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Case Definitions, Diagnostic Algorithms, and Priorities in Encephalitis: Consensus Statement of the International Encephalitis Consortium

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Venkatesan, A., Tunkel, A. R., Bloch, K. C., Lauring, A. S., Sejvar, J., Bitnun, A., Stahl, J-P., Mailles, A., Drebot, M., Rupprecht, C. E., Yoder, J., Cope, J. R., Wilson, M. R., Whitley, R. J., Sullivan, J., Granerod, J., Jones, C., Eastwood, K., Ward, K. N., Durrheim, D. N., Solbrig, M. V., Guo-Dong, L., Glaser, C. A., on behalf of the International Encephalitis Consortium, Sheriff, Heather, Brown, David, Farnon, Eileen, Messenger, Sharon, Paterson, Beverley, Soldatos, Ariane, Roy, Sharon, Visvesvara, Govinda, Beach, Michael, Nasci, Roger, Pertowski, Carol, Schmid, Scott, Rascoe, Lisa, Montgomery, Joel, Tong, Suxiang, Breiman, Robert, Franka, Richard, Keuhnert, Matt, Angulo, Fred, Cherry, James·2013·Clinical Infectious Diseases
DOI 10.1093/cid/cit458
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Abstract

BACKGROUND: Encephalitis continues to result in substantial morbidity and mortality worldwide. Advances in diagnosis and management have been limited, in part, by a lack of consensus on case definitions, standardized diagnostic approaches, and priorities for research. METHODS: In March 2012, the International Encephalitis Consortium, a committee begun in 2010 with members worldwide, held a meeting in Atlanta to discuss recent advances in encephalitis and to set priorities for future study. RESULTS: We present a consensus document that proposes a standardized case definition and diagnostic guidelines for evaluation of adults and children with suspected encephalitis. In addition, areas of research priority, including host genetics and selected emerging infections, are discussed. CONCLUSIONS: We anticipate that this document, representing a synthesis of our discussions and supported by literature, will serve as a practical aid to clinicians evaluating patients with suspected encephalitis and will identify key areas and approaches to advance our knowledge of encephalitis.

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Metadata

Authors
Venkatesan, A., Tunkel, A. R., Bloch, K. C., Lauring, A. S., Sejvar, J., Bitnun, A., Stahl, J.-P., Mailles, A., Drebot, M., Rupprecht, C. E., Yoder, J., Cope, J. R., Wilson, M. R., Whitley, R. J., Sullivan, J., Granerod, J., Jones, C., Eastwood, K., Ward, K. N., Durrheim, D. N., Solbrig, M. V., Guo-Dong, L., Glaser, C. A., on behalf of the International Encephalitis Consortium, Sheriff, H., Brown, D., Farnon, E., Messenger, S., Paterson, B., Soldatos, A., Roy, S., Visvesvara, G., Beach, M., Nasci, R., Pertowski, C., Schmid, S., Rascoe, L., Montgomery, J., Tong, S., Breiman, R., Franka, R., Keuhnert, M., Angulo, F., & Cherry, J.
Venue
Clinical Infectious Diseases
Publisher
Oxford University Press (OUP)
Published
2013-07-15
Volume
57
Issue
8
Pages
1114-1128
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
DOI
10.1093/cid/cit458
OpenAlex
W2169697627
Cited by
1,197
References
9
FWCI
28.50
Type
journal article
Language
en
Open access
bronze

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Venkatesan, A., Tunkel, A. R., Bloch, K. C., Lauring, A. S., Sejvar, J., Bitnun, A., Stahl, J.-P., Mailles, A., Drebot, M., Rupprecht, C. E., Yoder, J., Cope, J. R., Wilson, M. R., Whitley, R. J., Sullivan, J., Granerod, J., Jones, C., Eastwood, K., Ward, K. N., . . . Cherry, J. (2013). Case Definitions, Diagnostic Algorithms, and Priorities in Encephalitis: Consensus Statement of the International Encephalitis Consortium. Clinical Infectious Diseases. https://doi.org/10.1093/cid/cit458

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