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Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration
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Disruption or dysfunction of MAMs is associated with a variety of pathophysiological conditions, including neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.
“Disruption of contact between the mitochondria and ER is associated with a variety of pathophysiological conditions including neurodegenerative diseases.”
From The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs (2020) · cites this paper as [19]
Impairment or perturbation of MAM function has been implicated in several neurodegenerative disease conditions.
“While impairment or perturbation of MAM function has been implicated in several neurodegenerative disease conditions [13–20, 76], the contributing underlying mechanism(s) remain unknown.”
From The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs (2020) · cites this paper as [19]
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Oligodendroglia metabolically support axons and contribute to neurodegeneration
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Stendel, C., Roos, A., Kleine, H., Arnaud, E., Özçelik, M., Sidiropoulos, P. N. M., Zenker, J., Schüpfer, F., Lehmann, U., Sobota, R. M., et al. (2010) · Brain · doi:10.1093/brain/awq168 · Cited by 102
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Cited by
Sorted by citations
Interaction of Mitochondrial Calcium and ROS in Neurodegeneration
Baev, A. Y., Vinokurov, A. Y., Novikova, I. N., Dremin, V. V., Potapova, E. V., & Abramov, A. Y. (2022) · Cells · doi:10.3390/cells11040706 · Cited by 162
Wang, W.-X., Prajapati, P., Nelson, P. T., & Springer, J. E. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-01937-y · Cited by 49
Metadata
- Authors
- Bernard-Marissal, N., Médard, J.-J., Azzedine, H., & Chrast, R.
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-02-10
- Volume
- 138
- Issue
- 4
- Pages
- 875-890
- ISSN
- 1460-2156
- 0006-8950
- Cited by
- 210
- References
- 3
- Language
- en
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