nagaraja, Noelia Antón-Bolaños, Chiara Gerhardinger et al. · 2022 · Cell
79. Functional interpretation of single cell similarity maps
    David DeTomaso, Matthew G. Jones, Meena Subramaniam, Tal Ashuach, Chun Ye, Nir Yosef · 2019 · Nature Communications
80. Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
    Xiaoming Dai, Xia Bu, Yang Gao, Jianping Guo, Jia Hu, Cong Jiang, Zhao Zhang, Kexin Xu, Jinzhi Duan, Shaohui He et al. · 2021 · Molecular Cell
81. Vorasidenib and ivosidenib in IDH1-mutant low-grade glioma: a randomized, perioperative phase 1 trial
    Ingo K. Mellinghoff, Min Lu, Patrick Yung Wen, Jennie Webster Taylor, Elizabeth Anne Maher, Isabel Arrillaga‐Romany, Katherine B. Peters, Benjamin M. Ellingson, Marc K. Rosenblum, Saewon Chun et al. · 2023 · Nature Medicine
82. Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
    German COVID-19 Omics Initiative (DeCOI), Aschenbrenner, Anna C., Mouktaroudi, Maria, Krämer, Benjamin, Oestreich, Marie, Antonakos, Nikolaos, Nuesch-Germano, Melanie, Gkizeli, Konstantina, Bonaguro, Lorenzo, Reusch, Nico et al. · 2021 · Genome Medicine
83. Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease
    Thomas J. Scriba, Adam Penn‐Nicholson, Smitha Shankar, Tom Hraha, Ethan G. Thompson, David Sterling, Elisa Nemes, Fatoumatta Darboe, Sara Suliman, Lynn M. Amon et al. · 2017 · PLoS Pathogens
84. CYCLOPS reveals human transcriptional rhythms in health and disease
    Ron C. Anafi, Lauren J. Francey, John B. Hogenesch, Junhyong Kim · 2017 · Proceedings of the National Academy of Sciences
85. Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells
    Mario Witkowski, Caroline Tizian, Marta Ferreira‐Gomes, Daniela Niemeyer, Terry C. Jones, Frederik Heinrich, Stefan Frischbutter, Stefan Angermair, Thordis Hohnstein, Irene Mattiola et al. · 2021 · Nature
86. GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data
    Shani Ben-Ari Fuchs, Iris Lieder, Gil Stelzer, Yaron Mazor, Ella Buzhor, Sergey Kaplan, Yoel Bogoch, Inbar Plaschkes, Alina Shitrit, Noa Rappaport et al. · 2016 · OMICS A Journal of Integrative Biology
87. Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases
    Ilya Korsunsky, Kevin Wei, Mathilde Pohin, Edy Yong Kim, Francesca Barone, Triin Major, Emily Taylor, Rahul Prashanth Ravindran, Samuel Kemble, Gerald F.M. Watts et al. · 2022 · Med
88. Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy
    Alejandro Jiménez-Sánchez, Paulina Cybulska, Katherine LaVigne Mager, Simon Koplev, Oliver M. Cast, Dominique‐Laurent Couturier, Danish Memon, Pier Selenica, Ines Nikolovski, Yousef Mazaheri et al. · 2020 · Nature Genetics
89. Impaired humoral and cellular immunity after SARS-CoV-2 BNT162b2 (tozinameran) prime-boost vaccination in kidney transplant recipients
    Arne Sattler, Eva Vanessa Schrezenmeier, U. Weber, Alexander Potekhin, Friederike Bachmann, Henriette Straub-Hohenbleicher, Klemens Budde, Elena Storz, Vanessa Proß, Yasmin Bergmann et al. · 2021 · Journal of Clinical Investigation
90. The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression
    Yashar S. Niknafs, Sumin Han, Teng Ma, Corey Wayne Speers, Chao Zhang, Kari Wilder-Romans, Matthew K. Iyer, Sethuramasundaram Pitchiaya, Rohit Malik, Yasuyuki Hosono et al. · 2016 · Nature Communications
91. Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging
    Marion Claudia Salzer, Atefeh Lafzi, Antonio Berenguer, Catrin Youssif, Andrés Castellanos‐Martín, Guiomar Solanas, Francisca Oliveira Peixoto, Camille Stephan‐Otto Attolini, Neus Prats, Mònica Aguilera et al. · 2018 · Cell
92. Serum Biomarkers Identify Patients Who Will Develop Inflammatory Bowel Diseases Up to 5 Years Before Diagnosis
    Joana Torres, Francesca Petralia, Takahiro Sato, Pei Wang, Shannon Telesco, Rok Seon Choung, Richard S Strauss, Xiao-jun Li, Renée M. Laird, Ramiro L. Gutiérrez et al. · 2020 · Gastroenterology
93. Frequent aneuploidy in primary human T cells after CRISPR–Cas9 cleavage
    Alessio David Nahmad, Eli Reuveni, Ella Goldschmidt, Tamar Tenne, Meytal Liberman, Miriam Horovitz‐Fried, Rami Khosravi, Hila Kobo, Eyal Reinstein, Asaf Madi et al. · 2022 · Nature Biotechnology
94. STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma
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