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Cited by 423

The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.

Small non-coding RNA and cancer

Open access
Romano, Giulia, Veneziano, Dario, Acunzo, Mario, Croce, Carlo M.·2017·Carcinogenesis

Abstract

The ENCODE project has reported that at least 80% of the human genome is biologically active, yet only a small part of human DNA encodes for protein. The massive amount of RNA transcribed but not translated into protein can be classified as housekeeping RNA (such as rRNA, tRNA) and regulatory RNA (such as miRNA, piRNA, lncRNA). Small non-coding RNAs, in particular, have been the focus of many studies in the last 20 years and their fundamental role in many human diseases is currently well established. Inter alia, their role in cancer development and progression, as well as in drug resistance, is being increasingly investigated. In this review, focusing our attention on recent research results, we provide an overview of the four large classes of small non-coding RNAs, namely, miRNAs, piRNAs, snoRNA and the new class of tRNA-derived fragments, highlighting their fundamental role in cancer and their potential as diagnostic and prognostic biomarkers.

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Crossref · 10.1093/carcin/bgx026

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Metadata

Authors
Romano, G., Veneziano, D., Acunzo, M., & Croce, C. M.
Venue
Carcinogenesis
Published
2017-04-26
Volume
38
Issue
5
Pages
485-491
ISSN
  • 0143-3334 (ISSN-L)
  • 1460-2180
OpenAlex
W2608190552
Cited by
423
References
80
FWCI
11.30
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Small non-coding RNA and cancer. https://app.cochat.ai/papers/10.1093/carcin/bgx026
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Romano, G., Veneziano, D., Acunzo, M., & Croce, C. M. (2017). Small non-coding RNA and cancer. Carcinogenesis. https://doi.org/10.1093/carcin/bgx026

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.